Erschienen in:
01.12.2010 | Original Article
Association of Depression with Antihypertensive Medication Adherence in Older Adults: Cross-Sectional and Longitudinal Findings from CoSMO
verfasst von:
Marie Krousel-Wood, M.D., M.S.P.H., Tareq Islam, M.P.H., Paul Muntner, Ph.D., Elizabeth Holt, Ph.D., M.P.H., Cara Joyce, M.S., Donald E. Morisky, Sc.D., M.S.P.H., Larry S. Webber, Ph.D., Edward D. Frohlich, M.D.
Erschienen in:
Annals of Behavioral Medicine
|
Ausgabe 3/2010
Einloggen, um Zugang zu erhalten
Abstract
Background
Little is known about the associations between depressive symptoms, social support and antihypertensive medication adherence in older adults.
Purpose
We evaluated the cross-sectional and longitudinal associations between depressive symptoms, social support and antihypertensive medication adherence in a large cohort of older adults.
Methods
A cohort of 2,180 older adults with hypertension was administered questionnaires, which included the Center for Epidemiologic Studies-Depression Scale, the Medical Outcomes Study Social Support Index, and the hypertension-specific Morisky Medication Adherence Scale at baseline and 1 year later.
Results
Overall, 14.1% of participants had low medication adherence, 13.0% had depressive symptoms, and 33.9% had low social support. After multivariable adjustment, the odds ratios that participants with depressive symptoms and low social support would have low medication adherence were 1.96 (95% confidence interval (CI) 1.43, 2.70) and 1.27 (95% CI 0.98, 1.65), respectively, at baseline and 1.87 (95% CI 1.32, 2.66) and 1.30 (95% CI 0.98, 1.72), respectively, at 1 year follow-up.
Conclusion
Depressive symptoms may be an important modifiable barrier to antihypertensive medication adherence in older adults