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01.12.2015 | Original Article

Cognitive Behavioral Stress Management for Healthy Women at Risk for Breast Cancer: a Novel Application of a Proven Intervention

verfasst von: Bonnie A. McGregor, Ph.D., Emily D. Dolan, Ph.D., Karly M. Murphy, M.S., Timothy S. Sannes, Ph.D., Krista B. Highland, Ph.D., Denise L. Albano, M.P.H., Alison A. Ward, Ph.D., Anna M. Charbonneau, Ph.D., Mary W. Redman, Ph.D., Rachel M. Ceballos, Ph.D.

Erschienen in: Annals of Behavioral Medicine | Ausgabe 6/2015

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Abstract

Background

Women at risk for breast cancer report elevated psychological distress, which has been adversely associated with cancer-relevant behaviors and biology.

Purpose

The present study sought to examine the effects of a 10-week cognitive behavioral stress management (CBSM) group intervention on distress among women with a family history of breast cancer.

Methods

Participants were randomly assigned to CBSM (N = 82) or a wait-list comparison group (N = 76). Baseline to postintervention effects of CBSM on depressive symptoms and perceived stress were examined using hierarchical regression.

Results

CBSM participants reported significantly lower posttreatment depressive symptoms (β = −0.17, p < 0.05) and perceived stress (β = −0.23, p < 0.05) than wait-list comparison participants. Additionally, greater relaxation practice predicted lower distress.

Conclusions

Group-based CBSM intervention is feasible and can reduce psychological distress among women with a family history of breast cancer. The present findings represent an encouraging avenue for the future application of CBSM. (Clinicaltrials.gov number NCT00121160)

Cukier YR et al. Factors associated with psychological distress among women of African descent at high risk for BRCA mutations. J Genet Couns. 2013; 22(1): 101-107.CrossRefPubMed

Patenaude AF et al. Young adult daughters of BRCA1/2 positive mothers: What do they know about hereditary cancer and how much do they worry? Psychooncology. 2013; 22(9): 2024-2031.CrossRefPubMed

Decruyenaere M et al. Cognitive representations of breast cancer, emotional distress and preventive health behaviour: A theoretical perspective. Psychooncology. 2000; 9(6): 528-536.CrossRefPubMed

Erblich J, Bovbjerg DH, Valdimarsdottir HB. Looking forward and back: Distress among women at familial risk for breast cancer. Ann Behav Med. 2000; 22(1): 53-59.CrossRefPubMed

Bennett P et al. Long-term cohort study of women at intermediate risk of familial breast cancer: Experiences of living at risk. Psycho-Oncology. 2010; 19(4): 390-398.CrossRefPubMed

Metcalfe KA et al. The impact of having a sister diagnosed with breast cancer on cancer-related distress and breast cancer risk perception. Cancer. 2013; 119(9): 1722-1728.CrossRefPubMed

McGregor BA et al. Optimism, perceived risk of breast cancer, and cancer worry among a community-based sample of women. Health Psychol. 2004; 23(4): 339-344.CrossRefPubMed

Fletcher KE et al. A path analysis of factors associated with distress among first-degree female relatives of women with breast cancer diagnosis. Health Psychol. 2006; 25(3): 413-424.CrossRefPubMed

Kim Y et al. Psychological distress among healthy women with family histories of breast cancer: Effects of recent life events. Psychooncology. 2004; 56: 182-191.

10.

Coyne JC et al. Distress and psychiatric morbidity among women from high-risk breast and ovarian cancer families. J Consult Clin Psychol. 2000; 68(5): 864-874.CrossRefPubMed

11.

Erblich J, Bovbjerg DH, Valdimarsdottir HB. Psychological distress, health beliefs, and frequency of breast self-examination. J Behav Med. 2000; 23(3): 277-292.CrossRefPubMed

12.

Bowen DJ et al. The relationship between perceived risk, affect, and health behaviors. Cancer Detect Prev. 2004; 28(6): 409-417.CrossRefPubMed

13.

Bovbjerg DH, Valdimarsdottir H. Familial cancer, emotional distress, and low natural cytotoxic activity in healthy women. Ann Oncol. 1993; 4(9): 745-752.PubMed

14.

Bovbjerg DH, et al. Stronger cortisol responses to laboratory stressors are independently predicted by breast-cancer specific intrusions and family history. In: The Annual Meeting and Scientific Sessions of the Society of Behavioral Medicine, San Francisco, CA; 2006.

15.

Flint MS, Bovbjerg DH. DNA damage as a result of psychological stress: Implications for breast cancer. Breast Cancer Res. 2012; 14(5): 320.PubMedCentralCrossRefPubMed

16.

James GD et al. The rate of urinary cortisol excretion at work is persistently elevated in women at familial risk for breast cancer. Am J Hum Biol. 2008; 20: 478-480.CrossRefPubMed

17.

Dawson DA, Grant BF, Ruan WJ. The association between stress and drinking: Modifying effects of gender and vulnerability. Alcohol Alcohol. 2005; 40(5): 453-460.CrossRefPubMed

18.

Wardle J et al. Stress, dietary restraint and food intake. J Psychosom Res. 2000; 48(2): 195-202.CrossRefPubMed

19.

Stetson BA et al. Prospective evaluation of the effects of stress on exercise adherence in community-residing women. Health Psychol. 1997; 16(6): 515-520.CrossRefPubMed

20.

Kouvonen A et al. Relationship between work stress and body mass index among 45,810 female and male employees. Psychosom Med. 2005; 67(4): 577-583.CrossRefPubMed

21.

Smith AW, Baum A, Wing RR. Stress and weight gain in parents of cancer patients. Int J Obes (Lond). 2005; 29(2): 244-250.CrossRef

22.

Lutgendorf SK, Sood AK. Biobehavioral factors and cancer progression: Physiological pathways and mechanisms. Psychosom Med. 2011; 73(9): 724-730.PubMedCentralCrossRefPubMed

23.

Dettenborn L et al. Heightened cortisol responses to daily stress in working women at familial risk for breast cancer. Biol Psychol. 2005; 69(2): 167-179.CrossRefPubMed

24.

Disis ML, Park KH. Immunomodulation of breast cancer via tumor antigen specific Th1. Cancer Res Treat. 2009; 41(3): 117-121.PubMedCentralCrossRefPubMed

25.

Moran TJ et al. The glucocorticoid receptor mediates a survival signal in human mammary epithelial cells. Cancer Res. 2000; 60(4): 867-872.PubMed

26.

Andersen MR et al. Breast cancer worry and mammography use by women with and without a family history in a population-based sample. Cancer Epidemiol Biomarkers Prev. 2003; 12(4): 314-320.PubMed

27.

Price MA et al. Predictors of breast cancer screening behavior in women with a strong family history of the disease. Breast Cancer Res Treat. 2010; 124(2): 509-519.CrossRefPubMed

28.

Esplen MJ et al. A multicenter study of supportive-expressive group therapy for women with BRCA1/BRCA2 mutations. Cancer. 2004; 101(10): 2327-2340.CrossRefPubMed

29.

Kash KM et al. Psychological counseling strategies for women at risk of breast cancer. J Natl Cancer Inst Monogr. 1995; 17: 73-79.PubMed

30.

Wellisch DK et al. Depression and anxiety symptoms in women at high risk for breast cancer: Pilot study of a group intervention. Am J Psychiatry. 1999; 156(10): 1644-1645.CrossRefPubMed

31.

Schwartz MD et al. The impact of a brief problem-solving training intervention for relatives of recently diagnosed breast cancer patients. Ann Behav Med. 1998; 20(1): 7-12.CrossRefPubMed

32.

Appleton S et al. A randomised controlled trial of a psychoeducational intervention for women at increased risk of breast cancer. Br J Cancer. 2004; 90(1): 41-47.PubMedCentralCrossRefPubMed

33.

Bovbjerg DH, Valdimarsdottir HB. Interventions for health individuals at familial risk for cancer. In: Baum A, Andersen BL, eds. Psychosocial Interventions for Cancer. Washington, D.C: American Psychological Association; 2001: 305-320.CrossRef

34.

Antoni MH et al. Reduction of cancer-specific thought intrusions and anxiety symptoms with a stress management intervention among women undergoing treatment for breast cancer. Am J Psychiatry. 2006; 163(10): 1791-1797.CrossRefPubMed

35.

Antoni MH et al. Cognitive-behavioral stress management intervention decreases the prevalence of depression and enhances benefit finding among women under treatment for early-stage breast cancer. Health Psychol. 2001; 20(1): 20-32.CrossRefPubMed

36.

Antoni MH et al. How stress management improves quality of life after treatment for breast cancer. J Consult Clin Psychol. 2006; 74(6): 1143-1152.CrossRefPubMed

37.

Black WC, Nease RF Jr, Tosteson AN. Perceptions of breast cancer risk and screening effectiveness in women younger than 50 years of age. J Natl Cancer Inst. 1995; 87(10): 720-731.CrossRefPubMed

38.

Lloyd S et al. Familial breast cancer: A controlled study of risk perception, psychological morbidity and health beliefs in women attending for genetic counselling. Br J Cancer. 1996; 74(3): 482-487.PubMedCentralCrossRefPubMed

39.

Cohen S, Williamson G. Perceived stress in a probability sample of the United States. In: Spacapam S, Oskamp S, eds. The Social Psychology of Health: Claremont Symposium on Applied Social Psychology. Newbury Park: Sage; 1988.

40.

Lerman C et al. Psychological side effects of breast cancer screening. Health Psychol. 1991; 10(4): 259-267.CrossRefPubMed

41.

DeSalvo KB et al. Assessing measurement properties of two single-item general health measures. Qual Life Res. 2006; 15(2): 191-201.CrossRefPubMed

42.

Holmes T. The Schedule of Recent Experience. 1986 ed. 1981, The Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle: The University of Washington Press.

43.

Gray MJ et al. Psychometric properties of the life events checklist. Assessment. 2004; 11(4): 330-341.CrossRefPubMed

44.

Pillow DR, Zautra AJ, Sandler I. Major life events and minor stressors: Identifying mediational links in the stress process. J Pers Soc Psychol. 1996; 70(2): 381-394.CrossRefPubMed

45.

Radloff LS. The CES-D scale: A self-report depression scale for research in the general population. Appl Psychol Meas. 1977; 1: 385-401.CrossRef

46.

Cohen S, Kamarck T, Mermelstein R. A global measure of perceived stress. J Health Soc Behav. 1983; 24(4): 385-396.CrossRefPubMed

47.

Weinstein N. Conceptualizing and Measuring Risk Perceptions. National Cancer Institute’s ‘‘Workshop on Conceptualizing (and Measuring) Perceived Risk’’, Washington, DC; 2003.

48.

Ruo B et al. Depressive symptoms and health-related quality of life: The Heart and Soul Study. JAMA. 2003; 290(2): 215-221.PubMedCentralCrossRefPubMed

49.

Reimherr FW et al. Antidepressant efficacy of sertraline: A double-blind, placebo- and amitriptyline-controlled, multicenter comparison study in outpatients with major depression. J Clin Psychiatry. 1990; 51(Suppl B): 18-27.PubMed

50.

Schuurmans J et al. A randomized, controlled trial of the effectiveness of cognitive-behavioral therapy and sertraline versus a waitlist control group for anxiety disorders in older adults. Am J Geriatr Psychiatry. 2006; 14(3): 255-263.CrossRefPubMed

51.

Avis NE et al. Quality of life in diverse groups of midlife women: Assessing the influence of menopause, health status and psychosocial and demographic factors. Qual Life Res. 2004; 13(5): 933-946.CrossRefPubMed

52.

Molloy GJ et al. Marital status, gender and cardiovascular mortality: Behavioural, psychological distress and metabolic explanations. Soc Sci Med. 2009; 69(2): 223-228.PubMedCentralCrossRefPubMed

53.

Costanzo ES et al. Adjusting to life after treatment: Distress and quality of life following treatment for breast cancer. Br J Cancer. 2007; 97(12): 1625-1631.PubMedCentralCrossRefPubMed

54.

Jim HS et al. History of major depressive disorder prospectively predicts worse quality of life in women with breast cancer. Ann Behav Med. 2012; 43(3): 402-408.PubMedCentralCrossRefPubMed

55.

Van Dorn RA et al. The relationship between outpatient mental health treatment and subsequent mental health symptoms and disorders in young adults. Adm Policy Ment Health. 2010; 37(6): 484-496.PubMedCentralCrossRefPubMed

56.

Lee YJ et al. Analysis of clinical trials by treatment actually received: Is it really an option? Stat Med. 1991; 10(10): 1595-1605.CrossRefPubMed

57.

Hays RD, Woolley JM. The concept of clinically meaningful difference in health-related quality-of-life research. How meaningful is it? PharmacoEconomics. 2000; 18(5): 419-423.CrossRefPubMed

58.

Norman GR, Sloan JA, Wyrwich KW. Interpretation of changes in health-related quality of life: The remarkable universality of half a standard deviation. Med Care. 2003; 41(5): 582-592.PubMed

59.

Beresford SA et al. Seattle 5 a Day worksite program to increase fruit and vegetable consumption. Prev Med. 2001; 32(3): 230-238.CrossRefPubMed

60.

Classen C et al. Supportive-expressive group therapy and distress in patients with metastatic breast cancer: A randomized clinical intervention trial. Arch Gen Psychiatry. 2001; 58(5): 494-501.CrossRefPubMed

61.

Cruess S et al. Reductions in herpes simplex virus type 2 antibody titers after cognitive behavioral stress management and relationships with neuroendocrine function, relaxation skills, and social support in HIV-positive men. Psychosom Med. 2000; 62(6): 828-837.CrossRefPubMed

62.

Lutgendorf SK et al. Cognitive-behavioral stress management decreases dysphoric mood and herpes simplex virus-type 2 antibody titers in symptomatic HIV-seropositive gay men. J Consult Clin Psychol. 1997; 65(1): 31-43.CrossRefPubMed

63.

Carmody J, Baer RA. Relationships between mindfulness practice and levels of mindfulness, medical and psychological symptoms and well-being in a mindfulness-based stress reduction program. J Behav Med. 2008; 31(1): 23-33.CrossRefPubMed

64.

Rosenzweig S et al. Mindfulness-based stress reduction for chronic pain conditions: Variation in treatment outcomes and role of home meditation practice. J Psychosom Res. 2010; 68(1): 29-36.CrossRefPubMed

65.

den Heijer M et al. Long-term psychological distress in women at risk for hereditary breast cancer adhering to regular surveillance: A risk profile. Psycho-oncology. 2013; 22(3): 598-604.CrossRef

Titel: Cognitive Behavioral Stress Management for Healthy Women at Risk for Breast Cancer: a Novel Application of a Proven Intervention
verfasst von: Bonnie A. McGregor, Ph.D.
Emily D. Dolan, Ph.D.
Karly M. Murphy, M.S.
Timothy S. Sannes, Ph.D.
Krista B. Highland, Ph.D.
Denise L. Albano, M.P.H.
Alison A. Ward, Ph.D.
Anna M. Charbonneau, Ph.D.
Mary W. Redman, Ph.D.
Rachel M. Ceballos, Ph.D.
Publikationsdatum: 01.12.2015
Verlag: Springer US
Erschienen in: Annals of Behavioral Medicine / Ausgabe 6/2015
Print ISSN: 0883-6612
Elektronische ISSN: 1532-4796
DOI: https://doi.org/10.1007/s12160-015-9726-z

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Cognitive Behavioral Stress Management for Healthy Women at Risk for Breast Cancer: a Novel Application of a Proven Intervention