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Erschienen in: Canadian Journal of Anesthesia/Journal canadien d'anesthésie 1/2012

Open Access 01.01.2012 | Reports of Original Investigations

Glidescope® video-laryngoscopy versus direct laryngoscopy for endotracheal intubation: a systematic review and meta-analysis

verfasst von: Donald E. G. Griesdale, MD, David Liu, MD, James McKinney, MD, Peter T. Choi, MD

Erschienen in: Canadian Journal of Anesthesia/Journal canadien d'anesthésie | Ausgabe 1/2012

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Abstract

Introduction

The Glidescope® video-laryngoscopy appears to provide better glottic visualization than direct laryngoscopy. However, it remains unclear if it translates into increased success with intubation.

Methods

We systematically searched electronic databases, conference abstracts, and article references. We included trials in humans comparing Glidescope® video-laryngoscopy to direct laryngoscopy regarding the glottic view, successful first-attempt intubation, and time to intubation. We generated pooled risk ratios or weighted mean differences across studies. Meta-regression was used to explore heterogeneity based on operator expertise and intubation difficulty.

Results

We included 17 trials with a total of 1,998 patients. The pooled relative risk (RR) of grade 1 laryngoscopy (vs ≥ grade 2) for the Glidescope® was 2.0 [95% confidence interval (CI) 1.5 to 2.5]. Significant heterogeneity was partially explained by intubation difficulty using meta-regression analysis (P = 0.003). The pooled RR for nondifficult intubations of grade 1 laryngoscopy (vs ≥ grade 2) was 1.5 (95% CI 1.2 to 1.9), and for difficult intubations it was 3.5 (95% CI 2.3 to 5.5). There was no difference between the Glidescope® and the direct laryngoscope regarding successful first-attempt intubation or time to intubation, although there was significant heterogeneity in both of these outcomes. In the two studies examining nonexperts, successful first-attempt intubation (RR 1.8, 95% CI 1.4 to 2.4) and time to intubation (weighted mean difference −43 sec, 95% CI −72 to −14 sec) were improved using the Glidescope®. These benefits were not seen with experts.

Conclusion

Compared to direct laryngoscopy, Glidescope® video-laryngoscopy is associated with improved glottic visualization, particularly in patients with potential or simulated difficult airways.
Literatur
1.
Zurück zum Zitat Cheney FW, Posner KL, Lee LA, Caplan RA, Domino KB. Trends in anesthesia-related death and brain damage: a closed claims analysis. Anesthesiology 2006; 105: 1081-6.PubMedCrossRef Cheney FW, Posner KL, Lee LA, Caplan RA, Domino KB. Trends in anesthesia-related death and brain damage: a closed claims analysis. Anesthesiology 2006; 105: 1081-6.PubMedCrossRef
2.
Zurück zum Zitat Rose DK, Cohen MM. The incidence of airway problems depends on the definition used. Can J Anaesth 1996; 43: 30-4.PubMedCrossRef Rose DK, Cohen MM. The incidence of airway problems depends on the definition used. Can J Anaesth 1996; 43: 30-4.PubMedCrossRef
3.
Zurück zum Zitat Ezri T, Weisenberg M, Khazin V, et al. Difficult laryngoscopy: incidence and predictors in patients undergoing coronary artery bypass surgery versus general surgery patients. J Cardiothorac Vasc Anesth 2003; 17: 321-4.PubMedCrossRef Ezri T, Weisenberg M, Khazin V, et al. Difficult laryngoscopy: incidence and predictors in patients undergoing coronary artery bypass surgery versus general surgery patients. J Cardiothorac Vasc Anesth 2003; 17: 321-4.PubMedCrossRef
4.
Zurück zum Zitat el-Ganzouri AR, McCarthy RJ, Tuman KJ, Tanck EN, Ivankovich AD. Preoperative airway assessment: predictive value of a multivariate risk index. Anesth Analg 1996; 82: 1197-204.PubMed el-Ganzouri AR, McCarthy RJ, Tuman KJ, Tanck EN, Ivankovich AD. Preoperative airway assessment: predictive value of a multivariate risk index. Anesth Analg 1996; 82: 1197-204.PubMed
5.
Zurück zum Zitat Crosby ET, Cooper RM, Douglas MJ, et al. The unanticipated difficult airway with recommendations for management. Can J Anaesth 1998; 45: 757-76.PubMedCrossRef Crosby ET, Cooper RM, Douglas MJ, et al. The unanticipated difficult airway with recommendations for management. Can J Anaesth 1998; 45: 757-76.PubMedCrossRef
6.
Zurück zum Zitat Karkouti K, Rose DK, Wigglesworth D, Cohen MM. Predicting difficult intubation: a multivariable analysis. Can J Anesth 2000; 47: 730-9.PubMedCrossRef Karkouti K, Rose DK, Wigglesworth D, Cohen MM. Predicting difficult intubation: a multivariable analysis. Can J Anesth 2000; 47: 730-9.PubMedCrossRef
7.
Zurück zum Zitat Rose DK, Cohen MM. The airway: problems and predictions in 18, 500 patients. Can J Anaesth 1994; 41: 372-83.PubMedCrossRef Rose DK, Cohen MM. The airway: problems and predictions in 18, 500 patients. Can J Anaesth 1994; 41: 372-83.PubMedCrossRef
8.
Zurück zum Zitat Rocke DA, Murray WB, Rout CC, Gouws E. Relative risk analysis of factors associated with difficult intubation in obstetric anesthesia. Anesthesiology 1992; 77: 67-73.PubMedCrossRef Rocke DA, Murray WB, Rout CC, Gouws E. Relative risk analysis of factors associated with difficult intubation in obstetric anesthesia. Anesthesiology 1992; 77: 67-73.PubMedCrossRef
9.
Zurück zum Zitat Shiga T, Wajima Z, Inoue T, Sakamoto A. Predicting difficult intubation in apparently normal patients: a meta-analysis of bedside screening test performance. Anesthesiology 2005; 103: 429-37.PubMedCrossRef Shiga T, Wajima Z, Inoue T, Sakamoto A. Predicting difficult intubation in apparently normal patients: a meta-analysis of bedside screening test performance. Anesthesiology 2005; 103: 429-37.PubMedCrossRef
10.
Zurück zum Zitat Graham CA, Beard D, Henry JM, McKeown DW. Rapid sequence intubation of trauma patients in Scotland. J Trauma 2004; 56: 1123-6.PubMedCrossRef Graham CA, Beard D, Henry JM, McKeown DW. Rapid sequence intubation of trauma patients in Scotland. J Trauma 2004; 56: 1123-6.PubMedCrossRef
11.
Zurück zum Zitat Griesdale DE, Bosma TL, Kurth T, Isac G, Chittock DR. Complications of endotracheal intubation in the critically ill. Intensive Care Med 2008; 34: 1835-42.PubMedCrossRef Griesdale DE, Bosma TL, Kurth T, Isac G, Chittock DR. Complications of endotracheal intubation in the critically ill. Intensive Care Med 2008; 34: 1835-42.PubMedCrossRef
12.
Zurück zum Zitat Schwartz DE, Matthay MA, Cohen NH. Death and other complications of emergency airway management in critically ill adults. A prospective investigation of 297 tracheal intubations. Anesthesiology 1995; 82: 367-76.PubMedCrossRef Schwartz DE, Matthay MA, Cohen NH. Death and other complications of emergency airway management in critically ill adults. A prospective investigation of 297 tracheal intubations. Anesthesiology 1995; 82: 367-76.PubMedCrossRef
13.
Zurück zum Zitat Benedetto WJ, Hess DR, Gettings E, et al. Urgent tracheal intubation in general hospital units: an observational study. J Clin Anesth 2007; 19: 20-4.PubMedCrossRef Benedetto WJ, Hess DR, Gettings E, et al. Urgent tracheal intubation in general hospital units: an observational study. J Clin Anesth 2007; 19: 20-4.PubMedCrossRef
14.
Zurück zum Zitat Nouruzi-Sedeh P, Schumann M, Groeben H. Laryngoscopy via Macintosh blade versus GlideScope: success rate and time for endotracheal intubation in untrained medical personnel. Anesthesiology 2009; 110: 32-7.PubMedCrossRef Nouruzi-Sedeh P, Schumann M, Groeben H. Laryngoscopy via Macintosh blade versus GlideScope: success rate and time for endotracheal intubation in untrained medical personnel. Anesthesiology 2009; 110: 32-7.PubMedCrossRef
15.
Zurück zum Zitat Sun DA, Warriner CB, Parsons DG, Klein R, Umedaly HS, Moult M. The GlideScope video laryngoscope: randomized clinical trial in 200 patients. Br J Anaesth 2005; 94: 381-4.PubMedCrossRef Sun DA, Warriner CB, Parsons DG, Klein R, Umedaly HS, Moult M. The GlideScope video laryngoscope: randomized clinical trial in 200 patients. Br J Anaesth 2005; 94: 381-4.PubMedCrossRef
16.
Zurück zum Zitat Jones PM, Armstrong KP, Armstrong PM, et al. A comparison of GlideScope videolaryngoscopy to direct laryngoscopy for nasotracheal intubation. Anesth Analg 2008; 107: 144-8.PubMedCrossRef Jones PM, Armstrong KP, Armstrong PM, et al. A comparison of GlideScope videolaryngoscopy to direct laryngoscopy for nasotracheal intubation. Anesth Analg 2008; 107: 144-8.PubMedCrossRef
17.
Zurück zum Zitat Liberati A, Altman DG, Tetzlaff J, et al. The PRISMA statement for reporting systematic reviews, meta-analyses of studies that evaluate healthcare interventions: explanation, elaboration. BMJ 2009; 339: b2700.PubMedCrossRef Liberati A, Altman DG, Tetzlaff J, et al. The PRISMA statement for reporting systematic reviews, meta-analyses of studies that evaluate healthcare interventions: explanation, elaboration. BMJ 2009; 339: b2700.PubMedCrossRef
18.
Zurück zum Zitat Cormack RS, Lehane J. Difficult tracheal intubation in obstetrics. Anaesthesia 1984; 39: 1105-11.PubMedCrossRef Cormack RS, Lehane J. Difficult tracheal intubation in obstetrics. Anaesthesia 1984; 39: 1105-11.PubMedCrossRef
19.
Zurück zum Zitat DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986; 7: 177-88.PubMedCrossRef DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986; 7: 177-88.PubMedCrossRef
20.
Zurück zum Zitat Cochran WG. The combination of estimates from different experiments. Biometrics 1954; 10: 101-29.CrossRef Cochran WG. The combination of estimates from different experiments. Biometrics 1954; 10: 101-29.CrossRef
21.
Zurück zum Zitat Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ 2003; 327: 557-60.PubMedCrossRef Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ 2003; 327: 557-60.PubMedCrossRef
22.
Zurück zum Zitat Thompson SG, Higgins JP. How should meta-regression analyses be undertaken and interpreted? Stat Med 2002; 21: 1559-73.PubMedCrossRef Thompson SG, Higgins JP. How should meta-regression analyses be undertaken and interpreted? Stat Med 2002; 21: 1559-73.PubMedCrossRef
23.
Zurück zum Zitat Lim Y, Yeo SW. A comparison of the GlideScope with the Macintosh laryngoscope for tracheal intubation in patients with simulated difficult airway. Anaesth Intensive Care 2005; 33: 243-7.PubMed Lim Y, Yeo SW. A comparison of the GlideScope with the Macintosh laryngoscope for tracheal intubation in patients with simulated difficult airway. Anaesth Intensive Care 2005; 33: 243-7.PubMed
24.
Zurück zum Zitat Serocki G, Bein B, Scholz J, Dorges V. Management of the predicted difficult airway: a comparison of conventional blade laryngoscopy with video-assisted blade laryngoscopy and the GlideScope. Eur J Anaesthesiol 2010; 27: 24-30.PubMedCrossRef Serocki G, Bein B, Scholz J, Dorges V. Management of the predicted difficult airway: a comparison of conventional blade laryngoscopy with video-assisted blade laryngoscopy and the GlideScope. Eur J Anaesthesiol 2010; 27: 24-30.PubMedCrossRef
25.
Zurück zum Zitat Siddiqui N, Katznelson R, Friedman Z. Heart rate/blood pressure response and airway morbidity following tracheal intubation with direct laryngoscopy, GlideScope and trachlight: a randomized control trial. Eur J Anaesthesiol 2009; 26: 740-5.PubMed Siddiqui N, Katznelson R, Friedman Z. Heart rate/blood pressure response and airway morbidity following tracheal intubation with direct laryngoscopy, GlideScope and trachlight: a randomized control trial. Eur J Anaesthesiol 2009; 26: 740-5.PubMed
26.
Zurück zum Zitat Malik MA, Subramaniam R, Maharaj CH, Harte BH, Laffey JG. Randomized controlled trial of the Pentax AWS, Glidescope, and Macintosh laryngoscopes in predicted difficult intubation. Br J Anaesth 2009; 103: 761-8.PubMedCrossRef Malik MA, Subramaniam R, Maharaj CH, Harte BH, Laffey JG. Randomized controlled trial of the Pentax AWS, Glidescope, and Macintosh laryngoscopes in predicted difficult intubation. Br J Anaesth 2009; 103: 761-8.PubMedCrossRef
27.
Zurück zum Zitat Teoh WH, Shah MK, Sia AT. Randomised comparison of Pentax AirwayScope and Glidescope for tracheal intubation in patients with normal airway anatomy. Anaesthesia 2009; 64: 1125-9.PubMedCrossRef Teoh WH, Shah MK, Sia AT. Randomised comparison of Pentax AirwayScope and Glidescope for tracheal intubation in patients with normal airway anatomy. Anaesthesia 2009; 64: 1125-9.PubMedCrossRef
28.
Zurück zum Zitat Malik MA, Maharaj CH, Harte BH, Laffey JG. Comparison of Macintosh, Truview EVO2, Glidescope, and Airwayscope laryngoscope use in patients with cervical spine immobilization. Br J Anaesth 2008; 101: 723-30.PubMedCrossRef Malik MA, Maharaj CH, Harte BH, Laffey JG. Comparison of Macintosh, Truview EVO2, Glidescope, and Airwayscope laryngoscope use in patients with cervical spine immobilization. Br J Anaesth 2008; 101: 723-30.PubMedCrossRef
29.
Zurück zum Zitat Robitaille A, Williams SR, Tremblay MH, Guilbert F, Theriault M, Drolet P. Cervical spine motion during tracheal intubation with manual in-line stabilization: direct laryngoscopy versus GlideScope videolaryngoscopy. Anesth Analg 2008; 106: 935-41.PubMedCrossRef Robitaille A, Williams SR, Tremblay MH, Guilbert F, Theriault M, Drolet P. Cervical spine motion during tracheal intubation with manual in-line stabilization: direct laryngoscopy versus GlideScope videolaryngoscopy. Anesth Analg 2008; 106: 935-41.PubMedCrossRef
30.
Zurück zum Zitat Xue FS, Zhang GH, Li XY, et al. Comparison of hemodynamic responses to orotracheal intubation with the GlideScope videolaryngoscope and the Macintosh direct laryngoscope. J Clin Anesth 2007; 19: 245-50.PubMedCrossRef Xue FS, Zhang GH, Li XY, et al. Comparison of hemodynamic responses to orotracheal intubation with the GlideScope videolaryngoscope and the Macintosh direct laryngoscope. J Clin Anesth 2007; 19: 245-50.PubMedCrossRef
31.
Zurück zum Zitat Turkstra TP, Craen RA, Pelz DM, Gelb AW. Cervical spine motion: a fluoroscopic comparison during intubation with lighted stylet, GlideScope, and Macintosh laryngoscope. Anesth Analg 2005; 101: 910-5.PubMedCrossRef Turkstra TP, Craen RA, Pelz DM, Gelb AW. Cervical spine motion: a fluoroscopic comparison during intubation with lighted stylet, GlideScope, and Macintosh laryngoscope. Anesth Analg 2005; 101: 910-5.PubMedCrossRef
32.
Zurück zum Zitat Bilehjani E, Fakhari S. Hemodynamic response to laryngoscopy in ischemic heart disease: Macintosh blade versus Glidescope videolaryngoscope. Rawal Med J 2009; 34: 151-4. Bilehjani E, Fakhari S. Hemodynamic response to laryngoscopy in ischemic heart disease: Macintosh blade versus Glidescope videolaryngoscope. Rawal Med J 2009; 34: 151-4.
33.
Zurück zum Zitat Morello G, Molino C, Sidoti MT, Parrinello L, Laudani A. Glidescope medium blade vs macintosh blade: laryngoscopy and intubation in 300 patients. Anesthesiology 2009: A475. Morello G, Molino C, Sidoti MT, Parrinello L, Laudani A. Glidescope medium blade vs macintosh blade: laryngoscopy and intubation in 300 patients. Anesthesiology 2009: A475.
34.
Zurück zum Zitat Vernick C, Audu P, Mandato P, Heitz J, Bader S. Comparing the Glidescope (GL) with Macintosh laryngoscope (Mac) for intubating difficult airway. Anesthesiology 2006: A534. Vernick C, Audu P, Mandato P, Heitz J, Bader S. Comparing the Glidescope (GL) with Macintosh laryngoscope (Mac) for intubating difficult airway. Anesthesiology 2006: A534.
35.
Zurück zum Zitat Yeatts D, Grissom T, Dutton R, et al. Video laryngoscopy does not improve outcomes in emergency intubation. Crit Care Med 2010: A929. Yeatts D, Grissom T, Dutton R, et al. Video laryngoscopy does not improve outcomes in emergency intubation. Crit Care Med 2010: A929.
36.
Zurück zum Zitat Shimada M, Hirabayashi Y, Seo N. Nasotracheal intubation using GlideScope videolaryngoscope or Macintosh laryngoscope by novice laryngoscopists (Japanese). Masui 2010; 59: 1318-20.PubMed Shimada M, Hirabayashi Y, Seo N. Nasotracheal intubation using GlideScope videolaryngoscope or Macintosh laryngoscope by novice laryngoscopists (Japanese). Masui 2010; 59: 1318-20.PubMed
37.
Zurück zum Zitat Mihai R, Blair E, Kay H, Cook TM. A quantitative review and meta-analysis of performance of non-standard laryngoscopes and rigid fibreoptic intubation aids. Anaesthesia 2008; 63: 745-60.PubMedCrossRef Mihai R, Blair E, Kay H, Cook TM. A quantitative review and meta-analysis of performance of non-standard laryngoscopes and rigid fibreoptic intubation aids. Anaesthesia 2008; 63: 745-60.PubMedCrossRef
38.
Zurück zum Zitat Aziz MF, Healy D, Kheterpal S, Fu RF, Dillman D, Brambrink AM. Routine clinical practice effectiveness of the Glidescope in difficult airway management: an analysis of 2, 004 Glidescope intubations, complications, and failures from two institutions. Anesthesiology 2011; 114: 34-41.PubMedCrossRef Aziz MF, Healy D, Kheterpal S, Fu RF, Dillman D, Brambrink AM. Routine clinical practice effectiveness of the Glidescope in difficult airway management: an analysis of 2, 004 Glidescope intubations, complications, and failures from two institutions. Anesthesiology 2011; 114: 34-41.PubMedCrossRef
39.
Zurück zum Zitat Cooper RM, Pacey JA, Bishop MJ, McCluskey SA. Early clinical experience with a new videolaryngoscope (GlideScope) in 728 patients. Can J Anesth 2005; 52: 191-8.PubMedCrossRef Cooper RM, Pacey JA, Bishop MJ, McCluskey SA. Early clinical experience with a new videolaryngoscope (GlideScope) in 728 patients. Can J Anesth 2005; 52: 191-8.PubMedCrossRef
40.
Zurück zum Zitat Hirsch-Allen AJ, Ayas N, Mountain S, Dodek P, Peets A, Griesdale DE. Influence of residency training on multiple attempts at endotracheal intubation. Can J Anesth 2010; 57: 823-9.PubMedCrossRef Hirsch-Allen AJ, Ayas N, Mountain S, Dodek P, Peets A, Griesdale DE. Influence of residency training on multiple attempts at endotracheal intubation. Can J Anesth 2010; 57: 823-9.PubMedCrossRef
41.
Zurück zum Zitat Jaber S, Amraoui J, Lefrant JY, et al. Clinical practice and risk factors for immediate complications of endotracheal intubation in the intensive care unit: a prospective, multiple-center study. Crit Care Med 2006; 34: 2355-61.PubMedCrossRef Jaber S, Amraoui J, Lefrant JY, et al. Clinical practice and risk factors for immediate complications of endotracheal intubation in the intensive care unit: a prospective, multiple-center study. Crit Care Med 2006; 34: 2355-61.PubMedCrossRef
43.
Zurück zum Zitat American Heart Association. 2005 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Part 7.1: Adjuncts for airway control and ventilation. Circulation 2005; 112(24_suppl): IV-51-7. American Heart Association. 2005 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Part 7.1: Adjuncts for airway control and ventilation. Circulation 2005; 112(24_suppl): IV-51-7.
44.
Zurück zum Zitat Wayne MA, McDonnell M. Comparison of traditional versus video laryngoscopy in out-of-hospital tracheal intubation. Prehosp Emerg Care 2010; 14: 278-82.PubMedCrossRef Wayne MA, McDonnell M. Comparison of traditional versus video laryngoscopy in out-of-hospital tracheal intubation. Prehosp Emerg Care 2010; 14: 278-82.PubMedCrossRef
45.
Zurück zum Zitat Reade MC, Delaney A, Bailey MJ, Angus DC. Bench-to-bedside review: avoiding pitfalls in critical care meta-analysis-funnel plots, risk estimates, types of heterogeneity, baseline risk and the ecologic fallacy. Crit Care 2008; 12: 220.PubMedCrossRef Reade MC, Delaney A, Bailey MJ, Angus DC. Bench-to-bedside review: avoiding pitfalls in critical care meta-analysis-funnel plots, risk estimates, types of heterogeneity, baseline risk and the ecologic fallacy. Crit Care 2008; 12: 220.PubMedCrossRef
46.
Zurück zum Zitat Ioannidis JP, Trikalinos TA. The appropriateness of asymmetry tests for publication bias in meta-analyses: a large survey. CMAJ 2007; 176: 1091-6.PubMedCrossRef Ioannidis JP, Trikalinos TA. The appropriateness of asymmetry tests for publication bias in meta-analyses: a large survey. CMAJ 2007; 176: 1091-6.PubMedCrossRef
Metadaten
Titel
Glidescope® video-laryngoscopy versus direct laryngoscopy for endotracheal intubation: a systematic review and meta-analysis
verfasst von
Donald E. G. Griesdale, MD
David Liu, MD
James McKinney, MD
Peter T. Choi, MD
Publikationsdatum
01.01.2012
Verlag
Springer-Verlag
Erschienen in
Canadian Journal of Anesthesia/Journal canadien d'anesthésie / Ausgabe 1/2012
Print ISSN: 0832-610X
Elektronische ISSN: 1496-8975
DOI
https://doi.org/10.1007/s12630-011-9620-5

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