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Erschienen in: The Journal of Obstetrics and Gynecology of India 2/2019

10.08.2018 | Original Article

An Analysis of Cause of Stillbirth in a Tertiary Care Hospital of Delhi: A Contribution to the WHO SEARO Project

verfasst von: Abha Singh, Manisha Kumar

Erschienen in: The Journal of Obstetrics and Gynecology of India | Ausgabe 2/2019

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Abstract

Background

Over 98% of the world’s total stillbirths are believed to occur in developing countries and still have received very little research, programmatic or policy attention.

Aims and Objective

To collect data on epidemiological profile of cases experiencing stillbirths, to assess the associated antenatal high risk factors present and to find out the probable cause of stillbirth.

Materials and Methods

This was a cross-sectional, observational study, which was done as part of WHO SEARO project after ethical clearance. The study included all stillbirths which occurred in the hospital during the study period August 2015–February 2017. Antenatal records were reviewed; maternal investigations were done. Baby was examined after delivery. Pre-structured pro forma was filled for every case. Finally, the relevant condition found was classified under CODAC system of stillbirth classification.

Result

Out of 20,580 deliveries, 600 (2.9%) were stillborn. Maternal cause was noted in 145/600 (24.2%) cases, fetal cause was noted in 181/600 (30.2%), and placental and cord origins were suspected in 128/600 (21.3%) and 12/600 (2%) cases, respectively. In 72/600 (12.0%) cases the reason for stillbirth was unknown and unclassifiable. Among the maternal causes the most common was hypertension (89/600, 14.8%) followed by infection including fever (5.7%); the most common infection was hepatitis. Among the fetal causes birth defect was the most common (106/600, 17.7%) followed by extreme prematurity in 42/600 (7.0%).

Conclusion

Birth defects were the most important fetal cause of stillbirth; hypertension in pregnancy and fetal growth restriction were important associated factors.
Literatur
1.
Zurück zum Zitat Liu L-C, Wang Y-C, Mu-Hsien Yu, et al. Major risk factors for stillbirth in different trimesters of pregnancy: a systematic review. Taiwan J Obstet Gynecol. 2014;53:141–5.CrossRefPubMed Liu L-C, Wang Y-C, Mu-Hsien Yu, et al. Major risk factors for stillbirth in different trimesters of pregnancy: a systematic review. Taiwan J Obstet Gynecol. 2014;53:141–5.CrossRefPubMed
2.
Zurück zum Zitat McClure EM, Goldenberg RL. Stillbirth in developing countries: a review of causes, risk factors and prevention strategies. J Matern Fetal Neonatal Med. 2009;22(3):183–90.CrossRefPubMedCentralPubMed McClure EM, Goldenberg RL. Stillbirth in developing countries: a review of causes, risk factors and prevention strategies. J Matern Fetal Neonatal Med. 2009;22(3):183–90.CrossRefPubMedCentralPubMed
3.
Zurück zum Zitat Kumbhare SA, Maitra NK. Aetiological classification of stillbirths: a case control study. J Obstet Gynaecol India. 2016;66(6):420–5.CrossRefPubMed Kumbhare SA, Maitra NK. Aetiological classification of stillbirths: a case control study. J Obstet Gynaecol India. 2016;66(6):420–5.CrossRefPubMed
4.
Zurück zum Zitat DiMario S, Say L, Lincetto O. Risk factors for stillbirth in developing countries: a systematic review of the literature. Sex Transm Dis. 2007;34(7 Suppl):S11–21.CrossRef DiMario S, Say L, Lincetto O. Risk factors for stillbirth in developing countries: a systematic review of the literature. Sex Transm Dis. 2007;34(7 Suppl):S11–21.CrossRef
5.
Zurück zum Zitat McClure EM, Wright LL, Goldenberg RL, et al. The global network: a prospective study of stillbirths in developing countries. Am J Obstet Gynecol. 2007;197(3):247.e1-5.CrossRefPubMed McClure EM, Wright LL, Goldenberg RL, et al. The global network: a prospective study of stillbirths in developing countries. Am J Obstet Gynecol. 2007;197(3):247.e1-5.CrossRefPubMed
6.
Zurück zum Zitat Korde-Nayak VN, Gaikwad PR. Causes of stillbirth. J Obstet Gynecol India. 2018;58(4):314–8. Korde-Nayak VN, Gaikwad PR. Causes of stillbirth. J Obstet Gynecol India. 2018;58(4):314–8.
7.
Zurück zum Zitat Kochar PS, Dandona R, Kumar GA, et al. Population-based estimates of still birth, induced abortion and miscarriage in the Indian state of Bihar. BMC Pregnancy Childbirth. 2014;14:413.CrossRefPubMedCentralPubMed Kochar PS, Dandona R, Kumar GA, et al. Population-based estimates of still birth, induced abortion and miscarriage in the Indian state of Bihar. BMC Pregnancy Childbirth. 2014;14:413.CrossRefPubMedCentralPubMed
8.
Zurück zum Zitat Frøen JF, Pinar H, Flenady V, et al. Causes of death and associated conditions (Codac): a utilitarian approach to the classification of perinatal deaths. BMC Pregnancy Childbirth. 2009;10(9):22.CrossRef Frøen JF, Pinar H, Flenady V, et al. Causes of death and associated conditions (Codac): a utilitarian approach to the classification of perinatal deaths. BMC Pregnancy Childbirth. 2009;10(9):22.CrossRef
9.
Zurück zum Zitat Korejo R, Bhutta S, Noorani KJ, et al. An audit and trends of perinatal mortality at the Jinnah Postgraduate Medical Centre, Karachi. J Pak Med Assoc. 2007;57(4):168–72.PubMed Korejo R, Bhutta S, Noorani KJ, et al. An audit and trends of perinatal mortality at the Jinnah Postgraduate Medical Centre, Karachi. J Pak Med Assoc. 2007;57(4):168–72.PubMed
10.
Zurück zum Zitat Prassana N, Mahadevappa K, Antaratani RC, et al. Cause of death and associated conditions of stillbirths. Int J Reprod Contracept Obstet Gynecol. 2015;4(6):1970–4.CrossRef Prassana N, Mahadevappa K, Antaratani RC, et al. Cause of death and associated conditions of stillbirths. Int J Reprod Contracept Obstet Gynecol. 2015;4(6):1970–4.CrossRef
11.
Zurück zum Zitat Goldenberg RL, McClure EM, Saleem S, et al. Infection-related stillbirths. Lancet. 2010;6736(09):61712–8. Goldenberg RL, McClure EM, Saleem S, et al. Infection-related stillbirths. Lancet. 2010;6736(09):61712–8.
12.
Zurück zum Zitat Goldenberg RL, McClure EM, Bann CM. The relationship of intrapartum and antepartum stillbirth rates to measures of obstetric care in developed and developing countries. Acta Obstet Gynecol Scand. 2007;86(11):1303–9.CrossRefPubMed Goldenberg RL, McClure EM, Bann CM. The relationship of intrapartum and antepartum stillbirth rates to measures of obstetric care in developed and developing countries. Acta Obstet Gynecol Scand. 2007;86(11):1303–9.CrossRefPubMed
13.
Zurück zum Zitat Fauveau V. New indicator of quality of emergency obstetric and newborn care. Lancet. 2007;307:1310.CrossRef Fauveau V. New indicator of quality of emergency obstetric and newborn care. Lancet. 2007;307:1310.CrossRef
14.
Zurück zum Zitat Dandona R, Kumar GA, Kumar A, et al. Identification of factors associated with stillbirth in the Indian state of Bihar using verbal autopsy: a population-based study. PLoS Med. 2017;14(8):e1002363.CrossRefPubMedCentralPubMed Dandona R, Kumar GA, Kumar A, et al. Identification of factors associated with stillbirth in the Indian state of Bihar using verbal autopsy: a population-based study. PLoS Med. 2017;14(8):e1002363.CrossRefPubMedCentralPubMed
15.
Zurück zum Zitat Newtonraj A, Kaur M, Gupta M, et al. Level, causes, and risk factors of stillbirth: a population-based case control study from Chandigarh, India. BMC Pregnancy Childbirth. 2017;17(1):371.CrossRefPubMedCentralPubMed Newtonraj A, Kaur M, Gupta M, et al. Level, causes, and risk factors of stillbirth: a population-based case control study from Chandigarh, India. BMC Pregnancy Childbirth. 2017;17(1):371.CrossRefPubMedCentralPubMed
Metadaten
Titel
An Analysis of Cause of Stillbirth in a Tertiary Care Hospital of Delhi: A Contribution to the WHO SEARO Project
verfasst von
Abha Singh
Manisha Kumar
Publikationsdatum
10.08.2018
Verlag
Springer India
Erschienen in
The Journal of Obstetrics and Gynecology of India / Ausgabe 2/2019
Print ISSN: 0971-9202
Elektronische ISSN: 0975-6434
DOI
https://doi.org/10.1007/s13224-018-1161-1

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