Skip to main content
Erschienen in: Der Hautarzt 12/2017

20.11.2017 | Acne inversa | Übersichten

Acne inversa/Hidradenitis suppurativa: Ein Update

Erschienen in: Die Dermatologie | Ausgabe 12/2017

Einloggen, um Zugang zu erhalten

Zusammenfassung

Acne inversa (AI)/Hidradenitis suppurativa ist eine chronisch rezidivierende, immunvermittelte Dermatose mit dem Charakter einer Systemerkrankung, die durch tief sitzende entzündliche Knoten, Abszesse, Fisteln und unterminierte Narben in Hautarealen mit apokrinen Drüsen gekennzeichnet ist. Neben den Hautveränderungen zeigen zahlreiche AI-Patienten metabolische Veränderungen, Spondylarthritis und Depressionen. AI führt zu einer massiven Einschränkung der Lebensqualität und des Sexuallebens der Betroffenen und mündet oft in sozialem Rückzug, Stigmatisierung, Arbeitsplatzverlust und Suizidgedanken. In diesem Übersichtsbeitrag haben wir die wichtigsten Fakten zu AI zusammengefasst und schlagen einen einfachen Algorithmus für die Behandlung dieser Erkrankung vor.
Literatur
1.
Zurück zum Zitat Zouboulis CC, Del Marmol V, Mrowietz U et al (2015) Hidradenitis suppurativa/acne Inversa: criteria for diagnosis, severity assessment, classification and disease evaluation. Dermatology 231:184–190CrossRefPubMed Zouboulis CC, Del Marmol V, Mrowietz U et al (2015) Hidradenitis suppurativa/acne Inversa: criteria for diagnosis, severity assessment, classification and disease evaluation. Dermatology 231:184–190CrossRefPubMed
2.
Zurück zum Zitat Saunte DM, Boer J, Stratigos A et al (2015) Diagnostic delay in hidradenitis suppurativa is a global problem. Br J Dermatol 173:1546–1549CrossRefPubMed Saunte DM, Boer J, Stratigos A et al (2015) Diagnostic delay in hidradenitis suppurativa is a global problem. Br J Dermatol 173:1546–1549CrossRefPubMed
3.
Zurück zum Zitat Jemec GB, Kimball AB (2015) Hidradenitis suppurativa: epidemiology and scope of the problem. J Am Acad Dermatol 73:S4–S7CrossRefPubMed Jemec GB, Kimball AB (2015) Hidradenitis suppurativa: epidemiology and scope of the problem. J Am Acad Dermatol 73:S4–S7CrossRefPubMed
5.
Zurück zum Zitat Sabat R, Chanwangpong A, Schneider-Burrus S et al (2012) Increased prevalence of metabolic syndrome in patients with acne inversa. PLOS ONE 7:e31810CrossRefPubMedPubMedCentral Sabat R, Chanwangpong A, Schneider-Burrus S et al (2012) Increased prevalence of metabolic syndrome in patients with acne inversa. PLOS ONE 7:e31810CrossRefPubMedPubMedCentral
6.
Zurück zum Zitat Egeberg A, Gislason GH, Hansen PR (2016) Risk of major adverse cardiovascular events and all-cause mortality in patients with Hidradenitis Suppurativa. JAMA Dermatol 152:429–434CrossRefPubMed Egeberg A, Gislason GH, Hansen PR (2016) Risk of major adverse cardiovascular events and all-cause mortality in patients with Hidradenitis Suppurativa. JAMA Dermatol 152:429–434CrossRefPubMed
7.
Zurück zum Zitat Schneider-Burrus S, Witte-Haendel E, Christou D et al (2016) High prevalence of back pain and axial spondyloarthropathy in patients with hidradenitis suppurativa. Dermatology 232:606–612CrossRefPubMed Schneider-Burrus S, Witte-Haendel E, Christou D et al (2016) High prevalence of back pain and axial spondyloarthropathy in patients with hidradenitis suppurativa. Dermatology 232:606–612CrossRefPubMed
8.
Zurück zum Zitat Kurek A, Peters JEM, Sabat R, Sterry W, Schneider-Burrus S (2013) Depression is a frequent co-morbidity in patients with acne inversa. J Dtsch Dermatol Ges 11:743–749, 743–750PubMed Kurek A, Peters JEM, Sabat R, Sterry W, Schneider-Burrus S (2013) Depression is a frequent co-morbidity in patients with acne inversa. J Dtsch Dermatol Ges 11:743–749, 743–750PubMed
9.
Zurück zum Zitat Shavit E, Dreiher J, Freud T et al (2015) Psychiatric comorbidities in 3207 patients with hidradenitis suppurativa. J Eur Acad Dermatol Venereol 29:371–376CrossRefPubMed Shavit E, Dreiher J, Freud T et al (2015) Psychiatric comorbidities in 3207 patients with hidradenitis suppurativa. J Eur Acad Dermatol Venereol 29:371–376CrossRefPubMed
11.
Zurück zum Zitat Dantzer R, O’Connor JC, Freund GG, Johnson RW, Kelley KW (2008) From inflammation to sickness and depression: when the immune system subjugates the brain. Nat Rev Neurosci 9:46–56CrossRefPubMedPubMedCentral Dantzer R, O’Connor JC, Freund GG, Johnson RW, Kelley KW (2008) From inflammation to sickness and depression: when the immune system subjugates the brain. Nat Rev Neurosci 9:46–56CrossRefPubMedPubMedCentral
12.
Zurück zum Zitat Gelfand JM, Kimball AB, Mostow EN et al (2008) Patient-reported outcomes and health-care resource utilization in patients with psoriasis treated with etanercept: continuous versus interrupted treatment. Value Health 11:400–407CrossRefPubMed Gelfand JM, Kimball AB, Mostow EN et al (2008) Patient-reported outcomes and health-care resource utilization in patients with psoriasis treated with etanercept: continuous versus interrupted treatment. Value Health 11:400–407CrossRefPubMed
13.
Zurück zum Zitat Tyring S, Gottlieb A, Papp K et al (2006) Etanercept and clinical outcomes, fatigue, and depression in psoriasis: double-blind placebo-controlled randomised phase III trial. Lancet 367:29–35CrossRefPubMed Tyring S, Gottlieb A, Papp K et al (2006) Etanercept and clinical outcomes, fatigue, and depression in psoriasis: double-blind placebo-controlled randomised phase III trial. Lancet 367:29–35CrossRefPubMed
14.
Zurück zum Zitat Deckers IE, Benhadou F, Koldijk MJ et al (2017) Inflammatory bowel disease is associated with hidradenitis suppurativa: results from a multicenter cross-sectional study. J Am Acad Dermatol 76:49–53CrossRefPubMed Deckers IE, Benhadou F, Koldijk MJ et al (2017) Inflammatory bowel disease is associated with hidradenitis suppurativa: results from a multicenter cross-sectional study. J Am Acad Dermatol 76:49–53CrossRefPubMed
15.
Zurück zum Zitat Matusiak L, Bieniek A, Szepietowski JC (2010) Psychophysical aspects of hidradenitis suppurativa. Acta Derm Venereol 90:264–268CrossRefPubMed Matusiak L, Bieniek A, Szepietowski JC (2010) Psychophysical aspects of hidradenitis suppurativa. Acta Derm Venereol 90:264–268CrossRefPubMed
16.
Zurück zum Zitat Wolkenstein P, Loundou A, Barrau K et al (2007) Quality of life impairment in hidradenitis suppurativa: a study of 61 cases. J Am Acad Dermatol 56:621–623CrossRefPubMed Wolkenstein P, Loundou A, Barrau K et al (2007) Quality of life impairment in hidradenitis suppurativa: a study of 61 cases. J Am Acad Dermatol 56:621–623CrossRefPubMed
17.
Zurück zum Zitat Kurek A, Peters EM, Chanwangpong A et al (2012) Profound disturbances of sexual health in patients with acne inversa. J Am Acad Dermatol 67:422–428, 428 e421CrossRefPubMed Kurek A, Peters EM, Chanwangpong A et al (2012) Profound disturbances of sexual health in patients with acne inversa. J Am Acad Dermatol 67:422–428, 428 e421CrossRefPubMed
18.
Zurück zum Zitat Dufour DN, Emtestam L, Jemec GB (2014) Hidradenitis suppurativa: a common and burdensome, yet under-recognised, inflammatory skin disease. Postgrad Med J 90:216–221 (quiz 220)CrossRefPubMedPubMedCentral Dufour DN, Emtestam L, Jemec GB (2014) Hidradenitis suppurativa: a common and burdensome, yet under-recognised, inflammatory skin disease. Postgrad Med J 90:216–221 (quiz 220)CrossRefPubMedPubMedCentral
19.
Zurück zum Zitat Yasar NF, Uylas MU, Baspinar M et al (2016) Evaluating the use of hematological parameters in staging hidradenitis suppurativa. Wounds 28:87–91PubMed Yasar NF, Uylas MU, Baspinar M et al (2016) Evaluating the use of hematological parameters in staging hidradenitis suppurativa. Wounds 28:87–91PubMed
20.
Zurück zum Zitat Makris GM, Poulakaki N, Papanota AM et al (2017) Vulvar, perianal and perineal cancer after hidradenitis suppurativa: a systematic review and pooled analysis. Dermatol Surg 43:107–115CrossRefPubMed Makris GM, Poulakaki N, Papanota AM et al (2017) Vulvar, perianal and perineal cancer after hidradenitis suppurativa: a systematic review and pooled analysis. Dermatol Surg 43:107–115CrossRefPubMed
21.
Zurück zum Zitat Lapins J, Ye W, Nyren O, Emtestam L (2001) Incidence of cancer among patients with hidradenitis suppurativa. Arch Dermatol 137:730–734PubMed Lapins J, Ye W, Nyren O, Emtestam L (2001) Incidence of cancer among patients with hidradenitis suppurativa. Arch Dermatol 137:730–734PubMed
22.
Zurück zum Zitat Jourabchi N, Fischer AH, Cimino-Mathews A, Waters KM, Okoye GA (2017) Squamous cell carcinoma complicating a chronic lesion of hidradenitis suppurativa: a case report and review of the literature. Int Wound J 14:435–438CrossRefPubMed Jourabchi N, Fischer AH, Cimino-Mathews A, Waters KM, Okoye GA (2017) Squamous cell carcinoma complicating a chronic lesion of hidradenitis suppurativa: a case report and review of the literature. Int Wound J 14:435–438CrossRefPubMed
23.
24.
Zurück zum Zitat Williams ST, Busby RC, DeMuth RJ, Nelson H (1991) Perineal hidradenitis suppurativa: presentation of two unusual complications and a review. Ann Plast Surg 26:456–462CrossRefPubMed Williams ST, Busby RC, DeMuth RJ, Nelson H (1991) Perineal hidradenitis suppurativa: presentation of two unusual complications and a review. Ann Plast Surg 26:456–462CrossRefPubMed
25.
Zurück zum Zitat Kimball AB, Okun MM, Williams DA et al (2016) Two phase 3 trials of adalimumab for hidradenitis suppurativa. N Engl J Med 375:422–434CrossRefPubMed Kimball AB, Okun MM, Williams DA et al (2016) Two phase 3 trials of adalimumab for hidradenitis suppurativa. N Engl J Med 375:422–434CrossRefPubMed
26.
Zurück zum Zitat Cosmatos I, Matcho A, Weinstein R, Montgomery MO, Stang P (2013) Analysis of patient claims data to determine the prevalence of hidradenitis suppurativa in the United States. J Am Acad Dermatol 69:819CrossRefPubMed Cosmatos I, Matcho A, Weinstein R, Montgomery MO, Stang P (2013) Analysis of patient claims data to determine the prevalence of hidradenitis suppurativa in the United States. J Am Acad Dermatol 69:819CrossRefPubMed
27.
Zurück zum Zitat Vazquez BG, Alikhan A, Weaver AL, Wetter DA, Davis MD (2013) Incidence of hidradenitis suppurativa and associated factors: a population-based study of Olmsted County, Minnesota. J Invest Dermatol 133:97–103CrossRefPubMed Vazquez BG, Alikhan A, Weaver AL, Wetter DA, Davis MD (2013) Incidence of hidradenitis suppurativa and associated factors: a population-based study of Olmsted County, Minnesota. J Invest Dermatol 133:97–103CrossRefPubMed
28.
Zurück zum Zitat Revuz JE, Canoui-Poitrine F, Wolkenstein P et al (2008) Prevalence and factors associated with hidradenitis suppurativa: results from two case-control studies. J Am Acad Dermatol 59:596–601CrossRefPubMed Revuz JE, Canoui-Poitrine F, Wolkenstein P et al (2008) Prevalence and factors associated with hidradenitis suppurativa: results from two case-control studies. J Am Acad Dermatol 59:596–601CrossRefPubMed
29.
Zurück zum Zitat Jemec GB, Heidenheim M, Nielsen NH (1996) The prevalence of hidradenitis suppurativa and its potential precursor lesions. J Am Acad Dermatol 35:191–194CrossRefPubMed Jemec GB, Heidenheim M, Nielsen NH (1996) The prevalence of hidradenitis suppurativa and its potential precursor lesions. J Am Acad Dermatol 35:191–194CrossRefPubMed
30.
Zurück zum Zitat Jemec GB (1988) The symptomatology of hidradenitis suppurativa in women. Br J Dermatol 119:345–350CrossRefPubMed Jemec GB (1988) The symptomatology of hidradenitis suppurativa in women. Br J Dermatol 119:345–350CrossRefPubMed
31.
Zurück zum Zitat von Laffert M, Stadie V, Wohlrab J, Marsch WC (2011) Hidradenitis suppurativa/acne inversa: bilocated epithelial hyperplasia with very different sequelae. Br J Dermatol 164:367–371CrossRef von Laffert M, Stadie V, Wohlrab J, Marsch WC (2011) Hidradenitis suppurativa/acne inversa: bilocated epithelial hyperplasia with very different sequelae. Br J Dermatol 164:367–371CrossRef
32.
Zurück zum Zitat Wolk K, Warszawska K, Hoeflich C et al (2011) Deficiency of IL-22 contributes to a chronic inflammatory disease: pathogenetic mechanisms in acne inversa. J Immunol 186:1228–1239CrossRefPubMed Wolk K, Warszawska K, Hoeflich C et al (2011) Deficiency of IL-22 contributes to a chronic inflammatory disease: pathogenetic mechanisms in acne inversa. J Immunol 186:1228–1239CrossRefPubMed
33.
Zurück zum Zitat Asadullah K, Sabat R, Wiese A et al (1999) Interleukin-10 in cutaneous disorders: implications for its pathophysiological importance and therapeutic use. Arch Dermatol Res 291:628–636CrossRefPubMed Asadullah K, Sabat R, Wiese A et al (1999) Interleukin-10 in cutaneous disorders: implications for its pathophysiological importance and therapeutic use. Arch Dermatol Res 291:628–636CrossRefPubMed
34.
Zurück zum Zitat Wolk K, Witte E, Warszawska K et al (2009) The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: a novel immunological cascade with potential relevance in psoriasis. Eur J Immunol 39:3570–3581CrossRefPubMed Wolk K, Witte E, Warszawska K et al (2009) The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: a novel immunological cascade with potential relevance in psoriasis. Eur J Immunol 39:3570–3581CrossRefPubMed
35.
Zurück zum Zitat Sabat R, Ouyang W, Wolk K (2014) Therapeutic opportunities of the IL-22-IL-22R1 system. Nat Rev Drug Discov 13:21–38CrossRefPubMed Sabat R, Ouyang W, Wolk K (2014) Therapeutic opportunities of the IL-22-IL-22R1 system. Nat Rev Drug Discov 13:21–38CrossRefPubMed
36.
Zurück zum Zitat Matusiak L, Bieniek A, Szepietowski JC (2014) Bacteriology of hidradenitis suppurativa—which antibiotics are the treatment of choice? Acta Derm Venereol 94:699–702CrossRefPubMed Matusiak L, Bieniek A, Szepietowski JC (2014) Bacteriology of hidradenitis suppurativa—which antibiotics are the treatment of choice? Acta Derm Venereol 94:699–702CrossRefPubMed
37.
Zurück zum Zitat Ring HC, Thorsen J, Saunte DM et al (2017) The follicular skin microbiome in patients with hidradenitis suppurativa and healthy controls. JAMA Dermatol 153:897–905CrossRefPubMed Ring HC, Thorsen J, Saunte DM et al (2017) The follicular skin microbiome in patients with hidradenitis suppurativa and healthy controls. JAMA Dermatol 153:897–905CrossRefPubMed
38.
Zurück zum Zitat Kelly G, Hughes R, McGarry T et al (2015) Dysregulated cytokine expression in lesional and nonlesional skin in hidradenitis suppurativa. Br J Dermatol 173:1431–1439CrossRefPubMed Kelly G, Hughes R, McGarry T et al (2015) Dysregulated cytokine expression in lesional and nonlesional skin in hidradenitis suppurativa. Br J Dermatol 173:1431–1439CrossRefPubMed
39.
Zurück zum Zitat Lima AL, Karl I, Giner T et al (2016) Keratinocytes and neutrophils are important sources of proinflammatory molecules in hidradenitis suppurativa. Br J Dermatol 174:514–521CrossRefPubMed Lima AL, Karl I, Giner T et al (2016) Keratinocytes and neutrophils are important sources of proinflammatory molecules in hidradenitis suppurativa. Br J Dermatol 174:514–521CrossRefPubMed
41.
Zurück zum Zitat Chiricozzi A, Raimondo A, Lembo S et al (2016) Crosstalk between skin inflammation and adipose tissue-derived products: pathogenic evidence linking psoriasis to increased adiposity. Expert Rev Clin Immunol 12:1299–1308CrossRefPubMed Chiricozzi A, Raimondo A, Lembo S et al (2016) Crosstalk between skin inflammation and adipose tissue-derived products: pathogenic evidence linking psoriasis to increased adiposity. Expert Rev Clin Immunol 12:1299–1308CrossRefPubMed
42.
Zurück zum Zitat Karbach S, Croxford AL, Oelze M et al (2014) Interleukin 17 drives vascular inflammation, endothelial dysfunction, and arterial hypertension in psoriasis-like skin disease. Arterioscler Thromb Vasc Biol 34:2658–2668CrossRefPubMed Karbach S, Croxford AL, Oelze M et al (2014) Interleukin 17 drives vascular inflammation, endothelial dysfunction, and arterial hypertension in psoriasis-like skin disease. Arterioscler Thromb Vasc Biol 34:2658–2668CrossRefPubMed
43.
Zurück zum Zitat Wolk K, Sabat R (2016) Adipokines in psoriasis: an important link between skin inflammation and metabolic alterations. Rev Endocr Metab Disord 17:305–317CrossRefPubMed Wolk K, Sabat R (2016) Adipokines in psoriasis: an important link between skin inflammation and metabolic alterations. Rev Endocr Metab Disord 17:305–317CrossRefPubMed
44.
Zurück zum Zitat Sabat R, Wolk K (2015) Deciphering the role of interleukin-22 in metabolic alterations. Cell Biosci 15(5):68CrossRef Sabat R, Wolk K (2015) Deciphering the role of interleukin-22 in metabolic alterations. Cell Biosci 15(5):68CrossRef
46.
Zurück zum Zitat Kirschke J, Hessam S, Bechara FG (2015) Hidradenitis suppurativa/acne inversa: an update. Hautarzt 66:413–422CrossRefPubMed Kirschke J, Hessam S, Bechara FG (2015) Hidradenitis suppurativa/acne inversa: an update. Hautarzt 66:413–422CrossRefPubMed
47.
Zurück zum Zitat Sartorius K, Lapins J, Emtestam L, Jemec GB (2003) Suggestions for uniform outcome variables when reporting treatment effects in hidradenitis suppurativa. Br J Dermatol 149:211–213CrossRefPubMed Sartorius K, Lapins J, Emtestam L, Jemec GB (2003) Suggestions for uniform outcome variables when reporting treatment effects in hidradenitis suppurativa. Br J Dermatol 149:211–213CrossRefPubMed
48.
Zurück zum Zitat Kimball AB, Jemec GB, Yang M et al (2014) Assessing the validity, responsiveness and meaningfulness of the Hidradenitis Suppurativa Clinical Response (HiSCR) as the clinical endpoint for hidradenitis suppurativa treatment. Br J Dermatol 171:1434–1442CrossRefPubMed Kimball AB, Jemec GB, Yang M et al (2014) Assessing the validity, responsiveness and meaningfulness of the Hidradenitis Suppurativa Clinical Response (HiSCR) as the clinical endpoint for hidradenitis suppurativa treatment. Br J Dermatol 171:1434–1442CrossRefPubMed
49.
50.
Zurück zum Zitat Matusiak L, Bieniek A, Szepietowski JC (2009) Soluble interleukin-2 receptor serum level is a useful marker of hidradenitis suppurativa clinical staging. Biomarkers 14:432–437CrossRefPubMed Matusiak L, Bieniek A, Szepietowski JC (2009) Soluble interleukin-2 receptor serum level is a useful marker of hidradenitis suppurativa clinical staging. Biomarkers 14:432–437CrossRefPubMed
51.
Zurück zum Zitat Matusiak L, Salomon J, Nowicka-Suszko D, Bieniek A, Szepietowski JC (2015) Chitinase-3-like protein 1 (YKL-40): novel Biomarker of Hidradenitis Suppurativa disease activity? Acta Derm Venereol 95:736–737CrossRefPubMed Matusiak L, Salomon J, Nowicka-Suszko D, Bieniek A, Szepietowski JC (2015) Chitinase-3-like protein 1 (YKL-40): novel Biomarker of Hidradenitis Suppurativa disease activity? Acta Derm Venereol 95:736–737CrossRefPubMed
52.
Zurück zum Zitat Tsaousi A, Witte E, Witte K et al (2016) MMP8 is increased in lesions and blood of acne inversa patients: a potential link to skin destruction and metabolic alterations. Mediat Inflamm 2016:4097574CrossRef Tsaousi A, Witte E, Witte K et al (2016) MMP8 is increased in lesions and blood of acne inversa patients: a potential link to skin destruction and metabolic alterations. Mediat Inflamm 2016:4097574CrossRef
53.
Zurück zum Zitat Gener G, Canoui-Poitrine F, Revuz JE et al (2009) Combination therapy with clindamycin and rifampicin for hidradenitis suppurativa: a series of 116 consecutive patients. Dermatology 219:148–154CrossRefPubMed Gener G, Canoui-Poitrine F, Revuz JE et al (2009) Combination therapy with clindamycin and rifampicin for hidradenitis suppurativa: a series of 116 consecutive patients. Dermatology 219:148–154CrossRefPubMed
54.
Zurück zum Zitat Mendonca CO, Griffiths CE (2006) Clindamycin and rifampicin combination therapy for hidradenitis suppurativa. Br J Dermatol 154:977–978CrossRefPubMed Mendonca CO, Griffiths CE (2006) Clindamycin and rifampicin combination therapy for hidradenitis suppurativa. Br J Dermatol 154:977–978CrossRefPubMed
55.
Zurück zum Zitat van der Zee HH, Boer J, Prens EP, Jemec GB (2009) The effect of combined treatment with oral clindamycin and oral rifampicin in patients with hidradenitis suppurativa. Dermatology 219:143–147CrossRefPubMed van der Zee HH, Boer J, Prens EP, Jemec GB (2009) The effect of combined treatment with oral clindamycin and oral rifampicin in patients with hidradenitis suppurativa. Dermatology 219:143–147CrossRefPubMed
56.
Zurück zum Zitat Kimball AB, Kerdel F, Adams D et al (2012) Adalimumab for the treatment of moderate to severe Hidradenitis suppurativa: a parallel randomized trial. Ann Intern Med 157:846–855CrossRefPubMed Kimball AB, Kerdel F, Adams D et al (2012) Adalimumab for the treatment of moderate to severe Hidradenitis suppurativa: a parallel randomized trial. Ann Intern Med 157:846–855CrossRefPubMed
57.
Zurück zum Zitat Philipp S, Kokolakis G, Sabat R (2016) Systemic treatments for psoriasis and psoriatic arthritis. Hautarzt 67:464–471CrossRefPubMed Philipp S, Kokolakis G, Sabat R (2016) Systemic treatments for psoriasis and psoriatic arthritis. Hautarzt 67:464–471CrossRefPubMed
Metadaten
Titel
Acne inversa/Hidradenitis suppurativa: Ein Update
Publikationsdatum
20.11.2017
Schlagwort
Acne inversa
Erschienen in
Die Dermatologie / Ausgabe 12/2017
Print ISSN: 2731-7005
Elektronische ISSN: 2731-7013
DOI
https://doi.org/10.1007/s00105-017-4082-5

Weitere Artikel der Ausgabe 12/2017

Der Hautarzt 12/2017 Zur Ausgabe

Dermatoskopie - Fall des Monats

Auffällige Pigmentläsion an der Stirn

Leitlinien kompakt für die Dermatologie

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Hirsutismus bei PCOS: Laser- und Lichttherapien helfen

26.04.2024 Hirsutismus Nachrichten

Laser- und Lichtbehandlungen können bei Frauen mit polyzystischem Ovarialsyndrom (PCOS) den übermäßigen Haarwuchs verringern und das Wohlbefinden verbessern – bei alleiniger Anwendung oder in Kombination mit Medikamenten.

Bei schweren Reaktionen auf Insektenstiche empfiehlt sich eine spezifische Immuntherapie

Insektenstiche sind bei Erwachsenen die häufigsten Auslöser einer Anaphylaxie. Einen wirksamen Schutz vor schweren anaphylaktischen Reaktionen bietet die allergenspezifische Immuntherapie. Jedoch kommt sie noch viel zu selten zum Einsatz.

Auf diese Krankheiten bei Geflüchteten sollten Sie vorbereitet sein

22.04.2024 DGIM 2024 Nachrichten

Um Menschen nach der Flucht aus einem Krisengebiet bestmöglich medizinisch betreuen zu können, ist es gut zu wissen, welche Erkrankungen im jeweiligen Herkunftsland häufig sind. Dabei hilft eine Internetseite der CDC (Centers for Disease Control and Prevention).

Kein Abstrich bei chronischen Wunden ohne Entzündungszeichen!

16.04.2024 DGIM 2024 Nachrichten

Den Reflex, eine oberflächliche chronische Hautwunde ohne Entzündungszeichen in jedem Fall abzustreichen, sollte man nach einer neuen „Klug-entscheiden“-Empfehlung unterdrücken.

Update Dermatologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.