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Erschienen in: HNO 8/2010

01.08.2010 | Übersichten

Prophylaktische und therapeutische Vakzinen gegen humane Papillomviren

verfasst von: Dr. A.E. Albers, T.K. Hoffmann, J.P. Klussmann, A.M. Kaufmann

Erschienen in: HNO | Ausgabe 8/2010

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Zusammenfassung

Neben der rezidivierenden Papillomatose gilt inzwischen auch der kausale Zusammenhang zwischen Infektionen mit humanen Papillomviren (HPV) und einer Subgruppe von Plattenepithelkarzinom des Kopf-Hals-Bereichs als gesichert. Durch Einführung prophylaktischer HPV-Vakzinen für Mädchen gegen die häufigsten Hochrisiko-Typen darf künftig auch von einer Änderung der Prävalenz insbesondere oropharyngealer Karzinome bei Patientinnen gerechnet werden. Die Impfung gegen die wichtigsten Niedrigrisiko-HPV-Typen zeigte eine hohe Effektivität gegen Genitalwarzen und sollte auch eine Effektivität gegen Papillomatosen aufweisen. Neue Möglichkeiten der prophylaktischen HPV-Impfung sowie Entwicklungen und Hintergrund therapeutischer Vakzinen werden anhand der aktuellen Studienlage diskutiert.
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Metadaten
Titel
Prophylaktische und therapeutische Vakzinen gegen humane Papillomviren
verfasst von
Dr. A.E. Albers
T.K. Hoffmann
J.P. Klussmann
A.M. Kaufmann
Publikationsdatum
01.08.2010
Verlag
Springer-Verlag
Erschienen in
HNO / Ausgabe 8/2010
Print ISSN: 0017-6192
Elektronische ISSN: 1433-0458
DOI
https://doi.org/10.1007/s00106-010-2118-6

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