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01.04.2015 | Leitthema

Stress and tinnitus

verfasst von: Prof. Dr. B. Mazurek, A.J. Szczepek, S. Hebert

Erschienen in: HNO | Ausgabe 4/2015

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Abstract

Emotional stress is a constant companion of tinnitus patients, since this phantom sound can unfortunately be a very effective stressor. However, the mechanism of stress contribution to the onset or progression of tinnitus remains unknown. Here, we review the pathways induced by emotional stress and the outcome of their induction: corticosteroid-dependent changes in gene expression, epigenetic modulations, and impact of stress on neuronal plasticity and neurotransmission. Using clinical examples, we demonstrate the presence of emotional stress among tinnitus patients and we present methods to measure the degree of stress. The evidence causally linking emotional stress with tinnitus is still indirect—the main difficulty lies in the inaccessibility of human auditory tissues and the inability to directly measure tinnitus-induced psychological distress in animal models. However, we believe that translational research is the future way of filling this gap, finding the answers, and thereby improving both the diagnosis and treatment of tinnitus patients.

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Titel: Stress and tinnitus
verfasst von: Prof. Dr. B. Mazurek
A.J. Szczepek
S. Hebert
Publikationsdatum: 01.04.2015
Verlag: Springer Berlin Heidelberg
Erschienen in: HNO / Ausgabe 4/2015
Print ISSN: 0017-6192
Elektronische ISSN: 1433-0458
DOI: https://doi.org/10.1007/s00106-014-2973-7

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Springer Medizin

Stress and tinnitus

Abstract

Neu im Fachgebiet HNO

HNO-Op. auch mit über 90?

Intrakapsuläre Tonsillektomie gewinnt an Boden

Bilateraler Hörsturz hat eine schlechte Prognose

„Nur wer sich gut aufgehoben fühlt, kann auch für Patientensicherheit sorgen“

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Springer Medizin

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