Skip to main content
Erschienen in: Social Psychiatry and Psychiatric Epidemiology 8/2006

01.08.2006 | ORIGINAL PAPER

Subjective quality of life of patients with obsessive–compulsive disorder

verfasst von: Dr. med. Katarina Stengler-Wenzke, Michael Kroll, Herbert Matschinger, Matthias C. Angermeyer

Erschienen in: Social Psychiatry and Psychiatric Epidemiology | Ausgabe 8/2006

Einloggen, um Zugang zu erhalten

Abstract

Background

Obsessive–compulsive disorder (OCD) is the fourth most frequent diagnosis in psychiatry. Patients with OCD suffer from obsessive thinking and compulsive behavior, which impact their everyday life negatively.

Objective

Subjective quality of life (QoL) in patients with OCD was examined and compared to the general German population and to patients with schizophrenia.

Methods

Seventy-five patients, aged 21–72, with OCD (ICD 10 F42.0–F42.2) were recruited from the outpatient clinic for anxiety disorders at the Department of Psychiatry of the University of Leipzig. By means of the WHOQOL-BREF, QoL was assessed in patients with OCD in a representative sample of patients with schizophrenia and in a sample of the general population of Saxony/Germany.

Results

Compared with the general population, QoL in patients with OCDs was lower in all domains of the WHOQOL-BREF. Unexpectedly, QoL in patients with OCDs was lower in the domains “psychological well-being” and “social relationships” when compared with schizophrenia patients.

Conclusions

OCD has a substantial adverse effect on patients’ subjective QoL, which may be even greater than the adverse effect of schizophrenia. Therefore, it will be necessary to include interventions in the treatment of OCD aimed at improving residual deficits in psychosocial functioning and QoL.
Literatur
Zurück zum Zitat Aigner M, Forster-Streffleur S, Prause W, Freidl M, Weiss M, Bach M (2006) What does the WHOQOL-BREF measure? Measurement overlap between quality of life and depressive symptomatology in chronic somatoform pain disorder. Soc Psychiatry Psychiatr Epidemiol 41:81–86PubMedCrossRef Aigner M, Forster-Streffleur S, Prause W, Freidl M, Weiss M, Bach M (2006) What does the WHOQOL-BREF measure? Measurement overlap between quality of life and depressive symptomatology in chronic somatoform pain disorder. Soc Psychiatry Psychiatr Epidemiol 41:81–86PubMedCrossRef
Zurück zum Zitat Angermeyer MC, Kilian R, Matschinger H (2000) WHOQOL-100 und WHOQOL-BREF. Hogrefe, Göttingen Angermeyer MC, Kilian R, Matschinger H (2000) WHOQOL-100 und WHOQOL-BREF. Hogrefe, Göttingen
Zurück zum Zitat Angermeyer MC, Holzinger A, Stengler-Wenzke K (2002) Depression and quality of life: Results of a follow-up study. Int J Soc Psychiatry 48:189–199PubMedCrossRef Angermeyer MC, Holzinger A, Stengler-Wenzke K (2002) Depression and quality of life: Results of a follow-up study. Int J Soc Psychiatry 48:189–199PubMedCrossRef
Zurück zum Zitat Angermeyer MC, Kilian R (2005) Theoretical models of quality of life for mental disorders. In: Katschnig H, Freeman H, Sartorius N (eds) Quality of life in mental disorders. (2nd edn), Wiley, Newyork, pp 21–31 Angermeyer MC, Kilian R (2005) Theoretical models of quality of life for mental disorders. In: Katschnig H, Freeman H, Sartorius N (eds) Quality of life in mental disorders. (2nd edn), Wiley, Newyork, pp 21–31
Zurück zum Zitat Bobes J, Gonzalez MP, Bascaran MT, Arango C, Saiz PA, Bousono M (2001) Quality of life and disability in patients with obsessive–compulsive disorder. Eur Psychiatry 16:239–245PubMedCrossRef Bobes J, Gonzalez MP, Bascaran MT, Arango C, Saiz PA, Bousono M (2001) Quality of life and disability in patients with obsessive–compulsive disorder. Eur Psychiatry 16:239–245PubMedCrossRef
Zurück zum Zitat Brieger P, Rottig S, Marneros A (2004) Lebensqualität bei unipolar depressiven und bipolar affektiven Patienten [Quality of life in unipolar depressive and bipolar affective patients]. Psychiatr Prax 31:304–309PubMedCrossRef Brieger P, Rottig S, Marneros A (2004) Lebensqualität bei unipolar depressiven und bipolar affektiven Patienten [Quality of life in unipolar depressive and bipolar affective patients]. Psychiatr Prax 31:304–309PubMedCrossRef
Zurück zum Zitat Bystritsky A, Saxena S, Maidment K, Vapnik T, Tarlow G, Rosen R (1999) Quality-of-life changes among patients with obsessive–compulsive disorder in a partial hospitalization program. Psychiatr Serv 50:412–414PubMed Bystritsky A, Saxena S, Maidment K, Vapnik T, Tarlow G, Rosen R (1999) Quality-of-life changes among patients with obsessive–compulsive disorder in a partial hospitalization program. Psychiatr Serv 50:412–414PubMed
Zurück zum Zitat Bystritsky A, Liberman RP, Hwang S, Wallace CJ, Vapnik T, Maindment K, Saxena S (2001) Social functioning and quality of life comparisons between obsessive–compulsive and schizophrenic disorders. Depress Anxiety 14:214–218 PubMedCrossRef Bystritsky A, Liberman RP, Hwang S, Wallace CJ, Vapnik T, Maindment K, Saxena S (2001) Social functioning and quality of life comparisons between obsessive–compulsive and schizophrenic disorders. Depress Anxiety 14:214–218 PubMedCrossRef
Zurück zum Zitat Calvocoressi L, Libman D, Vegso SJ, McDougle CJ, Price LH (1998) Global functioning of inpatients with obsessive-compulsive disorder, schizophrenia, and major depression. Psychiatr Serv 49:379–381PubMed Calvocoressi L, Libman D, Vegso SJ, McDougle CJ, Price LH (1998) Global functioning of inpatients with obsessive-compulsive disorder, schizophrenia, and major depression. Psychiatr Serv 49:379–381PubMed
Zurück zum Zitat Cook JA, Leff HS, Blyler CR, Gold PB, Goldberg RW, Mueser KT, Toprac MG, McFarlane WR, Shafer MS, Blankertz LE, Dudek K, Razzano LA, Grey DD, Burke-Miller (2005) Results of a multisite randomized trial of supported employment interventions for individuals with severe mental illness. Arch Gen Psychiatry 62:505–512PubMedCrossRef Cook JA, Leff HS, Blyler CR, Gold PB, Goldberg RW, Mueser KT, Toprac MG, McFarlane WR, Shafer MS, Blankertz LE, Dudek K, Razzano LA, Grey DD, Burke-Miller (2005) Results of a multisite randomized trial of supported employment interventions for individuals with severe mental illness. Arch Gen Psychiatry 62:505–512PubMedCrossRef
Zurück zum Zitat Deacon BJ, Abramowitz JS (2005) The Yale-Brown Obsessive Compulsive Scale: factor analysis, construct validity, and suggestions for refinement. J Anxiety Disord 19:573–585PubMedCrossRef Deacon BJ, Abramowitz JS (2005) The Yale-Brown Obsessive Compulsive Scale: factor analysis, construct validity, and suggestions for refinement. J Anxiety Disord 19:573–585PubMedCrossRef
Zurück zum Zitat Franz M, Meyer T, Reber T, Gallhofer B (2000) The importance of social comparisons for high levels of subjective quality of life in chronic schizophrenic patients. Qual Life Res 9:481–489PubMedCrossRef Franz M, Meyer T, Reber T, Gallhofer B (2000) The importance of social comparisons for high levels of subjective quality of life in chronic schizophrenic patients. Qual Life Res 9:481–489PubMedCrossRef
Zurück zum Zitat Goodman WK, Price LH, Rasmussen SA, Mazure C, Fleischmann RL, Hill CL, Heninger GR, Charney DS (1989a) The Yale-Brown Obsessive–Compulsive Scale. I. Development, use, and reliability. Arch Gen Psychiatry 46:1006–1011 Goodman WK, Price LH, Rasmussen SA, Mazure C, Fleischmann RL, Hill CL, Heninger GR, Charney DS (1989a) The Yale-Brown Obsessive–Compulsive Scale. I. Development, use, and reliability. Arch Gen Psychiatry 46:1006–1011
Zurück zum Zitat Goodman WK, Price LH, Rasmussen SA, Mazure C, Delgado P, Heninger GR, Charney DS (1989b) The Yale-Brown Obsessive–Compulsive Scale. II. Validity. Arch Gen Psychiatry 46:1012–1016 Goodman WK, Price LH, Rasmussen SA, Mazure C, Delgado P, Heninger GR, Charney DS (1989b) The Yale-Brown Obsessive–Compulsive Scale. II. Validity. Arch Gen Psychiatry 46:1012–1016
Zurück zum Zitat Hansson L (1999) Advancing the concepts of quality of life. In: Priebe S, Oliver JPJ, Kaiser W (eds) Quality of life and mental health care. Wrightson, pp 19–47 Hansson L (1999) Advancing the concepts of quality of life. In: Priebe S, Oliver JPJ, Kaiser W (eds) Quality of life and mental health care. Wrightson, pp 19–47
Zurück zum Zitat Hollander E, Kwon JH, Stein DJ, Broatch J, Rowland CT, Himelein CA (1996) Obsessive–compulsive and spectrum disorders: overview and quality of life issues. J Clin Psychiatry 57:3–6PubMed Hollander E, Kwon JH, Stein DJ, Broatch J, Rowland CT, Himelein CA (1996) Obsessive–compulsive and spectrum disorders: overview and quality of life issues. J Clin Psychiatry 57:3–6PubMed
Zurück zum Zitat Jenike MA (2001) An update on obsessive-compulsive disorder. Bull Menninger Clin 65:4–25 (Review)PubMedCrossRef Jenike MA (2001) An update on obsessive-compulsive disorder. Bull Menninger Clin 65:4–25 (Review)PubMedCrossRef
Zurück zum Zitat Katschnig H (2000) Schizophrenia and quality of life. Acta Psychiatr Scand 407:33–37CrossRef Katschnig H (2000) Schizophrenia and quality of life. Acta Psychiatr Scand 407:33–37CrossRef
Zurück zum Zitat Katschnig H, Krautgartner M, Schrank B, Angermeyer MC (2006) Quality of life in depression. In: Katschnig H, Freeman H, Sartorius N (eds) Quality of life in mental disorders. (second edition), Wiley, Newyork, pp 129–140 Katschnig H, Krautgartner M, Schrank B, Angermeyer MC (2006) Quality of life in depression. In: Katschnig H, Freeman H, Sartorius N (eds) Quality of life in mental disorders. (second edition), Wiley, Newyork, pp 129–140
Zurück zum Zitat Kay SR, Fiszbein A, Opler LA (1987) The Positive and Negative Syndrome Scale (PANSS) for schizophrenia. Schizophr Bull 13:261–276PubMed Kay SR, Fiszbein A, Opler LA (1987) The Positive and Negative Syndrome Scale (PANSS) for schizophrenia. Schizophr Bull 13:261–276PubMed
Zurück zum Zitat Kilian R, Dietrich S, Toumi M, Angermeyer MC (2004) Quality of life in persons with schizophrenia in out-patient treatment with first- or second-generation antipsychotics. Acta Psychiatr Scand 110:108–118 PubMedCrossRef Kilian R, Dietrich S, Toumi M, Angermeyer MC (2004) Quality of life in persons with schizophrenia in out-patient treatment with first- or second-generation antipsychotics. Acta Psychiatr Scand 110:108–118 PubMedCrossRef
Zurück zum Zitat Koran LM, Thienemann ML, Davenport R (1996) Quality of life for patients with obsessive–compulsive disorder. Am J Psychiatry 153:783–788PubMed Koran LM, Thienemann ML, Davenport R (1996) Quality of life for patients with obsessive–compulsive disorder. Am J Psychiatry 153:783–788PubMed
Zurück zum Zitat Koran LM (2000) Quality of life in obsessive-compulsive disorder. Psychiatr Clin North Am 23:509–517PubMedCrossRef Koran LM (2000) Quality of life in obsessive-compulsive disorder. Psychiatr Clin North Am 23:509–517PubMedCrossRef
Zurück zum Zitat Kuehner C (2002) Subjective quality of life: validity issues with depressed patients. Acta Psychiatr Scand 106:62–70PubMedCrossRef Kuehner C (2002) Subjective quality of life: validity issues with depressed patients. Acta Psychiatr Scand 106:62–70PubMedCrossRef
Zurück zum Zitat Lochner C, Stein DJ (2003) Heterogeneity of obsessive–compulsive disorder: a literature review. Harv Rev Psychiatry 11:113–32PubMedCrossRef Lochner C, Stein DJ (2003) Heterogeneity of obsessive–compulsive disorder: a literature review. Harv Rev Psychiatry 11:113–32PubMedCrossRef
Zurück zum Zitat Lochner C, Mogotsi M, du Toit PL, Kaminer D, Niehaus DJ, Stein DJ (2003) Quality of life in anxiety disorders: a comparison of obsessive–compulsive disorder, social anxiety disorder, and panic disorder. Psychopathology 36:255–262PubMedCrossRef Lochner C, Mogotsi M, du Toit PL, Kaminer D, Niehaus DJ, Stein DJ (2003) Quality of life in anxiety disorders: a comparison of obsessive–compulsive disorder, social anxiety disorder, and panic disorder. Psychopathology 36:255–262PubMedCrossRef
Zurück zum Zitat Masellis M, Rector NA, Richter MA (2003) Quality of life in OCD: differential impact of obsessions, compulsions, and depression comorbidity. Can J Psychiatry 48:72–77PubMed Masellis M, Rector NA, Richter MA (2003) Quality of life in OCD: differential impact of obsessions, compulsions, and depression comorbidity. Can J Psychiatry 48:72–77PubMed
Zurück zum Zitat Mendlowicz MV, Stein MB (2000) Quality of life in individuals with anxiety disorders. Am J Psychiatry 157:669–682PubMedCrossRef Mendlowicz MV, Stein MB (2000) Quality of life in individuals with anxiety disorders. Am J Psychiatry 157:669–682PubMedCrossRef
Zurück zum Zitat Mendlowicz MV, Braga RJ, Marrocos RP, Figueira I (2005) Comorbidity and disability in outpatients with schizophrenia. Am J Psychiatry 162:400PubMedCrossRef Mendlowicz MV, Braga RJ, Marrocos RP, Figueira I (2005) Comorbidity and disability in outpatients with schizophrenia. Am J Psychiatry 162:400PubMedCrossRef
Zurück zum Zitat Moritz S, Rufer M, Fricke S, Karow A, Morfeld M, Jelinek L, Jacobsen D (2005) Quality of life in obsessive–compulsive disorder before and after treatment. Compr Psychiatry 46:453–459PubMedCrossRef Moritz S, Rufer M, Fricke S, Karow A, Morfeld M, Jelinek L, Jacobsen D (2005) Quality of life in obsessive–compulsive disorder before and after treatment. Compr Psychiatry 46:453–459PubMedCrossRef
Zurück zum Zitat Millet B, Kochman F, Gallarda T, Krebs MO, Demonfaucon F, Barrot I, Bourdel MC, Olie JP, Loo H, Hantouche EG (2004) Phenomenological and co-morbid features associated in obsessive–compulsive disorder: influence of age of onset. J Affect Dis 79:241–246PubMedCrossRef Millet B, Kochman F, Gallarda T, Krebs MO, Demonfaucon F, Barrot I, Bourdel MC, Olie JP, Loo H, Hantouche EG (2004) Phenomenological and co-morbid features associated in obsessive–compulsive disorder: influence of age of onset. J Affect Dis 79:241–246PubMedCrossRef
Zurück zum Zitat Rapaport MH, Clary C, Fayyad R, Endicott J (2005) Quality-of-life impairment in depressive and anxiety disorders. Am J Psychiatry 162:1171–1178PubMedCrossRef Rapaport MH, Clary C, Fayyad R, Endicott J (2005) Quality-of-life impairment in depressive and anxiety disorders. Am J Psychiatry 162:1171–1178PubMedCrossRef
Zurück zum Zitat Rössler W, Salize HJ, van Os J, Riecher-Rössler A (2005) Size of burden of schizophrenia and psychotic disorders. Eur Neuropsychopharmacol 15:399–409PubMedCrossRef Rössler W, Salize HJ, van Os J, Riecher-Rössler A (2005) Size of burden of schizophrenia and psychotic disorders. Eur Neuropsychopharmacol 15:399–409PubMedCrossRef
Zurück zum Zitat Rüesch P, Graf J, Meyer PC, Rössler W, Hell D (2004) Occupation, social support and quality of life in persons with schizophrenic or affective disorders. Soc Psychiatry Psychiatr Epidemiol 39:686–694PubMedCrossRef Rüesch P, Graf J, Meyer PC, Rössler W, Hell D (2004) Occupation, social support and quality of life in persons with schizophrenic or affective disorders. Soc Psychiatry Psychiatr Epidemiol 39:686–694PubMedCrossRef
Zurück zum Zitat Skantze K, Malm U, Dencker SJ, May PR, Corrigan P (1992) Comparison of quality of life with standard of living in schizophrenic out-patients. Br J Psychiatry 161:797–801PubMedCrossRef Skantze K, Malm U, Dencker SJ, May PR, Corrigan P (1992) Comparison of quality of life with standard of living in schizophrenic out-patients. Br J Psychiatry 161:797–801PubMedCrossRef
Zurück zum Zitat Stein DJ, Allen A, Bobes J (2000) Quality of life in obsessive–compulsive disorder. CNS Spectr 5:37–39 Stein DJ, Allen A, Bobes J (2000) Quality of life in obsessive–compulsive disorder. CNS Spectr 5:37–39
Zurück zum Zitat Steketee G (1997) Disability and family burden in obsessive-compulsive disorder. Can J Psychiatry 42:919–928PubMed Steketee G (1997) Disability and family burden in obsessive-compulsive disorder. Can J Psychiatry 42:919–928PubMed
Zurück zum Zitat Stengler-Wenzke K, Angermeyer MC (2002) Ambulante Gruppentherapie für Patienten mit Zwangserkrankungen und deren Angehörige [Behavioral group therapy for patients with OCD and family members]. Psychiatr Prax 29:136–141PubMedCrossRef Stengler-Wenzke K, Angermeyer MC (2002) Ambulante Gruppentherapie für Patienten mit Zwangserkrankungen und deren Angehörige [Behavioral group therapy for patients with OCD and family members]. Psychiatr Prax 29:136–141PubMedCrossRef
Zurück zum Zitat Stengler-Wenzke K, Angermeyer MC (2005) Inanspruchnahme von professioneller Hilfe von Patienten mit Zwangserkrankungen [Employment of professional help by patients with obsessive-compulsive disorders]. Psychiat Prax 32:195–201CrossRef Stengler-Wenzke K, Angermeyer MC (2005) Inanspruchnahme von professioneller Hilfe von Patienten mit Zwangserkrankungen [Employment of professional help by patients with obsessive-compulsive disorders]. Psychiat Prax 32:195–201CrossRef
Zurück zum Zitat Stengler-Wenzke K, Beck M, Holzinger A, Angermeyer MC (2004) Stigmaerfahrungen von Patienten mit Zwangserkrankungen [Stigma experiences of patients with obsessive compulsive disorders]. Fortschr Neurol Psychiatr 72:7–13PubMed Stengler-Wenzke K, Beck M, Holzinger A, Angermeyer MC (2004) Stigmaerfahrungen von Patienten mit Zwangserkrankungen [Stigma experiences of patients with obsessive compulsive disorders]. Fortschr Neurol Psychiatr 72:7–13PubMed
Zurück zum Zitat The WHO World Health Report: New understanding, new hope. WHO, Geneva, 2001 The WHO World Health Report: New understanding, new hope. WHO, Geneva, 2001
Zurück zum Zitat THE WHOQOL GROUP (1998) Development of the World Health Organization WHOQOL-BREF quality of life assessment. Soc Sci Med 28:551–558 THE WHOQOL GROUP (1998) Development of the World Health Organization WHOQOL-BREF quality of life assessment. Soc Sci Med 28:551–558
Zurück zum Zitat Ware JE, Sherbourne CD (1992) The MOS 36-Item Short-Form Health Survey (SF-36). I. Conceptual framework and item selection. Med Care 30:473–483PubMed Ware JE, Sherbourne CD (1992) The MOS 36-Item Short-Form Health Survey (SF-36). I. Conceptual framework and item selection. Med Care 30:473–483PubMed
Zurück zum Zitat Weissman MM, Bland RC, Canino GJ, Greenwald S, Hwu HG, Lee CK, Newman SC, Oakley-Browne MA, Rubio-Stipec M, Wickramaratne PJ, et al. (1994) The cross- national epidemiology of obsessive compulsive disorder. The Cross National Collaborative Group. J Clin Psychiatry 55:5–10 PubMed Weissman MM, Bland RC, Canino GJ, Greenwald S, Hwu HG, Lee CK, Newman SC, Oakley-Browne MA, Rubio-Stipec M, Wickramaratne PJ, et al. (1994) The cross- national epidemiology of obsessive compulsive disorder. The Cross National Collaborative Group. J Clin Psychiatry 55:5–10 PubMed
Zurück zum Zitat Wills TA (1981) Downward comparison principles in social psychology. Psychol Bull 90:245–271CrossRef Wills TA (1981) Downward comparison principles in social psychology. Psychol Bull 90:245–271CrossRef
Zurück zum Zitat World Health Organization (1993) The 10th revision of the International Classification of Diseases. Chapter V (F): Mental and behavioral disorders. Huber, Göttingen World Health Organization (1993) The 10th revision of the International Classification of Diseases. Chapter V (F): Mental and behavioral disorders. Huber, Göttingen
Zurück zum Zitat World Health Organization (1999) The “newly defined” burden of mental problems. Fact Sheets no217. WHO, Geneva World Health Organization (1999) The “newly defined” burden of mental problems. Fact Sheets no217. WHO, Geneva
Metadaten
Titel
Subjective quality of life of patients with obsessive–compulsive disorder
verfasst von
Dr. med. Katarina Stengler-Wenzke
Michael Kroll
Herbert Matschinger
Matthias C. Angermeyer
Publikationsdatum
01.08.2006
Erschienen in
Social Psychiatry and Psychiatric Epidemiology / Ausgabe 8/2006
Print ISSN: 0933-7954
Elektronische ISSN: 1433-9285
DOI
https://doi.org/10.1007/s00127-006-0077-8

Weitere Artikel der Ausgabe 8/2006

Social Psychiatry and Psychiatric Epidemiology 8/2006 Zur Ausgabe

Update Psychiatrie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.