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01.09.2011 | Original Article

Adolescent Kawasaki disease: usefulness of 64-slice CT coronary angiography for follow-up investigation

verfasst von: Iacopo Carbone, David Cannata, Emanuela Algeri, Nicola Galea, Alessandro Napoli, Andrea De Zorzi, Giovanna Bosco, Rita D’Agostino, Leon Menezes, Carlo Catalano, Roberto Passariello, Marco Francone

Erschienen in: Pediatric Radiology | Ausgabe 9/2011

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Abstract

Background

Kawasaki disease (KD) is a systemic vasculitis that mainly affects coronary arteries in children, and requires regular follow-up from the time of diagnosis.

Objective

To evaluate the feasibility of 64-slice CT angiography (CTA) for follow-up of patients with KD using previously performed invasive catheter coronary angiography (CCA) as reference standard.

Materials and methods

The study group comprised 12 patients (age 17.6 ± 2.9 years, mean±SD) with a diagnosis of KD and a previously performed CCA (interval, 32.6 ± 13.5 months) who underwent 64-slice cardiac CTA. The quality of the images for establishing the presence of coronary abnormalities was determined by two observers. The CTA findings were compared with those from the prior CCA.

Results

Adequate image quality was obtained in all patients. Mean effective dose for CTA was 6.56 ± 0.95 mSv. CTA allowed accurate identification, characterization and measurement of all coronary aneurysms (n = 32), stenoses (n = 3) and occlusions (n = 9) previously demonstrated by CCA. One patient with disease progression went on to have percutaneous coronary intervention.

Conclusion

Coronary lesions were reliably evaluated by 64-slice CTA in the follow-up of compliant patients with KD, reducing the need for repeated diagnostic invasive CCA. Hence, in an adequately selected patient population, the role of CCA could be limited almost only to therapeutic procedures.

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Titel: Adolescent Kawasaki disease: usefulness of 64-slice CT coronary angiography for follow-up investigation
verfasst von: Iacopo Carbone
David Cannata
Emanuela Algeri
Nicola Galea
Alessandro Napoli
Andrea De Zorzi
Giovanna Bosco
Rita D’Agostino
Leon Menezes
Carlo Catalano
Roberto Passariello
Marco Francone
Publikationsdatum: 01.09.2011
Verlag: Springer-Verlag
Erschienen in: Pediatric Radiology / Ausgabe 9/2011
Print ISSN: 0301-0449
Elektronische ISSN: 1432-1998
DOI: https://doi.org/10.1007/s00247-011-2141-0

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Adolescent Kawasaki disease: usefulness of 64-slice CT coronary angiography for follow-up investigation