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Erschienen in: Pediatric Radiology 2/2013

01.02.2013 | Minisymposium

Rickets: Part I

verfasst von: Richard M. Shore, Russell W. Chesney

Erschienen in: Pediatric Radiology | Ausgabe 2/2013

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Abstract

Rickets is characterized by impaired mineralization and ossification of the growth plates of growing children caused by a variety of disorders, the most frequent of which is nutritional deficiency of vitamin D. Despite ample knowledge of its etiology and the availability of cost-effective methods of preventing it, vitamin D deficiency rickets remains a significant problem in developing and developed countries. This two-part review covers the history, etiology, pathophysiology and clinical and radiographical findings of vitamin D deficiency rickets. Other less frequent causes of rickets and some of the disorders entering into the differential diagnoses of rickets are also considered. Controversial issues surrounding vitamin D deficiency include determination of what constitutes vitamin D sufficiency and the potential relationship between low levels of vitamin D metabolites in many individuals and unexplained fractures in infants.
Fußnoten
1
As is customary in the United States and Canada, 25D levels are expressed in ng/ml. However, there is a trend toward using nmol/l; 1 ng/ml = 2.5 nmol/l
 
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Metadaten
Titel
Rickets: Part I
verfasst von
Richard M. Shore
Russell W. Chesney
Publikationsdatum
01.02.2013
Verlag
Springer Berlin Heidelberg
Erschienen in
Pediatric Radiology / Ausgabe 2/2013
Print ISSN: 0301-0449
Elektronische ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-012-2532-x

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