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Skeletal Radiology

Erschienen in:

01.07.2005 | Scientific Article

¹⁸FDG-PET applications for cartilage neoplasms

verfasst von: Frieda Feldman, Ronald Van Heertum, Chitra Saxena, May Parisien

Erschienen in: Skeletal Radiology | Ausgabe 7/2005

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Abstract

Objective

To assess the value of [¹⁸F]fluoro-2-deoxy-d-glucose positron emission tomography (¹⁸FDG-PET) in defining aggressive cartilage neoplasms, particularly those with problematic or borderline histologic, imaging and clinical characteristics.

Design and patients

From 2000 to 2003, 29 cartilage lesions were studied with whole-body ¹⁸FDG-PET scans (Siemens Ecat Exact, Knoxville, Tenn.). Analyses of data in 20 females and nine males, 11–85 years old, were based on maximum standard uptake values (SUVs) in regions of interest (ROIs) on axial 3.37 mm thick, 3×3 pixel images. A statistically significant maximum SUV cutoff of 2.0 was used to distinguish benign from malignant cartilage neoplasms and correlated with the postoperative histopathologic findings.

Results

In 26 operated cases the overall sensitivity of whole-body ¹⁸FDG-PET in separating benign and malignant lesions was 90.9% (10/11), specificity 100% (18/18) and accuracy 96.6%.

Conclusions

Whole-body ¹⁸FDG-PET is a valuable adjunct in identifying primary, recurrent and metastatic cartilage malignancies. It supplements classic histology and morphologic imaging with functional data which may facilitate management in individual cases.

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Titel: 18FDG-PET applications for cartilage neoplasms
verfasst von: Frieda Feldman
Ronald Van Heertum
Chitra Saxena
May Parisien
Publikationsdatum: 01.07.2005
Verlag: Springer-Verlag
Erschienen in: Skeletal Radiology / Ausgabe 7/2005
Print ISSN: 0364-2348
Elektronische ISSN: 1432-2161
DOI: https://doi.org/10.1007/s00256-005-0894-y

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Springer Medizin

¹⁸FDG-PET applications for cartilage neoplasms

Abstract

Objective

Design and patients

Results

Conclusions

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Update Radiologie

Springer Medizin

Abstract

Objective

Design and patients

Results

Conclusions

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