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Seminars in Immunopathology

Erschienen in:

01.11.2009 | Review

Role of microglia in neuronal degeneration and regeneration

verfasst von: Lisa Walter, Harald Neumann

Erschienen in: Seminars in Immunopathology | Ausgabe 4/2009

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Abstract

Microglial cells, the resident macrophage population of the central nervous system (CNS), actively scan tissue under both normal and pathologic contexts. Their resulting engagement can become either neuroprotective or neurotoxic, leading to amelioration or aggravation of disease progression. In this review, we focus on the molecular signaling molecules involved in microglial responses and discuss observations demonstrating the diverse effects of microglia in animal models of CNS diseases.

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Titel: Role of microglia in neuronal degeneration and regeneration
verfasst von: Lisa Walter
Harald Neumann
Publikationsdatum: 01.11.2009
Verlag: Springer-Verlag
Erschienen in: Seminars in Immunopathology / Ausgabe 4/2009
Print ISSN: 1863-2297
Elektronische ISSN: 1863-2300
DOI: https://doi.org/10.1007/s00281-009-0180-5

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