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European Radiology

Erschienen in:

01.02.2006 | Cardiac

Left ventricular function studied with MDCT

verfasst von: Kai Uwe Juergens, Roman Fischbach

Erschienen in: European Radiology | Ausgabe 2/2006

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Abstract

Accurate determination of left ventricular (LV) myocardial function is fundamental for clinical diagnosis, risk stratification, and estimation of prognosis in patients with ischemic and nonischemic cardiomyopathy. Primarily, multi-detector-row spiral CT (MDCT) of the heart aimed at detecting coronary artery obstruction and cardiac morphology. Multiple studies have demonstrated that retrospectively, ECG-gated MDCT determination of LV volumes and consequently global LV function parameters is feasible in good agreement with established imaging modalities such as cineventriculography, echocardiography, and cine magnetic resonance imaging (CMR). Post-processing tools allow fast and semi-automatic determination of LV function parameters from MDCT data in analogy to known CMR evaluation approaches. Although MDCT is not considered to be first-line modality for LV function assessment, this technique provides accessory dynamic information in patients undergoing MDCT coronary angiography, contributing to combined assessment of cardiac morphology and function without need of additional radiation exposure. MDCT regional LV wall motion analysis at rest is feasible, but further improvement in temporal resolution seems mandatory to match results obtained from competing modalities. This paper will discuss the diagnostic potential of MDCT for assessment of LV function with regards to accuracy and clinical applications, as well as limitations, particularly in comparison with CMR as modality of reference.

Hammermeister KE, DeRouen TA, Dodge HT (1979) Variables predictive of survival in patients with coronary disease. Selection by univariate and multivariate analyses from the clinical, electrocardiographic, exercise, arteriographic, and quantitative angiographic evaluations. Circulation 59:421–430PubMed

White HD, Norris RM, Brown MA, Brandt PWT, Whitlock RML, Wild CJ (1987) Left ventricular end-systolic volume as the major determination of survival after recovery from myocardial infarction. Circulation 76:44–51PubMed

Shah PK, Maddahi J, Staniloff HM et al (1986) Variable spectrum and prognostic implications of left and right ventricular ejection fraction in patients with and without clinical heart failure after acute myocardial infarction. Am J Cardiol 58:387–393CrossRefPubMed

Schocken DD, Arrieta MI, Leaverton PE, Ross EA (1992) Prevalence and mortality rate of congestive heart failure in the United States. J Am Coll Cardiol 20:301–305PubMed

Gerber TC, Behrenbeck T, Allison T, Mullan BP, Rumberger JA, Gibbons RJ (1999) Comparison of measurement of left ventricular ejection fraction by Tc-99 m sestamibi first-pass angiography with electron beam computed tomography in patients with anterior wall acute myocardial infarction. Am J Cardiol 83:1022–1026CrossRefPubMed

Nieman K, Cademartiri F, Lemos PA, Raaijmakers R, Pattynama PM, de Feyter PJ (2002) Reliable noninvasive coronary angiography with fast submillimeter multislice spiral computed tomography. Circulation 106:2051–2054PubMed

Ropers D, Baum U, Pohle K et al (2003) Detection of coronary artery stenoses with thin-slice multi-detector row spiral computed tomography and multiplanar reconstruction. Circulation 107:664–666CrossRefPubMed

Hoffmann U, Moselewski F, Cury RC et al (2004) Predictive value of 16-slice multidetector spiral computed tomography to detect significant obstructive coronary artery disease in patients at high risk for coronary artery disease: patient-versus-segment-based analysis. Circulation 110:2638–2643CrossRefPubMed

Dewey M, Laule M, Krug L et al (2004) Multisegment and halfscan reconstruction of 16-slice computed tomography for detection of coronary artery stenoses. Invest Radiol 39:223–229CrossRefPubMed

10.

Hamoir XL, Flohr T, Hamoir V et al (2005) Coronary arteries: assessment of image quality and optimal reconstruction window in retrospective ECG-gated multislice CT at 375-ms gantry rotation time. Eur Radiol 15:296–304CrossRefPubMed

11.

Lorenz CH, Walker ES, Morgan VL, Klein SS, Graham Jr TP (1999) Normal human right and left ventricular mass, systolic function, and gender differences by Cine Magnetic Resonance Imaging. J Cardiol Magn Reson 1:7–21

12.

Sandstede J, Lipke C, Beer M et al (2000) Age- and gender-specific differences in left and right ventricular cardiac function and mass determined by cine magnetic resonance imaging. Eur Radiol 10:438–442CrossRefPubMed

13.

Alfakih K, Plein S, Thiele H, Jones T, Ridgway JP, Sivananthan MU (2003) Normal human left and right ventricular dimensions for MRI as assessed by turbo gradient echo and steady-state free precession imaging sequences. J Magn Reson Imaging 17:323–329CrossRefPubMed

14.

Setser RM, Fischer SE, Lorenz CH (2000) Quantification of left ventricular function with magnetic resonance images acquired in real time. J Magn Reson Imaging 12:430–438CrossRefPubMed

15.

Barkhausen J, Ruehm SG, Goyen M et al (2001) MR evaluation of ventricular function: true fast imaging with steady-state precession versus fast low-angle shot cine MR imaging: feasibility study. Radiology 219:264–269PubMed

16.

Thiele H, Nagel E, Paetsch I et al (2001) Functional cardiac MR imaging with steady-state free precession (SSFP) significantly improves endocardial border delineation without contrast agents. J Magn Reson Imaging 14:362–367CrossRefPubMed

17.

Messrroghli DR, Bainbridge GJ, Alfakih K et al (2005) Assessment of regional left ventricular function accuracy and reproducibility of positioning standard short-axis sections in cardiac MR imaging. Radiology 235:229–236PubMed

18.

Plein S, Smith WHT, Ridgway JP et al (2001) Qualitative and quantitative analysis of regional left ventricular wall dynamics using real-time magnetic resonance imaging: comparison with conventional breath-hold gradient echo acquisition in volunteers and patients. J Magn Reson Imaging 14:23–30CrossRefPubMed

19.

Spuentrup E, Schroeder J, Mahnken AH et al (2003) Quantitative assessment of left ventricular function with interactive real-time spiral and radial MR imaging. Radiology 227:870–876PubMed

20.

Kuhl HP, Spuentrup E, Wall A et al (2004) Assessment of myocardial function with interactive non-breath-hold real-time MR imaging: comparison with echocardiography and breath-hold Cine MR imaging. Radiology 231:198–207PubMed

21.

Kuijpers D, Janssen CHC, van Dijkman PRM, Oudkerk M (2004) Dobutamine stress MRI. Part 1. Safety and feasibility of dobutamine cardiovascular magnetic resonance in patients suspected of myocardial ischemia. Eur Radiol 14:1823–1828PubMed

22.

Kuijpers D, van Dijkman PRM, Janssen CHC, Vliegenhart R, Zijlstra F, Oudkerk M (2004) Dobutamine stress MRI. Part II. Risk stratification with dobutamine cardiovascular magnetic resonance in patients suspected of myocardial ischemia. Eur Radiol 14:2046–2052CrossRefPubMed

23.

Malm S, Frigstad S, Sagberg E, Larsson H, Skjaerpe T (2004) Accurate and reproducible measurement of left ventricular volume and ejection fraction by contrast echocardiography: a comparison with magnetic resonance imaging. J Am Coll Cardiol 44:1030–1035CrossRefPubMed

24.

Bavelaar-Croon CD, Kayser HW, van der Wall EE et al (2000) Left ventricular function: correlation of quantitative gated SPECT and MR imaging over a wide range of values. Radiology 217:572–575PubMed

25.

Manrique A, Faraggi M, Vera P et al (1999) TI-201 and Tc-99m MIBI gated SPECT in patients with large perfusion defects and left ventricular dysfunction: comparison with equilibrium radionuclide angiography. J Nucl Med 40:805–809PubMed

26.

Slart RHJA, Bax JJ, de Jong RM et al (2004) Comparison of gated PET with MRI for evaluation of left ventricular function in patients with coronary artery disease. J Nucl Med 45:176–182PubMed

27.

Lackner K, Thurn P (1981) Computed tomography of the heart: ECG-gated and continuous scans. Radiology 140:413–420PubMed

28.

Woodhouse CE, Janowitz WR, Viamonte M Jr (1997) Coronary arteries: retrospective cardiac gating technique to reduce cardiac motion artifact at spiral CT. Radiology 204:566–569PubMed

29.

Boyd DP, Lipton MJ (1983) Cardiac computed-tomography. Proc IEEE 71:298–307

30.

Woo P, Mao S, Wang S, Detrano RC (1997) Left ventricular size determined by electron beam computed tomography predicts significant coronary artery disease and events. Am J Cardiol 79:1236–1238CrossRefPubMed

31.

Cerqueira MD, Weissman NJ, Dilsizian V et al (2002) Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart. A statement for healthcare professionals from the Cardiac Imaging Committee of the Council on Clinical Cardiology of the American Heart Association. Circulation 105:539–542CrossRefPubMed

32.

Leitlinien der Deutschen Röntgengesellschaft (DRG) für den Einsatz der MR-Tomographie in der Herzdiagnostik. Fortschr Röntgenstr 2004:176:1185–1193

33.

Juergens KU, Schulze Eilfing B, DeAngelis G, Seifarth H, Heindel W, Fischbach R (2004) Anatomy and morphology of the heart based on multidetector-row computed tomography coronary angiography: morphometric analysis of 60 middle aged asymptomatic male individuals. Eur Radiol 14:R3

34.

Juergens KU, Grude M, Maintz D et al (2004) Multi-detector row CT of left ventricular function with dedicated analysis software versus MR imaging: initial experience. Radiology 230:403–410PubMed

35.

Garett JS, Lanzer P, Jaschke W et al (1985) Measurement of cardiac output by cine computed tomography. Am J Cardiol 56:657–661PubMed

36.

Ludman PF, Coats AJ, Poole-Wilson PA, Rees RS (1993) Measurement accuracy of cardiac output in humans: indicator dilution technique vs. geometric analysis by ultrafast computed tomography. J Am Coll Cardiol 21:1482–1489PubMed

37.

Mahnken AH, Klotz E, Hennemuth A et al (2003) Measurement of cardiac output from a test-bolus injection in multislice computed tomography. Eur Radiol 13:2498–2504CrossRefPubMed

38.

Mahnken AH, Henzler D, Klotz E et al (2004) Determination of cardiac output with multislice spiral computed tomography: a validation study. Invest Radiol 39:451–454CrossRefPubMed

39.

Boehm T, Alkadhi H, Roffi M et al (2004) Time-effectiveness, observer-dependence, and accuracy of measurements of left ventricular ejection fraction using 4-channel MDCT. Fortschr Röntgenstr 176:529–537

40.

Juergens KU, Seifarth H, Maintz D et al (2005) Left ventricular function determination with Multidetector-row CT of the heart: are short-axis image reformations necessary? Am J Roentgenol (in press)

41.

Koch K, Oellig F, Kunz P et al (2004) Assessment of global and regional left ventricular function with a 16-slice Spiral-CT using two different software tools for quantitative analysis and qualitative evaluation of wall motion changes in comparison with Magnetic Resonance Imaging. Fortschr Röntgenstr 176:1786–1793CrossRef

42.

Juergens KU, Grude M, Fallenberg EM et al (2002) Using ECG-gated multidetector CT to evaluate global left ventricular myocardial function in patients with coronary artery disease. Am J Roentgenol 179:1545–1550PubMed

43.

Heuschmid M, Küttner A, Schröder S et al (2003) Left ventricular functional parameters using ECG-gated multidetector spiral CT in comparison with invasive ventriculography. Fortschr Röntgenstr 175:1349–1354

44.

Hosoi S, Mochizuki T, Miyagawa M, Shen Y, Murase K, Ikezoe J (2003) Assessment of left ventricular volumes using multidetector row computed tomography (MDCT): phantom and human studies. Radiat Med 21:62–67PubMed

45.

Dirksen MS, Bax JJ, de Roos A et al (2002) Usefulness of dynamic multislice computed tomography of left ventricular function in unstable angina pectoris and comparison with echocardiography. Am J Cardiol 90:1157–1160CrossRefPubMed

46.

Dirksen MS, Jukema JW, Bax JJ et al (2005) Cardiac multidetector-row computed tomography in patients with instable angina. Am J Cardiol 95:457–461CrossRefPubMed

47.

Grude M, Juergens KU, Wichter T et al (2003) Evaluation of global left ventricular myocardial function with electrocardiogram-gated multidetector computed tomography: comparison with magnetic resonance imaging. Invest Radiol 38:653–661PubMed

48.

Ehrhard K, Oberholzer K, Gast K, Mildenberger P, Kreitner K-F, Thelen M (2002) Multi-slice CT (MSCT) in cardiac function imaging: threshold-value-supported 3D volume reconstructions to determine the left ventricular ejection fraction in comparison to MRI. Fortschr Röntgenstr 174:1566–1569CrossRef

49.

Mahnken AH, Spuentrup E, Niethammer M et al (2003) Quantitative and qualitative assessment of left ventricular volume with ECG-gated multislice Spiral CT: value of different image reconstruction algorithms in comparison to MRI. Acta Radiol 38:604–611

50.

Halliburton SS, Petersilka M, Schvartzman PR, Obuchowski N, White RD (2003) Evaluation of left ventricular dysfunction using multiphasic reconstructions of coronary multi-slice computed tomography data in patients with chronic ischemic heart disease: validation against cine magnetic resonance imaging. Int J Card Imaging 19:73–83CrossRef

51.

Mahnken AH, Spüntrup E, Wildberger JE et al (2003) Quantification of cardiac function with multislice spiral CT using retrospective ECG-gating: comparison with MRI. Fortschr Röntgenstr 175:83–88CrossRef

52.

Coche E, Belge B, Vlassenbroeck A et al (2004) Accurate assessment of left ventricular volumes and ejection fraction using retrospectively gated multislice cardiac CT: comparison with cine MRI. Eur Radiol 14:S2–S270CrossRef

53.

Juergens KU, Maintz D, Grude M et al (2005) Multi-detector row computed tomography of the heart: does a multi-segment reconstruction algorithm improve left ventricular volume measurements? Eur Radiol 15:111–117CrossRefPubMed

54.

Cui W, Kondo T, Anno T et al (2004) The accuracy and optimal slice thickness of multislice helical computed tomography for right and left ventricular volume measurement. Chin Med J 117:1283–1287PubMed

55.

Belge BM, Coche E, Vlassenbroek A, Van Beers B, Vanoverschelde J, Gerber BL (2004) Assessment of regional left ventricular wall thickness and wall thickening by retrospectively gated multi-detector row computed tomography: comparison with cine magnetic resonance imaging. Radiology 231:273 (P)

56.

Schuijf JD, Bax JJ, Salm LP et al (2005) Noninvasive coronary imaging and assessment of left ventricular function using 16-slice computed tomography. Am J Cardiol 95:571–574CrossRefPubMed

57.

Heuschmid M, Rothfuss J, Schröder S et al (2005) Left ventricular functional parameters: comparison of 16-slice spiral CT with MRI. Fortschr Röntgenstr 177:60–66CrossRef

58.

Yamamuro M, Tadamura E, Kubo S et al (2005) Cardiac functional analysis with multi-detector row CT and segmental reconstruction algorithm: comparison with echocardiography, SPECT, and MR imaging. Radiology 234:381–390PubMed

59.

Schlosser T, Pagonidis K, Herborn CU et al (2005) Assessment of left ventricular parameters using 16-MDCT and new software for endocardial and epicardial border delineation. Am J Roentgenol 184:765–773

60.

Mahnken AH, Koos R, Katoh M et al (2005) Sixteen-slice spiral CT versus MR imaging for the assessment of left ventricular function in acute myocardial infarction. Eur Radiol 714–720

61.

Schuijf JD, Bax JJ, Jukema JW et al (2004) Noninvasive angiography and assessment of left ventricular function using multislice computed tomography in patients with type 2 diabetes. Diabetes Care 27:2905–2910PubMed

62.

Schuijf JD, Bax JJ, Jukema JW et al (2005) Noninvasive evaluation of the coronary arteries with multislice computed tomography in hypertensive patients. Hypertension 45:1–6CrossRef

63.

Juergens KU, Ozgun M, Maintz D et al (2005) Analyse der globalen und regionalen linksventrikulären Funktion mittels 16-Zeilen-Spiral-Computertomographie des Herzens im Vergleich zur MR-Tomographie. Fortschr Röntgenstr 177:S273

64.

Paul J-F, Dambrin G, Caussin C, Lancelin B, Angel C (2003) Sixteen-slice computed tomography after acute myocardial infarction. From perfusion defect to the culprit lesion. Circulation 108:373–374CrossRefPubMed

65.

Gosalia A, Haramati LB, Sheth MP, Spindola-Franco H (2004) CT detection of acute myocardial infarction. Am J Roentgenol 182:1563–1566

66.

Koyama Y, Matsuoka H, Mochizuki T et al (2005) Assessment of reperfused acute myocardial infarction with two-phase contrast-enhanced helical CT: prediction of left ventricular function and wall thickness. Radiology 235:804–811PubMed

67.

Nikolaou K, Sanz J, Poon M et al (2005) Assessment of myocardial perfusion and viability from routine contrast-enhanced 16-detector-row computed tomography of the heart: preliminary results. Eur Radiol 15:864–871CrossRefPubMed

68.

Boese JM, Bahner ML, Albers J, van Kaick (2000) Optimization of temporal resolution in CT using retrospectively ECG-gating. Radiologe 40:123–129CrossRefPubMed

Titel: Left ventricular function studied with MDCT
verfasst von: Kai Uwe Juergens
Roman Fischbach
Publikationsdatum: 01.02.2006
Verlag: Springer-Verlag
Erschienen in: European Radiology / Ausgabe 2/2006
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-005-2888-5

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Springer Medizin

Left ventricular function studied with MDCT

Abstract

Neu im Fachgebiet Radiologie

Screening-Mammografie offenbart erhöhtes Herz-Kreislauf-Risiko

S3-Leitlinie zu Pankreaskrebs aktualisiert

Fünf Dinge, die im Kindernotfall besser zu unterlassen sind

„Nur wer sich gut aufgehoben fühlt, kann auch für Patientensicherheit sorgen“

Update Radiologie

Springer Medizin

Abstract

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