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Erschienen in: European Radiology 3/2010

01.03.2010 | Gastrointestinal

Determining gastric cancer resectability by dynamic MDCT

verfasst von: Zilai Pan, Huan Zhang, Chao Yan, Lianjun Du, Bei Ding, Qi Song, Huawei Ling, Baisong Huang, Kemin Chen

Erschienen in: European Radiology | Ausgabe 3/2010

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Abstract

Purpose

Multi-detector row CT (MDCT) has been widely used to detect primary lesions and to evaluate TNM staging. In this study we evaluated the accuracy of dynamic MDCT in the preoperative determination of the resectability of gastric cancer.

Methods

MDCT was used to image 350 cases of gastric cancer diagnosed by biopsy before surgery. MDCT findings regarding TNM staging and resectability were correlated with surgical and pathological findings.

Results

The accuracy of MDCT for staging gastric cancer was high, especially for tumour stage T1 (94.3%), lymph node stage N2 (87.3%), and for predicting distant metastases (>96.6%). When resectability was considered to be the outcome, the total accuracy of MDCT was 87.4%, sensitivity was 89.7% and specificity was 76.7%. Results showed high sensitivity for identifying peritoneal seeding (90.0%) and for predicting liver metastasis (80.0%).

Conclusion

Dynamic enhanced MDCT is useful for TNM staging of gastric cancers and for predicting tumour respectability preoperatively.
Literatur
1.
Zurück zum Zitat Rossi M, Broglia L, Maccioni F, Bezzi M, Laghi A, Graziano P et al (1997) Hydro-CT in patients with gastric cancer: preoperative radiology staging. Eur Radiol 7:659–664CrossRefPubMed Rossi M, Broglia L, Maccioni F, Bezzi M, Laghi A, Graziano P et al (1997) Hydro-CT in patients with gastric cancer: preoperative radiology staging. Eur Radiol 7:659–664CrossRefPubMed
2.
Zurück zum Zitat Takao M, Fukuda T (1998) Gastric cancer: evaluation of triphasic spiral CT and radiologic-pathologic correlation. J Comput Assist Tomogr 22:288–294CrossRefPubMed Takao M, Fukuda T (1998) Gastric cancer: evaluation of triphasic spiral CT and radiologic-pathologic correlation. J Comput Assist Tomogr 22:288–294CrossRefPubMed
3.
Zurück zum Zitat Yamada I, Saito N, Takeshita K, Yoshino N, Tetsumura A, Kumagai J, Shibuya H (2001) Early gastric carcinoma: evaluation with high-spatial-resolution MR Imaging in vitro. Radiology 220:115–121PubMed Yamada I, Saito N, Takeshita K, Yoshino N, Tetsumura A, Kumagai J, Shibuya H (2001) Early gastric carcinoma: evaluation with high-spatial-resolution MR Imaging in vitro. Radiology 220:115–121PubMed
4.
Zurück zum Zitat Horton KM, Fishman EK (2003) Current role of CT in imaging of the stomach. Radiographics 23:75–87CrossRefPubMed Horton KM, Fishman EK (2003) Current role of CT in imaging of the stomach. Radiographics 23:75–87CrossRefPubMed
5.
Zurück zum Zitat Tsuda K, Hori S, Murakami T, Nakamura H, Tomoda K, Nakanishi K, Shiozaki H (1995) Intramural invasion of gastric cancer: evaluation by CT with water-filling method. J Comput Assisted Tomogr 19:941–947CrossRef Tsuda K, Hori S, Murakami T, Nakamura H, Tomoda K, Nakanishi K, Shiozaki H (1995) Intramural invasion of gastric cancer: evaluation by CT with water-filling method. J Comput Assisted Tomogr 19:941–947CrossRef
6.
Zurück zum Zitat Kim HJ, Kim AY, Oh ST, Kim JS, Kim KW, Kim PN, Lee MG, Ha HK (2005) Gastric cancer staging at multi-detector row CT gastrography: comparison of transverse and volumetric CT scanning. Radiology 236:879–885CrossRefPubMed Kim HJ, Kim AY, Oh ST, Kim JS, Kim KW, Kim PN, Lee MG, Ha HK (2005) Gastric cancer staging at multi-detector row CT gastrography: comparison of transverse and volumetric CT scanning. Radiology 236:879–885CrossRefPubMed
7.
Zurück zum Zitat Chen CY, Hsu JS, Wu DC, Kang WY, Hsieh JS, Jaw TS, Wu MT, Liu GC (2007) Gastric cancer: preoperative local staging with 3D multi-detector row CT—correlation with surgical and histopathologic results. Radiology 242:472–482CrossRefPubMed Chen CY, Hsu JS, Wu DC, Kang WY, Hsieh JS, Jaw TS, Wu MT, Liu GC (2007) Gastric cancer: preoperative local staging with 3D multi-detector row CT—correlation with surgical and histopathologic results. Radiology 242:472–482CrossRefPubMed
8.
Zurück zum Zitat Bhandari S, Shim CS, Kim JH, Jung IS, Cho JY, Lee JS, Lee MS, Kim BS (2004) Usefulness of three-dimensional, multidetector row CT (virtual gastroscopy and multiplanar reconstruction) in the evaluation of gastric cancer: a comparison with conventional endoscopy, EUS, and histopathology. Gastrointest Endosc 59:619–626CrossRefPubMed Bhandari S, Shim CS, Kim JH, Jung IS, Cho JY, Lee JS, Lee MS, Kim BS (2004) Usefulness of three-dimensional, multidetector row CT (virtual gastroscopy and multiplanar reconstruction) in the evaluation of gastric cancer: a comparison with conventional endoscopy, EUS, and histopathology. Gastrointest Endosc 59:619–626CrossRefPubMed
9.
Zurück zum Zitat Shimizu K, Ito K, Matsunaga N, Shimizu A, Kawakami Y (2005) Diagnosis of gastric cancer with MDCT using the water-filling method and multiplanar reconstruction: CT-histologic correlation. AJR Am J Roentgenol 185:1152–1158CrossRefPubMed Shimizu K, Ito K, Matsunaga N, Shimizu A, Kawakami Y (2005) Diagnosis of gastric cancer with MDCT using the water-filling method and multiplanar reconstruction: CT-histologic correlation. AJR Am J Roentgenol 185:1152–1158CrossRefPubMed
10.
Zurück zum Zitat Shinohara T, Ohyama S, Yamaguchi T, Muto T, Kohno A, Kato Y, Urashima M (2005) Clinical value of multidetector row computed tomography in detecting lymph node metastasis of early gastric cancer. Eur J Surg Oncol 31:743–748CrossRefPubMed Shinohara T, Ohyama S, Yamaguchi T, Muto T, Kohno A, Kato Y, Urashima M (2005) Clinical value of multidetector row computed tomography in detecting lymph node metastasis of early gastric cancer. Eur J Surg Oncol 31:743–748CrossRefPubMed
11.
Zurück zum Zitat Habermann CR, Weiss F, Riecken R, Honarpisheh H, Bohnacker S, Staedtler C, Dieckmann C, Schoder V, Adam G (2004) Preoperative staging of gastric adenocarcinoma: comparison of helical CT and endoscopic US. Radiology 230:465–471CrossRefPubMed Habermann CR, Weiss F, Riecken R, Honarpisheh H, Bohnacker S, Staedtler C, Dieckmann C, Schoder V, Adam G (2004) Preoperative staging of gastric adenocarcinoma: comparison of helical CT and endoscopic US. Radiology 230:465–471CrossRefPubMed
12.
Zurück zum Zitat D’Elia F, Zingarelli A, Palli D, Grani M (2000) Hydro-dynamic CT preoperative staging of gastric cancer: correlation with pathological findings. A prospective study of 107 cases. Eur Radiol 10:1877–1885CrossRefPubMed D’Elia F, Zingarelli A, Palli D, Grani M (2000) Hydro-dynamic CT preoperative staging of gastric cancer: correlation with pathological findings. A prospective study of 107 cases. Eur Radiol 10:1877–1885CrossRefPubMed
13.
Zurück zum Zitat Japanese Research Society for Gastric Carcinoma (1995) Japanese classification of gastric carcinoma, 1st English edn. Kanehara, Tokyo Japanese Research Society for Gastric Carcinoma (1995) Japanese classification of gastric carcinoma, 1st English edn. Kanehara, Tokyo
14.
Zurück zum Zitat Fukuya T, Honda H, Kaneko K, Kuroiwa T, Yoshimitsu K, Irie H, Maehara Y, Masuda K (1997) Efficacy of helical CT in T-staging of gastric cancer. J Comput Assist Tomogr 21:73–81CrossRefPubMed Fukuya T, Honda H, Kaneko K, Kuroiwa T, Yoshimitsu K, Irie H, Maehara Y, Masuda K (1997) Efficacy of helical CT in T-staging of gastric cancer. J Comput Assist Tomogr 21:73–81CrossRefPubMed
15.
Zurück zum Zitat Düx M, Richter GM, Hansmann J, Kuntz C, Kauffmann GW (1999) Helical hydro-CT for diagnosis and staging of gastric carcinoma. J Comput Assist Tomogr 23:913–922CrossRefPubMed Düx M, Richter GM, Hansmann J, Kuntz C, Kauffmann GW (1999) Helical hydro-CT for diagnosis and staging of gastric carcinoma. J Comput Assist Tomogr 23:913–922CrossRefPubMed
16.
Zurück zum Zitat Dorfman RE, Alpern MB, Gross BH, Sandler MA (1991) Upper abdominal lymph nodes: criteria for normal size determined with CT. Radiology 180:319–322PubMed Dorfman RE, Alpern MB, Gross BH, Sandler MA (1991) Upper abdominal lymph nodes: criteria for normal size determined with CT. Radiology 180:319–322PubMed
17.
Zurück zum Zitat Magnusson A, Anderson T (1989) Contrast enhancement of pathologic lymph nodes demonstrated by computed tomography. Acta Radiol 30:307–301CrossRefPubMed Magnusson A, Anderson T (1989) Contrast enhancement of pathologic lymph nodes demonstrated by computed tomography. Acta Radiol 30:307–301CrossRefPubMed
18.
Zurück zum Zitat Fukuya T, Honda H, Hayashi T, Kaneko K, Tateshi Y, Ro T, Maehara Y, Tanaka M, Tsuneyoshi M, Masuda K (1995) Lymph-node metastases: efficacy for detection with helical CT in patients with gastric cancer. Radiology 197:705–711PubMed Fukuya T, Honda H, Hayashi T, Kaneko K, Tateshi Y, Ro T, Maehara Y, Tanaka M, Tsuneyoshi M, Masuda K (1995) Lymph-node metastases: efficacy for detection with helical CT in patients with gastric cancer. Radiology 197:705–711PubMed
19.
Zurück zum Zitat Zhu ZQ (2001) Choice of appropriate surgical method increase the quality of life for patient with early-stage gastric cancer [in Chinese]. Zhonghua Wei Chang Wai Ke Za Zhi 2:72–73 Zhu ZQ (2001) Choice of appropriate surgical method increase the quality of life for patient with early-stage gastric cancer [in Chinese]. Zhonghua Wei Chang Wai Ke Za Zhi 2:72–73
20.
Zurück zum Zitat Yin HR, Zhu ZQ, Lin YZ (2000) Surgical multimodality treatment in the treatment of advanced gastric cancer [in Chinese]. J Surg Concepts Pract 5:134–135 Yin HR, Zhu ZQ, Lin YZ (2000) Surgical multimodality treatment in the treatment of advanced gastric cancer [in Chinese]. J Surg Concepts Pract 5:134–135
21.
Zurück zum Zitat Kwee RM, Kwee TC (2007) Imaging in local staging of gastric cancer: a systematic review. J Clin Oncol 25:2107–2116CrossRefPubMed Kwee RM, Kwee TC (2007) Imaging in local staging of gastric cancer: a systematic review. J Clin Oncol 25:2107–2116CrossRefPubMed
22.
Zurück zum Zitat Kumano S, Murakami T, Kim T, Hori M, Iannaccone R, Nakata S, Onishi H, Osuga K, Tomoda K, Catalano C, Nakamura H (2005) T staging of gastric cancer: role of multi-detector row CT. Radiology 237(3):961–966CrossRefPubMed Kumano S, Murakami T, Kim T, Hori M, Iannaccone R, Nakata S, Onishi H, Osuga K, Tomoda K, Catalano C, Nakamura H (2005) T staging of gastric cancer: role of multi-detector row CT. Radiology 237(3):961–966CrossRefPubMed
23.
Zurück zum Zitat Yang DM, Kim HC, Jin W, Ryu CW, Kang JH, Park CH, Kim HS, Jung DH (2007) 64 multidetector-row computed tomography for preoperative evaluation of gastric cancer: histological correlation. J Comput Assist Tomogr 31:98–103CrossRefPubMed Yang DM, Kim HC, Jin W, Ryu CW, Kang JH, Park CH, Kim HS, Jung DH (2007) 64 multidetector-row computed tomography for preoperative evaluation of gastric cancer: histological correlation. J Comput Assist Tomogr 31:98–103CrossRefPubMed
Metadaten
Titel
Determining gastric cancer resectability by dynamic MDCT
verfasst von
Zilai Pan
Huan Zhang
Chao Yan
Lianjun Du
Bei Ding
Qi Song
Huawei Ling
Baisong Huang
Kemin Chen
Publikationsdatum
01.03.2010
Verlag
Springer-Verlag
Erschienen in
European Radiology / Ausgabe 3/2010
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-009-1576-2

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