Skip to main content
Erschienen in: European Radiology 4/2010

01.04.2010 | Urogenital

Interactive dedicated training curriculum improves accuracy in the interpretation of MR imaging of prostate cancer

verfasst von: Oguz Akin, Christopher C. Riedl, Nicole M. Ishill, Chaya S. Moskowitz, Jingbo Zhang, Hedvig Hricak

Erschienen in: European Radiology | Ausgabe 4/2010

Einloggen, um Zugang zu erhalten

Abstract

Objective

To assess the effect of interactive dedicated training on radiology fellows’ accuracy in assessing prostate cancer on MRI.

Methods

Eleven radiology fellows, blinded to clinical and pathological data, independently interpreted preoperative prostate MRI studies, scoring the likelihood of tumour in the peripheral and transition zones and extracapsular extension. Each fellow interpreted 15 studies before dedicated training (to supply baseline interpretation accuracy) and 200 studies (10/week) after attending didactic lectures. Expert radiologists led weekly interactive tutorials comparing fellows’ interpretations to pathological tumour maps. To assess interpretation accuracy, receiver operating characteristic (ROC) analysis was conducted, using pathological findings as the reference standard.

Results

In identifying peripheral zone tumour, fellows’ average area under the ROC curve (AUC) increased from 0.52 to 0.66 (after didactic lectures; p < 0.0001) and remained at 0.66 (end of training; p < 0.0001); in the transition zone, their average AUC increased from 0.49 to 0.64 (after didactic lectures; p = 0.01) and to 0.68 (end of training; p = 0.001). In detecting extracapsular extension, their average AUC increased from 0.50 to 0.67 (after didactic lectures; p = 0.003) and to 0.81 (end of training; p < 0.0001).

Conclusion

Interactive dedicated training significantly improved accuracy in tumour localization and especially in detecting extracapsular extension on prostate MRI.
Literatur
1.
Zurück zum Zitat Fuchsjäger M, Shukla-Dave A, Akin O, Barentsz J, Hricak H (2008) Prostate cancer imaging. Acta Radiol 49:107–120CrossRefPubMed Fuchsjäger M, Shukla-Dave A, Akin O, Barentsz J, Hricak H (2008) Prostate cancer imaging. Acta Radiol 49:107–120CrossRefPubMed
2.
3.
Zurück zum Zitat Claus FG, Hricak H, Hattery RR (2004) Pretreatment evaluation of prostate cancer: role of MR imaging and 1H MR spectroscopy. Radiographics 24:S167–180CrossRefPubMed Claus FG, Hricak H, Hattery RR (2004) Pretreatment evaluation of prostate cancer: role of MR imaging and 1H MR spectroscopy. Radiographics 24:S167–180CrossRefPubMed
4.
Zurück zum Zitat Rifkin MD, Zerhouni EA, Gatsonis CA, Quint LE, Paushter DM, Epstein JI, Hamper U, Walsh PC, McNeil BJ (1990) Comparison of magnetic resonance imaging and ultrasonography in staging early prostate cancer. Results of a multi-institutional cooperative trial. N Engl J Med 323:621–626PubMed Rifkin MD, Zerhouni EA, Gatsonis CA, Quint LE, Paushter DM, Epstein JI, Hamper U, Walsh PC, McNeil BJ (1990) Comparison of magnetic resonance imaging and ultrasonography in staging early prostate cancer. Results of a multi-institutional cooperative trial. N Engl J Med 323:621–626PubMed
5.
Zurück zum Zitat Schiebler ML, Yankaskas BC, Tempany C, Spritzer CE, Rifkin MD, Pollack HM, Holtz P, Zerhouni EA (1992) MR imaging in adenocarcinoma of the prostate: interobserver variation and efficacy for determining stage C disease. AJR Am J Roentgenol 158:559–562PubMed Schiebler ML, Yankaskas BC, Tempany C, Spritzer CE, Rifkin MD, Pollack HM, Holtz P, Zerhouni EA (1992) MR imaging in adenocarcinoma of the prostate: interobserver variation and efficacy for determining stage C disease. AJR Am J Roentgenol 158:559–562PubMed
6.
Zurück zum Zitat Tempany CM, Zhou X, Zerhouni EA, Rifkin MD, Quint LE, Piccoli CW, Ellis JH, McNeil BJ (1994) Staging of prostate cancer: results of Radiology Diagnostic Oncology Group project comparison of three MR imaging techniques. Radiology 192:47–54PubMed Tempany CM, Zhou X, Zerhouni EA, Rifkin MD, Quint LE, Piccoli CW, Ellis JH, McNeil BJ (1994) Staging of prostate cancer: results of Radiology Diagnostic Oncology Group project comparison of three MR imaging techniques. Radiology 192:47–54PubMed
7.
Zurück zum Zitat Yu KK, Hricak H, Alagappan R, Chernoff DM, Bacchetti P, Zaloudek CJ (1997) Detection of extracapsular extension of prostate carcinoma with endorectal and phased-array coil MR imaging: multivariate feature analysis. Radiology 202:697–702PubMed Yu KK, Hricak H, Alagappan R, Chernoff DM, Bacchetti P, Zaloudek CJ (1997) Detection of extracapsular extension of prostate carcinoma with endorectal and phased-array coil MR imaging: multivariate feature analysis. Radiology 202:697–702PubMed
8.
Zurück zum Zitat Mullerad M, Hricak H, Wang L, Chen HN, Kattan MW, Scardino PT (2004) Prostate cancer: detection of extracapsular extension by genitourinary and general body radiologists at MR imaging. Radiology 232:140–146CrossRefPubMed Mullerad M, Hricak H, Wang L, Chen HN, Kattan MW, Scardino PT (2004) Prostate cancer: detection of extracapsular extension by genitourinary and general body radiologists at MR imaging. Radiology 232:140–146CrossRefPubMed
9.
Zurück zum Zitat Hom JJ, Coakley FV, Simko JP, Qayyum A, Lu Y, Schmitt L, Carroll PR, Kurhanewicz J (2006) Prostate cancer: endorectal MR imaging and MR spectroscopic imaging—distinction of true-positive results from chance-detected lesions. Radiology 238:192–199CrossRefPubMed Hom JJ, Coakley FV, Simko JP, Qayyum A, Lu Y, Schmitt L, Carroll PR, Kurhanewicz J (2006) Prostate cancer: endorectal MR imaging and MR spectroscopic imaging—distinction of true-positive results from chance-detected lesions. Radiology 238:192–199CrossRefPubMed
10.
Zurück zum Zitat Obuchowski NA (1997) Nonparametric analysis of clustered ROC curve data. Biometrics 53:567–578CrossRefPubMed Obuchowski NA (1997) Nonparametric analysis of clustered ROC curve data. Biometrics 53:567–578CrossRefPubMed
11.
Zurück zum Zitat Akin O, Sala E, Moskowitz CS, Kuroiwa K, Ishill NM, Pucar D, Scardino PT, Hricak H (2006) Transition zone prostate cancers: features, detection, localization, and staging at endorectal MR imaging. Radiology 239:784–792CrossRefPubMed Akin O, Sala E, Moskowitz CS, Kuroiwa K, Ishill NM, Pucar D, Scardino PT, Hricak H (2006) Transition zone prostate cancers: features, detection, localization, and staging at endorectal MR imaging. Radiology 239:784–792CrossRefPubMed
12.
Zurück zum Zitat Li H, Sugimura K, Kaji Y, Kitamura Y, Fujii M, Hara I, Tachibana M (2006) Conventional MRI capabilities in the diagnosis of prostate cancer in the transition zone. AJR Am J Roentgenol 186:729–742CrossRefPubMed Li H, Sugimura K, Kaji Y, Kitamura Y, Fujii M, Hara I, Tachibana M (2006) Conventional MRI capabilities in the diagnosis of prostate cancer in the transition zone. AJR Am J Roentgenol 186:729–742CrossRefPubMed
13.
Zurück zum Zitat Futterer JJ, Engelbrecht MR, Huisman HJ, Jager GJ, Hulsbergen-van De Kaa CA, Witjes JA, Barentsz JO (2005) Staging prostate cancer with dynamic contrast-enhanced endorectal MR imaging prior to radical prostatectomy: experienced versus less experienced readers. Radiology 237:541–549CrossRefPubMed Futterer JJ, Engelbrecht MR, Huisman HJ, Jager GJ, Hulsbergen-van De Kaa CA, Witjes JA, Barentsz JO (2005) Staging prostate cancer with dynamic contrast-enhanced endorectal MR imaging prior to radical prostatectomy: experienced versus less experienced readers. Radiology 237:541–549CrossRefPubMed
15.
Zurück zum Zitat Sickles EA, Wolverton DE, Dee KE (2002) Performance parameters for screening and diagnostic mammography: specialist and general radiologists. Radiology 224:861–869CrossRefPubMed Sickles EA, Wolverton DE, Dee KE (2002) Performance parameters for screening and diagnostic mammography: specialist and general radiologists. Radiology 224:861–869CrossRefPubMed
16.
Zurück zum Zitat Kan L, Olivotto IA, Warren Burhenne LJ, Sickles EA, Coleman AJ (2000) Standardized abnormal interpretation and cancer detection ratios to assess reading volume and reader performance in a breast screening program. Radiology 215:563–567PubMed Kan L, Olivotto IA, Warren Burhenne LJ, Sickles EA, Coleman AJ (2000) Standardized abnormal interpretation and cancer detection ratios to assess reading volume and reader performance in a breast screening program. Radiology 215:563–567PubMed
17.
Zurück zum Zitat Linver MN, Paster SB, Rosenberg RD, Key CR, Stidley CA, King WV (1992) Improvement in mammography interpretation skills in a community radiology practice after dedicated teaching courses: 2-year medical audit of 38,633 cases. Radiology 184:39–43PubMed Linver MN, Paster SB, Rosenberg RD, Key CR, Stidley CA, King WV (1992) Improvement in mammography interpretation skills in a community radiology practice after dedicated teaching courses: 2-year medical audit of 38,633 cases. Radiology 184:39–43PubMed
18.
Zurück zum Zitat European Society of Gastrointestinal and Abdominal Radiology CT Colonography Group Investigators (2007) Effect of directed training on reader performance for CT colonography: multicenter study. Radiology 242:152–161CrossRef European Society of Gastrointestinal and Abdominal Radiology CT Colonography Group Investigators (2007) Effect of directed training on reader performance for CT colonography: multicenter study. Radiology 242:152–161CrossRef
19.
Zurück zum Zitat Sala E, Akin O, Moskowitz CS, Eisenberg HF, Kuroiwa K, Ishill NM, Rajashanker B, Scardino PT, Hricak H (2006) Endorectal MR imaging in the evaluation of seminal vesicle invasion: diagnostic accuracy and multivariate feature analysis. Radiology 238:929–937CrossRefPubMed Sala E, Akin O, Moskowitz CS, Eisenberg HF, Kuroiwa K, Ishill NM, Rajashanker B, Scardino PT, Hricak H (2006) Endorectal MR imaging in the evaluation of seminal vesicle invasion: diagnostic accuracy and multivariate feature analysis. Radiology 238:929–937CrossRefPubMed
20.
Zurück zum Zitat Wang L, Mullerad M, Chen HN, Eberhardt SC, Kattan MW, Scardino PT, Hricak H (2004) Prostate cancer: incremental value of endorectal MR imaging findings for prediction of extracapsular extension. Radiology 232:133–139CrossRefPubMed Wang L, Mullerad M, Chen HN, Eberhardt SC, Kattan MW, Scardino PT, Hricak H (2004) Prostate cancer: incremental value of endorectal MR imaging findings for prediction of extracapsular extension. Radiology 232:133–139CrossRefPubMed
21.
Zurück zum Zitat Girouin N, Mège-Lechevallier F, Tonina Senes A, Bissery A, Rabilloud M, Maréchal JM, Colombel M, Lyonnet D, Rouvière O (2007) Prostate dynamic contrast-enhanced MRI with simple visual diagnostic criteria: is it reasonable? Eur Radiol 17:1498–1509CrossRefPubMed Girouin N, Mège-Lechevallier F, Tonina Senes A, Bissery A, Rabilloud M, Maréchal JM, Colombel M, Lyonnet D, Rouvière O (2007) Prostate dynamic contrast-enhanced MRI with simple visual diagnostic criteria: is it reasonable? Eur Radiol 17:1498–1509CrossRefPubMed
22.
Zurück zum Zitat Mazaheri Y, Shukla-Dave A, Hricak H, Fine SW, Zhang J, Inurrigarro G, Moskowitz CS, Ishill NM, Reuter VE, Touijer K, Zakian KL, Koutcher JA (2008) Prostate cancer: identification with combined diffusion-weighted MR imaging and 3D 1H MR spectroscopic imaging—correlation with pathologic findings. Radiology 246:480–488CrossRefPubMed Mazaheri Y, Shukla-Dave A, Hricak H, Fine SW, Zhang J, Inurrigarro G, Moskowitz CS, Ishill NM, Reuter VE, Touijer K, Zakian KL, Koutcher JA (2008) Prostate cancer: identification with combined diffusion-weighted MR imaging and 3D 1H MR spectroscopic imaging—correlation with pathologic findings. Radiology 246:480–488CrossRefPubMed
23.
Zurück zum Zitat Lemaitre L, Puech P, Poncelet E, Bouyé S, Leroy X, Biserte J, Villers A (2009) Dynamic contrast-enhanced MRI of anterior prostate cancer: morphometric assessment and correlation with radical prostatectomy findings. Eur Radiol 19:470–480CrossRefPubMed Lemaitre L, Puech P, Poncelet E, Bouyé S, Leroy X, Biserte J, Villers A (2009) Dynamic contrast-enhanced MRI of anterior prostate cancer: morphometric assessment and correlation with radical prostatectomy findings. Eur Radiol 19:470–480CrossRefPubMed
24.
Zurück zum Zitat Fuchsjäger M, Akin O, Shukla-Dave A, Pucar D, Hricak H (2009) The role of MRI and MRSI in diagnosis, treatment selection, and post-treatment follow-up for prostate cancer. Clin Adv Hematol Oncol 7:193–202PubMed Fuchsjäger M, Akin O, Shukla-Dave A, Pucar D, Hricak H (2009) The role of MRI and MRSI in diagnosis, treatment selection, and post-treatment follow-up for prostate cancer. Clin Adv Hematol Oncol 7:193–202PubMed
25.
Zurück zum Zitat Mueller-Lisse U, Mueller-Lisse U, Scheidler J, Klein G, Reiser M (2005) Reproducibility of image interpretation in MRI of the prostate: application of the sextant framework by two different radiologists. Eur Radiol 15:1826–1833CrossRefPubMed Mueller-Lisse U, Mueller-Lisse U, Scheidler J, Klein G, Reiser M (2005) Reproducibility of image interpretation in MRI of the prostate: application of the sextant framework by two different radiologists. Eur Radiol 15:1826–1833CrossRefPubMed
26.
Zurück zum Zitat Kohn LT, Corrigan JM, Donaldson MS (2000) To err is human: building a safer health system. National Academy, Washington, DC Kohn LT, Corrigan JM, Donaldson MS (2000) To err is human: building a safer health system. National Academy, Washington, DC
27.
Zurück zum Zitat Sibley JC, Sackett DL, Neufeld V, Gerrard B, Rudnick KV, Fraser W (1982) A randomized trial of continuing medical education. N Engl J Med 306:511–555PubMedCrossRef Sibley JC, Sackett DL, Neufeld V, Gerrard B, Rudnick KV, Fraser W (1982) A randomized trial of continuing medical education. N Engl J Med 306:511–555PubMedCrossRef
28.
Zurück zum Zitat Davis D, O’Brien MA, Freemantle N, Wolf FM, Mazmanian P, Taylor-Vaisey A (1999) Impact of formal continuing medical education: do conferences, workshops, rounds, and other traditional continuing education activities change physician behavior or health care outcomes? JAMA 282:867–874CrossRefPubMed Davis D, O’Brien MA, Freemantle N, Wolf FM, Mazmanian P, Taylor-Vaisey A (1999) Impact of formal continuing medical education: do conferences, workshops, rounds, and other traditional continuing education activities change physician behavior or health care outcomes? JAMA 282:867–874CrossRefPubMed
29.
Zurück zum Zitat Chan S, Gunderman RB (2005) Emerging strategic themes for guiding change in academic radiology departments. Radiology 236:430–440CrossRefPubMed Chan S, Gunderman RB (2005) Emerging strategic themes for guiding change in academic radiology departments. Radiology 236:430–440CrossRefPubMed
Metadaten
Titel
Interactive dedicated training curriculum improves accuracy in the interpretation of MR imaging of prostate cancer
verfasst von
Oguz Akin
Christopher C. Riedl
Nicole M. Ishill
Chaya S. Moskowitz
Jingbo Zhang
Hedvig Hricak
Publikationsdatum
01.04.2010
Verlag
Springer-Verlag
Erschienen in
European Radiology / Ausgabe 4/2010
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-009-1625-x

Weitere Artikel der Ausgabe 4/2010

European Radiology 4/2010 Zur Ausgabe

Screening-Mammografie offenbart erhöhtes Herz-Kreislauf-Risiko

26.04.2024 Mammografie Nachrichten

Routinemäßige Mammografien helfen, Brustkrebs frühzeitig zu erkennen. Anhand der Röntgenuntersuchung lassen sich aber auch kardiovaskuläre Risikopatientinnen identifizieren. Als zuverlässiger Anhaltspunkt gilt die Verkalkung der Brustarterien.

S3-Leitlinie zu Pankreaskrebs aktualisiert

23.04.2024 Pankreaskarzinom Nachrichten

Die Empfehlungen zur Therapie des Pankreaskarzinoms wurden um zwei Off-Label-Anwendungen erweitert. Und auch im Bereich der Früherkennung gibt es Aktualisierungen.

Fünf Dinge, die im Kindernotfall besser zu unterlassen sind

18.04.2024 Pädiatrische Notfallmedizin Nachrichten

Im Choosing-Wisely-Programm, das für die deutsche Initiative „Klug entscheiden“ Pate gestanden hat, sind erstmals Empfehlungen zum Umgang mit Notfällen von Kindern erschienen. Fünf Dinge gilt es demnach zu vermeiden.

„Nur wer sich gut aufgehoben fühlt, kann auch für Patientensicherheit sorgen“

13.04.2024 Klinik aktuell Kongressbericht

Die Teilnehmer eines Forums beim DGIM-Kongress waren sich einig: Fehler in der Medizin sind häufig in ungeeigneten Prozessen und mangelnder Kommunikation begründet. Gespräche mit Patienten und im Team können helfen.

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.