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11.09.2017 | Cardiac

Differences in myocardial strain between pectus excavatum patients and healthy subjects assessed by cardiac MRI: a pilot study

verfasst von: André Lollert, Tilman Emrich, Jakob Eichstädt, Christoph Kampmann, Tariq Abu-Tair, Salmai Turial, Christoph Düber, Karl-Friedrich Kreitner, Gundula Staatz

Erschienen in: European Radiology | Ausgabe 3/2018

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Abstract

Objectives

To evaluate differences in myocardial strain between pectus excavatum (PE) patients and healthy subjects (HS) assessed by cardiac MRI using the feature-tracking algorithm.

Methods

Cardiac MRI was performed in 14 PE patients and 14 HS (9:5 male to female in each group; age 11–30 years) using a 3T scanner. Post-examination analysis included manual biventricular contouring with volumetry and ejection fraction measurement by two independent radiologists. Dedicated software was used for automated strain assessment.

Results

In five of the PE patients, the right ventricular ejection fraction was slightly impaired (40–44 %). PE patients had a significantly higher left ventricular longitudinal strain (P=0.004), mid (P=0.035) and apical (P=0.001) circumferential strain as well as apical circumferential strain rate (P=0.001), mid right ventricular circumferential strain (P=0.008) and strain rate (P=0.035), and apical right ventricular circumferential strain (P=0.012) and strain rate (P=0.044) than HS. The right ventricular longitudinal strain and strain rate did not differ significantly between PE patients and HS.

Conclusions

Myocardial strain differs significantly between PE patients and HS. Higher myocardial strain in the mid and apical ventricles of PE patients indicates a compensation mechanism to enhance ventricular output against basal sternal compression.

Key Points

• The right ventricle is frequently affected by the pectus excavatum deformity.

• Cardiac MRI revealed differences in myocardial strain in pectus excavatum patients.

• Pectus excavatum patients exhibited higher strain in the mid/apical ventricles.

• A compensation mechanism to enhance ventricular output against sternal compression is possible.

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Titel: Differences in myocardial strain between pectus excavatum patients and healthy subjects assessed by cardiac MRI: a pilot study
verfasst von: André Lollert
Tilman Emrich
Jakob Eichstädt
Christoph Kampmann
Tariq Abu-Tair
Salmai Turial
Christoph Düber
Karl-Friedrich Kreitner
Gundula Staatz
Publikationsdatum: 11.09.2017
Verlag: Springer Berlin Heidelberg
Erschienen in: European Radiology / Ausgabe 3/2018
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-017-5042-2

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Differences in myocardial strain between pectus excavatum patients and healthy subjects assessed by cardiac MRI: a pilot study