nach oben

Erschienen in:

01.03.2012 | Case Report

Visceral leishmaniasis in a patient with AIDS: early pathological diagnosis using conventional histology, PCR and electron microscopy is the key for adequate treatment

verfasst von: Albrecht Stenzinger, Johannes Nemeth, Frederick Klauschen, Christiane Schewe, Axel-Michael Ladhoff, Alexander Muckenhuber, Mariana Schürmann, Dirk Schürmann, Wilko Weichert

Erschienen in: Virchows Archiv | Ausgabe 3/2012

Einloggen, um Zugang zu erhalten

Excerpt

Leishmaniasis is a disease caused by protozoa that are transmitted by female sand flies (Phlebotomus) from either animals to humans (zoonosis) or from humans to humans (anthroponosis). Currently, approximately 30 sand fly species and 21 different Leishmania species are known, which reside as promastigotes in the gut of the arthropod. Once being inoculated via the skin and internalized in host macrophages and dendritic cells, the promastigotes transform to amastigotes and eventually disseminate via the lymph and blood system [1]. …

Nur mit Berechtigung zugänglich

Alvar J, Cañavate C, Gutiérrez-Solar B, Jiménez M, Laguna F, López-Vélez R, Molina R, Moreno J (1997) Leishmania and human immunodeficiency virus coinfection: the first 10 years. Clin Microbiol Rev 10:298–319PubMed

Alvar J, Aparicio P, Aseffa A, Den Boer M, Cañavate C, Dedet JP, Gradoni L, Ter Horst R, López-Vélez R, Moreno J (2008) The relationship between leishmaniasis and AIDS: the second 10 years. Clin Microbiol Rev 21:334–359PubMedCrossRef

Chappuis F, Sundar S, Hailu A, Ghalib H, Rijal S, Peeling RW, Alvar J, Boelaert M (2007) Visceral leishmaniasis: what are the needs for diagnosis, treatment and control? Nat Rev Microbiol 5:873–882PubMedCrossRef

Lasky T, Miko TL, Negesse Y, Solbach W, Röllinghoff M, Frommel D (1995) Detection of cutaneous Leishmania infection in paraffin-embedded skin biopsies using the polymerase chain reaction. Trans Royal Soc Trop Med Hyg 89:273–275CrossRef

Rogers MR, Popper SJ, Wirth DF (1990) Amplification of kinetoplast DNA as a tool in the detection and diagnosis of Leishmania. Exp Parasitol 71:267–275CrossRef

Costa JM, Durnand R, Denieu M, Rivollett D, Izri M, Houin R, Vidaud M, Bretagne S (1996) PCR-linked immunosorbent assay for diagnosis of Leishmaniasis in human immunodeficiency virus-infected patients. J Clin Microbiol 34:1831–1833PubMed

Laguna F, García-Samaniego J, Soriano V, Valencia E, Redondo C, Alonso MJ, González-Lahoz JM (1994) Gastrointestinal leishmaniasis in human immunodeficiency virus-infected patients: report of five cases and review. Clin Infect Dis 19:48–53PubMedCrossRef

Rosenthal E, Marty P, del Giudice P, Pradier C, Ceppi C, Gastaut JA, Le Fichoux Y, Cassuto JP (2000) HIV and Leishmania coinfection: a review of 91 cases with focus on atypical locations of Leishmania. Clin Infect Dis 31:1093–1095PubMedCrossRef

van Griensven J, Balasegaram M, Meheus F, Alvar J, Lynen L, Boelaert M (2010) Combination therapy for visceral leishmaniasis. Lancet Infect Dis 10:184–194PubMedCrossRef

10.

Schönian G, Nasereddin A, Dinse N, Schweynoch C, Schallig HD, Presber W, Jaffe CL (2003) PCR diagnosis and characterization of Leishmania in local and imported clinical samples. Diagn Microbiol Infect Dis 47:349–358PubMedCrossRef

Titel: Visceral leishmaniasis in a patient with AIDS: early pathological diagnosis using conventional histology, PCR and electron microscopy is the key for adequate treatment
verfasst von: Albrecht Stenzinger
Johannes Nemeth
Frederick Klauschen
Christiane Schewe
Axel-Michael Ladhoff
Alexander Muckenhuber
Mariana Schürmann
Dirk Schürmann
Wilko Weichert
Publikationsdatum: 01.03.2012
Verlag: Springer-Verlag
Erschienen in: Virchows Archiv / Ausgabe 3/2012
Print ISSN: 0945-6317
Elektronische ISSN: 1432-2307
DOI: https://doi.org/10.1007/s00428-012-1207-1

Neu im Fachgebiet Pathologie

01.04.2024 | Forensische Traumatologie | CME

Springer Medizin

Visceral leishmaniasis in a patient with AIDS: early pathological diagnosis using conventional histology, PCR and electron microscopy is the key for adequate treatment

Excerpt

Neu im Fachgebiet Pathologie

Theoretische Grundlagen von Explosionen und Explosionsverletzungen

Auswirkungen vorgeschalteter Laborprozesse auf die Digitalisierung histologischer Schnittpräparate

Knochenmarkhistologie bei Zytopenien

Herausforderungen der Automation bei der quantitativen Auswertung von Leberbiopsien

Springer Medizin

Excerpt

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 3/2012

Phenotyping of pulmonary carcinoids and a Ki-67-based grading approach

Sudden cardiac death caused by coronary vasculitis

Urothelial carcinoma of the renal pelvis with simultaneous trophoblastic and malignant clear cell endodermal-type differentiation

Dedifferentiated peripheral chondrosarcoma: a clinicopathologic, immunohistochemical, and molecular analysis of four cases

Histological and clinical characteristics of malignant giant cell tumor of bone

Aspects of liver pathology in adult patients with MDR3/ABCB4 gene mutations

Neu im Fachgebiet Pathologie

Theoretische Grundlagen von Explosionen und Explosionsverletzungen

Auswirkungen vorgeschalteter Laborprozesse auf die Digitalisierung histologischer Schnittpräparate

Knochenmarkhistologie bei Zytopenien

Herausforderungen der Automation bei der quantitativen Auswertung von Leberbiopsien