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Erschienen in: Surgical Endoscopy 6/2009

01.06.2009

Male sexual and urinary function after laparoscopic total mesorectal excision

verfasst von: Mario Morino, Umberto Parini, Marco Ettore Allaix, Gabriella Monasterolo, Riccardo Brachet Contul, Corrado Garrone

Erschienen in: Surgical Endoscopy | Ausgabe 6/2009

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Abstract

Background

Urinary and sexual dysfunction are potential complications of rectal surgery for cancer. This study retrospectively evaluated the frequency of such complications after laparoscopic total mesorectal excision (LTME) with autonomic nerve preservation.

Methods

For this study, 50 men younger than 75 years who underwent radical LTME for mid and low rectal cancer were followed up for at least 12 months, interviewed, and administered a standardized questionnaire about postoperative functional outcomes and quality of life.

Results

Sexual desire was maintained by 55.6%, ability to engage in intercourse by 57.8%, and ability to achieve orgasm and ejaculation by 37.8% of the patients. Distance of the tumor from the anal verge and adjuvant or neoadjuvant treatments were the significant predictors of poor postoperative sexual function. Seven patients (14%) presented transitory postoperative urinary dysfunction, all of whom were medically treated. Tumor stage and distance from the anal verge were independently associated with the postoperative global International Prostatic Symptom Score (IPSS). No differences were observed in urinary quality of life.

Conclusions

In this series, LTME did not reproduce or improve on sexual and urinary dysfunction outcomes obtained in the best open TME series. Further trials are needed to evaluate functional outcome in rectal cancer patients.
Literatur
1.
Zurück zum Zitat Morino M, Parini U, Giraudo G, Salval M, Brachet Contul R, Garrone C (2003) Laparoscopic total mesorectal excision: a consecutive series of 100 patients. Ann Surg 237:335–342PubMedCrossRef Morino M, Parini U, Giraudo G, Salval M, Brachet Contul R, Garrone C (2003) Laparoscopic total mesorectal excision: a consecutive series of 100 patients. Ann Surg 237:335–342PubMedCrossRef
2.
Zurück zum Zitat Morino M, Allaix ME, Giraudo G, Corno F, Garrone C (2005) Laparoscopic versus open surgery for extraperitoneal rectal cancer: a prospective comparative study. Surg Endosc 19:1460–1467PubMedCrossRef Morino M, Allaix ME, Giraudo G, Corno F, Garrone C (2005) Laparoscopic versus open surgery for extraperitoneal rectal cancer: a prospective comparative study. Surg Endosc 19:1460–1467PubMedCrossRef
3.
Zurück zum Zitat Bretagnol F, Rullier E, Couderc P, Rullier A, Saric J (2003) Technical and oncological feasibility of laparoscopic total mesorectal excision with pouch coloanal anastomosis for rectal cancer. Colorectal Dis 5:451–453PubMedCrossRef Bretagnol F, Rullier E, Couderc P, Rullier A, Saric J (2003) Technical and oncological feasibility of laparoscopic total mesorectal excision with pouch coloanal anastomosis for rectal cancer. Colorectal Dis 5:451–453PubMedCrossRef
4.
Zurück zum Zitat Leroy J, Jamali F, Forbes L, Smith M, Rubino F, Mutter D, Marescaux J (2004) Laparoscopic total mesorectal excision (TME) for rectal cancer surgery: long-term outcomes. Surg Endosc 18:281–289PubMedCrossRef Leroy J, Jamali F, Forbes L, Smith M, Rubino F, Mutter D, Marescaux J (2004) Laparoscopic total mesorectal excision (TME) for rectal cancer surgery: long-term outcomes. Surg Endosc 18:281–289PubMedCrossRef
5.
Zurück zum Zitat Tsang WW, Chung CC, Kwok SY, Li MK (2006) Laparoscopic sphincter-preserving total mesorectal excision with colonic J-pouch reconstruction: five-year results. Ann Surg 243:353–358PubMedCrossRef Tsang WW, Chung CC, Kwok SY, Li MK (2006) Laparoscopic sphincter-preserving total mesorectal excision with colonic J-pouch reconstruction: five-year results. Ann Surg 243:353–358PubMedCrossRef
6.
Zurück zum Zitat Aziz O, Constantinides V, Tekkis PP, Athanasiou T, Purkayastha S, Paraskeva P, Darzi AW, Heriot AG (2006) Laparoscopic versus open surgery for rectal cancer: a meta-analysis. Ann Surg Oncol 13:413–424PubMedCrossRef Aziz O, Constantinides V, Tekkis PP, Athanasiou T, Purkayastha S, Paraskeva P, Darzi AW, Heriot AG (2006) Laparoscopic versus open surgery for rectal cancer: a meta-analysis. Ann Surg Oncol 13:413–424PubMedCrossRef
7.
Zurück zum Zitat Marescaux J, Rubino F, Leroy J (2005) Laparoscopic total mesorectal excision for rectal cancer surgery (review). Dig Dis 23:135–141PubMedCrossRef Marescaux J, Rubino F, Leroy J (2005) Laparoscopic total mesorectal excision for rectal cancer surgery (review). Dig Dis 23:135–141PubMedCrossRef
8.
Zurück zum Zitat Rullier E, Sa Cunha A, Couderc P, Rullier A, Gontier R, Saric J (2003) Laparoscopic intersphinteric resection with coloplasty and coloanal anastomosis for mid and low rectal cancer. Br J Surg 90:445–451PubMedCrossRef Rullier E, Sa Cunha A, Couderc P, Rullier A, Gontier R, Saric J (2003) Laparoscopic intersphinteric resection with coloplasty and coloanal anastomosis for mid and low rectal cancer. Br J Surg 90:445–451PubMedCrossRef
9.
Zurück zum Zitat Mundy AR (1982) An anatomical explanation for bladder dysfunction following rectal and uterine surgery. Br J Urol 54:501–504PubMedCrossRef Mundy AR (1982) An anatomical explanation for bladder dysfunction following rectal and uterine surgery. Br J Urol 54:501–504PubMedCrossRef
10.
Zurück zum Zitat Sugihara K, Moriya Y, Akasu T, Fujita S (1996) Pelvic autonomic nerve preservation for patients with rectal carcinoma: oncologic and functional outcome. Cancer 78:1871–1880PubMedCrossRef Sugihara K, Moriya Y, Akasu T, Fujita S (1996) Pelvic autonomic nerve preservation for patients with rectal carcinoma: oncologic and functional outcome. Cancer 78:1871–1880PubMedCrossRef
11.
Zurück zum Zitat Lindsey I, Mortensen NJ (2002) Iatrogenic impotence and rectal dissection. Br J Surg 89:1493–1494PubMedCrossRef Lindsey I, Mortensen NJ (2002) Iatrogenic impotence and rectal dissection. Br J Surg 89:1493–1494PubMedCrossRef
12.
Zurück zum Zitat Quah HM, Jayne DG, Eu KW, Seow-Choen F (2002) Bladder and sexual dysfunction following laparoscopically assisted and conventional open mesorectal resection for cancer. Br J Surg 89:1551–1556PubMedCrossRef Quah HM, Jayne DG, Eu KW, Seow-Choen F (2002) Bladder and sexual dysfunction following laparoscopically assisted and conventional open mesorectal resection for cancer. Br J Surg 89:1551–1556PubMedCrossRef
13.
Zurück zum Zitat Jayne DG, Brown JM, Thorpe H, Walker J, Quirke P, Guillou PJ (2005) Bladder and sexual function following resection for rectal cancer in a randomized clinical trial of laparoscopic versus open technique. Br J Surg 92:1124–1132PubMedCrossRef Jayne DG, Brown JM, Thorpe H, Walker J, Quirke P, Guillou PJ (2005) Bladder and sexual function following resection for rectal cancer in a randomized clinical trial of laparoscopic versus open technique. Br J Surg 92:1124–1132PubMedCrossRef
14.
Zurück zum Zitat Carlsen E, Schlichting E, Guldvog I, Johnson E, Heald RJ (1998) Effect of the introduction of total mesorectal excision for the treatment of rectal cancer. Br J Surg 85:526–529PubMedCrossRef Carlsen E, Schlichting E, Guldvog I, Johnson E, Heald RJ (1998) Effect of the introduction of total mesorectal excision for the treatment of rectal cancer. Br J Surg 85:526–529PubMedCrossRef
15.
Zurück zum Zitat Heald RJ, Moran BJ, Ryall RDH, Sexton R, MacFarlane JKI (1998) The Basingstoke experience of total mesorectal excision, 1978–1997. Arch Surg 133:894–899PubMedCrossRef Heald RJ, Moran BJ, Ryall RDH, Sexton R, MacFarlane JKI (1998) The Basingstoke experience of total mesorectal excision, 1978–1997. Arch Surg 133:894–899PubMedCrossRef
16.
Zurück zum Zitat Buess G, Hutterer F, Theiss R, Bobel M, Isselhard W, Pichmaier H (1984) Das System fur die Transanale Endoskopische Rektum-operation. Chirurgie 55:677 Buess G, Hutterer F, Theiss R, Bobel M, Isselhard W, Pichmaier H (1984) Das System fur die Transanale Endoskopische Rektum-operation. Chirurgie 55:677
17.
Zurück zum Zitat Denis L, Griffiths K, Khoury S (1998) Measuring the symptom and health impact of benign prostatic hyperplasia and its treatment. In: Denis L, Griffiths K, Khoury S et al (eds) 4th international consultation on benign prostatic hyperplasia. World Health Organization, Health Publication Ltd, Paris, pp 265–280 Denis L, Griffiths K, Khoury S (1998) Measuring the symptom and health impact of benign prostatic hyperplasia and its treatment. In: Denis L, Griffiths K, Khoury S et al (eds) 4th international consultation on benign prostatic hyperplasia. World Health Organization, Health Publication Ltd, Paris, pp 265–280
18.
Zurück zum Zitat Rosen RC, Riley A, Wagner G, Osterloh IH, Kirkpatrick J, Mishra A (1997) The International Index of Erectile Function (IIEF): a multidimensional scale for assessment of erectile dysfunction. Urology 49:822–830PubMedCrossRef Rosen RC, Riley A, Wagner G, Osterloh IH, Kirkpatrick J, Mishra A (1997) The International Index of Erectile Function (IIEF): a multidimensional scale for assessment of erectile dysfunction. Urology 49:822–830PubMedCrossRef
19.
Zurück zum Zitat Hendren SK, O’Connor BI, Liu M, Asano T, Cohen Z, Swallow CJ, Macrae HM, Gryfe R, McLeod RS (2005) Prevalence of male and female sexual dysfunction is high following surgery for rectal cancer. Ann Surg 242:212–223PubMedCrossRef Hendren SK, O’Connor BI, Liu M, Asano T, Cohen Z, Swallow CJ, Macrae HM, Gryfe R, McLeod RS (2005) Prevalence of male and female sexual dysfunction is high following surgery for rectal cancer. Ann Surg 242:212–223PubMedCrossRef
20.
Zurück zum Zitat Enker WE (1992) Potency, cure, and local control in the operative treatment of rectal cancer. Arch Surg 127:1396–1401; discussion 1402PubMed Enker WE (1992) Potency, cure, and local control in the operative treatment of rectal cancer. Arch Surg 127:1396–1401; discussion 1402PubMed
21.
Zurück zum Zitat Havenga K, Enker WE, McDermott K, Cohen AM, Minsky BD, Guillem J (1996) Male and female sexual and urinary function after total mesorectal excision with autonomic nerve preservation for carcinoma of the rectum. J Am Coll Surg 182:495–502PubMed Havenga K, Enker WE, McDermott K, Cohen AM, Minsky BD, Guillem J (1996) Male and female sexual and urinary function after total mesorectal excision with autonomic nerve preservation for carcinoma of the rectum. J Am Coll Surg 182:495–502PubMed
22.
Zurück zum Zitat Maas CP, Moriya Y, Steup WH, Kiebert GM, Kranenbarg WM, van de Velde CJ (1998) Radical and nerve-preserving surgery for rectal cancer in The Netherlands: a prospective study on morbidity and functional outcome. Br J Surg 85:92–97PubMedCrossRef Maas CP, Moriya Y, Steup WH, Kiebert GM, Kranenbarg WM, van de Velde CJ (1998) Radical and nerve-preserving surgery for rectal cancer in The Netherlands: a prospective study on morbidity and functional outcome. Br J Surg 85:92–97PubMedCrossRef
23.
Zurück zum Zitat Birgisson H, Påhlman L, Gunnarsson U, Glimelius B (2005) Adverse effects of preoperative radiation therapy for rectal cancer: long-term follow-up of the Swedish Rectal Cancer Trial. J Clin Oncol 23:8697–8705PubMedCrossRef Birgisson H, Påhlman L, Gunnarsson U, Glimelius B (2005) Adverse effects of preoperative radiation therapy for rectal cancer: long-term follow-up of the Swedish Rectal Cancer Trial. J Clin Oncol 23:8697–8705PubMedCrossRef
24.
Zurück zum Zitat Srinivasaiah N, Joseph B, Mackey P, Monson JRT (2008) How do we manage early rectal cancer? A national questionnaire survey among members of the ACPGBI after the preliminary results of the MRC CR07/NCIC CO16 randomized trial. Colorectal Dis 10:357–362PubMedCrossRef Srinivasaiah N, Joseph B, Mackey P, Monson JRT (2008) How do we manage early rectal cancer? A national questionnaire survey among members of the ACPGBI after the preliminary results of the MRC CR07/NCIC CO16 randomized trial. Colorectal Dis 10:357–362PubMedCrossRef
25.
Zurück zum Zitat Chorost MI, Weber TK, Lee RJ, Rodriguez-Bigas MA, Petrelli NJ (2000) Sexual dysfunction, informed consent and multimodality therapy for rectal cancer. Am J Surg 179:271–274PubMedCrossRef Chorost MI, Weber TK, Lee RJ, Rodriguez-Bigas MA, Petrelli NJ (2000) Sexual dysfunction, informed consent and multimodality therapy for rectal cancer. Am J Surg 179:271–274PubMedCrossRef
26.
Zurück zum Zitat Nesbakken A, Nygaard K, Bull-Njaa T, Carlsen E, Eri LM (2000) Bladder and sexual dysfunction after mesorectal excision for rectal cancer. Br J Surg 87:206–210PubMedCrossRef Nesbakken A, Nygaard K, Bull-Njaa T, Carlsen E, Eri LM (2000) Bladder and sexual dysfunction after mesorectal excision for rectal cancer. Br J Surg 87:206–210PubMedCrossRef
27.
Zurück zum Zitat Lesurtel M, Fritsch S, Sellam R, Molinier N, Mosnier H (2004) Does laparoscopic colorectal resection for diverticular disease impair male urinary and sexual function? Surg Endosc 18:1774–1777PubMedCrossRef Lesurtel M, Fritsch S, Sellam R, Molinier N, Mosnier H (2004) Does laparoscopic colorectal resection for diverticular disease impair male urinary and sexual function? Surg Endosc 18:1774–1777PubMedCrossRef
28.
Zurück zum Zitat Leveckis J, Boucher NR, Parys BT, Reed MW, Shorthouse AJ, Anderson JB (1995) Bladder and erectile dysfunction before and after rectal surgery for cancer. Br J Urol 76:752–756PubMed Leveckis J, Boucher NR, Parys BT, Reed MW, Shorthouse AJ, Anderson JB (1995) Bladder and erectile dysfunction before and after rectal surgery for cancer. Br J Urol 76:752–756PubMed
29.
Zurück zum Zitat Saito N, Sarashima H, Nunomura M, Koda K, Takiguchi N, Nakajima N (1998) Clinical evaluation of nerve-sparing surgery combined with preoperative radiotherapy in advanced rectal cancer patients. Am J Surg 175:277–282PubMedCrossRef Saito N, Sarashima H, Nunomura M, Koda K, Takiguchi N, Nakajima N (1998) Clinical evaluation of nerve-sparing surgery combined with preoperative radiotherapy in advanced rectal cancer patients. Am J Surg 175:277–282PubMedCrossRef
30.
Zurück zum Zitat Nagawa H, Muto T, Sunouchi K, Higuchi Y, Tsurita G, Watanabe T, Sawada T (2001) Randomized, controlled trial of lateral node dissection vs nerve-preserving resection in patients with rectal cancer after preoperative radiotherapy. Dis Colon Rectum 44:1274–1280PubMedCrossRef Nagawa H, Muto T, Sunouchi K, Higuchi Y, Tsurita G, Watanabe T, Sawada T (2001) Randomized, controlled trial of lateral node dissection vs nerve-preserving resection in patients with rectal cancer after preoperative radiotherapy. Dis Colon Rectum 44:1274–1280PubMedCrossRef
31.
Zurück zum Zitat Maurer CA, Z’Graggen K, Renzulli P, Schilling MK, Netzer P, Buchler MW (2001) Total mesorectal excision preserves male genital function compared with conventional rectal cancer surgery. Br J Surg 88:1501–1505PubMedCrossRef Maurer CA, Z’Graggen K, Renzulli P, Schilling MK, Netzer P, Buchler MW (2001) Total mesorectal excision preserves male genital function compared with conventional rectal cancer surgery. Br J Surg 88:1501–1505PubMedCrossRef
32.
Zurück zum Zitat Pocard M, Zinzindohoue F, Haab F, Caplin S, Parc R, Tiret E (2002) A prospective study of sexual and urinary function before and after total mesorectal excision with autonomic nerve preservation for rectal cancer. Surgery 131:368–372PubMedCrossRef Pocard M, Zinzindohoue F, Haab F, Caplin S, Parc R, Tiret E (2002) A prospective study of sexual and urinary function before and after total mesorectal excision with autonomic nerve preservation for rectal cancer. Surgery 131:368–372PubMedCrossRef
33.
Zurück zum Zitat Kim NK, Aahn TW, Park JK, Lee KY, Lee WH, Sohn SK, Min JS (2002) Assessment of sexual and voiding function after total mesorectal excision with pelvic autonomic nerve preservation in males with rectal cancer. Dis Colon Rectum 45:1178–1185PubMedCrossRef Kim NK, Aahn TW, Park JK, Lee KY, Lee WH, Sohn SK, Min JS (2002) Assessment of sexual and voiding function after total mesorectal excision with pelvic autonomic nerve preservation in males with rectal cancer. Dis Colon Rectum 45:1178–1185PubMedCrossRef
Metadaten
Titel
Male sexual and urinary function after laparoscopic total mesorectal excision
verfasst von
Mario Morino
Umberto Parini
Marco Ettore Allaix
Gabriella Monasterolo
Riccardo Brachet Contul
Corrado Garrone
Publikationsdatum
01.06.2009
Verlag
Springer-Verlag
Erschienen in
Surgical Endoscopy / Ausgabe 6/2009
Print ISSN: 0930-2794
Elektronische ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-008-0136-1

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