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Pediatric Nephrology
Erschienen in: Pediatric Nephrology 10/2010

01.10.2010 | Educational Review

Glomerulocystic kidney disease

verfasst von: John J. Bissler, Brian J. Siroky, Hong Yin

Erschienen in: Pediatric Nephrology | Ausgabe 10/2010

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Abstract

Glomerulocystic disease is a rare renal cystic disease with a long descriptive history. Findings from recent studies have significantly advanced the pathophysiological understanding of the disease processes leading to this peculiar phenotype. Many genetic syndromes associated with glomerulocystic disease have had their respective proteins localized to primary cilia or centrosomes. Transcriptional control of renal developmental pathways is dysregulated in obstructive diseases that also lead to glomerulocystic disease, emphasizing the importance of transcriptional choreography between renal development and renal cystic disease.
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Metadaten
Titel
Glomerulocystic kidney disease
verfasst von
John J. Bissler
Brian J. Siroky
Hong Yin
Publikationsdatum
01.10.2010
Verlag
Springer-Verlag
Erschienen in
Pediatric Nephrology / Ausgabe 10/2010
Print ISSN: 0931-041X
Elektronische ISSN: 1432-198X
DOI
https://doi.org/10.1007/s00467-009-1416-2

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