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Pediatric Nephrology

Erschienen in:

17.09.2015 | Review

Kidney donation after circulatory death: current evidence and opportunities for pediatric recipients

verfasst von: Matko Marlais, Chris Callaghan, Stephen D. Marks

Erschienen in: Pediatric Nephrology | Ausgabe 7/2016

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Abstract

Organ donation after circulatory death (DCD) has experienced a revival worldwide over the past 20 years, and is now widely practiced for kidney transplantation. Some previous concerns about these organs such as the high incidence of delayed graft function have been alleviated through evidence from adult studies. There are now a number of large adult cohorts reporting favorable 5-year outcomes for DCD kidney transplants, comparable to kidneys donated after brain death (DBD). This has resulted in a marked increase in the use of DCD kidneys for adult recipients in some countries and an increase in the overall number of kidney transplants. In contrast, the uptake of DCD kidneys for pediatric recipients is still low and concerns still exist over the longer-term outcomes of DCD organs. In view of the data from adult practice and the poor outcomes for children who stay on dialysis, DCD kidney transplantation should be offered as an option for children on the kidney transplant waiting list.

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Titel: Kidney donation after circulatory death: current evidence and opportunities for pediatric recipients
verfasst von: Matko Marlais
Chris Callaghan
Stephen D. Marks
Publikationsdatum: 17.09.2015
Verlag: Springer Berlin Heidelberg
Erschienen in: Pediatric Nephrology / Ausgabe 7/2016
Print ISSN: 0931-041X
Elektronische ISSN: 1432-198X
DOI: https://doi.org/10.1007/s00467-015-3175-6

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