Skip to main content
Erschienen in: Acta Neurochirurgica 8/2014

01.08.2014 | Clinical Article - Functional

Long-term seizure outcome after stereotactic amygdalohippocampectomy

verfasst von: Zdeněk Vojtěch, Hana Malíková, Lenka Krámská, Jiří Anýž, Martin Syrůček, Josef Zámečník, Roman Liščák, Vilibald Vladyka

Erschienen in: Acta Neurochirurgica | Ausgabe 8/2014

Einloggen, um Zugang zu erhalten

Abstract

Background

The aim of the study was to evaluate the long-term seizure outcome and complications after stereotactic radiofrequency amygdalohippocampectomy (SAHE) performed for mesial temporal lobe epilepsy (MTLE).

Methods

The article describes the cases of 61 patients who were treated at our institution during the period 2004–2010. Mean post-operative follow-up was 5.3 years.

Results

At the last postsurgical visit, 43 (70.5 %) patients were Engel Class I, six (9.8 %) Class II, nine (14.8 %) Class III and three (4.9 %) Class IV. The surgery was complicated by four intracranial haematomas. One of them caused acute hydrocephalus and was treated by shunting and resolved without sequelae. After SAHE, we performed open epilepsy surgery and re-thermo lesions in three and two patients, respectively (8.2 %). There were two cases of meningitis which required antibiotic treatment. In six patients psychiatric disorders developed and one of these committed suicide due to postoperative depression.

Conclusions

Our results provide preliminary evidence for good long-term seizure outcomes after SAHE. SAHE could be an alternative therapy for MTLE.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Zurück zum Zitat Behrens E, Schramm J, Zentner J, König R (1997) Surgical and neurological complications in a series of 708 epilepsy surgery procedures. Neurosurgery 41:1–10PubMedCrossRef Behrens E, Schramm J, Zentner J, König R (1997) Surgical and neurological complications in a series of 708 epilepsy surgery procedures. Neurosurgery 41:1–10PubMedCrossRef
2.
Zurück zum Zitat Blume WT, Parrent AG, Kaibara M (1997) Stereotactic amygdalohippocampectomy and mesial temporal spikes. Epilepsia 38:930–936PubMedCrossRef Blume WT, Parrent AG, Kaibara M (1997) Stereotactic amygdalohippocampectomy and mesial temporal spikes. Epilepsia 38:930–936PubMedCrossRef
3.
Zurück zum Zitat Brierley B, Medford N, Shaw P, David AS (2004) Emotional memory and perception in temporal lobectomy patients with amygdala damage. J Neurol Neurosurg Psychiatry 75:593–599PubMedCentralPubMedCrossRef Brierley B, Medford N, Shaw P, David AS (2004) Emotional memory and perception in temporal lobectomy patients with amygdala damage. J Neurol Neurosurg Psychiatry 75:593–599PubMedCentralPubMedCrossRef
5.
Zurück zum Zitat Cleary RA, Baxendale SA, Thompson PJ, Foong J (2013) Predicting and preventing psychopathology following temporal lobe epilepsy surgery. Epilepsy Behav 26:322–234PubMedCrossRef Cleary RA, Baxendale SA, Thompson PJ, Foong J (2013) Predicting and preventing psychopathology following temporal lobe epilepsy surgery. Epilepsy Behav 26:322–234PubMedCrossRef
6.
Zurück zum Zitat Davies KG, Risse GL, Gates JR (2005) Naming ability after tailored left temporal resection with extraoperative language mapping: increased risk of decline with later epilepsy onset age. Epilepsy Behav 7:273–278PubMedCrossRef Davies KG, Risse GL, Gates JR (2005) Naming ability after tailored left temporal resection with extraoperative language mapping: increased risk of decline with later epilepsy onset age. Epilepsy Behav 7:273–278PubMedCrossRef
7.
Zurück zum Zitat Egan RA, Shults WT, So N, Burchiel K, Kellogg JX, Salinsky M (2000) Visual field deficits in conventional anterior temporal lobectomy versus amygdalohippocampectomy. Neurology 55:1818–1822PubMedCrossRef Egan RA, Shults WT, So N, Burchiel K, Kellogg JX, Salinsky M (2000) Visual field deficits in conventional anterior temporal lobectomy versus amygdalohippocampectomy. Neurology 55:1818–1822PubMedCrossRef
8.
Zurück zum Zitat Engel J Jr (2011) Another good reason to consider surgical treatment for epilepsy more often and sooner. Arch Neurol 68:707–708PubMedCrossRef Engel J Jr (2011) Another good reason to consider surgical treatment for epilepsy more often and sooner. Arch Neurol 68:707–708PubMedCrossRef
9.
Zurück zum Zitat Engel J Jr, Van Ness PC, Rassmussen TB, Ojemann LM (1993) Outcome with respect to epileptic seizures. In: Engel J Jr (ed) Surgical treatment of the epilepsies. Raven, New York, pp 609–621 Engel J Jr, Van Ness PC, Rassmussen TB, Ojemann LM (1993) Outcome with respect to epileptic seizures. In: Engel J Jr (ed) Surgical treatment of the epilepsies. Raven, New York, pp 609–621
10.
Zurück zum Zitat Engel J Jr, Wiebe S, French J, Sperling M, Williamson P, Spencer D, Gumnit R, Zahn C, Westbrook E, Enos B (2003) Practice parameter: temporal lobe and localized neocortical resections for epilepsy. Epilepsia 44:741–751PubMedCrossRef Engel J Jr, Wiebe S, French J, Sperling M, Williamson P, Spencer D, Gumnit R, Zahn C, Westbrook E, Enos B (2003) Practice parameter: temporal lobe and localized neocortical resections for epilepsy. Epilepsia 44:741–751PubMedCrossRef
11.
Zurück zum Zitat Georgiadis I, Kapsalaki EZ, Fountas KN (2013) Temporal Lobe Resective Surgery for Medically Intractable Epilepsy: A Review of Complications and Side Effects. Epilepsy Res Treat:752195. Georgiadis I, Kapsalaki EZ, Fountas KN (2013) Temporal Lobe Resective Surgery for Medically Intractable Epilepsy: A Review of Complications and Side Effects. Epilepsy Res Treat:752195.
12.
Zurück zum Zitat Gonzalez-Martinez J, Vadera S, Mullin J, Enatsu R, Alexopoulos A, Patwardhan R, Bingaman W, Najm I (2014) Robot-Assisted Stereotactic Laser Ablation in Medically Intractable Epilepsy: Operative Technique. Neurosurgery Jan 19. [Epub ahead of print] PMID:24448180. Gonzalez-Martinez J, Vadera S, Mullin J, Enatsu R, Alexopoulos A, Patwardhan R, Bingaman W, Najm I (2014) Robot-Assisted Stereotactic Laser Ablation in Medically Intractable Epilepsy: Operative Technique. Neurosurgery Jan 19. [Epub ahead of print] PMID:24448180.
13.
Zurück zum Zitat Guénot M, Isnard J, Catenoix H, Mauguière F, Sindou M (2011) SEEG-guided RF-thermocoagulation of epileptic foci: a therapeutic alternative for drug-resistant non-operable partial epilepsies. Adv Tech Stand Neurosurg 36:61–78PubMed Guénot M, Isnard J, Catenoix H, Mauguière F, Sindou M (2011) SEEG-guided RF-thermocoagulation of epileptic foci: a therapeutic alternative for drug-resistant non-operable partial epilepsies. Adv Tech Stand Neurosurg 36:61–78PubMed
14.
Zurück zum Zitat Helmstaedter C, Petzold I, Bien CG (2011) The cognitive consequence of resecting nonlesional tissues in epilepsy surgery—results from MRI- and histopathology-negative patients with temporal lobe epilepsy. Epilepsia 52:1402–1408PubMedCrossRef Helmstaedter C, Petzold I, Bien CG (2011) The cognitive consequence of resecting nonlesional tissues in epilepsy surgery—results from MRI- and histopathology-negative patients with temporal lobe epilepsy. Epilepsia 52:1402–1408PubMedCrossRef
15.
Zurück zum Zitat Josephson CB, Pohlmann-Eden B (2012) The “natural” history of medically treated temporal lobe epilepsy: what can an evidence-based approach tell us? Epilepsy Res Treat 2012:216510PubMedCentralPubMed Josephson CB, Pohlmann-Eden B (2012) The “natural” history of medically treated temporal lobe epilepsy: what can an evidence-based approach tell us? Epilepsy Res Treat 2012:216510PubMedCentralPubMed
16.
Zurück zum Zitat Kuzniecky RI, Jackson GD (1995) Temporal lobe epilepsy. In: Kuzniecky RI, Jackson GD (eds) Magnetic resonance in epilepsy. Raven Press, New York, pp 107–182 Kuzniecky RI, Jackson GD (1995) Temporal lobe epilepsy. In: Kuzniecky RI, Jackson GD (eds) Magnetic resonance in epilepsy. Raven Press, New York, pp 107–182
17.
Zurück zum Zitat Kwan P, Brodie MJ (2000) Early identification of refractory epilepsy. N Engl J Med 342:314–319PubMedCrossRef Kwan P, Brodie MJ (2000) Early identification of refractory epilepsy. N Engl J Med 342:314–319PubMedCrossRef
18.
Zurück zum Zitat Leiphart JW, Young RM, Shields DC (2014) A historical perspective: stereotactic lesions for the treatment of epilepsy. Seizure 23:1–5PubMedCrossRef Leiphart JW, Young RM, Shields DC (2014) A historical perspective: stereotactic lesions for the treatment of epilepsy. Seizure 23:1–5PubMedCrossRef
19.
Zurück zum Zitat Liščák R, Malíková H, Kalina M, Vojtěch Z, Procházka T, Marusič P, Vladyka V (2010) Stereotactic radiofrequency amygdalohippocampectomy in the treatment of mesial temporal lobe epilepsy. Acta Neurochir (Wien) 152:1291–1298CrossRef Liščák R, Malíková H, Kalina M, Vojtěch Z, Procházka T, Marusič P, Vladyka V (2010) Stereotactic radiofrequency amygdalohippocampectomy in the treatment of mesial temporal lobe epilepsy. Acta Neurochir (Wien) 152:1291–1298CrossRef
20.
Zurück zum Zitat Malíková H, Vojtěch Z, Liščák R, Procházka T, Vymazal J, Marečková I, Kalina M, Dbalý V, Keller J, Vladyka V (2010) Microsurgical and stereotactic radiofrequency amygdalohippocampectomy for the treatment of mesial temporal lobe epilepsy: different volume reduction, similar clinical seizure control. Stereotact Funct Neurosurg 88:42–50PubMedCrossRef Malíková H, Vojtěch Z, Liščák R, Procházka T, Vymazal J, Marečková I, Kalina M, Dbalý V, Keller J, Vladyka V (2010) Microsurgical and stereotactic radiofrequency amygdalohippocampectomy for the treatment of mesial temporal lobe epilepsy: different volume reduction, similar clinical seizure control. Stereotact Funct Neurosurg 88:42–50PubMedCrossRef
21.
Zurück zum Zitat Maliková H, Vojtěch Z, Liščák R, Procházka T, Vymazal J, Vladyka V, Keller J, Kalina M (2009) Stereotactic radiofrequency amygdalohippocampectomy for the treatment of mesial temporal lobe epilepsy: correlation of MRI with clinical seizure outcome. Epilepsy Res 83:235–42PubMedCrossRef Maliková H, Vojtěch Z, Liščák R, Procházka T, Vymazal J, Vladyka V, Keller J, Kalina M (2009) Stereotactic radiofrequency amygdalohippocampectomy for the treatment of mesial temporal lobe epilepsy: correlation of MRI with clinical seizure outcome. Epilepsy Res 83:235–42PubMedCrossRef
22.
Zurück zum Zitat Mathern GW, Pretorius JK, Babb TL (1995) Influence of the type of initial precipitating injury and at what age it occurs on course and outcome in patients with temporal lobe seizures. J Neurosurg 82:220–7PubMedCrossRef Mathern GW, Pretorius JK, Babb TL (1995) Influence of the type of initial precipitating injury and at what age it occurs on course and outcome in patients with temporal lobe seizures. J Neurosurg 82:220–7PubMedCrossRef
23.
Zurück zum Zitat McIntosh AM, Kalnins RM, Mitchell LA, Fabinyi GCA, Briellmann RS, Berkovic SF (2004) Temporal lobectomy: long-term seizure outcome, late recurrence and risks for seizure recurrence. Brain 127:2018–2030PubMedCrossRef McIntosh AM, Kalnins RM, Mitchell LA, Fabinyi GCA, Briellmann RS, Berkovic SF (2004) Temporal lobectomy: long-term seizure outcome, late recurrence and risks for seizure recurrence. Brain 127:2018–2030PubMedCrossRef
24.
Zurück zum Zitat Milner B (1972) Disorders of learning and memory after temporal lobe lesions in man. Clin Neurosurg 19:421–446PubMed Milner B (1972) Disorders of learning and memory after temporal lobe lesions in man. Clin Neurosurg 19:421–446PubMed
25.
Zurück zum Zitat Parrent AG, Blume WT (1999) Stereotactic amygdalohippocampectomy for the treatment of medial temporal lobe epilepsy. Epilepsia 40:1408–1416PubMedCrossRef Parrent AG, Blume WT (1999) Stereotactic amygdalohippocampectomy for the treatment of medial temporal lobe epilepsy. Epilepsia 40:1408–1416PubMedCrossRef
26.
Zurück zum Zitat Patil AA, Andrews R (2013) Long term follow-up after multiple hippocampal transection (MHT). Seizure 22:731–734PubMedCrossRef Patil AA, Andrews R (2013) Long term follow-up after multiple hippocampal transection (MHT). Seizure 22:731–734PubMedCrossRef
27.
Zurück zum Zitat Polkey CE (2003) Alternative surgical procedures to help drug-resistant epilepsy – a review. Epileptic Disord 5:63–75PubMed Polkey CE (2003) Alternative surgical procedures to help drug-resistant epilepsy – a review. Epileptic Disord 5:63–75PubMed
28.
Zurück zum Zitat Polkey CE (1996) Complications of epilepsy surgery. In: Shorvon S, Dreifuss F, Fish D, Thomas D (eds) The treatment of epilepsy. Blackwell Science Ltd, Oxford, pp 780–793 Polkey CE (1996) Complications of epilepsy surgery. In: Shorvon S, Dreifuss F, Fish D, Thomas D (eds) The treatment of epilepsy. Blackwell Science Ltd, Oxford, pp 780–793
29.
Zurück zum Zitat Régis J, Rey M, Bartolomei F, Vladyka V, Liscak R, Schröttner O, Pendl G (2004) Gamma knife surgery in mesial temporal lobe epilepsy: a prospective multicenter study. Epilepsia 45:504–515PubMedCrossRef Régis J, Rey M, Bartolomei F, Vladyka V, Liscak R, Schröttner O, Pendl G (2004) Gamma knife surgery in mesial temporal lobe epilepsy: a prospective multicenter study. Epilepsia 45:504–515PubMedCrossRef
30.
Zurück zum Zitat Schaller C, Jung A, Clusmann H, Schramm J, Meyer B (2004) Rate of vasospasm following the transsylvian versus transcortical approach for selective amygdalohippocampectomy. Neurol Res 26:666–670PubMedCrossRef Schaller C, Jung A, Clusmann H, Schramm J, Meyer B (2004) Rate of vasospasm following the transsylvian versus transcortical approach for selective amygdalohippocampectomy. Neurol Res 26:666–670PubMedCrossRef
31.
Zurück zum Zitat Schramm J (2008) Temporal lobe epilepsy surgery and the quest for optimal extent of resection: a review. Epilepsia 49:1296–1307PubMed Schramm J (2008) Temporal lobe epilepsy surgery and the quest for optimal extent of resection: a review. Epilepsia 49:1296–1307PubMed
32.
Zurück zum Zitat Soeder BM, Gleissner U, Urbach H, Clusmann H, Elger CE, Vincent A, Bien CG (2009) Causes, presentation and outcome of lesional adult onset mediotemporal lobe epilepsy. J Neurol Neurosurg Psychiatry 80:894–899PubMedCrossRef Soeder BM, Gleissner U, Urbach H, Clusmann H, Elger CE, Vincent A, Bien CG (2009) Causes, presentation and outcome of lesional adult onset mediotemporal lobe epilepsy. J Neurol Neurosurg Psychiatry 80:894–899PubMedCrossRef
33.
Zurück zum Zitat Spooner CG, Berkovic SF, Mitchell LA, Wrennall JA, Harvey AS (2006) New-onset temporal lobe epilepsy in children: lesion on MRI predicts poor seizure outcome. Neurology 67:2147–2153PubMedCrossRef Spooner CG, Berkovic SF, Mitchell LA, Wrennall JA, Harvey AS (2006) New-onset temporal lobe epilepsy in children: lesion on MRI predicts poor seizure outcome. Neurology 67:2147–2153PubMedCrossRef
34.
Zurück zum Zitat Srikijvilaikul T, Najm I, Foldvary-Schaefer N, Lineweaver T, Suh JH, Bingaman WE (2004) Failure of gamma knife radiosurgery for mesial temporal lobe epilepsy: report of five cases. Neurosurgery 54:1395–1402PubMedCrossRef Srikijvilaikul T, Najm I, Foldvary-Schaefer N, Lineweaver T, Suh JH, Bingaman WE (2004) Failure of gamma knife radiosurgery for mesial temporal lobe epilepsy: report of five cases. Neurosurgery 54:1395–1402PubMedCrossRef
35.
Zurück zum Zitat Vojtěch Z, Krámská L, Malíková H, Seltenreichová K, Procházka T, Kalina M, Liščák R (2012) Cognitive outcome after stereotactic amygdalohippocampectomy. Seizure 21:327–333PubMedCrossRef Vojtěch Z, Krámská L, Malíková H, Seltenreichová K, Procházka T, Kalina M, Liščák R (2012) Cognitive outcome after stereotactic amygdalohippocampectomy. Seizure 21:327–333PubMedCrossRef
36.
Zurück zum Zitat Vojtěch Z, Vladyka V, Kalina M, Nešpor E, Seltenreichová K, Šemnická J, Liščák R (2009) The use of radiosurgery for the treatment of mesial temporal lobe epilepsy and long-term results. Epilepsia 50:2061–2071PubMedCrossRef Vojtěch Z, Vladyka V, Kalina M, Nešpor E, Seltenreichová K, Šemnická J, Liščák R (2009) The use of radiosurgery for the treatment of mesial temporal lobe epilepsy and long-term results. Epilepsia 50:2061–2071PubMedCrossRef
37.
Zurück zum Zitat Wiebe S, Blume WT, Girvin JP, Eliasziw M (2001) A randomized, controlled trial of surgery for temporal-lobe epilepsy. N Engl J Med 345:311–318PubMedCrossRef Wiebe S, Blume WT, Girvin JP, Eliasziw M (2001) A randomized, controlled trial of surgery for temporal-lobe epilepsy. N Engl J Med 345:311–318PubMedCrossRef
38.
Zurück zum Zitat Wyler AR, Hermann BP, Somes G, Spencer DD, Roberts DW, Engel J Jr (1995) Extent of medial temporal resection on outcome from anterior temporal lobectomy: a randomized prospective study. Neurosurgery 37:982–991PubMedCrossRef Wyler AR, Hermann BP, Somes G, Spencer DD, Roberts DW, Engel J Jr (1995) Extent of medial temporal resection on outcome from anterior temporal lobectomy: a randomized prospective study. Neurosurgery 37:982–991PubMedCrossRef
Metadaten
Titel
Long-term seizure outcome after stereotactic amygdalohippocampectomy
verfasst von
Zdeněk Vojtěch
Hana Malíková
Lenka Krámská
Jiří Anýž
Martin Syrůček
Josef Zámečník
Roman Liščák
Vilibald Vladyka
Publikationsdatum
01.08.2014
Verlag
Springer Vienna
Erschienen in
Acta Neurochirurgica / Ausgabe 8/2014
Print ISSN: 0001-6268
Elektronische ISSN: 0942-0940
DOI
https://doi.org/10.1007/s00701-014-2126-5

Weitere Artikel der Ausgabe 8/2014

Acta Neurochirurgica 8/2014 Zur Ausgabe

Leitlinien kompakt für die Neurologie

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Hirnblutung unter DOAK und VKA ähnlich bedrohlich

17.05.2024 Direkte orale Antikoagulanzien Nachrichten

Kommt es zu einer nichttraumatischen Hirnblutung, spielt es keine große Rolle, ob die Betroffenen zuvor direkt wirksame orale Antikoagulanzien oder Marcumar bekommen haben: Die Prognose ist ähnlich schlecht.

Was nützt die Kraniektomie bei schwerer tiefer Hirnblutung?

17.05.2024 Hirnblutung Nachrichten

Eine Studie zum Nutzen der druckentlastenden Kraniektomie nach schwerer tiefer supratentorieller Hirnblutung deutet einen Nutzen der Operation an. Für überlebende Patienten ist das dennoch nur eine bedingt gute Nachricht.

Thrombektomie auch bei großen Infarkten von Vorteil

16.05.2024 Ischämischer Schlaganfall Nachrichten

Auch ein sehr ausgedehnter ischämischer Schlaganfall scheint an sich kein Grund zu sein, von einer mechanischen Thrombektomie abzusehen. Dafür spricht die LASTE-Studie, an der Patienten und Patientinnen mit einem ASPECTS von maximal 5 beteiligt waren.

Update Neurologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.