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Heart Failure Reviews
Erschienen in: Heart Failure Reviews 2/2014

01.03.2014

Co-morbidities in heart failure

verfasst von: Vincent M. van Deursen, Kevin Damman, Peter van der Meer, Peter J. Wijkstra, Gert-Jan Luijckx, Andre van Beek, Dirk J. van Veldhuisen, Adriaan A. Voors

Erschienen in: Heart Failure Reviews | Ausgabe 2/2014

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Abstract

Heart failure is a clinical syndrome characterized by poor quality of life and high morbidity and mortality. Co-morbidities frequently accompany heart failure and further decrease in both quality of life and clinical outcome. We describe that the prevalence of co-morbidities in patients with heart failure is much higher compared to age-matched controls. We will specifically address the most studied organ-related co-morbidities, that is, renal dysfunction, cerebral dysfunction, anaemia, liver dysfunction, chronic obstructive pulmonary disease, diabetes mellitus and sleep apnoea. The pathophysiologic processes underlying the interaction between heart failure and co-morbid conditions are complex and remain largely unresolved. Although common risk factors are likely to contribute, it is reasonable to believe that factors associated with heart failure might cause other co-morbid conditions. Inflammation, neurohumoral pathway activation and hemodynamic changes are potential factors. We try to provide explanations for the observed association between co-morbidities and heart failure, as well as its impact on survival.
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Metadaten
Titel
Co-morbidities in heart failure
verfasst von
Vincent M. van Deursen
Kevin Damman
Peter van der Meer
Peter J. Wijkstra
Gert-Jan Luijckx
Andre van Beek
Dirk J. van Veldhuisen
Adriaan A. Voors
Publikationsdatum
01.03.2014
Verlag
Springer US
Erschienen in
Heart Failure Reviews / Ausgabe 2/2014
Print ISSN: 1382-4147
Elektronische ISSN: 1573-7322
DOI
https://doi.org/10.1007/s10741-012-9370-7

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