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Erschienen in: Journal of Assisted Reproduction and Genetics 11/2012

01.11.2012 | ASSISTED REPRODUCTION TECHNOLOGIES

Assessment and treatment of repeated implantation failure (RIF)

verfasst von: Alex Simon, Neri Laufer

Erschienen in: Journal of Assisted Reproduction and Genetics | Ausgabe 11/2012

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Abstract

Repeated implantation failure (RIF) is determined when embryos of good quality fail to implant following several in vitro fertilization (IVF) treatment cycles. Implantation failure is related to either maternal factors or embryonic causes. Maternal factors include uterine anatomic abnormalities, thrombophilia, non-receptive endometrium and immunological factors. Failure of implantation due to embryonic causes is associated with either genetic abnormalities or other factors intrinsic to the embryo that impair its ability to develop in utero, to hatch and to implant. New methods of time-lapse imaging of embryos and assessment of their metabolic functions may improve selection of embryos for transfer, and subsequent outcomes for IVF patients, as well as for those diagnosed with RIF. This review discusses the various causes associated with RIF and addresses appropriate treatments.
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Metadaten
Titel
Assessment and treatment of repeated implantation failure (RIF)
verfasst von
Alex Simon
Neri Laufer
Publikationsdatum
01.11.2012
Verlag
Springer US
Erschienen in
Journal of Assisted Reproduction and Genetics / Ausgabe 11/2012
Print ISSN: 1058-0468
Elektronische ISSN: 1573-7330
DOI
https://doi.org/10.1007/s10815-012-9861-4

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