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Erschienen in:
01.07.2015 | Original Article
Lung cancer surgery in patients aged 80 years or older: an analysis of risk factors, morbidity, and mortality
Erschienen in: General Thoracic and Cardiovascular Surgery | Ausgabe 7/2015
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Introduction
As the population ages, the age of patients undergoing thoracic surgery increases, and elderly patients often have more comorbidities than younger patients.
Methods
This retrospective study observed preoperative comorbidities, surgical procedures and postoperative morbidity and mortality after lung cancer surgery in patients 80 years of age or older. The medical records of lung cancer patients 80 years of age or older who underwent surgery from January 2003 to December 2012 were reviewed.
Results
There were 49 patients (27 males, 22 females), with a median age of 83 years. Thirty patients underwent major pulmonary resection and 18 patients underwent limited pulmonary resection. The median Charlson comorbidity index was 3. Although approximately two-thirds of the patients (20 patients; 40.8 %) experienced some kind of postoperative morbidity, more than 80 % of the complications were grade 1 or 2 according to the Clavien–Dindo classification. Cerebrovascular disease and chronic obstructive pulmonary disease were significantly associated with moderate-to-severe complications. Postoperative death was observed in two cases (4.1 %). In addition, an increased American Society of Anesthesiologists classification score and past history of myocardial infarction, congestive heart failure and/or diabetes mellitus with end-organ damage were significantly associated with mortality. The overall survival rate was 79.6 % at 3 years and 53.1 % at 5 years.
Conclusions
Thoracic surgery shows acceptable morbidity and mortality in patients 80 years of age or older. Patients 80 years of age or older should be offered the best treatments, including surgery, with careful patient evaluation and selection.