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12.02.2022 | Mini Review

Adrenal schwannoma: why should endocrinologists be aware of this uncommon tumour?

verfasst von: Giuseppina Incampo, Luigi Di Filippo, Erika Maria Grossrubatscher, Paolo Dalino Ciaramella, Stefano Frara, Andrea Giustina, Paola Loli

Erschienen in: Endocrine | Ausgabe 3/2022

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Abstract

Purpose

Adrenal schwannomas (AS) are rare tumours arising from Schwann cells. Due to the high prevalence of adrenal incidentalomas, running into very rare adrenal tumours has become a possibility for high volume expert centres. So far, the clinical behaviour and the radiological characteristics of AS make the pre-operative diagnosis of AS extremely challenging. Due to limited information available, we wanted to summarise the main features of this tumours, in order to raise the profile of an uncommon disease.

Methods

We performed a MEDLINE and EMBASE research to review the literature. We found 57 case reports and case series and a total of 169 cases, including 2 more cases found in our Institutions. We collected data regarding year of publication, sex, age, and, when available, clinical presentation, hormonal data, radiological features, tumour site and size, treatment, histology and follow-up.

Results

We analysed and discussed the clinical, radiological and pathological characteristics of cases identified, underlying the critical aspects of assessment and management of these tumours which still remain questioned, as, currently, pathologic examination is the only way to make the diagnosis.

Conclusions

The pre-operative diagnosis of AS is more than challenging and pathologic examination is so far the only way to make a certain diagnosis. Therefore, it is important to consider also the AS in the list of possible diagnoses when faced with a large not secreting adrenal tumour, with suspicious radiological features.

S. Bovio, A. Cataldi, G. Reimondo, P. Sperone, S. Novello, A. Berruti, P. Borasio, C. Fava, L. Dogliotti, G.V. Scagliotti, A. Angeli, M. Terzolo, Prevalence of adrenal incidentaloma in a contemporary computerized tomography series. J. Endocrinol. Investig. 29(4), 298–302 (2006). https://doi.org/10.1007/BF03344099CrossRef

B.K. Goh, Y.M. Tan, Y.F. Chung, P.K. Chow, L.L. Ooi, W.K. Wong, Retroperitoneal schwannoma. Am. J. Surg. 192(1), 14–18 (2006). https://doi.org/10.1016/j.amjsurg.2005.12.010CrossRefPubMed

Lam, A., Just, P., Lack, E., Tissier, F., Weiss, L.: Schwannoma. In: Lloyd, R.V.; Osamura, R.Y.; Kloppel, G.; Rosai, J. (eds) WHO Classification of Tumours: Pathology and Genetics of Tumours of Endocrine Organs. 4th ed. International Agency for Research on Cancer (IARC), Lyon 10, 176 (2017).

Perry, A., Jo, V.: Peripheral nerve sheath tumours—schwannoma. In: W.H.O. Classification of Tumours Editorial Board, Soft Tissue and Bone Tumours. WHO Classification of Tumours. 5th edition. International Agency for Research on Cancer (IARC), Lyon 3, 226–231 (2020).

M. Salvati, P. Ciappetta, A. Raco, R. Capone, M. Artico, A. Santoro, Radiation-induced schwannomas of the neuraxis. Report of threee cases. Tumor. 78(2), 143–146 (1992)CrossRef

J.A. Trofatter, M.M. MacCollin, J.L. Rutter, J.R. Murrell, M.P. Duyao, D.M. Parry, R. Eldridge, N. Kley, A.G. Menon, K. Pulaski et al. A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor. Cell 75(4), 826 (1993). https://doi.org/10.1016/0092-8674(93)90501-gCrossRefPubMed

T.J. Hulsebos, A.S. Plomp, R.A. Wolterman, E.C. Robanus-Maandag, F. Baas, P. Wesseling, Germline mutation of INI1/SMARCB1 in familial schwannomatosis. Am. J. Hum. Genet. 80(4), 805–810 (2007). https://doi.org/10.1086/513207CrossRefPubMedPubMedCentral

A. Piotrowski, J. Xie, Y.F. Liu, A.B. Poplawski, A.R. Gomes, P. Madanecki, C. Fu, M.R. Crowley, D.K. Crossman, L. Armstrong, D. Babovic-Vuksanovic, A. Bergner, J.O. Blakeley, A.L. Blumenthal, M.S. Daniels, H. Feit, K. Gardner, S. Hurst, C. Kobelka, C. Lee, R. Nagy, K.A. Rauen, J.M. Slopis, P. Suwannarat, J.A. Westman, A. Zanko, B.R. Korf, L.M. Messiaen, Germline loss-of-function mutations in LZTR1 predispose to an inherited disorder of multiple schwannomas. Nat. Genet. 46(2), 182–187 (2014). https://doi.org/10.1038/ng.2855CrossRefPubMed

N. Onoda, T. Ishikawa, T. Toyokawa, T. Takashima, K. Wakasa, K. Hirakawa, Adrenal schwannoma treated with laparoscopic surgery. JSLS 12(4), 420–425 (2008)PubMedPubMedCentral

10.

J. Zhou, D. Zhang, W. Li, L. Zhou, H. Xu, S. Zheng, C. Wang, Primary adrenal schwannoma: a series of 31 cases emphasizing their clinicopathologic features and favorable prognosis. Endocrine 65(3), 662–674 (2019). https://doi.org/10.1007/s12020-019-01992-zCrossRefPubMed

11.

J.M. Maciel, D.V. Pereira, H.F. Simoes, V.A. Leite, Adrenal microcystic reticular schwannoma. AACE Clin. Case Rep. 5(4), e250–e254 (2019). https://doi.org/10.4158/ACCR-2018-0621CrossRefPubMedPubMedCentral

12.

J. Zhou, D. Zhang, G. Wang, W. Li, J. Xu, Y. Ma, J. Zhang, Z. Li, Z. Zhao, Primary adrenal microcystic/reticular schwannoma: clinicopathological and immunohistochemical studies of an extremely rare case. Int. J. Clin. Exp. Pathol. 8(5), 5808–5811 (2015)PubMedPubMedCentral

13.

Y.Y. Hou, Y.S. Tan, J.F. Xu, X.N. Wang, S.H. Lu, Y. Ji, J. Wang, X.Z. Zhu, Schwannoma of the gastrointestinal tract: a clinicopathological, immunohistochemical and ultrastructural study of 33 cases. Histopathology 48(5), 536–545 (2006). https://doi.org/10.1111/j.1365-2559.2006.02370.xCrossRefPubMed

14.

M. de Vries, P.C. Hogendoorn, I. Briaire-de Bruyn, M.J. Malessy, A.G: van der Mey, Intratumoral hemorrhage, vessel density, and the inflammatory reaction contribute to volume increase of sporadic vestibular schwannomas. Virchows Arch.: Int. J. Pathol. 460(6), 629–636 (2012). https://doi.org/10.1007/s00428-012-1236-9CrossRef

15.

M. de Vries, I. Briaire-de Bruijn, M.J. Malessy, S.F. de Bruine, A.G. van der Mey, P.C. Hogendoorn, Tumor-associated macrophages are related to volumetric growth of vestibular schwannomas. Otol. Neurotol. 34(2), 347–352 (2013). https://doi.org/10.1097/MAO.0b013e31827c9fbfCrossRefPubMed

16.

S.W. Weiss, J.M. Langloss, F.M. Enzinger, Value of S-100 protein in the diagnosis of soft tissue tumors with particular reference to benign and malignant Schwann cell tumors. Lab. Invest. 49(3), 299–308 (1983)PubMed

17.

D. Nonaka, L. Chiriboga, B.P. Rubin, Sox10: a pan-schwannian and melanocytic marker. Am. J. Surg. Pathol. 32(9), 1291–1298 (2008). https://doi.org/10.1097/PAS.0b013e3181658c14CrossRefPubMed

18.

L. Zheng, X. Wu, M.E. Kreis, Z. Yu, L. Feng, C. Chen, B. Xu, Z. Bu, Z. Li, J. Ji, Clinicopathological and immunohistochemical characterisation of gastric schwannomas in 29 cases. Gastroenterol. Res. Pract. 2014, 202960 (2014). https://doi.org/10.1155/2014/202960CrossRefPubMedPubMedCentral

19.

S.A. Vinores, J.M. Bonnin, L.J. Rubinstein, P.J. Marangos, Immunohistochemical demonstration of neuron-specific enolase in neoplasms of the CNS and other tissues. Arch. Pathol. Lab. Med. 108(7), 536–540 (1984)PubMed

20.

J. Xie, C. Wang, H. Wang, Microcystic/reticular schwannoma of the adrenal gland: a case report and literature review. Hum. Pathol. Case Rep. 13, 11–15 (2018). https://doi.org/10.1016/j.ehpc.2018.03.001CrossRef

21.

H.L. Hsiao, C.C. Li, H.C. Lin, H.C. Yeh, C.H. Huang, W.J. Wu, Adrenal schwannoma treated with laparoscopic adrenalectomy: a case report. Kaohsiung J. Med. Sci. 24(10), 553–557 (2008). https://doi.org/10.1016/S1607-551X(09)70016-6CrossRefPubMed

22.

J.D. Jakowski, P.E. Wakely Jr., R.E. Jimenez, An uncommon type of adrenal incidentaloma: a case report of a schwannoma of the adrenal medulla with cytological, histological, and ultrastructural correlation. Ann. Diagn. Pathol. 12(5), 356–361 (2008). https://doi.org/10.1016/j.anndiagpath.2008.06.003CrossRefPubMed

23.

Y.C. Bedard, E. Horvath, K. Kovacs, Adrenal schwannoma with apparent uptake of immunoglobulins. Ultrastruct. Pathol. 10(6), 505–513 (1986). https://doi.org/10.3109/01913128609007208CrossRefPubMed

24.

G. Tezel, N. Karaman, D. Karakoc, K. Yorganci, Giant juxtadrenal and adrenal schwannoma with concurrent adrenal myelolipoma mimicking an adrenal malignant tumor. Turk. J. Med. Sci. 35, 255–258 (2005)

25.

K. Yang, H. Lee, W. Wu, Y. Juan, M. Jang, H. Wang, J. Shen, Ancient schwannoma and myelolipoma coexist in an adrenal incidentaloma. Urol. Sci. 26(2), 134–138 (2015). https://doi.org/10.1016/j.urols.2015.01.007CrossRef

26.

M. Gomez, R. Mehta, A rare case of adrenal collision tumor: myelolipoma and schwannoma in the adrenal gland. SAGE Open Med. Case Rep. 8, 2050313X20921074 (2020). https://doi.org/10.1177/2050313X20921074CrossRefPubMedPubMedCentral

27.

C.S. Wilson, R.G. Middleton, Suprarenal neurilemoma. Urology 5(5), 707–709 (1975). https://doi.org/10.1016/0090-4295(75)90138-7CrossRefPubMed

28.

Z. Bayramoglu, E. Karli, Primary adrenal schwannoma. Pediatr. Radio. 51(Suppl 1), S1–S259 (2021)

29.

N. Babaya, Y. Makutani, S. Noso, Y. Hiromine, H. Ito, Y. Taketomo, K. Ueda, H. Ushijima, Y. Komoike, Y. Yamazaki, H. Sasano, Y. Kawabata, H. Ikegami, Case report: schwannoma arising from the unilateral adrenal area with bilateral hyperaldosteronism. BMC Endocr. Disord. 17(1), 74 (2017). https://doi.org/10.1186/s12902-017-0225-zCrossRefPubMedPubMedCentral

30.

K. Suzuki, A. Nakanishi, Y. Kurosaki, J. Nogaki, E. Takaba, Adrenal schwannoma: CT and MRI findings. Radiat. Med. 25(6), 299–302 (2007). https://doi.org/10.1007/s11604-007-0136-4CrossRefPubMed

31.

H. Salhi, M.Y.A. Lamrani, N. Hammas, O. Abdelmalek, H. El Ouahabi, A laparoscopic treatment of a suspicious adrenal mass revealing an unsual cause of adrenal incidentaloma. Pan Afr. Med. J. 34, 28 (2019). https://doi.org/10.11604/pamj.2019.34.28.18239CrossRefPubMedPubMedCentral

32.

C. Xiao, B. Xu, H. Ye, Q. Yang, L. Wang, Y.H. Sun, Experience with adrenal schwannoma in a Chinese population of six patients. J. Endocrinol. Investig. 34(6), 417–421 (2011). https://doi.org/10.1007/BF03346705CrossRef

33.

W. Zhou, Y. Zhu, L. Zhang, S. Xu, W. Zhan, Sonographic appearances of adrenal schwannomas. J. Clin. Ultrasound 47(1), 3–8 (2019). https://doi.org/10.1002/jcu.22644CrossRefPubMed

34.

M. Fassnacht, O.M. Dekkers, T. Else, E. Baudin, A. Berruti, R. de Krijger, H.R. Haak, R. Mihai, G. Assie, M. Terzolo, European Society of Endocrinology Clinical Practice Guidelines on the management of adrenocortical carcinoma in adults, in collaboration with the European Network for the Study of Adrenal Tumors. Eur. J. Endocrinol./Eur. Federation Endocr. Soc. 179(4), G1–G46 (2018). https://doi.org/10.1530/EJE-18-0608CrossRef

35.

K.K. Richter, R. Premkumar, H.S. Yoon, P. Mercer, Laparoscopic adrenalectomy for a rare 14-cm adrenal schwannoma. Surg. Laparosc. Endosc. Percutan Technol. 21(6), e339–e343 (2011). https://doi.org/10.1097/SLE.0b013e31823ac4d4CrossRef

36.

W. Tang, X.R. Yu, L.P. Zhou, H.B. Gao, Q.F. Wang, W.J. Peng, Adrenal schwannoma: CT, MR manifestations and pathological correlation. Clin. Hemorheol. Microcirc. 68(4), 401–412 (2018). https://doi.org/10.3233/CH-170316CrossRefPubMed

37.

J.J. Park, B.K. Park, C.K. Kim, Adrenal imaging for adenoma characterization: imaging features, diagnostic accuracies and differential diagnoses. Br. J. Radio. 89(1062), 20151018 (2016). https://doi.org/10.1259/bjr.20151018CrossRef

38.

Y.M. Zhang, P.F. Lei, M.N. Chen, X.F. Lv, Y.H. Ling, P.Q. Cai, J.M. Gao, CT findings of adrenal schwannoma. Clin. Radio. 71(5), 464–470 (2016). https://doi.org/10.1016/j.crad.2016.01.010CrossRef

39.

P.H. Shivalingaiah, P. Kumar, S. Bajoria, Adrenal schwannoma treated with open adrenalectomy: a case report. Indian J. Surg. Oncol. 9(1), 83–85 (2018). https://doi.org/10.1007/s13193-017-0715-5CrossRefPubMed

40.

J. Hou, L. Zhang, Y. Guo, H. Chen, W. Wang, Primary adrenal schwannoma with catecholamine hypersecretion. Arch. Med. Sci. 12(3), 681–683 (2016). https://doi.org/10.5114/aoms.2016.59942CrossRefPubMedPubMedCentral

41.

M.P. Wilson, P. Katlariwala, J. Huang, G. Low, E. Wiebe, Benign adrenal and suprarenal retroperitoneal schwannomas can mimic aggressive adrenal malignancies: case report and review of the literature. Intractable Rare Dis. Res. 9(3), 156–162 (2020). https://doi.org/10.5582/irdr.2020.01027CrossRefPubMedPubMedCentral

42.

S.E. Rha, J.Y. Byun, S.E. Jung, H.J. Chun, H.G. Lee, J.M. Lee, Neurogenic tumors in the abdomen: tumor types and imaging characteristics. Radiographics 23(1), 29–43 (2003). https://doi.org/10.1148/rg.231025050CrossRefPubMed

43.

Y. Mohiuddin, M.G. Gilliland, Adrenal schwannoma: a rare type of adrenal incidentaloma. Arch. Pathol. Lab. Med. 137(7), 1009–1014 (2013). https://doi.org/10.5858/arpa.2012-0291-RSCrossRefPubMed

44.

S.Q. Li, Y.S. Zhang, J. Shi, H.Z. Li, Clinical features and retroperitoneal laparoscopic resection of adrenal schwannoma in 19 patients. Endocr. Pract.: Off. J. Am. Coll. Endocrinol. Am. Assoc. Clin. Endocrinol. 21(4), 323–329 (2015). https://doi.org/10.4158/EP14453.ORCrossRef

45.

G. Mansmann, J. Lau, E. Balk, M. Rothberg, Y. Miyachi, S.R. Bornstein, The clinically inapparent adrenal mass: update in diagnosis and management. Endocr. Rev. 25(2), 309–340 (2004). https://doi.org/10.1210/er.2002-0031CrossRefPubMed

46.

C.A. Maciel, Y.Z. Tang, G. Coniglio, A. Sahdev, Imaging of rare medullary adrenal tumours in adults. Clin. Radio. 71(5), 484–494 (2016). https://doi.org/10.1016/j.crad.2016.01.025CrossRef

47.

S. Ahlawat, L.M. Fayad, Imaging cellularity in benign and malignant peripheral nerve sheath tumors: utility of the ‘target sign’ by diffusion weighted imaging. Eur. J. Radio. 102, 195–201 (2018). https://doi.org/10.1016/j.ejrad.2018.03.018CrossRef

48.

C.G. Venkataramana, S. Sreeram, P.V. Santosh Rai, G.G. Laxman Prabhu, K.N. Sanman, S.P. Shetty, Schwannoma: an uncommon dweller in the adrenal gland. Indian J. Pathol. Microbiol. 63(3), 456–459 (2020). https://doi.org/10.4103/IJPM.IJPM_267_19CrossRefPubMed

49.

E. Tarcoveanu, G. Dimofte, C. Bradea, R. Moldovanu, A. Vasilescu, R. Anton, D. Ferariu, Adrenal schwannoma. JSLS 13(1), 116–119 (2009)PubMedPubMedCentral

50.

A. González González, R. Perea, S. Palacios Llopis, J. de Diego, Schwannoma suprarrenal benigno [A benign adrenal schwannoma]. Med. Clin. 115(13), 518–519 (2000)CrossRef

51.

M.H. AlMalki, M. Alotaibi, M.M. Ahmad, M.A.U. Rahman, T. Alharthi, Schwannoma misdiagnosed as adrenal adenoma: a case report and review of the literature. Case Rep. Endocrinol. 2020, 8020761 (2020). https://doi.org/10.1155/2020/8020761CrossRefPubMedPubMedCentral

52.

Q.Y. Liu, M. Gao, H.G. Li, X.F. Lin, S.Q. Huang, B.L. Liang, Juxta-adrenal schwannoma: dynamic multi-slice CT and MRI findings. Eur. J. Radio. 81(4), 794–799 (2012). https://doi.org/10.1016/j.ejrad.2011.01.082CrossRef

53.

M.A. Blake, M.K. Kalra, M.M. Maher, D.V. Sahani, A.T. Sweeney, P.R. Mueller, P.F. Hahn, G.W. Boland, Pheochromocytoma: an imaging chameleon. Radiographics 24(Suppl 1), S87–S99 (2004). https://doi.org/10.1148/rg.24si045506CrossRefPubMed

54.

De Vos, N., Vanhoenacker, F., Verstraete, K., Parizel, P.: Nerve sheath tumors. In: Vanhoenacker, F.M.; Parizel, P.M.; Gielen, J.L. (eds). Imaging of Soft Tissue Tumors. Springer International Publishing AG, Switzerland, 393-424 (2017).

55.

N. Bharwani, A.G. Rockall, A. Sahdev, M. Gueorguiev, W. Drake, A.B. Grossman, R.H. Reznek, Adrenocortical carcinoma: the range of appearances on CT and MRI. Am. J. Roentgenol. 196(6), W706–W714 (2011). https://doi.org/10.2214/AJR.10.5540CrossRef

56.

M.A. Blake, P. Prakash, C.G. Cronin, PET/CT for adrenal assessment. Am. J. Roentgenol. 195(2), W91–W95 (2010). https://doi.org/10.2214/AJR.09.3845CrossRef

57.

U. Metser, E. Miller, H. Lerman, G. Lievshitz, S. Avital, E. Even-Sapir, 18F-FDG PET/CT in the evaluation of adrenal masses. J. Nucl. Med. 47(1), 32–37 (2006)PubMed

58.

A.B. Elaini, S.K. Shetty, V.M. Chapman, D.V. Sahani, G.W. Boland, A.T. Sweeney, M.M. Maher, J.T. Slattery, P.R. Mueller, M.A. Blake, Improved detection and characterization of adrenal disease with PET-CT. Radiographics 27(3), 755–767 (2007). https://doi.org/10.1148/rg.273055031CrossRefPubMed

59.

C. Guerin, F. Pattou, L. Brunaud, J.C. Lifante, E. Mirallie, M. Haissaguerre, D. Huglo, P. Olivier, C. Houzard, C. Ansquer, E. Hindie, A. Loundou, C. Archange, A. Tabarin, F. Sebag, K. Baumstarck, D. Taieb, Performance of 18F-FDG PET/CT in the characterization of adrenal masses in noncancer patients: a prospective study. J. Clin. Endocrinol. Metab. 102(7), 2465–2472 (2017). https://doi.org/10.1210/jc.2017-00254CrossRefPubMed

60.

G.W. Boland, B.A. Dwamena, M. Jagtiani Sangwaiya, A.G. Goehler, M.A. Blake, P.F. Hahn, J.A. Scott, M.K. Kalra, Characterization of adrenal masses by using FDG PET: a systematic review and meta-analysis of diagnostic test performance. Radiology 259(1), 117–126 (2011). https://doi.org/10.1148/radiol.11100569CrossRefPubMed

61.

S.J. Kim, S.W. Lee, K. Pak, I.J. Kim, K. Kim, Diagnostic accuracy of (18)F-FDG PET or PET/CT for the characterization of adrenal masses: a systematic review and meta-analysis. Br. J. Radio. 91(1086), 20170520 (2018). https://doi.org/10.1259/bjr.20170520CrossRef

62.

S. Beaulieu, B. Rubin, D. Djang, E. Conrad, E. Turcotte, J.F. Eary, Positron emission tomography of schwannomas: emphasizing its potential in preoperative planning. Am. J. Roentgenol. 182(4), 971–974 (2004). https://doi.org/10.2214/ajr.182.4.1820971CrossRef

63.

K.K. Miyake, Y. Nakamoto, T.R. Kataoka, C. Ueshima, T. Higashi, T. Terashima, K. Nakatani, T. Saga, S. Minami, K. Togashi, Clinical, morphologic, and pathologic features associated with increased FDG uptake in schwannoma. Am. J. Roentgenol. 207(6), 1288–1296 (2016). https://doi.org/10.2214/AJR.15.14964CrossRef

64.

G. Dell’Aversano Orabona, D. Ricci, I. Emili, F. Serpi, V. Ferrara, A. Vanzulli, Adrenal schwannoma: a case report. BJR Case Rep. 6(1), 20190044 (2020). https://doi.org/10.1259/bjrcr.20190044CrossRefPubMedPubMedCentral

65.

K. Yorita, T. Naroda, M. Tamura, S. Ito, K. Nakatani, Adrenal schwannoma in an elderly man: a case report and literature review. Intern. Med. 61(1), 65–69 (2022). https://doi.org/10.2169/internalmedicine.7026-21CrossRefPubMed

66.

A. Oberoi, K. Kataria, O. Prakash, R. Yadav, A. Goyal, Management of giant adrenal schwannoma. Int. Surg. J. 6(7), 2605–2608 (2019). https://doi.org/10.18203/2349-2902.isj20193003CrossRef

67.

K.G. Toutouzas, D. Tsamis, P.B. Kekis, N.V. Michalopoulos, I. Flessas, A. Manouras, G. Zografos, Z. Geogrios, Laparoscopic resection of an adrenal schwannoma. JSLS 16(4), 663–667 (2012). https://doi.org/10.4293/108680812X13517013316753CrossRefPubMed

68.

T. Igawa, H. Hakariya, M. Tomonaga, Primary adrenal schwannoma. Nihon Hinyokika Gakkai Zasshi 89(5), 567–570 (1998). https://doi.org/10.5980/jpnjurol1989.89.567CrossRefPubMed

69.

I. Ikemoto, T. Yumoto, Y. Yoshino, N. Furuta, H. Kiyota, Y. Oishi, Schwannoma with purely cystic form originating from the adrenal area: a case report. Hinyokika Kiyo 48(5), 289–291 (2002)PubMed

70.

S.K. Lau, D.V. Spagnolo, L.M. Weiss, Schwannoma of the adrenal gland: report of two cases. Am. J. Surg. Pathol. 30(5), 630–634 (2006). https://doi.org/10.1097/01.pas.0000194739.80174.26CrossRefPubMed

71.

S. Gazula, K.J. Mammen, Schwannoma with concomitant tuberculosis in the adrenal gland. Indian J. Urol. 23(4), 469–470 (2007). https://doi.org/10.4103/0970-1591.36724CrossRefPubMedPubMedCentral

72.

R. Korets, R. Berkenblit, R. Ghavamian, Incidentally discovered adrenal schwannoma. JSLS 11(1), 113–115 (2007)PubMedPubMedCentral

73.

C.Y. Yang, C.W. Chou, M.B. Lin, C.F. Li, Schwannomas of the left adrenal gland and posterior mediastinum. J. Chin. Med. Assoc. 72(2), 83–87 (2009). https://doi.org/10.1016/S1726-4901(09)70028-0CrossRefPubMed

74.

M. Adas, F. Ozulker, G. Adas, B. Koc, T. Ozulker, I.M. Sahin, A rare adrenal incidentaloma: adrenal schwannoma. Case Rep. Gastroenterol. 7(3), 420–427 (2013). https://doi.org/10.1159/000355871CrossRefPubMedPubMedCentral

75.

S. Hernandez Dominguez, J.M. Muguerza Huguet, M.M. Diez Alonso, A. Gonzalez Estecha, Adrenal intranodal schwannoma. Cir. Esp. 92(10), 695–696 (2014). https://doi.org/10.1016/j.ciresp.2012.09.007CrossRefPubMed

76.

A. Jeshtadi, N. Govada, S. Somalwar, S. Nagulapally, Schwannoma of the adrenal gland. J. Med. Allied Sci. 4(2), 77–80 (2014)

77.

R. Blanco Fernandez, L. Rodriguez Villamil, S. Fernandez-Pello Montes, B. Diaz Mendez, J.M. Pello Fonseca, C. Luz Menendez, C. Perez Garcia, R.G. Ugarteburu, I. Gonzalez Rodriguez, J. Mosquera Madera, Management of retroperitoneal schwannoma: case reports and review of the literature. World J. Nep. Urol. 5(3), 58–62(2016).CrossRef

78.

H.J. Yun, S.Y. Kim, S.M. Kim, B.-W. Kim, Y.S. Lee, H.-S. Chang, C.S. Park, Adrenal schwannoma: rare entity of adrenal incidentaloma. Korean J. Endocr. Surg. 16(4), 107–111 (2016)CrossRef

79.

S. Kumar, V.S. Karthikeyan, C.S. Manohar, K. Sreelakshmi, M. Shivalingaiah, Adrenal schwannoma: a rare incidentaloma. J. Clin. Diagn. Res. 10(8), PD01–PD02 (2016). https://doi.org/10.7860/JCDR/2016/20405.8265CrossRefPubMedPubMedCentral

80.

S. Said, R. Muhammad, H. Othman, S. Othman, N. Rashid, R. Zin, Adrenal schwannoma: a rare type of adrenal incidentaloma. World J. Endoc. Surg. 9(3), 111–114 (2017). https://doi.org/10.5005/jp-journals-10002-1223CrossRef

81.

Thomas, M., Stephen, J.: Adrenal schwannoma: a rare adrenal incidentaloma. Int. Surg. J. 5(1967–1969) (2018).

82.

W. Shabana, W. Raslan, S. Hassan, T. Al-Tartir, Schwannoma masquerading as adrenocortical tumor: a case report and review of literature. Urol. Case Rep. 26, 100926 (2019). https://doi.org/10.1016/j.eucr.2019.100926CrossRefPubMedPubMedCentral

83.

T. Ma, W.Z. Yang, Z. Cui, C. Zhao, Experience in the application of laparoscopic anatomical adrenalectomy via the renal cortex surface monolayer. Pak. J. Med. Sci. 36(4), 717–722 (2020). https://doi.org/10.12669/pjms.36.4.2102CrossRefPubMedPubMedCentral

84.

Y. Yi, C. Lin, F. Yu, J. Zhang, Q. Chen, L.U. Song, A big encapsulated adrenal mass with well-circumscribed margin. Urol. Case Rep. 35, 101536 (2021). https://doi.org/10.1016/j.eucr.2020.101536CrossRefPubMed

85.

M. Jafif Cojab, J. Flores Armenta, D.L. Jorge, R. Sanchez Hernandez, O. Cervantes Gutierrez, M. Brener Chaoul, K. Moedano Rico, R. Cuevas Bustos, F.A. Perez Tristan, A. Acuna Macouzet, M. Gonzalez Woge, L.M. Zamora Duarte, G. Cervantes Millan, J.M. Melendez Sanchez, A.K. Garcia Mendez, Adrenal schwannoma in a female patient; a rare benign neoplasm: case report and literature review. Int. J. Surg. Case Rep. 74, 173–176 (2020). https://doi.org/10.1016/j.ijscr.2020.07.063CrossRefPubMedPubMedCentral

86.

S. Timilsina, S.P. Joshi, S. Sharma, S. Kharel, S. Karki, S.B. Tiwari, D. Pandit, P. Parajuli, Adrenal schwannoma: a case report of an unusual incidentaloma. Int. J. Surg. Case Rep. 83, 106018 (2021). https://doi.org/10.1016/j.ijscr.2021.106018CrossRefPubMedPubMedCentral

87.

A. Janjua, M.Z. Sarwar, S.A. Naqi, Adrenal schwannoma: a case report. Int. Med. Case Rep. J. 14, 617–620 (2021). https://doi.org/10.2147/IMCRJ.S311777CrossRefPubMedPubMedCentral

88.

C. Fuentes, L. Garaizabal, O. Perez, Adrenal schwannoma: a case report. Med. Clin. 157(2), 90–91 (2021). https://doi.org/10.1016/j.medcli.2020.04.060CrossRef

89.

H. Huang, Q. Ding, X. Lin, D. Li, J. Zeng, W. Fu, Clinical features and outcomes of adrenal schwannoma: a study of 13 cases from a single centre. Endocr. Connect 10(5), 543–549 (2021). https://doi.org/10.1530/EC-21-0062CrossRefPubMedPubMedCentral

Titel: Adrenal schwannoma: why should endocrinologists be aware of this uncommon tumour?
verfasst von: Giuseppina Incampo
Luigi Di Filippo
Erika Maria Grossrubatscher
Paolo Dalino Ciaramella
Stefano Frara
Andrea Giustina
Paola Loli
Publikationsdatum: 12.02.2022
Verlag: Springer US
Erschienen in: Endocrine / Ausgabe 3/2022
Print ISSN: 1355-008X
Elektronische ISSN: 1559-0100
DOI: https://doi.org/10.1007/s12020-022-02997-x

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