Skip to main content
Erschienen in: Canadian Journal of Anesthesia/Journal canadien d'anesthésie 1/2009

01.01.2009 | Special Article

Posing the research question: not so simple

verfasst von: Lehana Thabane, PhD, Tara Thomas, MD, Chenglin Ye, BSc, James Paul, MD

Erschienen in: Canadian Journal of Anesthesia/Journal canadien d'anesthésie | Ausgabe 1/2009

Einloggen, um Zugang zu erhalten

Abstract

Purpose

The success of any research process relies, in part, on how well investigators are able to translate a clinical problem into a research question—a task that is not so simple for novice investigators. The PICOT approach requires that the framing of the research question specify the target Population, the Intervention of interest, the Comparator intervention, key Outcomes, and the Time frame over which the outcomes are assessed. This paper describes the use of the PICOT structure in framing research questions and examines PICOT criteria as applied to the anesthesia literature. We also provide a roadmap for applying the PICOT format in identifying and framing clear research questions.

Methods

In addition to searching MEDLINE for the literature on framing research questions, we performed a systematic review of articles published in four key anesthesia journals in 2006, including Anesthesiology, Anesthesia & Analgesia, the British Journal of Anaesthesia, and the Canadian Journal of Anesthesia.

Results

Three hundred thirteen articles (n = 313) were included in this review, with the following distribution by study design: 139 (44%) randomized controlled trials, 129 (41%) cohort studies, and 45 (15%) case-controlled, cross-sectional studies or systematic reviews. Overall, 96% (95% confidence interval: 91,100) of articles did not apply the PICOT approach in reporting the research question.

Conclusions

The PICOT approach may be helpful in defining and clearly stating the research question. It remains to be determined whether or not compliance with the PICOT style, or any other format for framing research questions, is associated with a higher quality of research reporting.
Literatur
1.
Zurück zum Zitat Casarett D, Karlawish JH, Sugarman J. Determining when quality improvement initiatives should be considered research: proposed criteria and potential implications. JAMA 2000; 283: 2275–80.PubMedCrossRef Casarett D, Karlawish JH, Sugarman J. Determining when quality improvement initiatives should be considered research: proposed criteria and potential implications. JAMA 2000; 283: 2275–80.PubMedCrossRef
2.
Zurück zum Zitat Sackett DL, Wennberg JE. Choosing the best research design for each question. BMJ 1997; 315: 1636.PubMed Sackett DL, Wennberg JE. Choosing the best research design for each question. BMJ 1997; 315: 1636.PubMed
3.
Zurück zum Zitat Posner MI. Cognition: an introduction. Glenview, IL: Scott Foresman; 1973. Posner MI. Cognition: an introduction. Glenview, IL: Scott Foresman; 1973.
4.
Zurück zum Zitat Clouse RE. Proposing a good research question: a simple formula for success. Gastrointest Endosc 2005; 61: 279–80.PubMedCrossRef Clouse RE. Proposing a good research question: a simple formula for success. Gastrointest Endosc 2005; 61: 279–80.PubMedCrossRef
5.
6.
Zurück zum Zitat Hulley SB, Cummings SR, Browner WS, Grady DG, Newman TB. Designing clinical research. 3rd ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2007. Hulley SB, Cummings SR, Browner WS, Grady DG, Newman TB. Designing clinical research. 3rd ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2007.
7.
Zurück zum Zitat Chulay M. Good research ideas for clinicians. AACN Adv Crit Care 2006; 17: 253–65.PubMed Chulay M. Good research ideas for clinicians. AACN Adv Crit Care 2006; 17: 253–65.PubMed
9.
Zurück zum Zitat Haynes RB, Sackett DL, Guyatt GH, Tugwell PS. Clinical epidemiology: how to do clinical practice research. 3rd ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2006. Haynes RB, Sackett DL, Guyatt GH, Tugwell PS. Clinical epidemiology: how to do clinical practice research. 3rd ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2006.
10.
11.
Zurück zum Zitat Beyea SC, Nicoll LH. Ten questions that will get you through any research report. AORN J 1997; 65: 978–9.PubMedCrossRef Beyea SC, Nicoll LH. Ten questions that will get you through any research report. AORN J 1997; 65: 978–9.PubMedCrossRef
12.
Zurück zum Zitat Mulrow CD, Cook D, American College of Physicians. Systematic reviews: synthesis of best evidence for health care decisions. Philadelphia, PA: American College of Physicians; 1998. Mulrow CD, Cook D, American College of Physicians. Systematic reviews: synthesis of best evidence for health care decisions. Philadelphia, PA: American College of Physicians; 1998.
13.
Zurück zum Zitat Cook DJ, Jaeschke R, Guyatt GH. Critical appraisal of therapeutic interventions in the intensive care unit: human monoclonal antibody treatment in sepsis. Journal Club of the Hamilton Regional Critical Care Group. J Intensive Care Med 1992; 7: 275–82.PubMed Cook DJ, Jaeschke R, Guyatt GH. Critical appraisal of therapeutic interventions in the intensive care unit: human monoclonal antibody treatment in sepsis. Journal Club of the Hamilton Regional Critical Care Group. J Intensive Care Med 1992; 7: 275–82.PubMed
14.
15.
Zurück zum Zitat Richardson WS, Wilson MC, Nishikawa J, Hayward RS. The well-built clinical question: a key to evidence-based decisions. ACP J Club 1995; 123: A12–3.PubMed Richardson WS, Wilson MC, Nishikawa J, Hayward RS. The well-built clinical question: a key to evidence-based decisions. ACP J Club 1995; 123: A12–3.PubMed
16.
Zurück zum Zitat Johnston L, Fineout-Overholt E. Teaching EBP: “Getting from zero to one.” Moving from recognizing and admitting uncertainties to asking searchable, answerable questions. Worldviews Evid Based Nurs 2005; 2: 98–102.PubMedCrossRef Johnston L, Fineout-Overholt E. Teaching EBP: “Getting from zero to one.” Moving from recognizing and admitting uncertainties to asking searchable, answerable questions. Worldviews Evid Based Nurs 2005; 2: 98–102.PubMedCrossRef
18.
Zurück zum Zitat Franco G, Monduzzi G. Experimental validation of the evidence-based occupational health paradigm and of the PICO model in the decision making process applied by occupational health physicians (Italian). Med Lav 2004; 95: 423–30.PubMed Franco G, Monduzzi G. Experimental validation of the evidence-based occupational health paradigm and of the PICO model in the decision making process applied by occupational health physicians (Italian). Med Lav 2004; 95: 423–30.PubMed
19.
Zurück zum Zitat Counsell C. Formulating questions and locating primary studies for inclusion in systematic reviews. Ann Intern Med 1997; 127: 380–7.PubMed Counsell C. Formulating questions and locating primary studies for inclusion in systematic reviews. Ann Intern Med 1997; 127: 380–7.PubMed
20.
Zurück zum Zitat Schardt C, Adams MB, Owens T, Keitz S, Fontelo P. Utilization of the PICO framework to improve searching PubMed for clinical questions. BMC Med Inform Decis Mak 2007; 7: 16.PubMedCrossRef Schardt C, Adams MB, Owens T, Keitz S, Fontelo P. Utilization of the PICO framework to improve searching PubMed for clinical questions. BMC Med Inform Decis Mak 2007; 7: 16.PubMedCrossRef
23.
Zurück zum Zitat Green SB, Byar DP. Using observational data from registries to compare treatments: the fallacy of omnimetrics. Stat Med 1984; 3: 361–73.PubMedCrossRef Green SB, Byar DP. Using observational data from registries to compare treatments: the fallacy of omnimetrics. Stat Med 1984; 3: 361–73.PubMedCrossRef
24.
Zurück zum Zitat Schlosser RW, Koul R, Costello J. Asking well-built questions for evidence-based practice in augmentative and alternative communication. J Commun Disord 2007; 40: 225–38.PubMedCrossRef Schlosser RW, Koul R, Costello J. Asking well-built questions for evidence-based practice in augmentative and alternative communication. J Commun Disord 2007; 40: 225–38.PubMedCrossRef
25.
Zurück zum Zitat West CP. Why do our questions matter? Adopt the PICOT approach. The Hospitalist 2005; 9: 32–4. West CP. Why do our questions matter? Adopt the PICOT approach. The Hospitalist 2005; 9: 32–4.
26.
Zurück zum Zitat Karkouti K, O’Farrell R, Yau TM, Beattie WS, Reducing Bleeding in Cardiac Surgery Research Group. Prediction of massive blood transfusion in cardiac surgery. Can J Anesth 2006; 53: 781–94.PubMedCrossRef Karkouti K, O’Farrell R, Yau TM, Beattie WS, Reducing Bleeding in Cardiac Surgery Research Group. Prediction of massive blood transfusion in cardiac surgery. Can J Anesth 2006; 53: 781–94.PubMedCrossRef
27.
Zurück zum Zitat Oshima T, Kasuya Y, Okumura Y, Murakami T, Dohi S. Identification of independent risk factors for fentanyl-induced cough. Can J Anesth 2006; 53: 753–8.PubMed Oshima T, Kasuya Y, Okumura Y, Murakami T, Dohi S. Identification of independent risk factors for fentanyl-induced cough. Can J Anesth 2006; 53: 753–8.PubMed
Metadaten
Titel
Posing the research question: not so simple
verfasst von
Lehana Thabane, PhD
Tara Thomas, MD
Chenglin Ye, BSc
James Paul, MD
Publikationsdatum
01.01.2009
Verlag
Springer-Verlag
Erschienen in
Canadian Journal of Anesthesia/Journal canadien d'anesthésie / Ausgabe 1/2009
Print ISSN: 0832-610X
Elektronische ISSN: 1496-8975
DOI
https://doi.org/10.1007/s12630-008-9007-4

Weitere Artikel der Ausgabe 1/2009

Canadian Journal of Anesthesia/Journal canadien d'anesthésie 1/2009 Zur Ausgabe

Akuter Schwindel: Wann lohnt sich eine MRT?

28.04.2024 Schwindel Nachrichten

Akuter Schwindel stellt oft eine diagnostische Herausforderung dar. Wie nützlich dabei eine MRT ist, hat eine Studie aus Finnland untersucht. Immerhin einer von sechs Patienten wurde mit akutem ischämischem Schlaganfall diagnostiziert.

Bei schweren Reaktionen auf Insektenstiche empfiehlt sich eine spezifische Immuntherapie

Insektenstiche sind bei Erwachsenen die häufigsten Auslöser einer Anaphylaxie. Einen wirksamen Schutz vor schweren anaphylaktischen Reaktionen bietet die allergenspezifische Immuntherapie. Jedoch kommt sie noch viel zu selten zum Einsatz.

Hinter dieser Appendizitis steckte ein Erreger

23.04.2024 Appendizitis Nachrichten

Schmerzen im Unterbauch, aber sonst nicht viel, was auf eine Appendizitis hindeutete: Ein junger Mann hatte Glück, dass trotzdem eine Laparoskopie mit Appendektomie durchgeführt und der Wurmfortsatz histologisch untersucht wurde.

Ärztliche Empathie hilft gegen Rückenschmerzen

23.04.2024 Leitsymptom Rückenschmerzen Nachrichten

Personen mit chronischen Rückenschmerzen, die von einfühlsamen Ärzten und Ärztinnen betreut werden, berichten über weniger Beschwerden und eine bessere Lebensqualität.

Update AINS

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.