Skip to main content
Erschienen in: American Journal of Clinical Dermatology 4/2018

01.08.2018 | Systematic Review

Acne Scarring Management: Systematic Review and Evaluation of the Evidence

verfasst von: Shashank Bhargava, Paulo R. Cunha, Jennifer Lee, George Kroumpouzos

Erschienen in: American Journal of Clinical Dermatology | Ausgabe 4/2018

Einloggen, um Zugang zu erhalten

Abstract

Background

Modalities for atrophic acne scarring can be classified depending upon the needs they satisfy; that is, resurfacing, lifting/volumization, tightening, or surgical removal/movement of tissue that is required for correction. A plethora of treatment options have resulted from the need to treat various acne scar types, variability of responses noted in various skin types, and increasing popularity of minimally invasive modalities. Still, there is a lack of consensus guidelines on treatment or combination therapies for various clinical scenarios.

Objective

This systematic review includes a critical evaluation of the evidence relevant to these modalities and various multimodality therapies.

Methods

We performed a systematic literature search in Medline and EMBASE databases for studies on acne scar management. Also, we checked the reference lists of included studies and review articles for further studies. A total of 89 studies were included in our quality of evidence evaluation.

Results

The efficacy of lasers and radiofrequency in atrophic acne scarring is confirmed by many comparative and observational studies. Other modalities can be used as an adjunct, the choice of which depends on the type, severity, and number of atrophic scars. Minimally invasive procedures, such as fractional radiofrequency and needling, provide good outcomes with negligible risks in patients with dark or sensitive skin types.

Conclusions

There is a lack of high-quality data. Fractional lasers and radiofrequency offer significant improvement in most types of atrophic acne scars with minimal risks and can be combined with all other treatment options. Combination therapies typically provide superior outcomes than solo treatments.
Literatur
1.
Zurück zum Zitat Layton AM, Henderson CA, Cunliffe WJ. A clinical evaluation of acne scarring and its incidence. Clin Exp Dermatol. 1994;19:303–8.PubMedCrossRef Layton AM, Henderson CA, Cunliffe WJ. A clinical evaluation of acne scarring and its incidence. Clin Exp Dermatol. 1994;19:303–8.PubMedCrossRef
2.
Zurück zum Zitat Rivera AE, Spencer JM. Clinical aspects of full-thickness wound healing. Clin Dermatol. 2007;25:39–48.PubMedCrossRef Rivera AE, Spencer JM. Clinical aspects of full-thickness wound healing. Clin Dermatol. 2007;25:39–48.PubMedCrossRef
3.
Zurück zum Zitat Koo J. The psychosocial impact of acne: patients’ perceptions. J Am Acad Dermatol. 1995;32:S26–30.PubMedCrossRef Koo J. The psychosocial impact of acne: patients’ perceptions. J Am Acad Dermatol. 1995;32:S26–30.PubMedCrossRef
4.
Zurück zum Zitat Halvorsen JA, Stern RS, Dalgard F, Thoresen M, Bjertness E, Lien L. Suicidal ideation, mental health problems, and social impairment are increased in adolescents with acne: a population-based study. J Invest Dermatol. 2011;131:363–70.PubMedCrossRef Halvorsen JA, Stern RS, Dalgard F, Thoresen M, Bjertness E, Lien L. Suicidal ideation, mental health problems, and social impairment are increased in adolescents with acne: a population-based study. J Invest Dermatol. 2011;131:363–70.PubMedCrossRef
5.
Zurück zum Zitat Werschler WP, Few JW, Jacob CI, Joseph JH, Spencer JM, Taub AF. Advancing the care of post-acne scarring: expert insights into new treatment options. J Drugs Dermatol. 2016;15:518–25.PubMed Werschler WP, Few JW, Jacob CI, Joseph JH, Spencer JM, Taub AF. Advancing the care of post-acne scarring: expert insights into new treatment options. J Drugs Dermatol. 2016;15:518–25.PubMed
6.
Zurück zum Zitat Jacob CI, Dover JS, Kaminer MS. Acne scarring: a classification system and review of treatment options. J Am Acad Dermatol. 2001;45:109–17.PubMedCrossRef Jacob CI, Dover JS, Kaminer MS. Acne scarring: a classification system and review of treatment options. J Am Acad Dermatol. 2001;45:109–17.PubMedCrossRef
7.
Zurück zum Zitat Goodman GJ, Baron JA. Postacne scarring-a qualitative global scarring grading system. J Cosmet Dermatol. 2006;5:48–52.PubMedCrossRef Goodman GJ, Baron JA. Postacne scarring-a qualitative global scarring grading system. J Cosmet Dermatol. 2006;5:48–52.PubMedCrossRef
8.
9.
Zurück zum Zitat Abdel Hay R, Shalaby K, Zaher H, Hafez V, Chi CC, Dimitri S, et al. Interventions for acne scars. Cochrane Database Syst Rev. 2016;4:CD011946.PubMed Abdel Hay R, Shalaby K, Zaher H, Hafez V, Chi CC, Dimitri S, et al. Interventions for acne scars. Cochrane Database Syst Rev. 2016;4:CD011946.PubMed
10.
Zurück zum Zitat Goodman GJ. Treating scars: addressing surface, volume, and movement to expedite optimal results. Part 2: more-severe grades of scarring. Dermatol Surg. 2012;38:1310–21.PubMedCrossRef Goodman GJ. Treating scars: addressing surface, volume, and movement to expedite optimal results. Part 2: more-severe grades of scarring. Dermatol Surg. 2012;38:1310–21.PubMedCrossRef
11.
12.
Zurück zum Zitat Linkner RV, Jim On S, Haddican M, Singer G, Shim-Chang H. Evaluating the efficacy of photodynamic therapy with 20% aminolevulinic acid and microdermabrasion as a combination treatment regimen for acne scarring: a split-face, randomized, double-blind pilot study. J Clin Aesthet Dermatol. 2014;7:32–5.PubMedPubMedCentral Linkner RV, Jim On S, Haddican M, Singer G, Shim-Chang H. Evaluating the efficacy of photodynamic therapy with 20% aminolevulinic acid and microdermabrasion as a combination treatment regimen for acne scarring: a split-face, randomized, double-blind pilot study. J Clin Aesthet Dermatol. 2014;7:32–5.PubMedPubMedCentral
13.
Zurück zum Zitat Bhalla M, Thami GP. Microdermabrasion: reappraisal and brief review of literature. Dermatol Surg. 2006;32:809–14.PubMed Bhalla M, Thami GP. Microdermabrasion: reappraisal and brief review of literature. Dermatol Surg. 2006;32:809–14.PubMed
14.
Zurück zum Zitat Cai GB, Li HD, Zhang Y, Liu L, Chen GY, Li TY, et al. Full face dermabrasion for acne scars [Chinese]. Zhonghua Zheng Xing Wai Ke Za Zhi. 2005;21:192–3.PubMed Cai GB, Li HD, Zhang Y, Liu L, Chen GY, Li TY, et al. Full face dermabrasion for acne scars [Chinese]. Zhonghua Zheng Xing Wai Ke Za Zhi. 2005;21:192–3.PubMed
15.
16.
Zurück zum Zitat Connolly D, Vu HL, Mariwalla K, Saedi N. Acne scarring–pathogenesis, evaluation, and treatment options. J Clin Aesthet Dermatol. 2017;10:12–3.PubMedPubMedCentral Connolly D, Vu HL, Mariwalla K, Saedi N. Acne scarring–pathogenesis, evaluation, and treatment options. J Clin Aesthet Dermatol. 2017;10:12–3.PubMedPubMedCentral
17.
Zurück zum Zitat Thiboutot D, Gollnick H, Bettoli V, Dreno B, Kang S, Leyden JJ, et al. New insights into the management of acne: an update from the global alliance to improve outcomes in acne group. J Am Acad Dermatol. 2009;60:S1–50.PubMedCrossRef Thiboutot D, Gollnick H, Bettoli V, Dreno B, Kang S, Leyden JJ, et al. New insights into the management of acne: an update from the global alliance to improve outcomes in acne group. J Am Acad Dermatol. 2009;60:S1–50.PubMedCrossRef
18.
Zurück zum Zitat Arora S. A study of efficacy of microdermabrasion in treatment of facial acne scars-Original Research. Int J Dent Med Spec. 2014;1:11–9.CrossRef Arora S. A study of efficacy of microdermabrasion in treatment of facial acne scars-Original Research. Int J Dent Med Spec. 2014;1:11–9.CrossRef
19.
Zurück zum Zitat Garg VK, Sinha S, Sarkar R. Glycolic acid peels versus salicylic-mandelic acid peels in active acne vulgaris and post-acne scarring and hyperpigmentation: a comparative study. Dermatol Surg. 2009;35:59–65.PubMed Garg VK, Sinha S, Sarkar R. Glycolic acid peels versus salicylic-mandelic acid peels in active acne vulgaris and post-acne scarring and hyperpigmentation: a comparative study. Dermatol Surg. 2009;35:59–65.PubMed
20.
Zurück zum Zitat Erbağci Z, Akçali C. Biweekly serial glycolic acid peels vs. long-term daily use of topical low-strength glycolic acid in the treatment of atrophic acne scars. Int J Dermatol. 2000;39:789–94.PubMedCrossRef Erbağci Z, Akçali C. Biweekly serial glycolic acid peels vs. long-term daily use of topical low-strength glycolic acid in the treatment of atrophic acne scars. Int J Dermatol. 2000;39:789–94.PubMedCrossRef
22.
Zurück zum Zitat Leheta TM, Abdel Hay RM, Hegazy RA, El Garem YF. Do combined alternating sessions of 1540 nm nonablative fractional laser and percutaneous collagen induction with trichloroacetic acid 20% show better results than each individual modality in the treatment of atrophic acne scars? A randomized controlled trial. J Dermatol Treat. 2014;25:137–41.CrossRef Leheta TM, Abdel Hay RM, Hegazy RA, El Garem YF. Do combined alternating sessions of 1540 nm nonablative fractional laser and percutaneous collagen induction with trichloroacetic acid 20% show better results than each individual modality in the treatment of atrophic acne scars? A randomized controlled trial. J Dermatol Treat. 2014;25:137–41.CrossRef
23.
Zurück zum Zitat Park JH, Choi YD, Kim SW, Kim YC, Park SW. Effectiveness of modified phenol peel (Exoderm) on facial wrinkles, acne scars and other skin problems of Asian patients. J Dermatol. 2007;34:17–24.PubMedCrossRef Park JH, Choi YD, Kim SW, Kim YC, Park SW. Effectiveness of modified phenol peel (Exoderm) on facial wrinkles, acne scars and other skin problems of Asian patients. J Dermatol. 2007;34:17–24.PubMedCrossRef
24.
Zurück zum Zitat Leheta TM, Abdel Hay RM, Garem YF. Deep peeling using phenol versus percutaneous collagen induction combined with trichloroacetic acid 20% in atrophic post-acne scars; a randomized controlled trial. J Dermatolog Treat. 2014;25:130–6.PubMedCrossRef Leheta TM, Abdel Hay RM, Garem YF. Deep peeling using phenol versus percutaneous collagen induction combined with trichloroacetic acid 20% in atrophic post-acne scars; a randomized controlled trial. J Dermatolog Treat. 2014;25:130–6.PubMedCrossRef
25.
Zurück zum Zitat Al-Waiz MM, Al-Sharqi AI. Medium-depth chemical peels in the treatment acne scars in dark-skinned individuals. Dermatol Surg. 2002;28:383–7.PubMed Al-Waiz MM, Al-Sharqi AI. Medium-depth chemical peels in the treatment acne scars in dark-skinned individuals. Dermatol Surg. 2002;28:383–7.PubMed
26.
Zurück zum Zitat Lee JB, Chung WG, Kwahck H, Lee KH. Focal treatment of acne scars with trichloroacetic acid: chemical reconstruction of skin scars method. Dermatol Surg. 2002;28:1017–21.PubMed Lee JB, Chung WG, Kwahck H, Lee KH. Focal treatment of acne scars with trichloroacetic acid: chemical reconstruction of skin scars method. Dermatol Surg. 2002;28:1017–21.PubMed
27.
Zurück zum Zitat Yug A, Lane JE, Howard MS, Kent DE. Histologic study of depressed acne scars treated with serial high-concentration (95%) trichloroacetic acid. Dermatol Surg. 2006;32:985–90.PubMed Yug A, Lane JE, Howard MS, Kent DE. Histologic study of depressed acne scars treated with serial high-concentration (95%) trichloroacetic acid. Dermatol Surg. 2006;32:985–90.PubMed
28.
Zurück zum Zitat Agrawal N, Gupta LK, Khare AK, Kuldeep CM, Mittal A. Therapeutic response of 70% trichloroacetic acid CROSS in atrophic acne scars. Dermatol Surg. 2015;41:597–604.CrossRef Agrawal N, Gupta LK, Khare AK, Kuldeep CM, Mittal A. Therapeutic response of 70% trichloroacetic acid CROSS in atrophic acne scars. Dermatol Surg. 2015;41:597–604.CrossRef
29.
Zurück zum Zitat Khunger N, Bhardwaj D, Khunger M. Evaluation of CROSS technique with 100% TCA in the management of ice pick acne scars in darker skin types. J Cosmet Dermatol. 2011;10:51–7.PubMedCrossRef Khunger N, Bhardwaj D, Khunger M. Evaluation of CROSS technique with 100% TCA in the management of ice pick acne scars in darker skin types. J Cosmet Dermatol. 2011;10:51–7.PubMedCrossRef
30.
Zurück zum Zitat Ahmed R, Mohammed G, Ismail N, Elakhras A. Randomized clinical trial of CO2 LASER pinpoint irradiation technique versus chemical reconstruction of skin scars (CROSS) in treating ice pick acne scars. J Cosmet Laser Ther. 2014;16:8–13.PubMedCrossRef Ahmed R, Mohammed G, Ismail N, Elakhras A. Randomized clinical trial of CO2 LASER pinpoint irradiation technique versus chemical reconstruction of skin scars (CROSS) in treating ice pick acne scars. J Cosmet Laser Ther. 2014;16:8–13.PubMedCrossRef
31.
Zurück zum Zitat Fabbrocini G, Fardella N, Monfrecola A, Proietti I, Innocenzi D. Acne scarring treatment using skin needling. Clin Exp Dermatol. 2009;34:874–7.PubMedCrossRef Fabbrocini G, Fardella N, Monfrecola A, Proietti I, Innocenzi D. Acne scarring treatment using skin needling. Clin Exp Dermatol. 2009;34:874–7.PubMedCrossRef
32.
Zurück zum Zitat Majid I. Microneedling therapy in atrophic facial scars: an objective assessment. J Cutan Asthet Surg. 2009;2:26–30.CrossRef Majid I. Microneedling therapy in atrophic facial scars: an objective assessment. J Cutan Asthet Surg. 2009;2:26–30.CrossRef
33.
Zurück zum Zitat Pandey A, Swain JP, Minj A. Assessment of microneedling therapy in the management of atrophic facial acne scars. J Evid Based Med Healthc. 2015;57:8911–3.CrossRef Pandey A, Swain JP, Minj A. Assessment of microneedling therapy in the management of atrophic facial acne scars. J Evid Based Med Healthc. 2015;57:8911–3.CrossRef
34.
Zurück zum Zitat Srivastava R, Shah YM, Garg AM, Paliwal G, Kumar A. A study of skin resurfacing for atrophic acne scars by skin needling with dermaroller. Internat Med J. 2016;3:1010–4. Srivastava R, Shah YM, Garg AM, Paliwal G, Kumar A. A study of skin resurfacing for atrophic acne scars by skin needling with dermaroller. Internat Med J. 2016;3:1010–4.
35.
Zurück zum Zitat Dogra S, Yadav S, Sarangal R. Microneedling for acne scars in Asian skin type: an effective low cost treatment modality. J Cosmet Dermatol. 2014;13:180–7.PubMedCrossRef Dogra S, Yadav S, Sarangal R. Microneedling for acne scars in Asian skin type: an effective low cost treatment modality. J Cosmet Dermatol. 2014;13:180–7.PubMedCrossRef
36.
Zurück zum Zitat Alam M, Han S, Pongprutthipan M, Disphanurat W, Kakar R, Nodzenski M, et al. Efficacy of a needling device for the treatment of acne scars: a randomized clinical trial. JAMA Dermatol. 2014;150:844–9.PubMedCrossRef Alam M, Han S, Pongprutthipan M, Disphanurat W, Kakar R, Nodzenski M, et al. Efficacy of a needling device for the treatment of acne scars: a randomized clinical trial. JAMA Dermatol. 2014;150:844–9.PubMedCrossRef
37.
Zurück zum Zitat Leheta T, El Tawdy A, Abdel Hay R, Farid S. Percutaneous collagen induction versus full-concentration trichloroacetic acid in the treatment of atrophic acne scars. Dermatol Surg. 2011;37:207–16.PubMedCrossRef Leheta T, El Tawdy A, Abdel Hay R, Farid S. Percutaneous collagen induction versus full-concentration trichloroacetic acid in the treatment of atrophic acne scars. Dermatol Surg. 2011;37:207–16.PubMedCrossRef
38.
Zurück zum Zitat Asif M, Kanodia S, Singh K. Combined autologous platelet-rich plasma with microneedling versus microneedling with distilled water in the treatment of atrophic acne scars: a concurrent split-face study. J Cosmet Dermatol. 2016;15:434–43.PubMedCrossRef Asif M, Kanodia S, Singh K. Combined autologous platelet-rich plasma with microneedling versus microneedling with distilled water in the treatment of atrophic acne scars: a concurrent split-face study. J Cosmet Dermatol. 2016;15:434–43.PubMedCrossRef
39.
Zurück zum Zitat Fabbrocini G, De Vita V, Pastore F, Panariello F, Fardella N, Sepulveres R, et al. Combined use of skin needling and platelet-rich plasma in acne scarring treatment. Cosm Dermat. 2011;24:177–83. Fabbrocini G, De Vita V, Pastore F, Panariello F, Fardella N, Sepulveres R, et al. Combined use of skin needling and platelet-rich plasma in acne scarring treatment. Cosm Dermat. 2011;24:177–83.
40.
Zurück zum Zitat Cachafeiro T, Escobar G, Maldonado G, Cestari T, Corleta O. Comparison of nonablative fractional Erbium laser 1,340 nm and microneedling for the treatment of atrophic acne scars: a randomized clinical trial. Dermatol Surg. 2016;42:232–41.PubMedCrossRef Cachafeiro T, Escobar G, Maldonado G, Cestari T, Corleta O. Comparison of nonablative fractional Erbium laser 1,340 nm and microneedling for the treatment of atrophic acne scars: a randomized clinical trial. Dermatol Surg. 2016;42:232–41.PubMedCrossRef
41.
Zurück zum Zitat Walia S, Alster TS. Prolonged clinical and histologic effects from CO2 laser resurfacing of atrophic acne scars. Dermatol Surg. 1999;25:926–30.PubMedCrossRef Walia S, Alster TS. Prolonged clinical and histologic effects from CO2 laser resurfacing of atrophic acne scars. Dermatol Surg. 1999;25:926–30.PubMedCrossRef
42.
Zurück zum Zitat Koo SH, Yoon ES, Ahn DS, Park SH. Laser punch out for acne scars. Aesthetic Plast Surg. 2001;25:46–51.PubMedCrossRef Koo SH, Yoon ES, Ahn DS, Park SH. Laser punch out for acne scars. Aesthetic Plast Surg. 2001;25:46–51.PubMedCrossRef
43.
Zurück zum Zitat Kye YC. Resurfacing of pitted facial scars with a pulsed Er:YAG laser. Dermatol Surg. 1997;23:685–7. Kye YC. Resurfacing of pitted facial scars with a pulsed Er:YAG laser. Dermatol Surg. 1997;23:685–7.
44.
Zurück zum Zitat Hu S, Gold MH. Treatment of facial acne scars in Asian skin with the single-spot, 2940-nm Er:YAG dual-mode laser. J Drugs Dermatol. 2010;9:1341–4.PubMed Hu S, Gold MH. Treatment of facial acne scars in Asian skin with the single-spot, 2940-nm Er:YAG dual-mode laser. J Drugs Dermatol. 2010;9:1341–4.PubMed
45.
Zurück zum Zitat Wanitphakdeedecha R, Manuskiatti W, Siriphukpong S, Chen TM. Treatment of punched out atrophic and rolling acne scars in skin phototypes iii, iv, and v with variable square pulse Erbium:yttrium-aluminum-garnet laser resurfacing. Dermatol Surg. 2009;35:1376–83.PubMedCrossRef Wanitphakdeedecha R, Manuskiatti W, Siriphukpong S, Chen TM. Treatment of punched out atrophic and rolling acne scars in skin phototypes iii, iv, and v with variable square pulse Erbium:yttrium-aluminum-garnet laser resurfacing. Dermatol Surg. 2009;35:1376–83.PubMedCrossRef
46.
Zurück zum Zitat Woo SH, Park JH, Kye YC. Resurfacing of different types of facial acne scar with short-pulsed, variable-pulsed, and dual-mode Er: Yag laser. Dermatol Surg. 2004;30:488–93.PubMed Woo SH, Park JH, Kye YC. Resurfacing of different types of facial acne scar with short-pulsed, variable-pulsed, and dual-mode Er: Yag laser. Dermatol Surg. 2004;30:488–93.PubMed
47.
Zurück zum Zitat Tanzi EL, Alster TS. Treatment of atrophic facial acne scars with dual-mode Er:YAG laser. Dermatol Surg. 2002;28:551–5.PubMed Tanzi EL, Alster TS. Treatment of atrophic facial acne scars with dual-mode Er:YAG laser. Dermatol Surg. 2002;28:551–5.PubMed
48.
Zurück zum Zitat Tanzi EL, Alster TS. Single-pass carbon dioxide versus multiple-pass Er:YAG laser skin resurfacing: a comparison of postoperative wound healing and side-effect rates. Dermatol Surg. 2003;29:80–4.PubMed Tanzi EL, Alster TS. Single-pass carbon dioxide versus multiple-pass Er:YAG laser skin resurfacing: a comparison of postoperative wound healing and side-effect rates. Dermatol Surg. 2003;29:80–4.PubMed
49.
Zurück zum Zitat Jeong JT, Kye YC. Resurfacing of pitted facial acne scars with a long-pulsed Er:YAG laser. Dermatol Surg. 2001;27:107–10.PubMed Jeong JT, Kye YC. Resurfacing of pitted facial acne scars with a long-pulsed Er:YAG laser. Dermatol Surg. 2001;27:107–10.PubMed
50.
Zurück zum Zitat Orentreich DS, Orentreich N. Subcutaneous incisionless (subcision) surgery for the correction of depressed scars and wrinkles. Dermatol Surg. 1995;21:543–9.PubMed Orentreich DS, Orentreich N. Subcutaneous incisionless (subcision) surgery for the correction of depressed scars and wrinkles. Dermatol Surg. 1995;21:543–9.PubMed
51.
Zurück zum Zitat Nilforoushzadeh M, Lotv E, Nickkholgh E. Can subcision with the cannula be an acceptable alternative method in treatment of acne scars? Med Arch. 2015;69:384–6.PubMedPubMedCentralCrossRef Nilforoushzadeh M, Lotv E, Nickkholgh E. Can subcision with the cannula be an acceptable alternative method in treatment of acne scars? Med Arch. 2015;69:384–6.PubMedPubMedCentralCrossRef
52.
Zurück zum Zitat Alam M, Omura N, Kaminer MS. Subcision for acne scarring: technique and outcomes in 40 patients. Dermatol Surg. 2005;31:310–7.PubMedCrossRef Alam M, Omura N, Kaminer MS. Subcision for acne scarring: technique and outcomes in 40 patients. Dermatol Surg. 2005;31:310–7.PubMedCrossRef
53.
Zurück zum Zitat Aalami HS, Balighi K, Lajevardi V, Akbari E. Subcision-suction method: a new successful combination therapy in treatment of atrophic acne scars and other depressed scars. J Eur Acad Dermatol Venereol. 2011;25:92–9.CrossRef Aalami HS, Balighi K, Lajevardi V, Akbari E. Subcision-suction method: a new successful combination therapy in treatment of atrophic acne scars and other depressed scars. J Eur Acad Dermatol Venereol. 2011;25:92–9.CrossRef
54.
Zurück zum Zitat Kandil AH, Selim AG, Elghonemy S, Eldosoky F, Elsayed A. Evaluation of subcision-suction method in the treatment of depressed scars. Egypt J Plast Reconstr Surg. 2016;40:39–48. Kandil AH, Selim AG, Elghonemy S, Eldosoky F, Elsayed A. Evaluation of subcision-suction method in the treatment of depressed scars. Egypt J Plast Reconstr Surg. 2016;40:39–48.
55.
Zurück zum Zitat Lee JW, Kim BJ, Kim MN. Treatment of acne scars using subdermal minimal surgery technology. Dermatol Surg. 2010;36:1281–7.PubMedCrossRef Lee JW, Kim BJ, Kim MN. Treatment of acne scars using subdermal minimal surgery technology. Dermatol Surg. 2010;36:1281–7.PubMedCrossRef
56.
Zurück zum Zitat Wang F, Garza LA, Kang S, Varani J, Orringer JS, Fisher GJ, et al. In vivo stimulation of de novo collagen production caused by cross-linked hyaluronic acid dermal filler injections in photodamaged human skin. Arch Dermatol. 2007;143:155–63.PubMed Wang F, Garza LA, Kang S, Varani J, Orringer JS, Fisher GJ, et al. In vivo stimulation of de novo collagen production caused by cross-linked hyaluronic acid dermal filler injections in photodamaged human skin. Arch Dermatol. 2007;143:155–63.PubMed
57.
Zurück zum Zitat Goodman GJ. Management of post-acne scarring: what are the options for treatment? Am J Clin Dermatol. 2000;1:3–17.PubMedCrossRef Goodman GJ. Management of post-acne scarring: what are the options for treatment? Am J Clin Dermatol. 2000;1:3–17.PubMedCrossRef
58.
Zurück zum Zitat Goldberg DJ, Amin S, Hussain M. Acne scar correction using calcium hydroxylapatite in a carrier-based gel. J Cosmet Laser Ther. 2006;8:134–6.PubMedCrossRef Goldberg DJ, Amin S, Hussain M. Acne scar correction using calcium hydroxylapatite in a carrier-based gel. J Cosmet Laser Ther. 2006;8:134–6.PubMedCrossRef
60.
Zurück zum Zitat Sapra S, Stewart JA, Mraud K, Schupp R. A Canadian study of the use of poly-L-lactic acid dermal implant for the treatment of hill and valley acne scarring. Dermatol Surg. 2015;41:587–94.PubMedCrossRef Sapra S, Stewart JA, Mraud K, Schupp R. A Canadian study of the use of poly-L-lactic acid dermal implant for the treatment of hill and valley acne scarring. Dermatol Surg. 2015;41:587–94.PubMedCrossRef
61.
Zurück zum Zitat Sadove R. Injectable poly-L-lactic acid: A novel sculpting agent for the treatment of dermal fat atrophy after severe acne. Aesthetic Plast Surg. 2009;33:113–6.PubMedCrossRef Sadove R. Injectable poly-L-lactic acid: A novel sculpting agent for the treatment of dermal fat atrophy after severe acne. Aesthetic Plast Surg. 2009;33:113–6.PubMedCrossRef
62.
Zurück zum Zitat Karnik J, Baumann L, Bruce S. A double-blind, randomized, multicenter, controlled trial of suspended polymethylmethacrylate microspheres for the correction of atrophic facial acne scars. J Am Acad Dermatol. 2014;71:77–83.PubMedCrossRef Karnik J, Baumann L, Bruce S. A double-blind, randomized, multicenter, controlled trial of suspended polymethylmethacrylate microspheres for the correction of atrophic facial acne scars. J Am Acad Dermatol. 2014;71:77–83.PubMedCrossRef
63.
Zurück zum Zitat Epstein RE, Spencer JM. Correction of atrophic scars with artefill: an open-label pilot study. J Drugs Dermatol. 2010;9:1062–4.PubMed Epstein RE, Spencer JM. Correction of atrophic scars with artefill: an open-label pilot study. J Drugs Dermatol. 2010;9:1062–4.PubMed
64.
Zurück zum Zitat Sage RJ, Lopiccolo MC, Liu A, Mahmoud BH, Tierney EP, Kouba DJ. Subcuticular incision versus naturally sourced porcine collagen filler for acne scars: a randomized splitface comparison. Dermatol Surg. 2011;37:426–31.PubMedCrossRef Sage RJ, Lopiccolo MC, Liu A, Mahmoud BH, Tierney EP, Kouba DJ. Subcuticular incision versus naturally sourced porcine collagen filler for acne scars: a randomized splitface comparison. Dermatol Surg. 2011;37:426–31.PubMedCrossRef
65.
Zurück zum Zitat Shilpa K, Sacchidanand S, Leelavathy B, Shilpashree P, Gorur D, Ranjitha R, et al. Outcome of dermal grafting in the management of atrophic facial scars. J Cutan Aesthet Surg. 2016;9:244–8.PubMedPubMedCentralCrossRef Shilpa K, Sacchidanand S, Leelavathy B, Shilpashree P, Gorur D, Ranjitha R, et al. Outcome of dermal grafting in the management of atrophic facial scars. J Cutan Aesthet Surg. 2016;9:244–8.PubMedPubMedCentralCrossRef
66.
Zurück zum Zitat Azzam OA, Atta AT, Sobhi RM, Mostafa PI. Fractional CO2 laser treatment vs autologous fat transfer in the treatment of acne scars: a comparative study. J Drugs Dermatol. 2013;12:e7–13.PubMed Azzam OA, Atta AT, Sobhi RM, Mostafa PI. Fractional CO2 laser treatment vs autologous fat transfer in the treatment of acne scars: a comparative study. J Drugs Dermatol. 2013;12:e7–13.PubMed
67.
Zurück zum Zitat Gu Z, Li Y, Li H. Use of condensed nanofat combined with fat grafts to treat atrophic scars. JAMA Facial Plast Surg. 2018;20:128–35.PubMedCrossRef Gu Z, Li Y, Li H. Use of condensed nanofat combined with fat grafts to treat atrophic scars. JAMA Facial Plast Surg. 2018;20:128–35.PubMedCrossRef
68.
Zurück zum Zitat Chawla S. Split face comparative study of microneedling with PRP versus microneedling with vitamin C in treating atrophic post acne scars. J Cutan Aesthet Surg. 2014;7:209–12.PubMedPubMedCentralCrossRef Chawla S. Split face comparative study of microneedling with PRP versus microneedling with vitamin C in treating atrophic post acne scars. J Cutan Aesthet Surg. 2014;7:209–12.PubMedPubMedCentralCrossRef
69.
Zurück zum Zitat Tenna S, Cogliandro A, Barone M, Panasiti V, Tirindelli M, Nobile C, et al. Comparative study using autologous fat grafts plus platelet-rich plasma with or without fractional CO2 laser resurfacing in treatment of acne scars: analysis of outcomes and satisfaction with FACE-Q. Aesthetic Plast Surg. 2017;41:661–6.PubMedCrossRef Tenna S, Cogliandro A, Barone M, Panasiti V, Tirindelli M, Nobile C, et al. Comparative study using autologous fat grafts plus platelet-rich plasma with or without fractional CO2 laser resurfacing in treatment of acne scars: analysis of outcomes and satisfaction with FACE-Q. Aesthetic Plast Surg. 2017;41:661–6.PubMedCrossRef
70.
Zurück zum Zitat Zhu JT, Xuan M, Zhang YN, Liu HW, Cai JH, Wu YH, et al. The efficacy of autologous platelet-rich plasma combined with erbium fractional laser therapy for facial acne scars or acne. Mol Med Rep. 2013;8:233–7.PubMedCrossRef Zhu JT, Xuan M, Zhang YN, Liu HW, Cai JH, Wu YH, et al. The efficacy of autologous platelet-rich plasma combined with erbium fractional laser therapy for facial acne scars or acne. Mol Med Rep. 2013;8:233–7.PubMedCrossRef
71.
Zurück zum Zitat Lee JW, Kim BJ, Kim MN, Mun SK. The efficacy of autologous platelet rich plasma combined with ablative carbon dioxide fractional resurfacing for acne scars: a simultaneous split-face trial. Dermatol Surg. 2011;37:931–8.PubMedCrossRef Lee JW, Kim BJ, Kim MN, Mun SK. The efficacy of autologous platelet rich plasma combined with ablative carbon dioxide fractional resurfacing for acne scars: a simultaneous split-face trial. Dermatol Surg. 2011;37:931–8.PubMedCrossRef
72.
Zurück zum Zitat Gawdat HI, Hegazy RA, Fawzy MM, Fathy M. Autologous platelet rich plasma: topical versus intradermal after fractional ablative carbon dioxide laser treatment of atrophic acne scars. Dermatol Surg. 2014;40:152–6.PubMedCrossRef Gawdat HI, Hegazy RA, Fawzy MM, Fathy M. Autologous platelet rich plasma: topical versus intradermal after fractional ablative carbon dioxide laser treatment of atrophic acne scars. Dermatol Surg. 2014;40:152–6.PubMedCrossRef
73.
Zurück zum Zitat Faghihi G, Keyvan S, Asilian A, Nouraei S, Behfar S, Nilforoushzadeh MA. Efficacy of autologous platelet-rich plasma combined with fractional ablative carbon dioxide resurfacing laser in treatment of facial atrophic acne scars: a split-face randomized clinical trial. Ind J Dermatol Venereol Leprol. 2016;82:162–8.CrossRef Faghihi G, Keyvan S, Asilian A, Nouraei S, Behfar S, Nilforoushzadeh MA. Efficacy of autologous platelet-rich plasma combined with fractional ablative carbon dioxide resurfacing laser in treatment of facial atrophic acne scars: a split-face randomized clinical trial. Ind J Dermatol Venereol Leprol. 2016;82:162–8.CrossRef
75.
Zurück zum Zitat Manuskiatti W, Iamphonrat T, Wanitphakdeedecha R, Eimpunth S. Comparison of fractional erbium-doped yttrium aluminum garnet and carbon dioxide lasers in resurfacing of atrophic acne scars in Asians. Dermatol Surg. 2013;39:111–20.PubMedCrossRef Manuskiatti W, Iamphonrat T, Wanitphakdeedecha R, Eimpunth S. Comparison of fractional erbium-doped yttrium aluminum garnet and carbon dioxide lasers in resurfacing of atrophic acne scars in Asians. Dermatol Surg. 2013;39:111–20.PubMedCrossRef
76.
Zurück zum Zitat Walgrave SE, Ortiz AE, MacFalls HT, Elkeeb L, Truitt AK, Tournas JA, et al. Evaluation of a novel fractional resurfacing device for treatment of acne scarring. Lasers Surg Med. 2009;41:122–7.PubMedCrossRef Walgrave SE, Ortiz AE, MacFalls HT, Elkeeb L, Truitt AK, Tournas JA, et al. Evaluation of a novel fractional resurfacing device for treatment of acne scarring. Lasers Surg Med. 2009;41:122–7.PubMedCrossRef
77.
Zurück zum Zitat Cho SB, Lee SJ, Kang JM. The efficacy and safety of 10,600-nm carbon dioxide fractional laser for acne scars in Asian patients. Dermatol Surg. 2009;35:1955–61.PubMedCrossRef Cho SB, Lee SJ, Kang JM. The efficacy and safety of 10,600-nm carbon dioxide fractional laser for acne scars in Asian patients. Dermatol Surg. 2009;35:1955–61.PubMedCrossRef
78.
Zurück zum Zitat Alajlan AM, Alsuwaidan SN. Acne scars in ethnic skin treated with both non-ablative fractional 1,550 nm and ablative fractional CO2 lasers: comparative retrospective analysis with recommended guidelines. Lasers Surg Med. 2011;43:787–91.PubMedCrossRef Alajlan AM, Alsuwaidan SN. Acne scars in ethnic skin treated with both non-ablative fractional 1,550 nm and ablative fractional CO2 lasers: comparative retrospective analysis with recommended guidelines. Lasers Surg Med. 2011;43:787–91.PubMedCrossRef
79.
Zurück zum Zitat Naouri M, Atlan M, Perrodeau E, Georgesco G, Khallouf R, Martin L, et al. High-resolution ultrasound imaging to demonstrate and predict efficacy of carbon dioxide fractional resurfacing laser treatment. Dermatol Surg. 2011;37:596–603.PubMedCrossRef Naouri M, Atlan M, Perrodeau E, Georgesco G, Khallouf R, Martin L, et al. High-resolution ultrasound imaging to demonstrate and predict efficacy of carbon dioxide fractional resurfacing laser treatment. Dermatol Surg. 2011;37:596–603.PubMedCrossRef
80.
Zurück zum Zitat Qian H, Lu Z, Ding H, Yan S, Xiang L, Gold MH. Treatment of acne scarring with fractional CO2 laser. J Cosmet Laser Ther. 2012;14:162–5.PubMedCrossRef Qian H, Lu Z, Ding H, Yan S, Xiang L, Gold MH. Treatment of acne scarring with fractional CO2 laser. J Cosmet Laser Ther. 2012;14:162–5.PubMedCrossRef
81.
Zurück zum Zitat Zhang Z, Fei Y, Chen X, Lu W, Chen J. Comparison of a fractional microplasma radio frequency technology and carbon dioxide fractional laser for the treatment of atrophic acne scars: a randomized split-face clinical study. Dermatol Surg. 2013;39:559–66.PubMedCrossRef Zhang Z, Fei Y, Chen X, Lu W, Chen J. Comparison of a fractional microplasma radio frequency technology and carbon dioxide fractional laser for the treatment of atrophic acne scars: a randomized split-face clinical study. Dermatol Surg. 2013;39:559–66.PubMedCrossRef
82.
Zurück zum Zitat Huang L. A new modality for fractional CO2 laser resurfacing for acne scars in Asians. Lasers Med Sci. 2013;28:627–32.PubMedCrossRef Huang L. A new modality for fractional CO2 laser resurfacing for acne scars in Asians. Lasers Med Sci. 2013;28:627–32.PubMedCrossRef
83.
Zurück zum Zitat Asilian A, Salimi E, Faghihi G. Comparison of Q-switched 1064-nm Nd: YAG laser and fractional CO2 laser efficacies on improvement of atrophic facial acne scar. J Res Med Sci. 2011;16:1189–95.PubMedPubMedCentral Asilian A, Salimi E, Faghihi G. Comparison of Q-switched 1064-nm Nd: YAG laser and fractional CO2 laser efficacies on improvement of atrophic facial acne scar. J Res Med Sci. 2011;16:1189–95.PubMedPubMedCentral
84.
Zurück zum Zitat Elcin G, Yalici-Armagan B. Fractional carbon dioxide laser for the treatment of facial atrophic acne scars: prospective clinical trial with short and long-term evaluation. Lasers Med Sci. 2017;32:2047–54.PubMedCrossRef Elcin G, Yalici-Armagan B. Fractional carbon dioxide laser for the treatment of facial atrophic acne scars: prospective clinical trial with short and long-term evaluation. Lasers Med Sci. 2017;32:2047–54.PubMedCrossRef
85.
Zurück zum Zitat Ortiz AE, Tremaine AM, Zachary CB. Long-term efficacy of fractional resurfacing device. Lasers Surg Med. 2010;42:168–70.PubMedCrossRef Ortiz AE, Tremaine AM, Zachary CB. Long-term efficacy of fractional resurfacing device. Lasers Surg Med. 2010;42:168–70.PubMedCrossRef
86.
Zurück zum Zitat Chapas AM, Brightman L, Sukal S. Successful treatment of acneiform scarring with CO2 ablative fractional resurfacing. Lasers Surg Med. 2008;40:381–6.PubMedCrossRef Chapas AM, Brightman L, Sukal S. Successful treatment of acneiform scarring with CO2 ablative fractional resurfacing. Lasers Surg Med. 2008;40:381–6.PubMedCrossRef
87.
Zurück zum Zitat Park GH, Rhee DY, Bak H, Chang SE, Lee MW, Choi JH, et al. Treatment of atrophic scars and fractional photothermolysis: short-term follow-up. J Dermatolog Treat. 2011;22:43–8.PubMedCrossRef Park GH, Rhee DY, Bak H, Chang SE, Lee MW, Choi JH, et al. Treatment of atrophic scars and fractional photothermolysis: short-term follow-up. J Dermatolog Treat. 2011;22:43–8.PubMedCrossRef
88.
Zurück zum Zitat Magnani LR, Schweiger ES. Fractional CO2 lasers for the treatment of atrophic acne scars: a review of the literature. J Cosmet Laser Ther. 2014;16:48–56.PubMedCrossRef Magnani LR, Schweiger ES. Fractional CO2 lasers for the treatment of atrophic acne scars: a review of the literature. J Cosmet Laser Ther. 2014;16:48–56.PubMedCrossRef
89.
Zurück zum Zitat Chan NP, Ho SG, Yeung CK, Shek SY, Chan HH. The use of non-ablative fractional resurfacing in Asian acne scar patients. Lasers Surg Med. 2010;42:710–5.PubMed Chan NP, Ho SG, Yeung CK, Shek SY, Chan HH. The use of non-ablative fractional resurfacing in Asian acne scar patients. Lasers Surg Med. 2010;42:710–5.PubMed
90.
Zurück zum Zitat Deng H, Yuan D, Yan C, Lin X, Ding X. A 2940 nm fractional photothermolysis laser in the treatment of acne scarring: a pilot study in China. J Drugs Dermatol. 2009;8:978–80.PubMed Deng H, Yuan D, Yan C, Lin X, Ding X. A 2940 nm fractional photothermolysis laser in the treatment of acne scarring: a pilot study in China. J Drugs Dermatol. 2009;8:978–80.PubMed
91.
Zurück zum Zitat Nirmal B, Sripathi H, Rao R, Prabhu S, Kudur MH, et al. Efficacy and safety of erbium-doped yttrium aluminium garnet fractional resurfacing laser for treatment of facial acne scars. Indian J Dermatol Venereol Leprol. 2013;79:193–8.PubMedCrossRef Nirmal B, Sripathi H, Rao R, Prabhu S, Kudur MH, et al. Efficacy and safety of erbium-doped yttrium aluminium garnet fractional resurfacing laser for treatment of facial acne scars. Indian J Dermatol Venereol Leprol. 2013;79:193–8.PubMedCrossRef
92.
Zurück zum Zitat Kim S. Treatment of acne scars in Asian patients using a 2,790-nm fractional yttrium scandium gallium garnet laser. Dermatol Surg. 2011;37:1464–9.PubMedCrossRef Kim S. Treatment of acne scars in Asian patients using a 2,790-nm fractional yttrium scandium gallium garnet laser. Dermatol Surg. 2011;37:1464–9.PubMedCrossRef
93.
Zurück zum Zitat Gokalp H. Evaluation of nonablative fractional laser treatment in scar reduction. Lasers Med Sci. 2017;32:1629–35.PubMedCrossRef Gokalp H. Evaluation of nonablative fractional laser treatment in scar reduction. Lasers Med Sci. 2017;32:1629–35.PubMedCrossRef
94.
Zurück zum Zitat Yang Q, Huang W, Qian H, Chen S, Ma L, Lu Z. Efficacy and safety of 1550-nm fractional laser in the treatment of acne scars in Chinese patients: a split-face comparative study. J Cosmet Laser Ther. 2016;18:312–6.PubMedCrossRef Yang Q, Huang W, Qian H, Chen S, Ma L, Lu Z. Efficacy and safety of 1550-nm fractional laser in the treatment of acne scars in Chinese patients: a split-face comparative study. J Cosmet Laser Ther. 2016;18:312–6.PubMedCrossRef
95.
Zurück zum Zitat Chrastil B, Glaich AS, Goldberg LH, Friedman PM. Second-generation 1,550-nm fractional photothermolysis for the treatment of acne scars. Dermatol Surg. 2008;34:1327–32.PubMed Chrastil B, Glaich AS, Goldberg LH, Friedman PM. Second-generation 1,550-nm fractional photothermolysis for the treatment of acne scars. Dermatol Surg. 2008;34:1327–32.PubMed
96.
Zurück zum Zitat Chae WS, Seong JY, Jung HN, Kong SH, Kim MH, Suh HS, et al. Comparative study on efficacy and safety of 1550 nm Er: glass fractional laser and fractional radiofrequency microneedle device for facial atrophic acne scar. J Cosm Dermatol. 2015;14:100–6.CrossRef Chae WS, Seong JY, Jung HN, Kong SH, Kim MH, Suh HS, et al. Comparative study on efficacy and safety of 1550 nm Er: glass fractional laser and fractional radiofrequency microneedle device for facial atrophic acne scar. J Cosm Dermatol. 2015;14:100–6.CrossRef
97.
Zurück zum Zitat Rongsaard N, Rummaneethorn P. Comparison of a fractional bipolar radiofrequency device and a fractional erbium-doped glass 1,550-nm device for the treatment of atrophic acne scars: a randomized split-face clinical study. Dermatol Surg. 2014;40:14–21.PubMedCrossRef Rongsaard N, Rummaneethorn P. Comparison of a fractional bipolar radiofrequency device and a fractional erbium-doped glass 1,550-nm device for the treatment of atrophic acne scars: a randomized split-face clinical study. Dermatol Surg. 2014;40:14–21.PubMedCrossRef
98.
Zurück zum Zitat Mahmoud BH, Srivastava D, Janiga JJ, Yang JJ, Lim HW, Ozog DM. Safety and efficacy of erbium-doped yttrium aluminum garnet fractionated laser for treatment of acne scars in type IV to VI skin. Dermatol Surg. 2010;36:602–9.PubMedCrossRef Mahmoud BH, Srivastava D, Janiga JJ, Yang JJ, Lim HW, Ozog DM. Safety and efficacy of erbium-doped yttrium aluminum garnet fractionated laser for treatment of acne scars in type IV to VI skin. Dermatol Surg. 2010;36:602–9.PubMedCrossRef
99.
Zurück zum Zitat Bencini PL, Tourlaki A, Galimberti M. Nonablative fractional photothermolysis for acne scars: clinical and in vivo microscopic documentation of treatment efficacy. Dermatol Ther. 2012;25:463–7.PubMedCrossRef Bencini PL, Tourlaki A, Galimberti M. Nonablative fractional photothermolysis for acne scars: clinical and in vivo microscopic documentation of treatment efficacy. Dermatol Ther. 2012;25:463–7.PubMedCrossRef
100.
Zurück zum Zitat Yoo KH, Ahn JY, Kim JY. The use of 1540 nm fractional photothermolysis for the treatment of acne scars in Asian skin: a pilot study. Photodermatol Photoimmunol Photomed. 2009;25:138–42.PubMedCrossRef Yoo KH, Ahn JY, Kim JY. The use of 1540 nm fractional photothermolysis for the treatment of acne scars in Asian skin: a pilot study. Photodermatol Photoimmunol Photomed. 2009;25:138–42.PubMedCrossRef
101.
Zurück zum Zitat Lipper GM, Perez M. Nonablative acne scar reduction after a series of treatments with a short-pulsed 1,064-nm neodymium:YAG laser. Dermatol Surg. 2006;32:998–1006.PubMed Lipper GM, Perez M. Nonablative acne scar reduction after a series of treatments with a short-pulsed 1,064-nm neodymium:YAG laser. Dermatol Surg. 2006;32:998–1006.PubMed
102.
Zurück zum Zitat Friedman PM, Jih MH, Skover GR. Treatment of atrophic facial acne scars with the 1064-nm Q-switched Nd:YAG laser: six-month follow-up study. Arch Dermatol. 2004;140:1337–41.PubMedCrossRef Friedman PM, Jih MH, Skover GR. Treatment of atrophic facial acne scars with the 1064-nm Q-switched Nd:YAG laser: six-month follow-up study. Arch Dermatol. 2004;140:1337–41.PubMedCrossRef
103.
Zurück zum Zitat Min SU, Choi YS, Lee DH, Yoon MY, Suh DH. Comparison of a long-pulse Nd:YAG laser and a combined 585/1,064-nm laser for the treatment of acne scars: a randomized split-face clinical study. Dermatol Surg. 2009;35:1720–7.PubMedCrossRef Min SU, Choi YS, Lee DH, Yoon MY, Suh DH. Comparison of a long-pulse Nd:YAG laser and a combined 585/1,064-nm laser for the treatment of acne scars: a randomized split-face clinical study. Dermatol Surg. 2009;35:1720–7.PubMedCrossRef
104.
Zurück zum Zitat Chan HL, Lam LK, Wong DS, Kono T, Trendell SN. Use of 1320 nm Nd:YAG laser for wrinkle reduction and the treatment of atrophic acne scarring in Asians. Lasers Surg Med. 2004;34:98–103.PubMedCrossRef Chan HL, Lam LK, Wong DS, Kono T, Trendell SN. Use of 1320 nm Nd:YAG laser for wrinkle reduction and the treatment of atrophic acne scarring in Asians. Lasers Surg Med. 2004;34:98–103.PubMedCrossRef
105.
Zurück zum Zitat Tanzi EL, Alster TS. Comparison of a 1450-nm diode laser and a 1320-nm Nd:YAG laser in the treatment of atrophic facial scars: a prospective clinical and histologic study. Dermatol Surg. 2004;30:152–7.PubMed Tanzi EL, Alster TS. Comparison of a 1450-nm diode laser and a 1320-nm Nd:YAG laser in the treatment of atrophic facial scars: a prospective clinical and histologic study. Dermatol Surg. 2004;30:152–7.PubMed
106.
Zurück zum Zitat Chua SH, Ang P, Khoo LS, Goh CL. Nonablative 1450 nm diode laser in the treatment of facial atrophic acne scars in type IV to V Asian skin: a prospective study. Dermatol Surg. 2004;30:1287–91.PubMed Chua SH, Ang P, Khoo LS, Goh CL. Nonablative 1450 nm diode laser in the treatment of facial atrophic acne scars in type IV to V Asian skin: a prospective study. Dermatol Surg. 2004;30:1287–91.PubMed
107.
Zurück zum Zitat Badawi A, Tome MA, Atteya A, Sami N, Morsy IA. Retrospective analysis of non-ablative scar treatment in dark skin types using the sub-millisecond Nd:YAG 1064 nm laser. Lasers Surg Med. 2011;43:130–6.PubMedCrossRef Badawi A, Tome MA, Atteya A, Sami N, Morsy IA. Retrospective analysis of non-ablative scar treatment in dark skin types using the sub-millisecond Nd:YAG 1064 nm laser. Lasers Surg Med. 2011;43:130–6.PubMedCrossRef
108.
Zurück zum Zitat Politi Y, Levi A, Lapidoth M. Integrated cooling-vacuum-assisted non-fractional 1540 nm Erbium: glass laser is effective in treating acne scars. J Drugs Dermatol. 2016;15:1359–63.PubMed Politi Y, Levi A, Lapidoth M. Integrated cooling-vacuum-assisted non-fractional 1540 nm Erbium: glass laser is effective in treating acne scars. J Drugs Dermatol. 2016;15:1359–63.PubMed
109.
Zurück zum Zitat Brauer JA, Kazlouskaya V, Alabdulrazzaq H, Bae Y, Bernstein LJ, Anolk R, et al. Use of a picosecond pulse duration laser with specialized optic for treatment of facial acne scarring. JAMA Dermatol. 2015;151:278–84.PubMedCrossRef Brauer JA, Kazlouskaya V, Alabdulrazzaq H, Bae Y, Bernstein LJ, Anolk R, et al. Use of a picosecond pulse duration laser with specialized optic for treatment of facial acne scarring. JAMA Dermatol. 2015;151:278–84.PubMedCrossRef
110.
Zurück zum Zitat Kim JE, Lee HW, Kim JK, Moon SH, Ko JW, Lee MW, et al. Objective evaluation of the clinical efficacy of fractional radiofrequency treatment for acne scars and enlarged pores in Asian skin. Dermatol Surg. 2014;40:988–95.PubMedCrossRef Kim JE, Lee HW, Kim JK, Moon SH, Ko JW, Lee MW, et al. Objective evaluation of the clinical efficacy of fractional radiofrequency treatment for acne scars and enlarged pores in Asian skin. Dermatol Surg. 2014;40:988–95.PubMedCrossRef
111.
Zurück zum Zitat Zhang Z, Fei Y, Chen X, Lu W, Chen J. Comparison of a fractional microplasma radio frequency technology and carbon dioxide fractional laser for the treatment of atrophic acne scars: a randomized split-face clinical study. Dermatol Surg. 2013;39:559–66.PubMedCrossRef Zhang Z, Fei Y, Chen X, Lu W, Chen J. Comparison of a fractional microplasma radio frequency technology and carbon dioxide fractional laser for the treatment of atrophic acne scars: a randomized split-face clinical study. Dermatol Surg. 2013;39:559–66.PubMedCrossRef
112.
Zurück zum Zitat Kroepfl L, Emer JJ. Combination therapy for acne scarring: personal experience and clinical suggestions. J Drugs Dermatol. 2016;15:1413–9.PubMed Kroepfl L, Emer JJ. Combination therapy for acne scarring: personal experience and clinical suggestions. J Drugs Dermatol. 2016;15:1413–9.PubMed
113.
Zurück zum Zitat Cameli N, Mariano M, Serio M, Ardigo M. Preliminary comparison of fractional laser with fractional laser plus radiofrequency for the treatment of acne scars and photoaging. Dermatol Surg. 2014;40:553–61.PubMedCrossRef Cameli N, Mariano M, Serio M, Ardigo M. Preliminary comparison of fractional laser with fractional laser plus radiofrequency for the treatment of acne scars and photoaging. Dermatol Surg. 2014;40:553–61.PubMedCrossRef
114.
Zurück zum Zitat Tenna S, Cogliandro A, Piombino L, Filoni A, Persichetti P. Combined use of fractional CO2 laser and radiofrequency waves to treat acne scars: a pilot study on 15 patients. J Cosmet Laser Ther. 2012;14:166–71.PubMedCrossRef Tenna S, Cogliandro A, Piombino L, Filoni A, Persichetti P. Combined use of fractional CO2 laser and radiofrequency waves to treat acne scars: a pilot study on 15 patients. J Cosmet Laser Ther. 2012;14:166–71.PubMedCrossRef
115.
Zurück zum Zitat Simmons BJ, Griffith RD, Falto-Aizpurua LA, Nouri K. Use of radiofrequency in cosmetic dermatology: focus on nonablative treatment of acne scars. Clin Cosmet Investig Dermatol. 2014;7:335–9.PubMedPubMedCentralCrossRef Simmons BJ, Griffith RD, Falto-Aizpurua LA, Nouri K. Use of radiofrequency in cosmetic dermatology: focus on nonablative treatment of acne scars. Clin Cosmet Investig Dermatol. 2014;7:335–9.PubMedPubMedCentralCrossRef
116.
Zurück zum Zitat Chandrashekar BS, Sriram R, Mysore R, Bhaskar S, Shetty A. Evaluation of microneedling fractional radiofrequency device for treatment of acne scars. J Cutan Aesthet Surg. 2014;7:93–7.PubMedPubMedCentralCrossRef Chandrashekar BS, Sriram R, Mysore R, Bhaskar S, Shetty A. Evaluation of microneedling fractional radiofrequency device for treatment of acne scars. J Cutan Aesthet Surg. 2014;7:93–7.PubMedPubMedCentralCrossRef
117.
Zurück zum Zitat Kaminaka C, Uede M, Matsunaka H, Furukawa F. Clinical studies of the treatment of facial atrophic acne scars and acne with a bipolar fractional radiofrequency system. J Dermatol. 2015;42:580–7.PubMedCrossRef Kaminaka C, Uede M, Matsunaka H, Furukawa F. Clinical studies of the treatment of facial atrophic acne scars and acne with a bipolar fractional radiofrequency system. J Dermatol. 2015;42:580–7.PubMedCrossRef
118.
Zurück zum Zitat Min S, Park SY, Yoon JY, Suh DH. Comparison of fractional microneedling radiofrequency and bipolar radiofrequency on acne and acne scar and investigation of mechanism: comparative randomized controlled clinical trial. Arch Dermatol Res. 2015;307:897–904.PubMedCrossRef Min S, Park SY, Yoon JY, Suh DH. Comparison of fractional microneedling radiofrequency and bipolar radiofrequency on acne and acne scar and investigation of mechanism: comparative randomized controlled clinical trial. Arch Dermatol Res. 2015;307:897–904.PubMedCrossRef
119.
Zurück zum Zitat Min S, Park SY, Yoon JY, Kwon HH, Suh DH. Fractional microneedling radiofrequency treatment for acne-related post-inflammatory erythema. Acta Derm Venereol. 2016;96:87–91.PubMedCrossRef Min S, Park SY, Yoon JY, Kwon HH, Suh DH. Fractional microneedling radiofrequency treatment for acne-related post-inflammatory erythema. Acta Derm Venereol. 2016;96:87–91.PubMedCrossRef
120.
Zurück zum Zitat Cho SI, Chung BY, Choi MG, Baek JH, Cho HJ, Park CW, et al. Evaluation of the clinical efficacy of fractional radiofrequency microneedle treatment in acne scars and large facial pores. Dermatol Surg. 2012;38:1017–24.PubMedCrossRef Cho SI, Chung BY, Choi MG, Baek JH, Cho HJ, Park CW, et al. Evaluation of the clinical efficacy of fractional radiofrequency microneedle treatment in acne scars and large facial pores. Dermatol Surg. 2012;38:1017–24.PubMedCrossRef
121.
Zurück zum Zitat Vejjabhinanta V, Wanitphakdeedecha R, Limtanyakul P, Manuskiatti W. The efficacy in treatment of facial atrophic acne scars in Asians with a fractional radiofrequency microneedle system. J Eur Acad Dermatol Venereol. 2014;28:1219–25.PubMedCrossRef Vejjabhinanta V, Wanitphakdeedecha R, Limtanyakul P, Manuskiatti W. The efficacy in treatment of facial atrophic acne scars in Asians with a fractional radiofrequency microneedle system. J Eur Acad Dermatol Venereol. 2014;28:1219–25.PubMedCrossRef
122.
Zurück zum Zitat Park JY, Lee EG, Yoon MS, Lee HJ. The efficacy and safety of combined microneedle fractional radiofrequency and sublative fractional radiofrequency for acne scars in Asian skin. J Cosmet Dermatol. 2016;15:102–7.PubMedCrossRef Park JY, Lee EG, Yoon MS, Lee HJ. The efficacy and safety of combined microneedle fractional radiofrequency and sublative fractional radiofrequency for acne scars in Asian skin. J Cosmet Dermatol. 2016;15:102–7.PubMedCrossRef
123.
Zurück zum Zitat Goel A, Gatne V. Use of nanofractional radiofrequency for the treatment of acne scars in Indian skin. J Cosmet Dermatol. 2017;16:186–92.PubMedCrossRef Goel A, Gatne V. Use of nanofractional radiofrequency for the treatment of acne scars in Indian skin. J Cosmet Dermatol. 2017;16:186–92.PubMedCrossRef
124.
Zurück zum Zitat Faghihi G, Nouraei S, Asilian A, Keyvan S, Abtahi-Naeini B, Rakhshanpour M, et al. Efficacy of punch elevation combined with fractional carbon dioxide laser resurfacing in facial atrophic acne scarring: a randomized split-face clinical study. Indian J Dermatol. 2015;60:473–8.PubMedPubMedCentralCrossRef Faghihi G, Nouraei S, Asilian A, Keyvan S, Abtahi-Naeini B, Rakhshanpour M, et al. Efficacy of punch elevation combined with fractional carbon dioxide laser resurfacing in facial atrophic acne scarring: a randomized split-face clinical study. Indian J Dermatol. 2015;60:473–8.PubMedPubMedCentralCrossRef
125.
Zurück zum Zitat Solotoff S. Treatment of pitted acne scarring-postauricular punch grafts followed by dermabrasion. J Dermatol Surg Oncol. 1986;12:1079.PubMedCrossRef Solotoff S. Treatment of pitted acne scarring-postauricular punch grafts followed by dermabrasion. J Dermatol Surg Oncol. 1986;12:1079.PubMedCrossRef
126.
Zurück zum Zitat O’Daniel TG. Multimodal management of atrophic acne scarring in the aging face. Aesth Plast Surg. 2011;35:1143–50.CrossRef O’Daniel TG. Multimodal management of atrophic acne scarring in the aging face. Aesth Plast Surg. 2011;35:1143–50.CrossRef
127.
Zurück zum Zitat Ibrahim ZA, Eltatawy RA, Ghaly NR, Abd El-Naby NM, Abou El Fetouh HM, Abd Elateef AE, et al. Autologus bone marrow stem cells in atrophic acne scars: a pilot study. J Dermatol Treat. 2015;26:260–5.CrossRef Ibrahim ZA, Eltatawy RA, Ghaly NR, Abd El-Naby NM, Abou El Fetouh HM, Abd Elateef AE, et al. Autologus bone marrow stem cells in atrophic acne scars: a pilot study. J Dermatol Treat. 2015;26:260–5.CrossRef
128.
Zurück zum Zitat Munavalli GS, Smith S, Maslowski JM, Weiss RA. Successful treatment of depressed, distensible acne scars using autologous fibroblasts: a multi-site, prospective, double blind, placebo-controlled clinical trial. Dermatol Surg. 2013;39:1226–36.PubMedPubMedCentralCrossRef Munavalli GS, Smith S, Maslowski JM, Weiss RA. Successful treatment of depressed, distensible acne scars using autologous fibroblasts: a multi-site, prospective, double blind, placebo-controlled clinical trial. Dermatol Surg. 2013;39:1226–36.PubMedPubMedCentralCrossRef
129.
Zurück zum Zitat Stoddard MA, Herrmann J, Moy L, Moy R. Improvement of atrophic acne scars in skin of color using topical synthetic epidermal growth factor (EGF) serum: a pilot study. J Drugs Dermatol. 2017;16:322–6.PubMed Stoddard MA, Herrmann J, Moy L, Moy R. Improvement of atrophic acne scars in skin of color using topical synthetic epidermal growth factor (EGF) serum: a pilot study. J Drugs Dermatol. 2017;16:322–6.PubMed
130.
Zurück zum Zitat Zaleski-Larsen LA, Fabi SG, McGraw T, Taylor M. Acne scar treatment: a multimodality approach tailored to scar type. Dermatol Surg. 2016;42:139–49.CrossRef Zaleski-Larsen LA, Fabi SG, McGraw T, Taylor M. Acne scar treatment: a multimodality approach tailored to scar type. Dermatol Surg. 2016;42:139–49.CrossRef
131.
Zurück zum Zitat Taub AF, Garretson CB. Treatment of acne scars of skin types ii to v by sublative fractional bipolar radiofrequency and bipolar radiofrequency combined with diode laser. J Clin Aesthet Dermatol. 2011;4:18–27.PubMedPubMedCentral Taub AF, Garretson CB. Treatment of acne scars of skin types ii to v by sublative fractional bipolar radiofrequency and bipolar radiofrequency combined with diode laser. J Clin Aesthet Dermatol. 2011;4:18–27.PubMedPubMedCentral
132.
Zurück zum Zitat Yeung CK, Chan NP, Shek SY, Chan HH. Evaluation of combined fractional radiofrequency and fractional laser treatment for acne scars in Asians. Lasers Surg Med. 2012;44:622–30.PubMedCrossRef Yeung CK, Chan NP, Shek SY, Chan HH. Evaluation of combined fractional radiofrequency and fractional laser treatment for acne scars in Asians. Lasers Surg Med. 2012;44:622–30.PubMedCrossRef
133.
Zurück zum Zitat Peterson JD, Palm MD, Kiripolsky MG, Guiha IC, Goldman MP. Evaluation of the effect of fractional laser with radiofrequency and fractionated radiofrequency on the improvement of acne scars. Dermatol Surg. 2011;37:1260–7.PubMedCrossRef Peterson JD, Palm MD, Kiripolsky MG, Guiha IC, Goldman MP. Evaluation of the effect of fractional laser with radiofrequency and fractionated radiofrequency on the improvement of acne scars. Dermatol Surg. 2011;37:1260–7.PubMedCrossRef
134.
Zurück zum Zitat Taylor MB, Zaleski-Larsen L, McGraw TA. Single session treatment of rolling acne scars using tumescent anesthesia, 20% trichloroacetic acid, extensive subcision, and fractional CO2 laser. Dermatol Surg. 2017;43:S70–4.PubMedCrossRef Taylor MB, Zaleski-Larsen L, McGraw TA. Single session treatment of rolling acne scars using tumescent anesthesia, 20% trichloroacetic acid, extensive subcision, and fractional CO2 laser. Dermatol Surg. 2017;43:S70–4.PubMedCrossRef
135.
Zurück zum Zitat Anupama YG, Wahab AJ. Effectiveness of CO2 laser with subcision in patients with acne scars. J Cosmet Laser Ther. 2016;18:367–71.PubMedCrossRef Anupama YG, Wahab AJ. Effectiveness of CO2 laser with subcision in patients with acne scars. J Cosmet Laser Ther. 2016;18:367–71.PubMedCrossRef
136.
Zurück zum Zitat Nilforoushzadeh MA, Faghihi G, Jaffary F, Haftbaradaran E, Hoseini SM, Mazaheri N. Fractional carbon dioxide laser and its combination with subcision in improving atrophic acne scars. Adv Biomed Res. 2017;6:20.PubMedPubMedCentralCrossRef Nilforoushzadeh MA, Faghihi G, Jaffary F, Haftbaradaran E, Hoseini SM, Mazaheri N. Fractional carbon dioxide laser and its combination with subcision in improving atrophic acne scars. Adv Biomed Res. 2017;6:20.PubMedPubMedCentralCrossRef
138.
Zurück zum Zitat Faghihi G, Poostiyan N, Asilian A, Abtahi-Naeini B, Shahbazi M, Iraji F, et al. Efficacy of fractionated microneedle radiofrequency with and without adding subcision for the treatment of atrophic facial acne scars: a randomized split-face clinical study. J Cosmet Dermatol. 2017;16:223–9.PubMedCrossRef Faghihi G, Poostiyan N, Asilian A, Abtahi-Naeini B, Shahbazi M, Iraji F, et al. Efficacy of fractionated microneedle radiofrequency with and without adding subcision for the treatment of atrophic facial acne scars: a randomized split-face clinical study. J Cosmet Dermatol. 2017;16:223–9.PubMedCrossRef
139.
Zurück zum Zitat Sobanko JF, Alster TS. Management of acne scarring, part I: a comparative review of laser surgical approaches. Am J Clin Dermatol. 2012;13:319–30.PubMedCrossRef Sobanko JF, Alster TS. Management of acne scarring, part I: a comparative review of laser surgical approaches. Am J Clin Dermatol. 2012;13:319–30.PubMedCrossRef
140.
Zurück zum Zitat Fitzpatrick RE. Treatment of inflamed hypertrophic scars using intralesional 5-FU. Dermatol Surg. 1999;25:224–32.PubMedCrossRef Fitzpatrick RE. Treatment of inflamed hypertrophic scars using intralesional 5-FU. Dermatol Surg. 1999;25:224–32.PubMedCrossRef
141.
Zurück zum Zitat Alster TS, Handrick C. Laser treatment of hypertrophic scars, keloids, and striae. Semin Cutan Med Surg. 2000;19:287–92.PubMedCrossRef Alster TS, Handrick C. Laser treatment of hypertrophic scars, keloids, and striae. Semin Cutan Med Surg. 2000;19:287–92.PubMedCrossRef
142.
Zurück zum Zitat Shih PY, Chen HH, Chen CH, Hong HS. Rapid recurrence of keloid after pulse dye laser treatment. Dermatol Surg. 2008;34:1124–7.PubMed Shih PY, Chen HH, Chen CH, Hong HS. Rapid recurrence of keloid after pulse dye laser treatment. Dermatol Surg. 2008;34:1124–7.PubMed
144.
Zurück zum Zitat Kearney C, Brew D. Single-session combination treatment with intense pulsed light and nonablative fractional photothermolysis: a split-face study. Dermatol Surg. 2012;38:1002–9.PubMedCrossRef Kearney C, Brew D. Single-session combination treatment with intense pulsed light and nonablative fractional photothermolysis: a split-face study. Dermatol Surg. 2012;38:1002–9.PubMedCrossRef
145.
Zurück zum Zitat Alster TS, Mcmeekin TO. Improvement of facial acne scars by the 585 nm flashlamp-pumped pulsed dye laser. J Am Acad Dermatol. 1996;35:79–81.PubMedCrossRef Alster TS, Mcmeekin TO. Improvement of facial acne scars by the 585 nm flashlamp-pumped pulsed dye laser. J Am Acad Dermatol. 1996;35:79–81.PubMedCrossRef
146.
Zurück zum Zitat Park KY, Ko EJ, Seo SJ, Hong CK. Comparison of fractional, nonablative, 1550-nm laser and 595-nm pulsed dye laser for the treatment of facial erythema resulting from acne: a split-face, evaluator-blinded, randomized pilot study. J Cosmet Laser Ther. 2014;16:120–3.PubMedCrossRef Park KY, Ko EJ, Seo SJ, Hong CK. Comparison of fractional, nonablative, 1550-nm laser and 595-nm pulsed dye laser for the treatment of facial erythema resulting from acne: a split-face, evaluator-blinded, randomized pilot study. J Cosmet Laser Ther. 2014;16:120–3.PubMedCrossRef
147.
148.
Zurück zum Zitat Alexis AF, Coley MK, Nijhawan RI, Luke JD, Shah SK, Argobi YA, et al. Nonablative fractional laser resurfacing for acne scarring in patients with Fitzpatrick skin phototypes IV–VI. Dermatol Surg. 2016;42:392–402.PubMedCrossRef Alexis AF, Coley MK, Nijhawan RI, Luke JD, Shah SK, Argobi YA, et al. Nonablative fractional laser resurfacing for acne scarring in patients with Fitzpatrick skin phototypes IV–VI. Dermatol Surg. 2016;42:392–402.PubMedCrossRef
149.
Zurück zum Zitat Cohen BE, Elbuluk N. Microneedling in skin of color: a review of uses and efficacy. J Am Acad Dermatol. 2016;74:348–55.PubMedCrossRef Cohen BE, Elbuluk N. Microneedling in skin of color: a review of uses and efficacy. J Am Acad Dermatol. 2016;74:348–55.PubMedCrossRef
150.
Zurück zum Zitat Saluja SS, Walker ML, Summers EM, Tristani-Firouzi P, Smart DR. Safety of non-ablative fractional laser for acne scars within 1 month after treatment with oral isotretinoin: a randomized split-face controlled trial. Lasers Surg Med. 2017;49:886–90.PubMedCrossRef Saluja SS, Walker ML, Summers EM, Tristani-Firouzi P, Smart DR. Safety of non-ablative fractional laser for acne scars within 1 month after treatment with oral isotretinoin: a randomized split-face controlled trial. Lasers Surg Med. 2017;49:886–90.PubMedCrossRef
151.
Zurück zum Zitat Spring LK, Krakowski AC, Alam M, Bhatia A, Brauer J, Cohen J, et al. Isotretinoin and timing of procedural interventions: a systematic review with consensus recommendations. JAMA Dermatol. 2017;153:802–9.PubMedCrossRef Spring LK, Krakowski AC, Alam M, Bhatia A, Brauer J, Cohen J, et al. Isotretinoin and timing of procedural interventions: a systematic review with consensus recommendations. JAMA Dermatol. 2017;153:802–9.PubMedCrossRef
Metadaten
Titel
Acne Scarring Management: Systematic Review and Evaluation of the Evidence
verfasst von
Shashank Bhargava
Paulo R. Cunha
Jennifer Lee
George Kroumpouzos
Publikationsdatum
01.08.2018
Verlag
Springer International Publishing
Erschienen in
American Journal of Clinical Dermatology / Ausgabe 4/2018
Print ISSN: 1175-0561
Elektronische ISSN: 1179-1888
DOI
https://doi.org/10.1007/s40257-018-0358-5

Weitere Artikel der Ausgabe 4/2018

American Journal of Clinical Dermatology 4/2018 Zur Ausgabe

Leitlinien kompakt für die Dermatologie

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Hirsutismus bei PCOS: Laser- und Lichttherapien helfen

26.04.2024 Hirsutismus Nachrichten

Laser- und Lichtbehandlungen können bei Frauen mit polyzystischem Ovarialsyndrom (PCOS) den übermäßigen Haarwuchs verringern und das Wohlbefinden verbessern – bei alleiniger Anwendung oder in Kombination mit Medikamenten.

Bei schweren Reaktionen auf Insektenstiche empfiehlt sich eine spezifische Immuntherapie

Insektenstiche sind bei Erwachsenen die häufigsten Auslöser einer Anaphylaxie. Einen wirksamen Schutz vor schweren anaphylaktischen Reaktionen bietet die allergenspezifische Immuntherapie. Jedoch kommt sie noch viel zu selten zum Einsatz.

Auf diese Krankheiten bei Geflüchteten sollten Sie vorbereitet sein

22.04.2024 DGIM 2024 Nachrichten

Um Menschen nach der Flucht aus einem Krisengebiet bestmöglich medizinisch betreuen zu können, ist es gut zu wissen, welche Erkrankungen im jeweiligen Herkunftsland häufig sind. Dabei hilft eine Internetseite der CDC (Centers for Disease Control and Prevention).

Kein Abstrich bei chronischen Wunden ohne Entzündungszeichen!

16.04.2024 DGIM 2024 Nachrichten

Den Reflex, eine oberflächliche chronische Hautwunde ohne Entzündungszeichen in jedem Fall abzustreichen, sollte man nach einer neuen „Klug-entscheiden“-Empfehlung unterdrücken.

Update Dermatologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.