Background
Methods
Study population
Measurement of TcB and TSB
Follow-up of studied infants
Outcome
Statistical analysis
Results
Variables | Neonates (298) |
---|---|
Gestational age (wks)
| 38.7 ± 1.4 |
> 37 |
279 (93.6)
|
35 - 36
|
19 (6.4)
|
Birth weight (g)
|
3200 ± 440
|
Male
|
143 (48.0)
|
Mode of delivery
| |
Vaginal
|
174 (58.4)
|
Cesarean section
|
117 (39.3)
|
Ventouse
|
7 (2.3)
|
Feeding
| |
Exclusive breast feeding
|
104 (34.9)
|
Breast + bottle feeding
|
160 (53.7)
|
Bottle feeding
|
34 (11.4)
|
Delayed meconium passage (>24 hrs)
|
20 (6.7)
|
Weight loss >10 %
|
12 (4.0)
|
Significant hyperbilirubinemia
|
16 (5.4)
|
Required phototherapy
|
9 (3.0)
|
TSB >17 mg/dL
|
7 (2.3)
|
Hours of age | TP (n) | FN (n) | TN (n) | FP (n) | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) |
---|---|---|---|---|---|---|---|---|
JM-103 | ||||||||
24 to 48 hours
| 2 | 2 | 124 | 47 | 50.0 | 72.5 | 4.1 | 98.4 |
49 to 60 hours
| 4 | 1 | 79 | 21 | 80.0 | 79.0 | 16.0 | 98.8 |
61 to 72 hours
| 5 | 0 | 129 | 37 | 100 | 77.7 | 11.9 | 100 |
73 to 96 hours
| 13 | 0 | 117 | 46 | 100 | 71.8 | 22.0 | 100 |
Total
| 24 | 3 | 449 | 151 | 88.9 | 74.8 | 13.7 | 99.3 |
Bilicheck
| ||||||||
24 to 48 hours
| 3 | 1 | 73 | 98 | 75.0 | 42.7 | 3.0 | 98.6 |
49 to 60 hours
| 4 | 1 | 45 | 55 | 80.0 | 45.0 | 6.8 | 97.8 |
61 to 72 hours
| 5 | 0 | 82 | 84 | 100 | 49.4 | 5.6 | 100 |
73 to 96 hours
| 13 | 0 | 73 | 90 | 100 | 44.8 | 12.6 | 100 |
Total
| 25 | 2 | 273 | 327 | 92.6 | 45.5 | 7.1 | 99.3 |