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Erschienen in: Critical Care 2/2013

01.04.2013 | Viewpoint

The potential harm of oxygen therapy in medical emergencies

verfasst von: Alexander D Cornet, Albertus J Kooter, Mike JL Peters, Yvo M Smulders

Erschienen in: Critical Care | Ausgabe 2/2013

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Abstract

In medical emergencies, supplemental oxygen is often administrated routinely. Most paramedics and physicians believe that high concentrations of oxygen are life-saving [1]. Over the last century, however, a plethora of studies point to possible detrimental effects of hyperoxia induced by supplemental oxygen in a variety of medical emergencies. This viewpoint provides a historical overview and questions the safety of routine high-dose oxygen administration and is based on pathophysiology and (pre)clinical findings in various medical emergencies.
Literatur
1.
Zurück zum Zitat Burls A, Emparanza JI, Quinn T, Cabello JB: Oxygen use in acute myocardial infarction: an online survey of health professionals' practice and beliefs. Emerg Med J 2010, 27: 283-286. 10.1136/emj.2009.077370CrossRefPubMed Burls A, Emparanza JI, Quinn T, Cabello JB: Oxygen use in acute myocardial infarction: an online survey of health professionals' practice and beliefs. Emerg Med J 2010, 27: 283-286. 10.1136/emj.2009.077370CrossRefPubMed
2.
Zurück zum Zitat Steele C: Severe angina pectoris relieved by oxygen inhalations. BMJ 1900, 2: 1568. Steele C: Severe angina pectoris relieved by oxygen inhalations. BMJ 1900, 2: 1568.
3.
Zurück zum Zitat Keefer CS, Resnik WH: Angina pectoris: a syndrome caused by anoxemia of the myocardium. Arch Intern Med 1928, 41: 769-807. 10.1001/archinte.1928.00130180002001CrossRef Keefer CS, Resnik WH: Angina pectoris: a syndrome caused by anoxemia of the myocardium. Arch Intern Med 1928, 41: 769-807. 10.1001/archinte.1928.00130180002001CrossRef
4.
Zurück zum Zitat Boland EW: Oxygen in high concentrations for relief of pain in coronary thrombosis and severe angina pectoris. JAMA 1940, 114: 1512-1514. Boland EW: Oxygen in high concentrations for relief of pain in coronary thrombosis and severe angina pectoris. JAMA 1940, 114: 1512-1514.
5.
Zurück zum Zitat Horvat M, Yoshida S, Prakash R, Marcus HS, Swan HJC, Ganz W: Effects of oxygen breathing on pacing-induced angina pectoris and other manifestations of coronary insufficiency. Circulation 1972, 45: 837-844. 10.1161/01.CIR.45.4.837CrossRefPubMed Horvat M, Yoshida S, Prakash R, Marcus HS, Swan HJC, Ganz W: Effects of oxygen breathing on pacing-induced angina pectoris and other manifestations of coronary insufficiency. Circulation 1972, 45: 837-844. 10.1161/01.CIR.45.4.837CrossRefPubMed
6.
Zurück zum Zitat Madias JE, Madias NE, Hood WB: Precordial ST-segment mapping: 2. Effects of oxygen inhalation on ischemic injury in patients with acute myocardial infarction. Circulation 1976, 53: 411-417. 10.1161/01.CIR.53.3.411CrossRefPubMed Madias JE, Madias NE, Hood WB: Precordial ST-segment mapping: 2. Effects of oxygen inhalation on ischemic injury in patients with acute myocardial infarction. Circulation 1976, 53: 411-417. 10.1161/01.CIR.53.3.411CrossRefPubMed
7.
Zurück zum Zitat Russek HI, Regan FD, Naegele CF: One hundred percent oxygen in the treatment of acute myocardial infarction and severe angina pectoris. J Am Med Assoc 1950, 144: 373-375. 10.1001/jama.1950.02920050013003CrossRefPubMed Russek HI, Regan FD, Naegele CF: One hundred percent oxygen in the treatment of acute myocardial infarction and severe angina pectoris. J Am Med Assoc 1950, 144: 373-375. 10.1001/jama.1950.02920050013003CrossRefPubMed
8.
Zurück zum Zitat MacKenzie GJ, Flenley DC, Taylor SH, McDonald AH, Staunton HP, Donald KW: Circulatory and respiratory studies in myocardial infarction and cardiogenic shock. Lancet 1964, 2: 825-832.CrossRefPubMed MacKenzie GJ, Flenley DC, Taylor SH, McDonald AH, Staunton HP, Donald KW: Circulatory and respiratory studies in myocardial infarction and cardiogenic shock. Lancet 1964, 2: 825-832.CrossRefPubMed
9.
Zurück zum Zitat Thomas M, Malmcroma R, Shillingford J: Haemodynamic effects of oxygen in patients with acute myocardial infarction. Brit Heart J 1965, 27: 401-407. 10.1136/hrt.27.3.401PubMedCentralCrossRefPubMed Thomas M, Malmcroma R, Shillingford J: Haemodynamic effects of oxygen in patients with acute myocardial infarction. Brit Heart J 1965, 27: 401-407. 10.1136/hrt.27.3.401PubMedCentralCrossRefPubMed
10.
Zurück zum Zitat Kenmure ACF, Murdoch WR, Beattie AD, Marshall JCB, Cameron AJV: Circulatory and metabolic effects of oxygen in myocardial infarction. Brit Med J 1968, 4: 360-364. 10.1136/bmj.4.5627.360PubMedCentralCrossRefPubMed Kenmure ACF, Murdoch WR, Beattie AD, Marshall JCB, Cameron AJV: Circulatory and metabolic effects of oxygen in myocardial infarction. Brit Med J 1968, 4: 360-364. 10.1136/bmj.4.5627.360PubMedCentralCrossRefPubMed
11.
Zurück zum Zitat Neill WA: Effects of arterial hypoxemia and hyperoxia on oxygen availability for myocardial metabolism: patients with and without coronary heart disease. Am J Cardiol 1969, 24: 166-171. 10.1016/0002-9149(69)90399-3CrossRefPubMed Neill WA: Effects of arterial hypoxemia and hyperoxia on oxygen availability for myocardial metabolism: patients with and without coronary heart disease. Am J Cardiol 1969, 24: 166-171. 10.1016/0002-9149(69)90399-3CrossRefPubMed
12.
Zurück zum Zitat Bourassa MG, Campeau L, Bois MA, Rico O: The effects of inhalation of 100 per cent oxygen on myocardial lactate metabolism in coronary heart disease. Am J Cardiol 1969, 24: 172-177. 10.1016/0002-9149(69)90400-7CrossRefPubMed Bourassa MG, Campeau L, Bois MA, Rico O: The effects of inhalation of 100 per cent oxygen on myocardial lactate metabolism in coronary heart disease. Am J Cardiol 1969, 24: 172-177. 10.1016/0002-9149(69)90400-7CrossRefPubMed
13.
Zurück zum Zitat Sukumalchantra Y, Levy S, Danzig R, Rubins S, Alpern H, Swan HJ: Correcting arterial hypoxemia by oxygen therapy in patients with acute myocardial infarction. Am J Cardiol 1969, 24: 838-852. 10.1016/0002-9149(69)90474-3CrossRefPubMed Sukumalchantra Y, Levy S, Danzig R, Rubins S, Alpern H, Swan HJ: Correcting arterial hypoxemia by oxygen therapy in patients with acute myocardial infarction. Am J Cardiol 1969, 24: 838-852. 10.1016/0002-9149(69)90474-3CrossRefPubMed
14.
Zurück zum Zitat Jamieson D, Chance B, Cadenas E, Boveris A: The relation of free radical production to hyperoxia. Annu Rev Physiol 1986, 48: 703-719. 10.1146/annurev.ph.48.030186.003415CrossRefPubMed Jamieson D, Chance B, Cadenas E, Boveris A: The relation of free radical production to hyperoxia. Annu Rev Physiol 1986, 48: 703-719. 10.1146/annurev.ph.48.030186.003415CrossRefPubMed
15.
Zurück zum Zitat McNulty PH, Robertson BJ, Tulli MA, Hess J, Harach LA, Scott S, Sinoway LI: Effect of hyperoxia and vitamin C on coronary blood flow in patients with ischaemic heart disease. J Appl Physiol 2007, 102: 2040-2045. 10.1152/japplphysiol.00595.2006CrossRefPubMed McNulty PH, Robertson BJ, Tulli MA, Hess J, Harach LA, Scott S, Sinoway LI: Effect of hyperoxia and vitamin C on coronary blood flow in patients with ischaemic heart disease. J Appl Physiol 2007, 102: 2040-2045. 10.1152/japplphysiol.00595.2006CrossRefPubMed
16.
Zurück zum Zitat McNulty PH, King N, Scott S, Hartman G, McCann J, Kozak M, Chambers CE, Demers LM, Sinoway LI: Effects of supplemental oxygen administration on coronary blood flow in patients undergoing cardiac catheterization. Am J Physiol Heart Circ Physiol 2005, 288: H1057-H1062.CrossRefPubMed McNulty PH, King N, Scott S, Hartman G, McCann J, Kozak M, Chambers CE, Demers LM, Sinoway LI: Effects of supplemental oxygen administration on coronary blood flow in patients undergoing cardiac catheterization. Am J Physiol Heart Circ Physiol 2005, 288: H1057-H1062.CrossRefPubMed
17.
Zurück zum Zitat Messina EJ, Sun D, Koller A, Wolin MS, Kaley F: Increases in oxygen tension evoke arteriolar constriction by inhibiting endothelial prostaglandin synthesis. Microvasc Res 1994, 48: 151-160. 10.1006/mvre.1994.1046CrossRefPubMed Messina EJ, Sun D, Koller A, Wolin MS, Kaley F: Increases in oxygen tension evoke arteriolar constriction by inhibiting endothelial prostaglandin synthesis. Microvasc Res 1994, 48: 151-160. 10.1006/mvre.1994.1046CrossRefPubMed
18.
Zurück zum Zitat Mouren S, Souktani R, Beaussier M, Abdenour L, Arthaud M, Duvelleroy M, Vicaut E: Mechanisms of coronary vasoconstriction induced by high arterial oxygen tension. Am J Physiol 1997, 272: H67-H75.PubMed Mouren S, Souktani R, Beaussier M, Abdenour L, Arthaud M, Duvelleroy M, Vicaut E: Mechanisms of coronary vasoconstriction induced by high arterial oxygen tension. Am J Physiol 1997, 272: H67-H75.PubMed
19.
Zurück zum Zitat Winegrad S, Henrion D, Rappaport L, Samuel JL: Self-protection by cardiac myocytes against hypoxia and hyperoxia. Circ Res 1999, 85: 690-698. 10.1161/01.RES.85.8.690CrossRefPubMed Winegrad S, Henrion D, Rappaport L, Samuel JL: Self-protection by cardiac myocytes against hypoxia and hyperoxia. Circ Res 1999, 85: 690-698. 10.1161/01.RES.85.8.690CrossRefPubMed
20.
Zurück zum Zitat Haque WA, Boehmer J, Clemson BS, Leuenberger UA, Silber DH, Sinoway LI: Hemodynamic effects of supplemental oxygen administration in congestive heart failure. J Am Coll Cardiol 1996, 27: 353-357.CrossRefPubMed Haque WA, Boehmer J, Clemson BS, Leuenberger UA, Silber DH, Sinoway LI: Hemodynamic effects of supplemental oxygen administration in congestive heart failure. J Am Coll Cardiol 1996, 27: 353-357.CrossRefPubMed
21.
Zurück zum Zitat Mak S, Egri Z, Tanna G, Colman R, Newton GE: Vitamin C prevents hyperoxia mediated vasoconstriction and impairment of endothelium-dependent vasodilation. Am J Physiol Heart Circ Physiol 2002, 282: H2414-2421.CrossRefPubMed Mak S, Egri Z, Tanna G, Colman R, Newton GE: Vitamin C prevents hyperoxia mediated vasoconstriction and impairment of endothelium-dependent vasodilation. Am J Physiol Heart Circ Physiol 2002, 282: H2414-2421.CrossRefPubMed
22.
Zurück zum Zitat Mak S, Azevedo ER, Liu PP, Newton GE: Effect of hyperoxia on left ventricular function and filling pressures in patients with and without congestive heart failure. Chest 2001, 120: 467-473. 10.1378/chest.120.2.467CrossRefPubMed Mak S, Azevedo ER, Liu PP, Newton GE: Effect of hyperoxia on left ventricular function and filling pressures in patients with and without congestive heart failure. Chest 2001, 120: 467-473. 10.1378/chest.120.2.467CrossRefPubMed
23.
Zurück zum Zitat Park JH, Balmain S, Berry C, Morton JJ, McMurray JJ: Potentially detrimental cardiovascular effects of oxygen in patients with chronic left ventricular systolic dysfunction. Heart 2010, 96: 533-538. 10.1136/hrt.2009.175257CrossRefPubMed Park JH, Balmain S, Berry C, Morton JJ, McMurray JJ: Potentially detrimental cardiovascular effects of oxygen in patients with chronic left ventricular systolic dysfunction. Heart 2010, 96: 533-538. 10.1136/hrt.2009.175257CrossRefPubMed
24.
Zurück zum Zitat Welsh DG, Jackson WF, Segal SS: Oxygen induces electromechanical coupling in arteriolar smooth muscle cells: a role for L-type Ca2+ channels. Am J Physiol 1998, 274: H2018-H2024.PubMed Welsh DG, Jackson WF, Segal SS: Oxygen induces electromechanical coupling in arteriolar smooth muscle cells: a role for L-type Ca2+ channels. Am J Physiol 1998, 274: H2018-H2024.PubMed
25.
Zurück zum Zitat Bak Z, Sjöberg F, Rousseau A, Steinvall I, Janerot-Sjoberg B: Human cardiovascular dose-response to supplemental oxygen. Acta Physiol (Oxf) 2007, 191: 15-24. 10.1111/j.1748-1716.2007.01710.xCrossRef Bak Z, Sjöberg F, Rousseau A, Steinvall I, Janerot-Sjoberg B: Human cardiovascular dose-response to supplemental oxygen. Acta Physiol (Oxf) 2007, 191: 15-24. 10.1111/j.1748-1716.2007.01710.xCrossRef
26.
27.
Zurück zum Zitat Ukholkina GB, Kostianov IIu, Kuchkina NV, Grendo EP, Gofman IaB: Effect of oxygen therapy used in combination with reperfusion in patients with acute myocardial infarction. Kardiologiia 2005, 45: 59.PubMed Ukholkina GB, Kostianov IIu, Kuchkina NV, Grendo EP, Gofman IaB: Effect of oxygen therapy used in combination with reperfusion in patients with acute myocardial infarction. Kardiologiia 2005, 45: 59.PubMed
28.
Zurück zum Zitat Cabello JB, Burls A, Emparanza JI, Bayliss S, Quinn T: Oxygen therapy for acute myocardial infarction. Cochrane Database Syst Rev 2010, 6: CD007160.PubMed Cabello JB, Burls A, Emparanza JI, Bayliss S, Quinn T: Oxygen therapy for acute myocardial infarction. Cochrane Database Syst Rev 2010, 6: CD007160.PubMed
29.
Zurück zum Zitat Sassoon CS, Hassell KT, Mahutte CK: Hyperoxic-induced hypercapnia in stable chronic obstructive pulmonary disease. Am Rev Respir Dis 1987, 135: 907-911.CrossRefPubMed Sassoon CS, Hassell KT, Mahutte CK: Hyperoxic-induced hypercapnia in stable chronic obstructive pulmonary disease. Am Rev Respir Dis 1987, 135: 907-911.CrossRefPubMed
30.
Zurück zum Zitat Austin MA, Wills KE, Blizzard L, Walters EH, Wood-Baker R: Effect of high flow oxygen on mortality in chronic obstructive pulmonary disease patients in pre-hospital setting: randomised controlled trial. BMJ 2010, 341: c5462. 10.1136/bmj.c5462PubMedCentralCrossRefPubMed Austin MA, Wills KE, Blizzard L, Walters EH, Wood-Baker R: Effect of high flow oxygen on mortality in chronic obstructive pulmonary disease patients in pre-hospital setting: randomised controlled trial. BMJ 2010, 341: c5462. 10.1136/bmj.c5462PubMedCentralCrossRefPubMed
31.
Zurück zum Zitat Watson NA, Beards SC, Altaf N, Kassner A, Jackson A: The effect of hyperoxia on cerebral blood flow: a study in healthy volunteers using magnetic resonance phase-contrast angiography. Eur J Anaesthesiol 2000, 17: 152-159.CrossRefPubMed Watson NA, Beards SC, Altaf N, Kassner A, Jackson A: The effect of hyperoxia on cerebral blood flow: a study in healthy volunteers using magnetic resonance phase-contrast angiography. Eur J Anaesthesiol 2000, 17: 152-159.CrossRefPubMed
32.
Zurück zum Zitat Floyd TF, Clark JM, Gelfand R, Detre JA, Ratcliffe S, Guvakov D, Lambertsen CJ, Eckenhoff RG: Independent cerebral vasoconstrictive effects of hyperoxia and accompanying arterial hypocapnia at 1 ATA. J Appl Physiol 2003, 95: 2453-2461.CrossRefPubMed Floyd TF, Clark JM, Gelfand R, Detre JA, Ratcliffe S, Guvakov D, Lambertsen CJ, Eckenhoff RG: Independent cerebral vasoconstrictive effects of hyperoxia and accompanying arterial hypocapnia at 1 ATA. J Appl Physiol 2003, 95: 2453-2461.CrossRefPubMed
33.
Zurück zum Zitat Rusyniak DE, Kirk MA, May JD, Kao LW, Brizendine EJ, Welch JL, Cordell WH, Alonso RJ: Hyperbaric oxygen therapy in acute ischemic stroke. Results of the Hyperbaric Oxygen in Acute Ischemic Stroke Trial Pilot Study. Stroke 2003, 34: 571-574. 10.1161/01.STR.0000050644.48393.D0CrossRefPubMed Rusyniak DE, Kirk MA, May JD, Kao LW, Brizendine EJ, Welch JL, Cordell WH, Alonso RJ: Hyperbaric oxygen therapy in acute ischemic stroke. Results of the Hyperbaric Oxygen in Acute Ischemic Stroke Trial Pilot Study. Stroke 2003, 34: 571-574. 10.1161/01.STR.0000050644.48393.D0CrossRefPubMed
34.
Zurück zum Zitat Bennett MH, Wasiak J, Schnabel A, Kranke P, French C: Hyperbaric oxygen therapy for acute ischaemic stroke. Cochrane Database Syst Rev 2005, 3: CD004954.PubMed Bennett MH, Wasiak J, Schnabel A, Kranke P, French C: Hyperbaric oxygen therapy for acute ischaemic stroke. Cochrane Database Syst Rev 2005, 3: CD004954.PubMed
35.
Zurück zum Zitat Padma MV, Bhasin A, Bhatia R, Garg A, Singh MB, Tripathi M, Prasad K: Normobaric oxygen therapy in acute ischemic stroke: a pilot study in Indian patients. Ann Indian Acad Neurol 2010, 13: 284-288. 10.4103/0972-2327.74203PubMedCentralCrossRefPubMed Padma MV, Bhasin A, Bhatia R, Garg A, Singh MB, Tripathi M, Prasad K: Normobaric oxygen therapy in acute ischemic stroke: a pilot study in Indian patients. Ann Indian Acad Neurol 2010, 13: 284-288. 10.4103/0972-2327.74203PubMedCentralCrossRefPubMed
36.
Zurück zum Zitat Ronning OM, Guldvog B: Should stroke victims routinely receive supplemental oxygen? A quasi-randomized controlled trial. Stroke 1999, 30: 2033-2037. 10.1161/01.STR.30.10.2033CrossRefPubMed Ronning OM, Guldvog B: Should stroke victims routinely receive supplemental oxygen? A quasi-randomized controlled trial. Stroke 1999, 30: 2033-2037. 10.1161/01.STR.30.10.2033CrossRefPubMed
38.
Zurück zum Zitat Adams HP Jr, del Zoppo G, Alberts MJ, Bhatt DL, Brass L, Furlan A, Grubb RL, Higashida RT, Jauch EC, Kidwell C, Lyden PD, Morgenstern LB, Qureshi AI, Rosenwasser RH, Scott PA, Wijdicks EF, American Heart Association/American Stroke Association Stroke Council; American Heart Association/American Stroke Association Clinical Cardiology Council; American Heart Association/American Stroke Association Cardiovascular Radiology and Intervention Council; Atherosclerotic Peripheral Vascular Disease Working Group; Quality of Care Outcomes in Research Interdisciplinary Working Group: Guidelines for the early management of adults with ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: The American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists. Circulation 2007, 115: e478-534. 10.1161/CIRCULATIONAHA.107.181486CrossRefPubMed Adams HP Jr, del Zoppo G, Alberts MJ, Bhatt DL, Brass L, Furlan A, Grubb RL, Higashida RT, Jauch EC, Kidwell C, Lyden PD, Morgenstern LB, Qureshi AI, Rosenwasser RH, Scott PA, Wijdicks EF, American Heart Association/American Stroke Association Stroke Council; American Heart Association/American Stroke Association Clinical Cardiology Council; American Heart Association/American Stroke Association Cardiovascular Radiology and Intervention Council; Atherosclerotic Peripheral Vascular Disease Working Group; Quality of Care Outcomes in Research Interdisciplinary Working Group: Guidelines for the early management of adults with ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: The American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists. Circulation 2007, 115: e478-534. 10.1161/CIRCULATIONAHA.107.181486CrossRefPubMed
39.
Zurück zum Zitat Hazinski MF, Nolan JP, Billi JE, Böttiger BW, Bossaert L, de Caen AR, Deakin CD, Drajer S, Eigel B, Hickey RW, Jacobs I, Kleinman ME, Kloeck W, Koster RW, Lim SH, Mancini ME, Montgomery WH, Morley PT, Morrison LJ, Nadkarni VM, O'Connor RE, Okada K, Perlman JM, Sayre MR, Shuster M, Soar J, Sunde K, Travers AH, Wyllie J, Zideman D: Part 1: Executive summary: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. Circulation 2010, 122: S250-275. 10.1161/CIRCULATIONAHA.110.970897CrossRefPubMed Hazinski MF, Nolan JP, Billi JE, Böttiger BW, Bossaert L, de Caen AR, Deakin CD, Drajer S, Eigel B, Hickey RW, Jacobs I, Kleinman ME, Kloeck W, Koster RW, Lim SH, Mancini ME, Montgomery WH, Morley PT, Morrison LJ, Nadkarni VM, O'Connor RE, Okada K, Perlman JM, Sayre MR, Shuster M, Soar J, Sunde K, Travers AH, Wyllie J, Zideman D: Part 1: Executive summary: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. Circulation 2010, 122: S250-275. 10.1161/CIRCULATIONAHA.110.970897CrossRefPubMed
40.
Zurück zum Zitat Kilgannon JH, Jones AE, Shapiro NI, Angelos MG, Milcarek B, Hunter K, Parillo JE, Trzeciak S, Emergency Medicine Shock Research Network (EMShockNet) Investigators: Association between arterial hyperoxia following resuscitation from cardiac arrest and in-hospital mortality. JAMA 2010, 303: 2165-2171. 10.1001/jama.2010.707CrossRefPubMed Kilgannon JH, Jones AE, Shapiro NI, Angelos MG, Milcarek B, Hunter K, Parillo JE, Trzeciak S, Emergency Medicine Shock Research Network (EMShockNet) Investigators: Association between arterial hyperoxia following resuscitation from cardiac arrest and in-hospital mortality. JAMA 2010, 303: 2165-2171. 10.1001/jama.2010.707CrossRefPubMed
41.
Zurück zum Zitat Kilgannon JH, Jones AE, Parillo JE, Dellinger RP, Milcared B, Hunter K, Shapiro NI, Trzeciak S, Emergency Medicine Shock Research Network (EMShockNet) Investigators: Relationship between supranormal oxygen tension and outcome resuscitation from cardiac arrest. Circulation 2011, 123: 2717-2722. 10.1161/CIRCULATIONAHA.110.001016CrossRefPubMed Kilgannon JH, Jones AE, Parillo JE, Dellinger RP, Milcared B, Hunter K, Shapiro NI, Trzeciak S, Emergency Medicine Shock Research Network (EMShockNet) Investigators: Relationship between supranormal oxygen tension and outcome resuscitation from cardiac arrest. Circulation 2011, 123: 2717-2722. 10.1161/CIRCULATIONAHA.110.001016CrossRefPubMed
42.
Zurück zum Zitat Janz DR, Hollenbeck RD, Pollock JS, McPherson JA, Rice TW: Hyperoxia is associated with increased mortality in patients treated with mild therapeutic hypothermia after sudden cardiac arrest. Crit Care Med 2012, 40: 3135-3139. 10.1097/CCM.0b013e3182656976PubMedCentralCrossRefPubMed Janz DR, Hollenbeck RD, Pollock JS, McPherson JA, Rice TW: Hyperoxia is associated with increased mortality in patients treated with mild therapeutic hypothermia after sudden cardiac arrest. Crit Care Med 2012, 40: 3135-3139. 10.1097/CCM.0b013e3182656976PubMedCentralCrossRefPubMed
43.
Zurück zum Zitat Bellomo R, Bailey M, Eastwood GM, Nichol A, Pilcher D, Hart GK, Reade MC, Egi M, Cooper JD: Study of Oxygen in Criticial Care (SOCC) Group. Arterial hyperoxia and in-hospital mortality after resuscitation from cardiac arrest. Crit Care 2011, 15: R90. 10.1186/cc10090PubMedCentralCrossRefPubMed Bellomo R, Bailey M, Eastwood GM, Nichol A, Pilcher D, Hart GK, Reade MC, Egi M, Cooper JD: Study of Oxygen in Criticial Care (SOCC) Group. Arterial hyperoxia and in-hospital mortality after resuscitation from cardiac arrest. Crit Care 2011, 15: R90. 10.1186/cc10090PubMedCentralCrossRefPubMed
44.
Zurück zum Zitat Kuisma M, Boyd J, Voipio V, Alaspää A, Roine RO, Rosenberg P: Comparison of 30 and the 100% inspired oxygen concentrations during early post-resuscitation period: a randomized controlled pilot study. Resuscitation 2006, 69: 199-206. 10.1016/j.resuscitation.2005.08.010CrossRefPubMed Kuisma M, Boyd J, Voipio V, Alaspää A, Roine RO, Rosenberg P: Comparison of 30 and the 100% inspired oxygen concentrations during early post-resuscitation period: a randomized controlled pilot study. Resuscitation 2006, 69: 199-206. 10.1016/j.resuscitation.2005.08.010CrossRefPubMed
45.
Zurück zum Zitat Calzia E, Asfar P, Hauser B, Ballestra C, Radermacher P, Georgieff M: Hyperoxia may be beneficial. Crit Care Med 2010, 38: S559-S568.CrossRefPubMed Calzia E, Asfar P, Hauser B, Ballestra C, Radermacher P, Georgieff M: Hyperoxia may be beneficial. Crit Care Med 2010, 38: S559-S568.CrossRefPubMed
46.
Zurück zum Zitat Rossi P, Tauzin L, Weiss M, Rostain JC, Sainty JM, Boussuges A: Could hyperoxic ventilation impair oxygen delivery in septic patients? Clin Physiol Funct Imaging 2007, 27: 180-184. 10.1111/j.1475-097X.2007.00732.xCrossRefPubMed Rossi P, Tauzin L, Weiss M, Rostain JC, Sainty JM, Boussuges A: Could hyperoxic ventilation impair oxygen delivery in septic patients? Clin Physiol Funct Imaging 2007, 27: 180-184. 10.1111/j.1475-097X.2007.00732.xCrossRefPubMed
47.
Zurück zum Zitat Reinhart K, Bloos F, Konig F, Bredle D, Hanneman L: Reversible decrease of oxygen consumption by hyperoxia. Chest 1991, 99: 690-694. 10.1378/chest.99.3.690CrossRefPubMed Reinhart K, Bloos F, Konig F, Bredle D, Hanneman L: Reversible decrease of oxygen consumption by hyperoxia. Chest 1991, 99: 690-694. 10.1378/chest.99.3.690CrossRefPubMed
48.
Zurück zum Zitat Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, Sevransky JE, Sprung CL, Douglas IS, Jaeschke R, Osborn TM, Nunally ME, Townsend SE, Reinhart K, Kleinpell RM, Angus DC, Deutschman CS, Machado FR, Rubenfeld GD, Webb S, Beale RJ, Vincent JL, Moreno R: Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock 2012. Intensive Care Med 2013, 39: 165-228. 10.1007/s00134-012-2769-8CrossRefPubMed Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, Sevransky JE, Sprung CL, Douglas IS, Jaeschke R, Osborn TM, Nunally ME, Townsend SE, Reinhart K, Kleinpell RM, Angus DC, Deutschman CS, Machado FR, Rubenfeld GD, Webb S, Beale RJ, Vincent JL, Moreno R: Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock 2012. Intensive Care Med 2013, 39: 165-228. 10.1007/s00134-012-2769-8CrossRefPubMed
49.
Zurück zum Zitat Dyson A, Stidwill R, Taylor V, Singer M: The impact of inspired oxygen concentration on tissue oxygenation during progressive haemorrhage. Intensive Care Med 2009, 35: 1783-1791. 10.1007/s00134-009-1577-2CrossRefPubMed Dyson A, Stidwill R, Taylor V, Singer M: The impact of inspired oxygen concentration on tissue oxygenation during progressive haemorrhage. Intensive Care Med 2009, 35: 1783-1791. 10.1007/s00134-009-1577-2CrossRefPubMed
50.
Zurück zum Zitat Task Force for Diagnosis and Treatment of Acute and Chronic Heart Failure 2008 of European Society of Cardiology, Dickstein K, Cohen-Solal A, Filippatos G, McMurray JJ, Ponikowski P, Poole-Wilson PA, Strömberg A, van Veldhuisen DJ, Atar D, Hoes AW, Keren A, Mebazaa A, Nieminen M, Priori SG, Swedberg K, ESC Committee for Practice Guidelines, Vahanian A, Camm J, De Caterina R, Dean V, Dickstein K, Filippatos G, Funck-Brentano C, Hellemans I, Kristensen SD, McGregor K, Sechtem U, Silber S, Tendera M, Widimsky P, Zamorano JL: ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008: the Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2008 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association of the ESC (HFA) and endorsed by the European Society of Intensive Care Medicine (ESICM). Eur Heart J 2008, 29: 2388-2442.CrossRef Task Force for Diagnosis and Treatment of Acute and Chronic Heart Failure 2008 of European Society of Cardiology, Dickstein K, Cohen-Solal A, Filippatos G, McMurray JJ, Ponikowski P, Poole-Wilson PA, Strömberg A, van Veldhuisen DJ, Atar D, Hoes AW, Keren A, Mebazaa A, Nieminen M, Priori SG, Swedberg K, ESC Committee for Practice Guidelines, Vahanian A, Camm J, De Caterina R, Dean V, Dickstein K, Filippatos G, Funck-Brentano C, Hellemans I, Kristensen SD, McGregor K, Sechtem U, Silber S, Tendera M, Widimsky P, Zamorano JL: ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008: the Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2008 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association of the ESC (HFA) and endorsed by the European Society of Intensive Care Medicine (ESICM). Eur Heart J 2008, 29: 2388-2442.CrossRef
51.
Zurück zum Zitat Anderson JL, Adams CD, Antman EM, Bridges CR, Califf RM, Casey DE Jr, Chavey WE, Fesmire FM, Hochman JS, Levin TN, Lincoff AM, Peterson ED, Theroux P, Wenger NK, Wright RS, Smith SC Jr, Jacobs AK, Adams CD, Anderson JL, Antman EM, Halperin JL, Hunt SA, Krumholz HM, Kushner FG, Lytle BW, Nishimura R, Ornato JP, Page RL, Riegel B, American College of Cardiology; American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines for the Management of Patients With Unstable Angina/Non-ST-Elevation Myocardial Infarction); American College of Emergency Physicians; Society for Cardiovascular Angiography and Interventions; Society of Thoracic Surgeons; American Association of Cardiovascular and Pulmonary Rehabilitation; Society for Academic Emergency Medicine: ACC/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-Elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines for the Management of Patients With Unstable Angina/Non-ST-Elevation Myocardial Infarction) developed in collaboration with the American College of Emergency Physicians, the Society for Cardiovascular Angiography and Interventions, and the Society of Thoracic Surgeons endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation and the Society for Academic Emergency Medicine. J Am Coll Cardiol 2007, 50: e1-e157.CrossRefPubMed Anderson JL, Adams CD, Antman EM, Bridges CR, Califf RM, Casey DE Jr, Chavey WE, Fesmire FM, Hochman JS, Levin TN, Lincoff AM, Peterson ED, Theroux P, Wenger NK, Wright RS, Smith SC Jr, Jacobs AK, Adams CD, Anderson JL, Antman EM, Halperin JL, Hunt SA, Krumholz HM, Kushner FG, Lytle BW, Nishimura R, Ornato JP, Page RL, Riegel B, American College of Cardiology; American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines for the Management of Patients With Unstable Angina/Non-ST-Elevation Myocardial Infarction); American College of Emergency Physicians; Society for Cardiovascular Angiography and Interventions; Society of Thoracic Surgeons; American Association of Cardiovascular and Pulmonary Rehabilitation; Society for Academic Emergency Medicine: ACC/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-Elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines for the Management of Patients With Unstable Angina/Non-ST-Elevation Myocardial Infarction) developed in collaboration with the American College of Emergency Physicians, the Society for Cardiovascular Angiography and Interventions, and the Society of Thoracic Surgeons endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation and the Society for Academic Emergency Medicine. J Am Coll Cardiol 2007, 50: e1-e157.CrossRefPubMed
52.
Zurück zum Zitat O'Driscoll R, Davison A, Elliott M, Howard L, Wedzicha J, Mackway-Jones K, Jenkins P, Kishen R, Levy M, Perrott S, Mansfield L, Evans A, Panizzo S, Moore F, Whitmore D, Gibbs S, Martin B, Hinshaw K: BTS guideline for emergency oxygen use in adult patients. Thorax 2008,63(Suppl 6):vi1-68.PubMed O'Driscoll R, Davison A, Elliott M, Howard L, Wedzicha J, Mackway-Jones K, Jenkins P, Kishen R, Levy M, Perrott S, Mansfield L, Evans A, Panizzo S, Moore F, Whitmore D, Gibbs S, Martin B, Hinshaw K: BTS guideline for emergency oxygen use in adult patients. Thorax 2008,63(Suppl 6):vi1-68.PubMed
53.
Zurück zum Zitat Hopkins RO, Weaver LK, Pope D, Orme JF, Bigler ED, Larson-Lohr V: Neuropsychological sequelae and impaired health status in survivors of severe acute respiratory distress syndrome. Am J Respir Crit Care Med 1999, 160: 50-56. 10.1164/ajrccm.160.1.9708059CrossRefPubMed Hopkins RO, Weaver LK, Pope D, Orme JF, Bigler ED, Larson-Lohr V: Neuropsychological sequelae and impaired health status in survivors of severe acute respiratory distress syndrome. Am J Respir Crit Care Med 1999, 160: 50-56. 10.1164/ajrccm.160.1.9708059CrossRefPubMed
54.
Zurück zum Zitat Gupta AK, Menon DK, Czosnyka M, Smielewsky P, Jones JG: Thresholds for hypoxic cerebral vasodilation in volunteers. Anesth Analg 1997, 85: 817-820.PubMed Gupta AK, Menon DK, Czosnyka M, Smielewsky P, Jones JG: Thresholds for hypoxic cerebral vasodilation in volunteers. Anesth Analg 1997, 85: 817-820.PubMed
55.
Zurück zum Zitat Bulte DP, Chiarelli PA, Wise RG, Jezzard P: Cerebral perfusion response to hyperoxia. J Cereb Blood Flow Metab 2007, 27: 69-75. 10.1038/sj.jcbfm.9600319CrossRefPubMed Bulte DP, Chiarelli PA, Wise RG, Jezzard P: Cerebral perfusion response to hyperoxia. J Cereb Blood Flow Metab 2007, 27: 69-75. 10.1038/sj.jcbfm.9600319CrossRefPubMed
56.
Zurück zum Zitat Brenner M, Stein D, Hu P, Kufera J, Wooford M, Scalea T: Association between early hyperoxia and worse outcomes after traumatic brain injury. Arch Surg 2012, 147: 1042-1046.CrossRefPubMed Brenner M, Stein D, Hu P, Kufera J, Wooford M, Scalea T: Association between early hyperoxia and worse outcomes after traumatic brain injury. Arch Surg 2012, 147: 1042-1046.CrossRefPubMed
57.
Zurück zum Zitat Lumb AB: Nunn's Applied Respiratory Physiology. 7th edition. New York: Churchill Livingstone; 2010. Lumb AB: Nunn's Applied Respiratory Physiology. 7th edition. New York: Churchill Livingstone; 2010.
58.
Zurück zum Zitat Manning HL, Schwartzstein RM: Pathophysiology of dyspnea. N Engl J Med 1995, 333: 1547-1553. 10.1056/NEJM199512073332307CrossRefPubMed Manning HL, Schwartzstein RM: Pathophysiology of dyspnea. N Engl J Med 1995, 333: 1547-1553. 10.1056/NEJM199512073332307CrossRefPubMed
59.
Zurück zum Zitat Cranston JM, Crockett A, Currow D: Oxygen therapy for dyspnoea in adults. Cochrane Database Syst Rev 2008, 3: CD004769.PubMed Cranston JM, Crockett A, Currow D: Oxygen therapy for dyspnoea in adults. Cochrane Database Syst Rev 2008, 3: CD004769.PubMed
60.
Zurück zum Zitat Abernethy AP, McDonald CF, Frith PA, Clark K, Herndon JE, Marcello J, Young IH, Bull J, Wilcock A, Booth S, Wheeler JL, Tulsky JA, Crocket AJ, Currow DC: Effect of palliative oxygen versus room air in relief of breathlessness in patients with refractory dyspnea: a double-blind, randomized controlled trial. Lancet 2010, 376: 784-793. 10.1016/S0140-6736(10)61115-4PubMedCentralCrossRefPubMed Abernethy AP, McDonald CF, Frith PA, Clark K, Herndon JE, Marcello J, Young IH, Bull J, Wilcock A, Booth S, Wheeler JL, Tulsky JA, Crocket AJ, Currow DC: Effect of palliative oxygen versus room air in relief of breathlessness in patients with refractory dyspnea: a double-blind, randomized controlled trial. Lancet 2010, 376: 784-793. 10.1016/S0140-6736(10)61115-4PubMedCentralCrossRefPubMed
61.
Zurück zum Zitat Osler W: The Principles and Practice of Medicine. 3rd edition. New York: D. Appleton and Company; 1898. Osler W: The Principles and Practice of Medicine. 3rd edition. New York: D. Appleton and Company; 1898.
Metadaten
Titel
The potential harm of oxygen therapy in medical emergencies
verfasst von
Alexander D Cornet
Albertus J Kooter
Mike JL Peters
Yvo M Smulders
Publikationsdatum
01.04.2013
Verlag
BioMed Central
Erschienen in
Critical Care / Ausgabe 2/2013
Elektronische ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc12554

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