Introduction
Background
Method
Study Setting, design and population
Data collection method
Socio-demographic and clinical data collection
Blood collection and laboratory analysis
Data quality control
Statistical analysis
Results
Sociodemographic and obstetric data of study participants
Variable | Frequency | Percentage (%) | |
---|---|---|---|
Gender | Male | 75 | 49.7 |
Female | 76 | 50.3 | |
Residence of mother | Urban | 132 | 87.4 |
Rural | 19 | 12.6 | |
Occupation of the mother | Employed | 54 | 35.8 |
House wife | 57 | 64.2 | |
Birth weight | Normal ( > = 2.5 kg) | 136 | 90.1 |
Under birth (< 2.5 k.g) | 15 | 9.9 | |
Gravidia | Primigravidia | 65 | 43 |
Multigravidia | 86 | 57 |
Hematological parameter | Sex | Delivery type | ||||
---|---|---|---|---|---|---|
Male | Female | P-value | Vaginal | Cesarean | p-value | |
WBC(x109/l) | 12.6 | 13.15 | 0.98 | 12.6 | 13.1 | 0.64 |
RBC(x1012/l) | 4.7 | 4.6 | 0.51 | 4.61 | 4.73 | 0.27 |
Hgb (g/dl) | 16.2 | 15.75 | 0.47 | 15.8 | 16.6 | 0.09 |
Hct (%) | 49.6 | 48.65 | 0.44 | 48.6 | 50.45 | 0.05 |
Platelet (x109/l) | 292 | 271 | 0.17 | 276 | 274 | 0.62 |
Lymphocyte absolute (x109/l) | 4.5 | 4.6 | 0.12 | 4.6 | 4.55 | 0.91 |
Neutrophil absolute ((x109/l) | 6.4 | 7.25 | 0.19 | 7 | 6.95 | 0.57 |
Hematological reference interval
Hematological parameter | Median (IQR) | Lower limit (2.5th ) | Upper limit (97.5th ) | RI (95th percentile) |
---|---|---|---|---|
Total WBC (x109/l) | 12.8 (10.5–15.4) | 7.64 | 22.16 | 7.64–22.16 |
RBC (x1012/l) | 4.64 (4.25–4.89) | 3.69 | 5.47 | 3.69–5.47 |
Hgb (g/dl) | 16 (14.8–17) | 13.32 | 19.64 | 13.32–19.64 |
Hct (%) | 49.1 (44.9–51.8) | 39.42 | 58.06 | 39.42–58.06 |
MCV (fl.) | 105.85 (102.6-109.6) | 91.6 | 113.22 | 91.6-113.22 |
MCH (pg) | 35 (33.7–35.7) | 30.48 | 38.02 | 30.48–38.02 |
MCHC (g/dl) | 33.1 (32.5–33.5) | 31.48 | 36.5 | 31.48–36.5 |
Platelet (x109/l) | 276 (233–314) | 132.74 | 413.4 | 132.74–413.4 |
Lymphocyte percentage (%) | 35.9 (30–41) | 14.22 | 58.32 | 14.22–58.32 |
Mix percentage (%) | 10.3 (7.9–12.5) | 3.34 | 18.64 | 3.34–18.64 |
Neutrophil percentage (%) | 53.5 (48.5–60.7) | 36.74 | 79.48 | 36.74–79.48 |
Lymphocyte absolute (x109/l) | 4.6 (3.6–5.5) | 2.16 | 10.3 | 2.16–10.3 |
Mix absolute (x109/l) | 1.3 (0.9–1.7) | 0.4 | 2.94 | 0.4–2.94 |
Neutrophil absolute (x109/l) | 7 (5.4–8.9) | 2.96 | 13.54 | 2.96–13.54 |
RDW-SD | 68.1 (64.7–72.1) | 55.48 | 81.3 | 55.48–81.3 |
Platelet distribution width (PDW) | 11.3 (10.5–12.2) | 8.8 | 15.68 | 8.8-15.68 |
Mean platelet volume (MPV) | 9.5 (9.1–10) | 7.88 | 11.04 | 7.88–11.04 |
Discussion
Hematological parameter | RI | |||||||
---|---|---|---|---|---|---|---|---|
Northwest Ethiopia (N = 151) | Saudi Arabia (N = 2163) [20] | Nepal (N = 210) [21] | Pakistan (N = 316) [25] | Lagos, Nigeria (N = 130 [17] | Mashhad, Iran (N = 447) [22] | Iraq (N = 220) [26] | Sagamu, Nigeria (N = 108) [23] | |
Total WBC | 7.64–22.16 | 10.9–21.5 | 10.49–19.4 | 9.7–17.7 | 7.9–18.3 | 5.16–18.2 | 7.32–12.92 | 4.2–25.8 |
RBC | 3.69–5.47 | 5.1–16.3 | 3.67–4.93 | - | 3.52–4.62 | 3.61–5.29 | 3.53–4.47 | 4.3–5.9 |
Hgb | 13.3–19.6 | 15.7–19.7 | 13.28–17.2 | 13.5–17.3 | 11.8–14.8 | 13-18.8 | 12.3-15.22 | 13-17.8 |
Hct | 39.4–58.1 | 46.9–59.5 | - | - | 39-50.6 | 39.6–56.9 | 39.7–49.2 | 39.1–53.5 |
MCV | 91.6-113.2 | 97.9-112.3 | 95.2-107.2 | 103.8–108 | 98.5-122.2 | 97.5-119.8 | 105.5-117.7 | 84.4–98.8 |
MCH | 30.5-38.02 | 30.2–40.6 | 31.6–36.2 | 32.2–35.4 | 28.5–36.7 | 31.7–40 | 32.1–36.8 | 27.9–33.1 |
MCHC | 31.48–36.5 | 27-40.2 | 31.7–34.9 | - | 28.1–31.4 | 30.1–35.2 | 29.03–32.86 | 31.7–34.5 |
Platelet | 132.7–413 | 178.2–297 | 165.6-288.2 | 223–347 | 152.9-297.3 | 131–383 | 207–328 | 129–607 |
Lymphocyte % | 14.2–58.3 | 16.5–37.1 | 23.7–46.7 | - | - | - | 29.6-49.98 | 27.8–49.6 |
Neutrophil percentage | 36.7–79.5 | 50.3–74.1 | 51.5–74.7 | - | - | - | 39.8–62.2 | 45.9–67.7 |
Lymphocyte absolute | 2.16–10.3 | - | - | 3.3–6.9 | - | 1.14–8.46 | - | - |
Neutrophil absolute | 2.96–13.54 | - | - | 4.7–10.7 | - | 1.12–10.2 | - | - |