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Erschienen in: Acta Neuropathologica Communications 1/2022

Open Access 01.12.2022 | Correction

Correction: High-resolution transcriptomics informs glial pathology in human temporal lobe epilepsy

verfasst von: Balagopal Pai, Jessica Tome‑Garcia, Wan Sze Cheng, German Nudelman, Kristin G. Beaumont, Saadi Ghatan, Fedor Panov, Elodia Caballero, Kwadwo Sarpong, Lara Marcuse, Jiyeoun Yoo, Yan Jiang, Anne Schaefer, Schahram Akbarian, Robert Sebra, Dalila Pinto, Elena Zaslavsky, Nadejda M. Tsankova

Erschienen in: Acta Neuropathologica Communications | Ausgabe 1/2022

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The original article can be found online at https://​doi.​org/​10.​1186/​s40478-022-01453-1.

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Correction to: Acta Neuropathologica Communications (2022) 10:149 https://​doi.​org/​10.​1186/​s40478-022-01453-1
Following publication of the original article [1], the authors identified an error in Table 1 due to a typesetting mistake. The correctly formatted table is given below and the original article has been corrected.
Table 1
Sample information
Sample ID
Tissue, location
Age, Gender PMT
Nuclei RNA-SEQ
SC RNA-SEQ
Pathological diagnosis
Cell-type specific FANS Validation, TL vs. TLE
10,662
TL control, temporal lobe neocortex
34yo, M
12 h PMT
 
No neuropathological changes seen in cortex
10,355
TL control, temporal lobe neocortex
45yo, F
12 h PMT
 
No neuropathological changes seen in cortex
10,997
TL control, temporal lobe neocortex
27yo, M
21 h PMT
 
No neuropathological changes seen in cortex
12,321
TLE, temporal lobe neocortex
50yo, M
 
Cortical and Chaslin Gliosis; White matter neuronal heterotopia
10,308
TLE, temporal lobe neocortex
29yo, F
 
Cortical and Chaslin gliosis; FCD Ia
12,726
TLE, temporal lobe neocortex
13yo, M
 
Cortex without pathologic changes; *
14,431
TLE, temporal lobe neocortex
28yo, M
 
(10X, v2)
Cortical Gliosis; Ectopic white matter neurons with mild hypertrophy;
19,619
TLE, temporal lobe neocortex
31yo, F
 
(10X, v2)
Chaslin gliosis; *
20,188
TLE, temporal lobe neocortex
58yo, F
 
(10X, v3)
Cortical and Chaslin gliosis, rare neurons with hypertrophy and disoriented dendrites; *
12,814
TLE, temporal lobe neocortex
11yo, M
 
(10X, v1)
Chaslin gliosis; *
13,059
TLE, temporal lobe neocortex
8yo, M
 
(10X, v1)
Gliosis, neuronal heterotopia;
Sample ID
Tissue, location
Age, Gender
Ki-67 IF
In vitro assays
Pathological diagnosis
Phenotypic analysis of epilepsy glia
12,321
TLE, temporal lobe neocortex
50yo, M
✓’ (high)
Cortical and Chaslin Gliosis; White matter neuronal heterotopia;
10,308
TLE, temporal lobe neocortex
29yo, F
✓(low)
Cortical and Chaslin gliosis; FCD Ia;
12,726
TLE, temporal lobe neocortex
13yo, M
✓’ (high)
 
Cortex without pathologic changes; *
14,431
TLE, temporal lobe neocortex
28yo, M
✓(low)
Cortical Gliosis; Ectopic white matter neurons with mild hypertrophy;
12,319
Epilepsy, frontal lobe neocortex
27yo, M
✓’ (high)
 
Chaslin Gliosis; Ischemic changes
12,433
Epilepsy, TS, frontal lobe neocortex
4yo, M
✓(low)
Cortical and Chaslin Gliosis; **
PMT Postmortem time, IF Immunofluorescence, M Male, F Female, yo years old; h hours; TS Tuberous sclerosis. FCD Focal cortical dysplasia
*Hippocampal sclerosis seen away from the sampled area, **Tubers seen away from the sampled area.’ Samples included in the IF analysis of Ki67 proliferation cell type distribution
In addition, the authors corrected the ‘Availability of data and materials’ section.
The statement in the ‘Availability of data and materials’ section originally read: The data that support the findings in this study are publicly available at https://​data.​mendeley.​com/​drafts/​w4d7sdc629, and are currently being deposited in NCBI’s Gene Expression Omnibus to be accessible through a GEO Series accession number GSE140393 prior to publication.
The statement in the ‘Availability of data and materials’ section should read: The data that support the findings in this study are publicly available in NCBI’s Gene Expression Omnibus through a GEO Series accession number GSE140393.
Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://​creativecommons.​org/​licenses/​by/​4.​0/​. The Creative Commons Public Domain Dedication waiver (http://​creativecommons.​org/​publicdomain/​zero/​1.​0/​) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Correction: High-resolution transcriptomics informs glial pathology in human temporal lobe epilepsy
verfasst von
Balagopal Pai
Jessica Tome‑Garcia
Wan Sze Cheng
German Nudelman
Kristin G. Beaumont
Saadi Ghatan
Fedor Panov
Elodia Caballero
Kwadwo Sarpong
Lara Marcuse
Jiyeoun Yoo
Yan Jiang
Anne Schaefer
Schahram Akbarian
Robert Sebra
Dalila Pinto
Elena Zaslavsky
Nadejda M. Tsankova
Publikationsdatum
01.12.2022
Verlag
BioMed Central
Erschienen in
Acta Neuropathologica Communications / Ausgabe 1/2022
Elektronische ISSN: 2051-5960
DOI
https://doi.org/10.1186/s40478-022-01479-5

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