Erschienen in:
Open Access
01.04.2013 | Poster presentation
Treatment-related cardiac complications associated with goal-directed therapy in high-risk surgical patients: a meta-analysis
verfasst von:
N Arulkumaran, C Corredor, M Hamilton, M Grounds, J Ball, A Rhodes, M Cecconi
Erschienen in:
Critical Care
|
Sonderheft 2/2013
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Excerpt
We hypothesized that goal-directed therapy (GDT) is not associated with an increased risk of cardiac complications in high-risk, noncardiac surgical patients. Patients with limited cardiopulmonary reserve are at risk of mortality and morbidity after major surgery [
1]. Augmentation of the oxygen delivery index (DO
2I) with a combination of intravenous fluids and inotropes (GDT) has been shown to reduce the postoperative mortality and morbidity in high-risk patients [
2]. However, concerns regarding cardiac complications associated with fluid challenges and inotropes used to augment cardiac output may deter clinicians from instituting early GDT in the very patients who are more likely to benefit. …