Background
Materials and methods
Literature search strategy
Inclusion criteria
Exclusion criteria
Data extraction
Quality assessment
Statistical analysis
Results
Summary of literature search and study selection
Author and Year | Study population | Participants (T/C) | Intervention | Study duration | Parameters | Main results |
---|---|---|---|---|---|---|
Miele 2017 | CKD 3 | 46(25/21) | Aerobic exercise three times a week | 16 Weeks | eGFR; TC; TG LDL; HDL; BMI | No significant difference in eGFR between the two groups |
Hiraki 2017 | CKD3–4 | 28(14/14) | Aerobic and resistance exercise | 12 Months | eGFR | No significant difference in eGFR between the two groups |
Kiuchi 2017 | CKD3–5 | 40(20/20) | Moderate exercise, 150 min a week, gradually increasing to 300 min a week | 12 Months | eGFR; SCr; Blood pressure | Decreased SCr; Improved eGFR |
Leehey 2016 | CKD 2–4 | 32(14/18) | Aerobic and resistance exercises three days a week lasted for 12 weeks, followed by Home-based exercises for 40 weeks. | 12 Weeks 52 Weeks | eGFR; Systolic blood pressure; TC; TG LDL; HDL; BMI | NO change eGFR, systolic blood pressure and blood lipid both after 12 and 52 Weeks |
Aoike 2015 | CKD3–4 | 29(14/15) | Aerobic exercise, 3 times a week | 12 weeks | GFR; SCr; Blood pressure; BMI | Decreased blood pressure and improved renal function |
Greenwood 2015 | CKD3–4 | 18(8/10) | Aerobic and resistance exercises, 3 days a week | 6 Months 12 Months | eGFR; SCr; Blood pressure; TC; LDL; HDL; BMI | eGFR increased slightly after 6 months, Improvement mean rate of change in eGFR and SCr after 12 months, but no change blood pressure, blood lipid and creatinine |
Howden 2015 | CKD3–4 | 72(36/36) | Aerobic and resistance exercises, 150 min a week | 6 Months 12 Months | eGFR; SCr; Blood pressure; TC; LDL; HDL; BMI | NO change in eGFR and blood pressure after both 6 and 12 Months |
Van Craenenbroeck 2015 | CKD3–4 | 40(19/21) | Home-based aerobic exercises,4 times a day, 10 min each time | 3 Months | eGFR; Blood pressure; TC; LDL; HDL; BMI | NO improvement in eGFR and blood pressure |
Baria 2014 | CKD3–4 | 19(10/9) | Aerobic exercise, 3 times a week | 12 Weeks | eGFR; Blood pressure; BMI | Decreased Blood pressure and improved eGFR |
Headley 2014 | CKD 3 | 46(25/21) | Aerobic exercise, 3 times a week | 16 Weeks | Blood pressure; BMI | NO change in blood pressure |
Headley 2012 | CKD2–4 | 21(10/11) | Aerobic exercise, 3 times a week for 24 weeks, followed by resistance exercise, 2 times a week for 24 weeks | 24 Weeks 48 Weeks | eGFR; Blood pressure; TC; TG LDL; HDL; BMI | TG increased at 24 weeks, but no change at 48 weeks. TC and LDL increased at 24 and 48 weeks, but no change eGFR, blood pressure and HDL |
Toyama 2010 | CKD2–4 | 19(10/9) | Aerobic exercise once a week | 12 Weeks | eGFR | Increased eGFR |
Leehey 2009 | CKD2–4 | 11(7/4) | Aerobic exercise, 3 times a week for 6 weeks, followed by home-based exercise for 18 weeks | 6 Weeks 24 Weeks | eGFR; SCr; Blood pressure; TC; TG; LDL; HDL | Systolic blood pressure decreased slightly at 6 weeks, but GFR, blood lipid and blood pressure did not improve; no improvement between the two groups at 24 weeks |