Background
Methods
Study Population
Edmondson-Steiner grade | |
---|---|
I | Cells with abundant cytoplasm and minimal nuclear irregularity |
II | Greater nuclear irregularity and prominent nucleoli |
III | Increased nuclear pleomorphism and angulation of the nuclei; Tumour giant cells were also more commonly seen |
IVa | Poorly differentiated with marked nuclear pleomorphism, hyperchromatism and anaplasia |
MR imaging protocol
Sequence | TR(ms) | TE(ms) | FA | Scan time (s) | Slice thickness (mm) | Matrix | FOV |
---|---|---|---|---|---|---|---|
Plain scan | |||||||
T1WI | 225 | 2.2 | 70 | 19.42 | 6 | 200 × 320 | 258 × 330 |
T2WI | 2000 | 91 | 150 | 106 | 6 | 410 × 512 | 350 × 350 |
VIBE-T1mapping | 4.4 | 1.2 | 2,12 | 20.15 | 2 | 154 × 256 | 248 × 330 |
DCE | |||||||
VIBE | 3.3 | 1.2 | 13 | 8.21/phase | 2 | 96 × 256 | 248 × 330 |
Hepatobiliary-phase | |||||||
T1WI | 225 | 2.2 | 70 | 19.42 | 6 | 200 × 320 | 258 × 330 |
VIBE-T1mapping | 4.4 | 1.2 | 2,12 | 20.15 | 2 | 154 × 256 | 248 × 330 |
Image analysis
Statistical analysis
Results
Size
Edmondson-Steiner grade | No. | Diameters (mean, mm)a |
---|---|---|
I | 13 | 31.3 ± 23.7 |
II | 27 | 25.4 ± 23.5 |
III | 13 | 38.8 ± 35.6 |
Total | 53 | 30.1 ± 28.5 |
Comparison of T1mapping for HCC in different Edmondson-Steiner grade
Correlation analysis
T1p | T1e | T1d | T1d % | |
---|---|---|---|---|
Correlation index | −0.065 | 0.335 | −0.570 | −0.676a |
P | 0.643 | 0.014 | 0.000 | 0.000 |
N | 53 | 53 | 53 | 53 |