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Erschienen in: Sports Medicine 8/2004

01.07.2004 | Leading Article

The Benefits of Exercise Training for Quality of Life in HIV/AIDS in the Post-HAART Era

verfasst von: Joseph T. Ciccolo, Esbelle M. Jowers, John B. Bartholomew

Erschienen in: Sports Medicine | Ausgabe 8/2004

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Abstract

The use of highly active antiretroviral therapy (HAART) has served to significantly reduce the mortality of HIV-infected persons. However, this treatment is associated with a host of adverse effects: fatigue, nausea, pain, anxiety and depression. Rather than utilise traditional pharmacological treatments for these effects, many HIV/AIDS patients are utilising adjunct therapies to maintain their quality of life while they undergo treatment. Exercise has consistently been listed as one of the most popular self-care therapies and a small number of studies have been conducted to examine the impact of exercise on the most common self-reported symptoms of HIV and AIDS and the adverse effects of treatment. Although the results are generally positive, there are clear limitations to this work. The existing studies have utilised small samples and experienced high rates of attrition. In addition, the majority of the studies were conducted prior to the widespread use of HAART, which limits the ability to generalise these data. As a result, data from other chronic disease and healthy samples are used to suggest that exercise has the potential to be a beneficial treatment across the range of symptoms and adverse effects experienced by HIV-infected individuals. However, additional research is required with this population to demonstrate these effects.
Literatur
1.
Zurück zum Zitat Nuesch R, Geigy N, Schaedler E, et al. Effect of highly active antiretroviral therapy on hospitalization characteristics of HIV-infected patients. Eur J Clin Microbiol Infect Dis 2002; 21: 684–7PubMed Nuesch R, Geigy N, Schaedler E, et al. Effect of highly active antiretroviral therapy on hospitalization characteristics of HIV-infected patients. Eur J Clin Microbiol Infect Dis 2002; 21: 684–7PubMed
2.
Zurück zum Zitat Palella Jr FJ, Chmiel JS, Moorman AC, et al. The HIV Outpatient Study Investigators. Durability and predictors of success of highly active antiretroviral therapy for ambulatory HIV-infected patients. AIDS 2002; 16: 1617–26 Palella Jr FJ, Chmiel JS, Moorman AC, et al. The HIV Outpatient Study Investigators. Durability and predictors of success of highly active antiretroviral therapy for ambulatory HIV-infected patients. AIDS 2002; 16: 1617–26
3.
Zurück zum Zitat Miller V, Sabin CA, Phillips AN, et al. The impact of protease inhibitor-containing highly active antiretroviral therapy on progression of HIV disease and its relationship to CD4 and viral load. AIDS 2000; 14: 2129–36PubMed Miller V, Sabin CA, Phillips AN, et al. The impact of protease inhibitor-containing highly active antiretroviral therapy on progression of HIV disease and its relationship to CD4 and viral load. AIDS 2000; 14: 2129–36PubMed
4.
Zurück zum Zitat Porter K. Survival after introduction of HAART in people with known duration of HIV-1 infection. Lancet 2000; 355: 1158–9 Porter K. Survival after introduction of HAART in people with known duration of HIV-1 infection. Lancet 2000; 355: 1158–9
5.
Zurück zum Zitat Hicks C, Currier J, Sax P, et al. Current management challenges in HIV: tolerability of antiretrovirals and metabolic complications. AIDS Patient Care STDS 2003; 17: 221–33PubMed Hicks C, Currier J, Sax P, et al. Current management challenges in HIV: tolerability of antiretrovirals and metabolic complications. AIDS Patient Care STDS 2003; 17: 221–33PubMed
6.
Zurück zum Zitat Horwath E. Psychiatric and neuropsychiatric manifestations of HIV infection. J Int Assoc Physicians AIDS Care 2002; 1Suppl. 1: S3–15 Horwath E. Psychiatric and neuropsychiatric manifestations of HIV infection. J Int Assoc Physicians AIDS Care 2002; 1Suppl. 1: S3–15
7.
Zurück zum Zitat Roberts KJ. Barriers to and facilitators of HIV-positive patients’ adherence to antiretroviral treatment regimes. AIDS Patient Care STDS 2000; 14: 155–68PubMed Roberts KJ. Barriers to and facilitators of HIV-positive patients’ adherence to antiretroviral treatment regimes. AIDS Patient Care STDS 2000; 14: 155–68PubMed
8.
Zurück zum Zitat Stone VE. Strategies for optimizing adherence to highly active antiretroviral therapy: lessons from research and clinical practice. Clin Infect Dis 2001; 33: 865–72PubMed Stone VE. Strategies for optimizing adherence to highly active antiretroviral therapy: lessons from research and clinical practice. Clin Infect Dis 2001; 33: 865–72PubMed
9.
Zurück zum Zitat Cinti SK. Adherence to antiretrovirals in HIV disease. AIDS Readings 2000; 10: 709–17 Cinti SK. Adherence to antiretrovirals in HIV disease. AIDS Readings 2000; 10: 709–17
10.
Zurück zum Zitat Chesney MA. Factors affecting adherence to antiretroviral therapy. Clin Infect Dis 2000; 30Suppl. 2: 171S–6 Chesney MA. Factors affecting adherence to antiretroviral therapy. Clin Infect Dis 2000; 30Suppl. 2: 171S–6
11.
Zurück zum Zitat Chesney M. Adherence to HAART regimens. AIDS Patient Care STDS 2003; 17: 169–77PubMed Chesney M. Adherence to HAART regimens. AIDS Patient Care STDS 2003; 17: 169–77PubMed
12.
Zurück zum Zitat Press N, Tyndall MW, Wood E, et al. Virologic and immunologic response, clinical progression, and highly active antiretroviral therapy adherence. J Acquir Immune Defic Syndr 2002; 31Suppl. 3: S112–7PubMed Press N, Tyndall MW, Wood E, et al. Virologic and immunologic response, clinical progression, and highly active antiretroviral therapy adherence. J Acquir Immune Defic Syndr 2002; 31Suppl. 3: S112–7PubMed
13.
Zurück zum Zitat Duggan J, Peterson WS, Schultz M, et al. Use of complementary and alternative therapies in HIV-infected patients. AIDS Patient Care STDS 2001; 15: 159–67PubMed Duggan J, Peterson WS, Schultz M, et al. Use of complementary and alternative therapies in HIV-infected patients. AIDS Patient Care STDS 2001; 15: 159–67PubMed
14.
Zurück zum Zitat Standish LJ, Greene KB, Bain S, et al. Alternative medicine use in HIV-positive men and women: demographics, utilization patterns and health status. AIDS Care 2001; 13: 197–208PubMed Standish LJ, Greene KB, Bain S, et al. Alternative medicine use in HIV-positive men and women: demographics, utilization patterns and health status. AIDS Care 2001; 13: 197–208PubMed
15.
Zurück zum Zitat Sparber A, Wootton JC, Bauer L, et al. Use of complementary medicine by adult patients participating in HIV/AIDS clinical trials. J Altern Complement Med 2000; 6: 415–22PubMed Sparber A, Wootton JC, Bauer L, et al. Use of complementary medicine by adult patients participating in HIV/AIDS clinical trials. J Altern Complement Med 2000; 6: 415–22PubMed
16.
Zurück zum Zitat Greene KB, Berger J, Reeves C, et al. Most frequently used alternative and complementary therapies and activities by participants in the AMCOA study. J Assoc Nurses AIDS Care 1999; 10: 60–73PubMed Greene KB, Berger J, Reeves C, et al. Most frequently used alternative and complementary therapies and activities by participants in the AMCOA study. J Assoc Nurses AIDS Care 1999; 10: 60–73PubMed
17.
Zurück zum Zitat Rosenfeld B, Breitbart W, Stein K, et al. Measuring desire for death among patients with HIV/AIDS: the schedule of attitudes toward hastened death. Am J Psychiatry 1999; 156: 94–100PubMed Rosenfeld B, Breitbart W, Stein K, et al. Measuring desire for death among patients with HIV/AIDS: the schedule of attitudes toward hastened death. Am J Psychiatry 1999; 156: 94–100PubMed
18.
Zurück zum Zitat Reilly CA, Holzmer WL, Henry SB, et al. A comparison of patient and nurse ratings of human immunodeficiency virus-related signs and symptoms. Nurs Res 1997; 46: 318–23PubMed Reilly CA, Holzmer WL, Henry SB, et al. A comparison of patient and nurse ratings of human immunodeficiency virus-related signs and symptoms. Nurs Res 1997; 46: 318–23PubMed
19.
Zurück zum Zitat Fantoni M, Ricci F, Del Borgo C, et al. Multicentre study on the prevalence of symptoms and symptomatic treatment in HIV infection. J Palliat Care 1997; 13: 9–13PubMed Fantoni M, Ricci F, Del Borgo C, et al. Multicentre study on the prevalence of symptoms and symptomatic treatment in HIV infection. J Palliat Care 1997; 13: 9–13PubMed
20.
Zurück zum Zitat Hewitt D, McDonald M, Portenoy R, et al. Pain syndromes and etiologies in ambulatory AIDS patients. Pain 1997; 70: 117–23PubMed Hewitt D, McDonald M, Portenoy R, et al. Pain syndromes and etiologies in ambulatory AIDS patients. Pain 1997; 70: 117–23PubMed
21.
Zurück zum Zitat Wesselmann U. Pain syndromes in AIDS. Anaesthesist 1996; 49: 1004–14 Wesselmann U. Pain syndromes in AIDS. Anaesthesist 1996; 49: 1004–14
22.
Zurück zum Zitat Holzemer WL, Henry SB, Reilly CA. Assessing and managing pain in AIDS care: the patient perspective. J Assoc Nurses AIDS Care 1998; 9: 22–30PubMed Holzemer WL, Henry SB, Reilly CA. Assessing and managing pain in AIDS care: the patient perspective. J Assoc Nurses AIDS Care 1998; 9: 22–30PubMed
23.
Zurück zum Zitat Schifitto G, McDermott MP, McArthur JC, et al. Incidence of and risk factors for HIV-associated distal sensory polyneuropathy. Neurology 2002; 58: 1764–8PubMed Schifitto G, McDermott MP, McArthur JC, et al. Incidence of and risk factors for HIV-associated distal sensory polyneuropathy. Neurology 2002; 58: 1764–8PubMed
24.
Zurück zum Zitat Breitbart W, McDonald MV, Rosenfeld B, et al. Fatigue in ambulatory AIDS patients. J Pain Symptom Manage 1998; 15: 159–67PubMed Breitbart W, McDonald MV, Rosenfeld B, et al. Fatigue in ambulatory AIDS patients. J Pain Symptom Manage 1998; 15: 159–67PubMed
25.
Zurück zum Zitat Fontaine A, Larue F, Lassauniere JM. Physicians’ recognition of the symptoms experienced by HIV patients: how reliable? J Pain Symptom Manage 1999; 18: 263–70PubMed Fontaine A, Larue F, Lassauniere JM. Physicians’ recognition of the symptoms experienced by HIV patients: how reliable? J Pain Symptom Manage 1999; 18: 263–70PubMed
26.
Zurück zum Zitat Vogl D, Rosenfeld B, Breitbart W, et al. Symptom prevalence, characteristics, and distress in AIDS outpatients. J Pain Symptom Manage 1999; 18: 253–62PubMed Vogl D, Rosenfeld B, Breitbart W, et al. Symptom prevalence, characteristics, and distress in AIDS outpatients. J Pain Symptom Manage 1999; 18: 253–62PubMed
27.
Zurück zum Zitat van Servellen G, Sarna L, Jablonski KJ. Women with HIV: living with symptoms. West J Nurs Res 1998; 20: 448–64PubMed van Servellen G, Sarna L, Jablonski KJ. Women with HIV: living with symptoms. West J Nurs Res 1998; 20: 448–64PubMed
28.
Zurück zum Zitat Ferrando S, Evans S, Goggin K, et al. Fatigue in HIV illness: relationship to depression, physical limitations, and disability. Psychosom Med 1998; 60: 759–64PubMed Ferrando S, Evans S, Goggin K, et al. Fatigue in HIV illness: relationship to depression, physical limitations, and disability. Psychosom Med 1998; 60: 759–64PubMed
29.
Zurück zum Zitat Rose LR, Pugh LC, Lears K, et al. The fatigue experience: persons with HIV infection. J Adv Nurs 1998; 28: 295–304PubMed Rose LR, Pugh LC, Lears K, et al. The fatigue experience: persons with HIV infection. J Adv Nurs 1998; 28: 295–304PubMed
30.
Zurück zum Zitat Ghani AC, Donnelly CA, Anderson RM. Patterns of antiretroviral use in the United States of America: analysis of three observational databases. HIV Med 2003; 4: 24–32PubMed Ghani AC, Donnelly CA, Anderson RM. Patterns of antiretroviral use in the United States of America: analysis of three observational databases. HIV Med 2003; 4: 24–32PubMed
31.
Zurück zum Zitat Newshan G, Bennett J, Holman S. Pain and other symptoms in ambulatory HIV patients in the age of highly active antiretroviral therapy. J Assoc Nurses AIDS Care 2002; 13: 78–83PubMed Newshan G, Bennett J, Holman S. Pain and other symptoms in ambulatory HIV patients in the age of highly active antiretroviral therapy. J Assoc Nurses AIDS Care 2002; 13: 78–83PubMed
32.
Zurück zum Zitat Corless IB, Bunch EH, Kemppainen JK, et al. Self-care for fatigue in patients with HIV. Oncol Nurs Forum 2002; 29: E60–9PubMed Corless IB, Bunch EH, Kemppainen JK, et al. Self-care for fatigue in patients with HIV. Oncol Nurs Forum 2002; 29: E60–9PubMed
33.
Zurück zum Zitat Doerfler RE. Sweetening the toxic cocktail: managing the side effects of HIV medications. Adv Nurse Pract 2002; 10: 52–103PubMed Doerfler RE. Sweetening the toxic cocktail: managing the side effects of HIV medications. Adv Nurse Pract 2002; 10: 52–103PubMed
34.
Zurück zum Zitat Murri R, Ammassari A, De Luca A, et al. Self-reported nonadherence with antiretroviral drugs predicts persistent condition. HIV Clin Trials 2001; 2: 323–9PubMed Murri R, Ammassari A, De Luca A, et al. Self-reported nonadherence with antiretroviral drugs predicts persistent condition. HIV Clin Trials 2001; 2: 323–9PubMed
35.
Zurück zum Zitat Ammassari A, Murri R, Pezzotti P, et al. Self-reported symptoms and medication side effects influence adherence to highly active antiretroviral therapy in persons with HIV infection. J Acquir Immune Defic Syndr 2001; 28: 445–9PubMed Ammassari A, Murri R, Pezzotti P, et al. Self-reported symptoms and medication side effects influence adherence to highly active antiretroviral therapy in persons with HIV infection. J Acquir Immune Defic Syndr 2001; 28: 445–9PubMed
36.
Zurück zum Zitat Reynolds NR, Neidig JL. Characteristics of nausea reported by HIV-infected patients initiating combination antiretroviral regimens. Clin Nurs Res 2002; 11: 71–88PubMed Reynolds NR, Neidig JL. Characteristics of nausea reported by HIV-infected patients initiating combination antiretroviral regimens. Clin Nurs Res 2002; 11: 71–88PubMed
37.
Zurück zum Zitat Vosvick M, Koopman C, Gore-Felton C, et al. Relationship of functional quality of life to strategies for coping with the stress of living with HIV/AIDS. Psychosomatics 2003; 44: 51–8PubMed Vosvick M, Koopman C, Gore-Felton C, et al. Relationship of functional quality of life to strategies for coping with the stress of living with HIV/AIDS. Psychosomatics 2003; 44: 51–8PubMed
38.
Zurück zum Zitat Sullivan AK, Burton CT, Nelson MR, et al. Restoration of human immunodeficiency virus-1-specific responses in patients changing from protease to non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy. Scand J Immunol 2003; 57: 600–7PubMed Sullivan AK, Burton CT, Nelson MR, et al. Restoration of human immunodeficiency virus-1-specific responses in patients changing from protease to non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy. Scand J Immunol 2003; 57: 600–7PubMed
39.
Zurück zum Zitat Millikin CP, Rourke SB, Halman MH, et al. Fatigue in HIV/AIDS is associated with depression and subjective neurocognitive complaints but not neuropsychological functioning. J Clin Exp Neuropsychol 2003; 25: 201–15PubMed Millikin CP, Rourke SB, Halman MH, et al. Fatigue in HIV/AIDS is associated with depression and subjective neurocognitive complaints but not neuropsychological functioning. J Clin Exp Neuropsychol 2003; 25: 201–15PubMed
40.
Zurück zum Zitat Galli M, Veglia F, Angarano G, et al. Gender differences in antiretroviral drug-related adipose tissue alterations: women are at higher risk than men and develop particular lipodystrophy patterns. J Acquir Immune Defic Syndr 2003; 34: 58–61PubMed Galli M, Veglia F, Angarano G, et al. Gender differences in antiretroviral drug-related adipose tissue alterations: women are at higher risk than men and develop particular lipodystrophy patterns. J Acquir Immune Defic Syndr 2003; 34: 58–61PubMed
41.
Zurück zum Zitat Power R, Tate HL, McGill SM, et al. A qualitative study of the psychosocial implications of lipodystrophy syndrome on HIV positive individuals. Sex Transm Infect 2003; 79: 137–41PubMed Power R, Tate HL, McGill SM, et al. A qualitative study of the psychosocial implications of lipodystrophy syndrome on HIV positive individuals. Sex Transm Infect 2003; 79: 137–41PubMed
42.
Zurück zum Zitat Collins E, Wagner C, Walmsley S. Psychosocial impact of the lipodystrophy syndrome in HIV infection. AIDS Read 2000; 10: 546–50PubMed Collins E, Wagner C, Walmsley S. Psychosocial impact of the lipodystrophy syndrome in HIV infection. AIDS Read 2000; 10: 546–50PubMed
43.
Zurück zum Zitat Craig T, Kakumanu S. Chronic fatigue syndrome: evaluation and treatment. Am Fam Physician 2002; 65: 1083–90PubMed Craig T, Kakumanu S. Chronic fatigue syndrome: evaluation and treatment. Am Fam Physician 2002; 65: 1083–90PubMed
44.
Zurück zum Zitat Monchamp T, Frishman WH. Exercise as a treatment modality for congestive heart failure. Heart Dis 2002; 4: 110–6PubMed Monchamp T, Frishman WH. Exercise as a treatment modality for congestive heart failure. Heart Dis 2002; 4: 110–6PubMed
45.
Zurück zum Zitat Mostert S, Kesselring J. Effects of a short-term exercise training program on aerobic fitness, fatigue, health perception, and activity level of subjects with multiple sclerosis. Mult Scler 2002; 8: 161–8PubMed Mostert S, Kesselring J. Effects of a short-term exercise training program on aerobic fitness, fatigue, health perception, and activity level of subjects with multiple sclerosis. Mult Scler 2002; 8: 161–8PubMed
46.
Zurück zum Zitat Mock V, Pickett M, Ropka ME, et al. Fatigue and quality of life outcomes of exercise during cancer treatment. Cancer Pract 2001; 9: 119–27PubMed Mock V, Pickett M, Ropka ME, et al. Fatigue and quality of life outcomes of exercise during cancer treatment. Cancer Pract 2001; 9: 119–27PubMed
47.
Zurück zum Zitat Ambrose K, Lyden AK, Clauw DJ. Applying exercise to the management of fibromyalgia. Curr Pain Headache Rep 2003; 7: 348–54PubMed Ambrose K, Lyden AK, Clauw DJ. Applying exercise to the management of fibromyalgia. Curr Pain Headache Rep 2003; 7: 348–54PubMed
48.
Zurück zum Zitat Oldervoll LM, Kaasa S, Knobel H, et al. Exercise reduces fatigue in chronic fatigued Hodgkins disease survivors: results from a pilot study. Eur J Cancer 2003; 39: 57–63PubMed Oldervoll LM, Kaasa S, Knobel H, et al. Exercise reduces fatigue in chronic fatigued Hodgkins disease survivors: results from a pilot study. Eur J Cancer 2003; 39: 57–63PubMed
49.
Zurück zum Zitat Monga U, Garber SL, Thornby J, et al. Role of exercise to prevent fatigue and improve quality of life in localized prostate cancer patients undergoing radiation therapy. Int J Radiat Oncol Biol Phys 2003; 57 (2 Suppl.): S445 Monga U, Garber SL, Thornby J, et al. Role of exercise to prevent fatigue and improve quality of life in localized prostate cancer patients undergoing radiation therapy. Int J Radiat Oncol Biol Phys 2003; 57 (2 Suppl.): S445
50.
Zurück zum Zitat Sarna L, Conde F. Physical activity and fatigue during radiation therapy: a pilot study using actigraph monitors. Oncol Nurs Forum 2001; 28: 1043–6PubMed Sarna L, Conde F. Physical activity and fatigue during radiation therapy: a pilot study using actigraph monitors. Oncol Nurs Forum 2001; 28: 1043–6PubMed
51.
Zurück zum Zitat Shwartz AL. Daily fatigue patterns and effect of exercise in women with breast cancer. Cancer Pract 2000; 8: 16–24 Shwartz AL. Daily fatigue patterns and effect of exercise in women with breast cancer. Cancer Pract 2000; 8: 16–24
52.
Zurück zum Zitat Courneya KS, Friedenreich CM. Physical exercise and quality of life following cancer diagnosis: a literature review. Ann Behav Med 1999; 21: 171–9PubMed Courneya KS, Friedenreich CM. Physical exercise and quality of life following cancer diagnosis: a literature review. Ann Behav Med 1999; 21: 171–9PubMed
53.
Zurück zum Zitat Mock V, Dow KH, Meares CJ, et al. Effects of exercise on fatigue, physical functioning, and emotional distress during radiation therapy for breast cancer. Oncol Nurs Forum 1997; 24: 991–1000PubMed Mock V, Dow KH, Meares CJ, et al. Effects of exercise on fatigue, physical functioning, and emotional distress during radiation therapy for breast cancer. Oncol Nurs Forum 1997; 24: 991–1000PubMed
54.
Zurück zum Zitat Oka RK, De Marco T, Haskell WL, et al. Impact of a home-based walking and resistance training program on quality of life in patients with heart failure. Am J Cardiol 2000; 85: 365–9PubMed Oka RK, De Marco T, Haskell WL, et al. Impact of a home-based walking and resistance training program on quality of life in patients with heart failure. Am J Cardiol 2000; 85: 365–9PubMed
55.
Zurück zum Zitat Morgan WP. Affective beneficence of vigorous physical activity. Med Sci Sports Exerc 1985; 17: 94–100PubMed Morgan WP. Affective beneficence of vigorous physical activity. Med Sci Sports Exerc 1985; 17: 94–100PubMed
56.
Zurück zum Zitat Thayer RE. Energy, tiredness, and tension effects of a sugar snack versus moderate exercise. J Pers Soc Psychol 1987; 52: 119–25PubMed Thayer RE. Energy, tiredness, and tension effects of a sugar snack versus moderate exercise. J Pers Soc Psychol 1987; 52: 119–25PubMed
57.
Zurück zum Zitat Gimenez M, Servera E, Vergara P, et al. Endurance training in patients with chronic obstructive pulmonary disease: a comparison of high versus moderate intensity. Arch Phys Med Rehabil 2000; 81: 102–9PubMed Gimenez M, Servera E, Vergara P, et al. Endurance training in patients with chronic obstructive pulmonary disease: a comparison of high versus moderate intensity. Arch Phys Med Rehabil 2000; 81: 102–9PubMed
58.
Zurück zum Zitat Rooyackers JM, Folgering HT. Cardio-respiratory load of exercise training in patients with severe COPD. Int J Rehabil Res 1998; 21: 259–71PubMed Rooyackers JM, Folgering HT. Cardio-respiratory load of exercise training in patients with severe COPD. Int J Rehabil Res 1998; 21: 259–71PubMed
59.
Zurück zum Zitat Alfaro V, Torras R, Prats MT, et al. Improvement in exercise tolerance and spirometric values in stable chronic obstructive pulmonary disease patients after an individualized outpatient rehabilitation programme. J Sports Med Phys Fitness 1996; 36: 195–203PubMed Alfaro V, Torras R, Prats MT, et al. Improvement in exercise tolerance and spirometric values in stable chronic obstructive pulmonary disease patients after an individualized outpatient rehabilitation programme. J Sports Med Phys Fitness 1996; 36: 195–203PubMed
60.
Zurück zum Zitat Celli BR. Current thoughts regarding treatment of chronic obstructive pulmonary disease. Med Clin North Am 1996; 80: 589–609PubMed Celli BR. Current thoughts regarding treatment of chronic obstructive pulmonary disease. Med Clin North Am 1996; 80: 589–609PubMed
61.
Zurück zum Zitat Janal MN, Colt EWD, Clark WC, et al. Pain sensitivity, mood and plasma endocrine levels in man following long-distance running: effects of naloxone. Pain 1984; 19: 13–25PubMed Janal MN, Colt EWD, Clark WC, et al. Pain sensitivity, mood and plasma endocrine levels in man following long-distance running: effects of naloxone. Pain 1984; 19: 13–25PubMed
62.
Zurück zum Zitat Droste C, Greenlee MW, Schreck M, et al. Experimental pain thresholds and plasma beta-endorphin levels during exercise. Med Sci Sports Exerc 1991; 23: 334–42PubMed Droste C, Greenlee MW, Schreck M, et al. Experimental pain thresholds and plasma beta-endorphin levels during exercise. Med Sci Sports Exerc 1991; 23: 334–42PubMed
63.
Zurück zum Zitat Bartholomew JB, Lewis BP, Linder DE, et al. Post-exercise analgesia: replication and extension. J Sports Sci 1996; 14: 329–34PubMed Bartholomew JB, Lewis BP, Linder DE, et al. Post-exercise analgesia: replication and extension. J Sports Sci 1996; 14: 329–34PubMed
64.
Zurück zum Zitat Koltyn KF, Arbogast RW. Perception of pain after resistance exercise. Br J Sports Med 1998; 32: 20–4PubMed Koltyn KF, Arbogast RW. Perception of pain after resistance exercise. Br J Sports Med 1998; 32: 20–4PubMed
65.
Zurück zum Zitat Koltyn KF. Exercise-induced hypoalgesia and intensity of exercise. Sports Med 2002; 32: 477–87PubMed Koltyn KF. Exercise-induced hypoalgesia and intensity of exercise. Sports Med 2002; 32: 477–87PubMed
66.
Zurück zum Zitat Busch A, Schachter CL, Peloso PM, et al. Exercise for treating fibromyalgia syndrome. Cochrane Database System Review 2002; (3): CD003786 Busch A, Schachter CL, Peloso PM, et al. Exercise for treating fibromyalgia syndrome. Cochrane Database System Review 2002; (3): CD003786
67.
Zurück zum Zitat Winningham ML, Mac Vicar MG. The effect of aerobic exercise on patient reports of nausea. Oncol Nurs Forum 1988; 15: 447–50PubMed Winningham ML, Mac Vicar MG. The effect of aerobic exercise on patient reports of nausea. Oncol Nurs Forum 1988; 15: 447–50PubMed
68.
Zurück zum Zitat Glace BW, Murphy CA, McHugh MP. Food intake and electrolyte status of ultramarathoners competing in extreme heat. J Am Coll Nutr 2002; 21: 553–9PubMed Glace BW, Murphy CA, McHugh MP. Food intake and electrolyte status of ultramarathoners competing in extreme heat. J Am Coll Nutr 2002; 21: 553–9PubMed
69.
Zurück zum Zitat Simren M. Physical Activity and the gastrointestinal tract. Eur J Gastroenterol Hepatol 2002; 14: 1053–6PubMed Simren M. Physical Activity and the gastrointestinal tract. Eur J Gastroenterol Hepatol 2002; 14: 1053–6PubMed
70.
Zurück zum Zitat Kugler J, Seelbach H, Kruskemper GM. Effects of rehabilitation exercise programmes on anxiety and depression in coronary patients: a meta-analysis. Br J Clin Psychol 1994; 33: 401–10PubMed Kugler J, Seelbach H, Kruskemper GM. Effects of rehabilitation exercise programmes on anxiety and depression in coronary patients: a meta-analysis. Br J Clin Psychol 1994; 33: 401–10PubMed
71.
Zurück zum Zitat Segar ML, Katch VL, Roth RS, et al. The effect of aerobic exercise on self-esteem and depressive and anxiety symptoms among breast cancer survivors. Oncol Nurs Forum 1998; 25: 107–12PubMed Segar ML, Katch VL, Roth RS, et al. The effect of aerobic exercise on self-esteem and depressive and anxiety symptoms among breast cancer survivors. Oncol Nurs Forum 1998; 25: 107–12PubMed
72.
Zurück zum Zitat Gowans SE, deHueck A, Abbey SE. Measuring exercise-induced mood changes in fibromyalgia: a comparison of several measures. Arthritis Rheum 2002; 47: 603–9PubMed Gowans SE, deHueck A, Abbey SE. Measuring exercise-induced mood changes in fibromyalgia: a comparison of several measures. Arthritis Rheum 2002; 47: 603–9PubMed
73.
Zurück zum Zitat Carney RM, McKevitt PM, Goldberg AP, et al. Psychological effects of exercise training in hemodialysis patients. Nephron 1983; 33: 179–81PubMed Carney RM, McKevitt PM, Goldberg AP, et al. Psychological effects of exercise training in hemodialysis patients. Nephron 1983; 33: 179–81PubMed
74.
Zurück zum Zitat Petajan JH, Gappmaier E, White AT, et al. Impact of aerobic training on fitness and quality of life in multiple sclerosis. Ann Neurol 1996; 39: 432–41PubMed Petajan JH, Gappmaier E, White AT, et al. Impact of aerobic training on fitness and quality of life in multiple sclerosis. Ann Neurol 1996; 39: 432–41PubMed
75.
Zurück zum Zitat Milani RV, Lavie CJ, Cassidy MM. Effects of cardiac rehabilitation and exercise training programs on depression in patients after major coronary events. Am Heart J 1996; 132: 726–32PubMed Milani RV, Lavie CJ, Cassidy MM. Effects of cardiac rehabilitation and exercise training programs on depression in patients after major coronary events. Am Heart J 1996; 132: 726–32PubMed
76.
Zurück zum Zitat Gowans SE, deHueck A, Voss S, et al. Effect of a randomized, controlled trial of exercise on mood and physical function in individuals with fibromyalgia. Arthritis Rheum 2001; 45: 519–29PubMed Gowans SE, deHueck A, Voss S, et al. Effect of a randomized, controlled trial of exercise on mood and physical function in individuals with fibromyalgia. Arthritis Rheum 2001; 45: 519–29PubMed
77.
Zurück zum Zitat Emery CF, Schein RL, Hauck ER, et al. Psychological and cognitive outcomes of a randomized trial of exercise among patients with chronic obstructive pulmonary disease. Health Psychol 1998; 17: 232–40PubMed Emery CF, Schein RL, Hauck ER, et al. Psychological and cognitive outcomes of a randomized trial of exercise among patients with chronic obstructive pulmonary disease. Health Psychol 1998; 17: 232–40PubMed
78.
Zurück zum Zitat Suh MR, Jung HH, Kim SB, et al. Effects of regular exercise on anxiety, depression, and quality of life in maintenance hemodialysis patients. Ren Fail 2002; 24: 337–45PubMed Suh MR, Jung HH, Kim SB, et al. Effects of regular exercise on anxiety, depression, and quality of life in maintenance hemodialysis patients. Ren Fail 2002; 24: 337–45PubMed
79.
Zurück zum Zitat Blanchard CM, Courneya KS, Laing D. Effects of acute exercise on state anxiety in breast cancer survivors. Oncol Nurs Forum 2001; 28: 1617–21PubMed Blanchard CM, Courneya KS, Laing D. Effects of acute exercise on state anxiety in breast cancer survivors. Oncol Nurs Forum 2001; 28: 1617–21PubMed
80.
Zurück zum Zitat Burnham TR, Wilcox A. Effects of exercise on physiological and psychological variables in cancer survivors. Med Sci Sports Exerc 2002; 34: 1863–7PubMed Burnham TR, Wilcox A. Effects of exercise on physiological and psychological variables in cancer survivors. Med Sci Sports Exerc 2002; 34: 1863–7PubMed
81.
Zurück zum Zitat Bartholomew JB, Miller BM. Affective responses to an aerobic dance class: the impact of perceived performance. Res Q Exerc Sport 2002; 73: 301–9PubMed Bartholomew JB, Miller BM. Affective responses to an aerobic dance class: the impact of perceived performance. Res Q Exerc Sport 2002; 73: 301–9PubMed
82.
Zurück zum Zitat Tuscon KM, Sinyor D. On the affective benefits of acute aerobic exercise: taking stock after twenty years of research. In: Sereganian P, editor. Exercise psychology: the influence of physical exercise on psychological processes. New York: John Wiley & Sons, 1993: 80–121 Tuscon KM, Sinyor D. On the affective benefits of acute aerobic exercise: taking stock after twenty years of research. In: Sereganian P, editor. Exercise psychology: the influence of physical exercise on psychological processes. New York: John Wiley & Sons, 1993: 80–121
83.
Zurück zum Zitat Hicks AL, Martin KA, Ditor DS, et al. Long-term exercise training in persons with spinal cord injury effects on strength, arm ergometry performance and psychological well-being. Spinal Cord 2003; 41: 34–43PubMed Hicks AL, Martin KA, Ditor DS, et al. Long-term exercise training in persons with spinal cord injury effects on strength, arm ergometry performance and psychological well-being. Spinal Cord 2003; 41: 34–43PubMed
84.
Zurück zum Zitat Rigsby LW, Dishman RK, Jackson AW, et al. Effects of exercise training on men seropositive for the human immunodeficiency virus-1. Med Sci Sports Exerc 1992; 24: 6–12PubMed Rigsby LW, Dishman RK, Jackson AW, et al. Effects of exercise training on men seropositive for the human immunodeficiency virus-1. Med Sci Sports Exerc 1992; 24: 6–12PubMed
85.
Zurück zum Zitat MacArthur RD, Levine SD, Birk TJ. Supervised exercise training improves cardiopulmonary fitness in HIV-infected persons. Med Sci Sports Exerc 1993; 25: 684–8PubMed MacArthur RD, Levine SD, Birk TJ. Supervised exercise training improves cardiopulmonary fitness in HIV-infected persons. Med Sci Sports Exerc 1993; 25: 684–8PubMed
86.
Zurück zum Zitat Stringer WW. HIV and aerobic exercise: current recommendations. Sports Med 1999; 28: 389–95PubMed Stringer WW. HIV and aerobic exercise: current recommendations. Sports Med 1999; 28: 389–95PubMed
87.
Zurück zum Zitat Stringer WW, Berezovskaya M, O’Brien WA, et al. The effect of exercise training on aerobic fitness, immune indicies, and quality of life in HIV+ patients. Med Sci Sports Exerc 1998; 30: 11–6PubMed Stringer WW, Berezovskaya M, O’Brien WA, et al. The effect of exercise training on aerobic fitness, immune indicies, and quality of life in HIV+ patients. Med Sci Sports Exerc 1998; 30: 11–6PubMed
88.
Zurück zum Zitat Perna F, LaPerriere A, Klimas N, et al. Cardiopulmonary and CD4 cell changes in response to exercise training in early symptomatic HIV infection. Med Sci Sports Exerc 1999; 31: 973–9PubMed Perna F, LaPerriere A, Klimas N, et al. Cardiopulmonary and CD4 cell changes in response to exercise training in early symptomatic HIV infection. Med Sci Sports Exerc 1999; 31: 973–9PubMed
89.
Zurück zum Zitat Smith BA, Neidig JL, Nickel JT, et al. Aerobic exercise: effects on parameters related to fatigue, dyspnea, weight and body composition in HIV-infected adults. AIDS 2001; 15: 693–701PubMed Smith BA, Neidig JL, Nickel JT, et al. Aerobic exercise: effects on parameters related to fatigue, dyspnea, weight and body composition in HIV-infected adults. AIDS 2001; 15: 693–701PubMed
90.
Zurück zum Zitat Grinspoon S, Corcoran C, Parlman K, et al. Effects of testosterone and progressive resistance training in eugonadal men with AIDS wasting: a randomized, controlled trial. Ann Intern Med 2000; 133: 348–55PubMed Grinspoon S, Corcoran C, Parlman K, et al. Effects of testosterone and progressive resistance training in eugonadal men with AIDS wasting: a randomized, controlled trial. Ann Intern Med 2000; 133: 348–55PubMed
91.
Zurück zum Zitat Fairfield WP, Finkelstein JS, Klibanski A, et al. Osteopenia in eugonadal men with acquired immune deficiency syndrome wasting syndrome. J Clin Endocrinol Metab 2001; 86: 2020–6PubMed Fairfield WP, Finkelstein JS, Klibanski A, et al. Osteopenia in eugonadal men with acquired immune deficiency syndrome wasting syndrome. J Clin Endocrinol Metab 2001; 86: 2020–6PubMed
92.
Zurück zum Zitat Fairfield WP, Treat M, Rosenthal DI, et al. Effects of testosterone and exercise on muscle leanness in eugonadal men with AIDS wasting. J Appl Physiol 2001; 90: 2166–71PubMed Fairfield WP, Treat M, Rosenthal DI, et al. Effects of testosterone and exercise on muscle leanness in eugonadal men with AIDS wasting. J Appl Physiol 2001; 90: 2166–71PubMed
93.
Zurück zum Zitat Wagner G, Rabkin J, Rabkin R. Exercise as a mediator of psychological and nutritional effects of testosterone therapy in HIV+ men. Med Sci Sports Exerc 1998; 30: 811–7PubMed Wagner G, Rabkin J, Rabkin R. Exercise as a mediator of psychological and nutritional effects of testosterone therapy in HIV+ men. Med Sci Sports Exerc 1998; 30: 811–7PubMed
94.
Zurück zum Zitat Bhasin S, Storer TW, Javanbakht M, et al. Testosterone replacement and resistance exercise in HIV-infected men with weight loss and low testosterone levels. JAMA 2000; 283: 763–70PubMed Bhasin S, Storer TW, Javanbakht M, et al. Testosterone replacement and resistance exercise in HIV-infected men with weight loss and low testosterone levels. JAMA 2000; 283: 763–70PubMed
95.
Zurück zum Zitat Yarasheski KE, Tebas P, Stanerson B, et al. Resistance exercise training reduces hypertriglyceridemia in HIV-infected men treated with antiviral therapy. J Appl Physiol 2001; 90: 133–8PubMed Yarasheski KE, Tebas P, Stanerson B, et al. Resistance exercise training reduces hypertriglyceridemia in HIV-infected men treated with antiviral therapy. J Appl Physiol 2001; 90: 133–8PubMed
96.
Zurück zum Zitat Roubenoff R, McDermott A, Weiss L, et al. Short-term progressive resistance training increases strength and lean body mass in adults infected with human immunodeficiency virus. AIDS 1999; 13: 231–9PubMed Roubenoff R, McDermott A, Weiss L, et al. Short-term progressive resistance training increases strength and lean body mass in adults infected with human immunodeficiency virus. AIDS 1999; 13: 231–9PubMed
97.
Zurück zum Zitat Roubenoff R. Acquired immunodeficiency syndrome wasting, functional performance, and quality of life. Am J Manag Care 2000; 6: 1003–16PubMed Roubenoff R. Acquired immunodeficiency syndrome wasting, functional performance, and quality of life. Am J Manag Care 2000; 6: 1003–16PubMed
98.
Zurück zum Zitat Roubenoff R, Wilson IB. Effect of resistance training on self reported physical functioning in HIV infection. Med Sci Sports Exerc 2001; 33: 1811–7PubMed Roubenoff R, Wilson IB. Effect of resistance training on self reported physical functioning in HIV infection. Med Sci Sports Exerc 2001; 33: 1811–7PubMed
99.
Zurück zum Zitat Agin D, Gallagher D, Wang J, et al. Effects of whey protein and resistance exercise on body cell mass, muscle strength, and quality of life in women with HIV. AIDS 2001; 15: 2431–40PubMed Agin D, Gallagher D, Wang J, et al. Effects of whey protein and resistance exercise on body cell mass, muscle strength, and quality of life in women with HIV. AIDS 2001; 15: 2431–40PubMed
100.
Zurück zum Zitat Agin D, Kotler DP, Papandreou D, et al. Effects of whey protein and resistance exercise on body composition and muscle strength in women with HIV infection. Ann N Y Acad Sci 2000; 904: 607–9PubMed Agin D, Kotler DP, Papandreou D, et al. Effects of whey protein and resistance exercise on body composition and muscle strength in women with HIV infection. Ann N Y Acad Sci 2000; 904: 607–9PubMed
101.
Zurück zum Zitat Yarasheski KE, Roubenoff R. Exercise treatment for HIV-associated metabolic and anthropomorphic complications. Exerc Sport Sci Rev 2001; 29: 170–4PubMed Yarasheski KE, Roubenoff R. Exercise treatment for HIV-associated metabolic and anthropomorphic complications. Exerc Sport Sci Rev 2001; 29: 170–4PubMed
102.
Zurück zum Zitat Jones SP, Doran DA, Leatt PB, et al. Short-term exercise training improves body composition and hyperlipidaemia in HIV-positive individuals with lipodystrophy. AIDS 2001; 15: 2049–51PubMed Jones SP, Doran DA, Leatt PB, et al. Short-term exercise training improves body composition and hyperlipidaemia in HIV-positive individuals with lipodystrophy. AIDS 2001; 15: 2049–51PubMed
103.
Zurück zum Zitat Thoni GJ, Fedou C, Brun JF, et al. Reduction of fat accumulation and lipid disorders by individualized light aerobic training in human immunodeficiency virus infected patients with lipodystrophy and/or dyslipidemia. Diabetes Metab 2002; 28: 397–404PubMed Thoni GJ, Fedou C, Brun JF, et al. Reduction of fat accumulation and lipid disorders by individualized light aerobic training in human immunodeficiency virus infected patients with lipodystrophy and/or dyslipidemia. Diabetes Metab 2002; 28: 397–404PubMed
104.
Zurück zum Zitat Roubenoff R, Weiss L, McDermott A, et al. A pilot study of exercise training to reduce trunk fat in adults with HIV-associated fat redistribution. AIDS 1999; 13: 1373–5PubMed Roubenoff R, Weiss L, McDermott A, et al. A pilot study of exercise training to reduce trunk fat in adults with HIV-associated fat redistribution. AIDS 1999; 13: 1373–5PubMed
105.
Zurück zum Zitat Mustafa T, Sy FS, Macera CA, et al. Association between exercise and HIV disease progression in a cohort of homosexual men. Ann Epidemiol 1999; 9: 127–31PubMed Mustafa T, Sy FS, Macera CA, et al. Association between exercise and HIV disease progression in a cohort of homosexual men. Ann Epidemiol 1999; 9: 127–31PubMed
106.
Zurück zum Zitat Neidig JL, Smith BA, Brashers DE. Aerobic exercise training for depressive symptom management in adults living with HIV infection. J Assoc Nurses AIDS Care 2003; 14: 30–40PubMed Neidig JL, Smith BA, Brashers DE. Aerobic exercise training for depressive symptom management in adults living with HIV infection. J Assoc Nurses AIDS Care 2003; 14: 30–40PubMed
107.
Zurück zum Zitat Terry L, Sprinz E, Ribeiro JP. Moderate and high intensity exercise training in HIV-1 seropositive individuals: a randomized trial. Int J Sports Med 1999; 20: 142–6PubMed Terry L, Sprinz E, Ribeiro JP. Moderate and high intensity exercise training in HIV-1 seropositive individuals: a randomized trial. Int J Sports Med 1999; 20: 142–6PubMed
108.
Zurück zum Zitat Lox CL, McAuley E, Tucker S. Physical training effects on acute exercise-induced feeling states in HIV-1 positive individuals. J Health Psychol 1996; 1: 235–40PubMed Lox CL, McAuley E, Tucker S. Physical training effects on acute exercise-induced feeling states in HIV-1 positive individuals. J Health Psychol 1996; 1: 235–40PubMed
109.
Zurück zum Zitat Lox CL, McAuley E, Tucker S. Exercise as an intervention for enhancing subjective well-being in an HIV-1 population. J Sport Exerc Psychol 1995; 17: 345–62 Lox CL, McAuley E, Tucker S. Exercise as an intervention for enhancing subjective well-being in an HIV-1 population. J Sport Exerc Psychol 1995; 17: 345–62
110.
Zurück zum Zitat Schlenzig C, Jager H, Rieder H. Supervised physical exercise leads to psychological and immunological improvement in pre-AIDS patients. Preceedings of the 5th International AIDS Conference; 1989 Jun 4–9; Montreal, 337 Schlenzig C, Jager H, Rieder H. Supervised physical exercise leads to psychological and immunological improvement in pre-AIDS patients. Preceedings of the 5th International AIDS Conference; 1989 Jun 4–9; Montreal, 337
111.
Zurück zum Zitat Nicholas PK, Kemppainen JK, Holzerner WL, et al. Self-care management for neuropathy in HIV disease. AIDS Care 2002; 14: 763–71PubMed Nicholas PK, Kemppainen JK, Holzerner WL, et al. Self-care management for neuropathy in HIV disease. AIDS Care 2002; 14: 763–71PubMed
112.
Zurück zum Zitat LaPerriere AR, Antoni MH, Schneiderman N, et al. Exercise intervention attenuates emotional distress and natural killer cell decrements following notification of positive serologic status for HIV-1. Biofeedback Self Regul 1990; 15: 229–42PubMed LaPerriere AR, Antoni MH, Schneiderman N, et al. Exercise intervention attenuates emotional distress and natural killer cell decrements following notification of positive serologic status for HIV-1. Biofeedback Self Regul 1990; 15: 229–42PubMed
113.
Zurück zum Zitat Rejeski WJ, Gauvin L, Hobson ML, et al. Effects of baseline responses, in-task feelings, and duration of activity on exercise-induced feeling states in women. Health Psychol 1995; 14: 350–9PubMed Rejeski WJ, Gauvin L, Hobson ML, et al. Effects of baseline responses, in-task feelings, and duration of activity on exercise-induced feeling states in women. Health Psychol 1995; 14: 350–9PubMed
114.
Zurück zum Zitat Bopp CM, Phillips KD, Fulk LJ, et al. Clinical implications of therapeutic exercise in HIV/AIDS. J Assoc Nurses AIDS Care 2003; 14: 73–8PubMed Bopp CM, Phillips KD, Fulk LJ, et al. Clinical implications of therapeutic exercise in HIV/AIDS. J Assoc Nurses AIDS Care 2003; 14: 73–8PubMed
115.
Zurück zum Zitat Malina RM. Adherence to physical activity from childhood to adulthood: a perspective from tracking studies. Quest 2001; 53: 346–55 Malina RM. Adherence to physical activity from childhood to adulthood: a perspective from tracking studies. Quest 2001; 53: 346–55
Metadaten
Titel
The Benefits of Exercise Training for Quality of Life in HIV/AIDS in the Post-HAART Era
verfasst von
Joseph T. Ciccolo
Esbelle M. Jowers
John B. Bartholomew
Publikationsdatum
01.07.2004
Verlag
Springer International Publishing
Erschienen in
Sports Medicine / Ausgabe 8/2004
Print ISSN: 0112-1642
Elektronische ISSN: 1179-2035
DOI
https://doi.org/10.2165/00007256-200434080-00001

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