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01.01.2008 | Cardiac

Magnetic resonance coronary angiography with vasovist™: in-vivo T ₁ estimation to improve image quality of navigator and breath-hold techniques

verfasst von: Kai Nassenstein, Kai-Uwe Waltering, Sebastian Kelle, Thomas Schlosser, Frank Breuckmann, Stefan Maderwald, Peter Hunold, Eike Nagel, Jörg Barkhausen

Erschienen in: European Radiology | Ausgabe 1/2008

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Abstract

The purpose of the study was to estimate T ₁ values of blood and myocardium after a single injection of Vasovist™ and to assess Vasovist™ for magnetic resonance coronary angiography (MRCA). For all exams 0.05 mmol/kg of Vasovist™ was injected. T ₁ values of blood and myocardium were estimated over 30 min after injection. Twelve volunteers were examined on a 1.5-T Siemens system using a SSFP sequence with incrementally increasing inversion times for T ₁-estimation and a breath-hold 3D IR-FLASH sequence for MRCA. Eleven examinations were performed on 1.5-T Philips system using the Look-Locker approach for T ₁ estimation and a whole-heart inversion-prepared, 3D SSFP sequence for MRCA. SNR, CNR and image quality were assessed. T ₁ values of blood (5 min: 230 ms vs. 30 min: 275 ms) and myocardium (5 min: 99 ms vs. 30 min: 130 ms) increased over time. Whereas the blood SNR (1 min: 23.6 vs. 30 min: 21.2) showed no significant differences, the blood-to-myocardium CNR (1 min: 18.1 vs. 30 min: 13.8) and the image quality (1 min: 2.9 vs. 30 min: 3.8) degraded over time. Due to long plasma half-time the T1-shortening effect of Vasovist™ remains effective over 30 min, which allows for multiple breath-hold or high-resolution MRCA.

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Titel: Magnetic resonance coronary angiography with vasovist™: in-vivo T 1 estimation to improve image quality of navigator and breath-hold techniques
verfasst von: Kai Nassenstein
Kai-Uwe Waltering
Sebastian Kelle
Thomas Schlosser
Frank Breuckmann
Stefan Maderwald
Peter Hunold
Eike Nagel
Jörg Barkhausen
Publikationsdatum: 01.01.2008
Verlag: Springer-Verlag
Erschienen in: European Radiology / Ausgabe 1/2008
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-007-0720-0

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Magnetic resonance coronary angiography with vasovist™: in-vivo T ₁ estimation to improve image quality of navigator and breath-hold techniques

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