Erschienen in:
01.04.2003 | Clinical Investigation
Malignant Esophagogastric Junction Obstruction: Efficacy of
Balloon Dilation Combined with Chemotherapy and/or Radiation Therapy
verfasst von:
Gi-Young Ko, Ho-Young Song, Heuk-Jin Hong, Kyu-Bo Sung, Tae-Seok Seo, Hyun-Ki Yoon
Erschienen in:
CardioVascular and Interventional Radiology
|
Ausgabe 2/2003
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Abstract
Purpose: To assess the efficacy of
balloon dilation combined with chemotherapy and/or radiation therapy
for palliation of dysphagia due to malignant esophagogastric junction
strictures.
Methods: Fluoroscopically guided balloon
dilation was attempted in 20 patients. The causes of strictures were
gastric adenocarcinoma (n = 10) and esophageal squamous
cell carcinoma (n = 10). Scheduled chemotherapy and/or
radiation therapy followed balloon dilation in all patients.
Results: There were no technical failures or major
complications. After balloon dilation, 15 (75%) patients showed
improvement of dysphagia. No patient complained of reflux esophagitis
during the follow-up period. Among the 15 patients, seven needed no
further treatment for palliation of dysphagia until their deaths. The
remaining eight patients underwent repeat balloon dilation
(n = 4) or stent placement (n = 4)
3–43 weeks (mean 15 weeks) after the initial balloon dilation because
of recurrent dysphagia.
Conclusion: Balloon dilation
combined with chemotherapy and/or radiation therapy seems to be an easy
and reasonably effective palliative treatment for malignant
esophagogastric strictures.