The relationship between maternal body compositions and birth weight was not definite. Fat Mass (FM) and Fat Free Mass (FFM) can accurately reflect the maternal body fat compositions and have been considered as better predictors of birth weight. Despite its potential role, no studies have been described the maternal compositions during pregnancy in East Asian women previously. We investigated the correlation between birth weight and Maternal body composition including fat mass (FM) and fat free mass (FFM). To determine whether birth weight is associated with maternal body fat FM and FFM during pregnancy and, if so, which trimester and parameter is more critical in determining birth weight.
A longitudinal prospective observational study performed, 348, 481 and 321 non-diabetics Han Chinese women with a singleton live birth attending a routine visit in their first, second and third trimesters were recruited. Maternal body composition was measured using segmental multi-frequency bioelectrical impedance analysis. Data of the pre-pregnancy body mass index (BMI), maternal BMI, the gestational weight gain (GWG), and placental and birth weight were collected.
A significant correlation exists between maternal FFM in the process of pregnancy, placental weight, GWG at delivery, and birth weight (P < 0.05). On stepwise multiple linear regression analysis, material’s FFM was the most important factor associated with the birth weight. After adjustment, there was significantly associated with 2.47-fold increase in risk for birth weight more than 4 kg when FFM ≥ 40.76 kg (Upper quartile of participants). The increased maternal age became a protective factor (OR = 0.69) while the increased pre-pregnancy BMI (OR = 1.50) remained predictors to birth weight more than 4 kg.
The change of maternal FFM during pregnancy is independently affected the birth weight.
Dietz PM, Kuklina EV, Bateman BT, Callaghan WM. Assessing cardiovascular disease risk among young women with a history of delivering a low-birth-weight infant. Am J Perinatol. 2013;30:267–73. PubMed
Grandi C, Tapia JL, Marshall G. An assessment of the severity, proportionality and risk of mortality of very low birth weight infants with fetal growth restriction. A multicenter South American analysis. J Pediatr (Rio J). 2005;81:198–204. CrossRef
Cheng YK, Lao TT, Sahota DS, Leung VK, Leung TY. Use of birth weight threshold for macrosomia to identify fetuses at risk of shoulder dystocia among Chinese populations. Int J GynaecolObstet. 2013;120:249–53.
Scholl TO, Hediger ML, Khoo CS, Healey MF, Rawson NL. Maternal weight gain, diet and infant birth weight: correlations during adolescent pregnancy. J ClinEpidemiol. 1991;44:423–8.
Widen EM, Gallagher D. Body composition changes in pregnancy: measurement, predictors and outcomes. Eur J ClinNutr. 2014;68:643–52. CrossRef
Sanin AL, Reza-Lopez S, Levario-Carrillo M. Relation between maternal body composition and birth weight. Biol Neonate. 2004;86:55–62. CrossRef
Kulkarni B, Shatrugna V, Balakrishna N. Maternal lean body mass may be the major determinant of birth weight: A study from India. Eur J ClinNutr. 2006;60:1341–4. CrossRef
Kent E, O’Dwyer V, Fattah C, Farah N, O’Connor C, Turner MJ. Correlation between birth weight and maternal body composition. ObstetGynecol. 2013;121:46–50.
Azuma K, Curb JD, Kadowaki T, Edmundowicz D, Kadowaki S, Masaki KH, et al. Ethnic difference in liver fat content: a cross-sectional observation among Japanese American in Hawaii, Japanese in Japan, and non-Hispanic whites in United States. Obes Res ClinPract. 2013;7:e198–205. CrossRef
Albrecht SS, Diez RA, Kandula NR, Osypuk TL, Ni H, Shrager S. Immigrant assimilation and BMI and waist size: a longitudinal examination among Hispanic and Chinese participants in the multi-ethnic study of atherosclerosis. Obesity (Silver Spring). 2013;21:1695–703. CrossRef
- Maternal fat free mass during pregnancy is associated with birth weight
- BioMed Central
Neu im Fachgebiet Gynäkologie und Geburtshilfe
Meistgelesene Bücher aus dem Fachgebiet
Mail Icon II