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Endocrine Pathology

Erschienen in:

10.05.2017

MEN2 Syndrome-Related Medullary Thyroid Carcinoma with Focal Tyrosine Hydroxylase Expression: Does It Represent a Hybrid Cellular Phenotype or Functional State of Tumor Cells?

verfasst von: Ozgur Mete, Ahmed Essa, Anil Bramdev, Navendren Govender, Runjan Chetty

Erschienen in: Endocrine Pathology | Ausgabe 4/2017

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Excerpt

A 38-year-old woman presented with abdominal pain, right-sided large thyroid mass with dysphagia, lower backache, and weight gain. During the clinical examination, she was pale and was found to have hypertension. The initial laboratory testing showed a normal thyroid function along with low hemoglobin (7.6 g/dl, normal: 12–15 g/dl). Ultrasound identified a large thyroid mass occupying almost the entire right lobe. No cervical lymphadenopathy was detected. A fine needle-aspiration biopsy of the thyroid mass was scheduled; however, the patient opted for total thyroidectomy given her elevated calcitonin (19930 ng/l; normal: 0–5 ng/l) and CEA (1425 ng/ml; normal: 0–5 ng/ml) levels. …

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Zabel M, Grzeszkowiak J. Characterisation of thyroid medullary carcinoma TT cell line. Histol Histopathol.12:283–289, 1997.PubMed

Titel: MEN2 Syndrome-Related Medullary Thyroid Carcinoma with Focal Tyrosine Hydroxylase Expression: Does It Represent a Hybrid Cellular Phenotype or Functional State of Tumor Cells?
verfasst von: Ozgur Mete
Ahmed Essa
Anil Bramdev
Navendren Govender
Runjan Chetty
Publikationsdatum: 10.05.2017
Verlag: Springer US
Erschienen in: Endocrine Pathology / Ausgabe 4/2017
Print ISSN: 1046-3976
Elektronische ISSN: 1559-0097
DOI: https://doi.org/10.1007/s12022-017-9485-4

Springer Medizin

MEN2 Syndrome-Related Medullary Thyroid Carcinoma with Focal Tyrosine Hydroxylase Expression: Does It Represent a Hybrid Cellular Phenotype or Functional State of Tumor Cells?

Excerpt

Neu im Fachgebiet Pathologie

Molekularpathologische Untersuchungen im Wandel der Zeit

Vergleichende Pathologie in der onkologischen Forschung

Gastrointestinale Stromatumoren

Personalisierte Medizin in der Onkologie

Springer Medizin

Excerpt

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