Background
Methods
Characteristics | Patients with SIA (n = 199) | Controls (n = 194) | P | OR (95% CI) |
---|---|---|---|---|
age range and mean age | 14-73 (43.2) | 18-59 (38.4) | >0.05 | |
males | 96 (48.2%) | 86 (44.3%) | >0.05 | |
patients with arterial hypertension | 115 (57.8%) | 18 (9.3%) | <0.0001 | 13.4 (7.6-23.4) |
patients with systemic CTD | 125 (62.8%) | 23 (11.8%) | <0.0001 | 12,5 (7,45-21,1) |
patients who have relatives with stroke | 50 (25.1%) | 20 (10.3%) | <0.0001 | 2.9 (1.7-5.1) |
patients who have relatives with SIA | 10 (5.0%) | 0 | ||
patients who have relatives with headaches | 114 (57.3%) | 46 (23.7%) | <0.0001 | 4.3 (2.8-6.6) |
smokers | 102 (51.2%) | 102 (52.6%) | >0.05 | |
patients with alcohol consumption | 69 (34.7%) | 77 (39.7%) | >0.05 | |
patients with increased BMI (>25) | 148 (74.4%) | 112 (57.7%) | >0.05 | |
patients with headaches | 124 (62.3%) | 63 (32.5%) | <0.0001 | 3.4 (2.3 -5.2) |
patients who used analgetics more than 15 times per month | 9 (4.5%) | 3 (1.5%) | >0.05 |
Statistical analysis
Results
Types of headaches | Patients with SIA (n = 199) | Controls (n = 194) | P | OR | 95% CI |
---|---|---|---|---|---|
Migraine without aura (MO) | 78 (39.2%) | 17 (8.8%) | <0.0001 | 6.7 | 3.8 -11.9 |
Migraine with aura (MA) | 2 (1%) | 0 | >0.05 | ||
Probable migraine (PM) | 4 (2%) | 0 | >0.05 | ||
Tension type headache (TTH) | 39 (19.6%) | 45 (23.1%) | >0.05 | ||
Cluster headache (CH) | 2 (1%) | 0 | >0.05 | ||
Posttraumatic headaches (PH) | 2 (1%) | 1 (0.5%) | >0.05 |
Side of SIA/Side of headache | Localization of SIA | |||
---|---|---|---|---|
AcoA-ACA (n = 18) | MCA (n = 16) | ICA (n = 23) | Posterior circulation (n = 6) | |
right/right | 1 (6.2%) | 4 (17.4%) | 1 (16.6%) | |
left/left | 3 (16.6%) | 1 (6.2%) | 4 (17.4%) | |
left/right | 1 (5.5%) | 1 (4.3%) | ||
right/alternating sides | 8 (44.4%) | 8 (50%) | 7 (30.4%) | |
left/alternating sides | 6 (33.3%) | 6 (37.5%) | 7 (30.4%) | 3 (50%) |
Basilar artery/alternating sides | 2 (33.3%) |
Localization of migraine | Localization of SIA | ||||
---|---|---|---|---|---|
AcoA-ACA (n = 18) | MCA (n = 16) | ICA (n = 23) | Posterior circulation (n = 6) | Multiple SIA (n = 17) | |
Always same localization of migraine headache
| |||||
Patient uncertain | 1 (6.2%) | 2 (8.7%) | 1 (5.8%) | ||
Temporal | 2 (11.1%) | 3 (18.7%) | 6 (26.1%) | 2 (33.3%) | 3 (17.6%) |
Fronto-temporal | 13 (72.2%) | 4 (25%) | 5 (21.7%) | 5 (29.4%) | |
Occipital | 1 (6.2%) | 1 (4.3) | |||
Parietal | 1 (5.8%) | ||||
Variable localization of migraine headache
| |||||
Temporal + parietal | 1 (16.6%) | 2 (11.7%) | |||
Fronto-temporal + occipital | 1 (5.5%) | 2 (12.5%) | 1 (5.8%) | ||
Fronto-temporal + half-side | 1 (6.2%) | 1 (4.3%) | |||
Fronto-temporal + parietal | 1 (6.2%) | 2 (8.7%) | 2 (11.7%) | ||
Fronto-temporal + Parietal + occipital | 1 (5.5.%) | 1 (4.3%) | |||
Temporal + parietal + occipital + half-side | 1 (4.3%) | 2 (33.3%) | |||
Temporal + occipital | 4 (17.4%) | 1 (16.6%) | 1 (5.8%) | ||
Temporal + occipital + half-side | 1 (5.5%) | 1 (5.8%) | |||
Parietal + occipital | 1 (6.2%) | ||||
Parietal + occipital + half-side | 1 (6.2%) | ||||
Parietal + half-side | 1 (6.2%) |
Factors | Patients with migraine (n = 80) | Patients without migraine (n = 119) | P | OR | 95% CI |
---|---|---|---|---|---|
mean age | 42.7 | 43.8 | |||
Male | 20 (25%) | 76 (63.9%) | <0.0001 | 0.19 | 0.10-0.35 |
Female | 60 (75%) | 43 (36.1%) | <0.0001 | 5.3 | 2.8-9.9 |
Smoking | 32 (40%) | 69 (57.9%) | 0.01 | 0.48 | 0.27-0.86 |
Male | 18 (22.5%) | 63 (52.9%) | <0.0001 | 0.26 | 0.14-0.49 |
Female | 14 (17.5%) | 6 (5.0%) | 0.004 | 3.99 | 1.5 – 10.9 |
AH | 55 (68.7%) | 59 (49.6%) | 0.007 | 2.2 | 1.2-4.0 |
multiple SIA | 17 (21.2%) | 19 (15.9%) | 0.34 | ||
large SIA (11-25 mm) | 4 (5%) | 7 (5.8%) | 0.78 | ||
giant SIA (>25 mm) | 6 (7.5%) | 5 (4.2%) | 0.32 | ||
normal size SIA (5-10 mm) | 66 (82.5%) | 98 (82.3%) | 0.97 | ||
small SIA (<5 mm) | 4 (5%) | 9 (7.6%) | 0.47 | ||
stroke in relatives | 24 (30%) | 26 (21.8%) | 0.19 | ||
SIA in relatives | 5 (6.2%) | 5 (4.2%) | 0.51 | ||
Headaches in relatives | 55 (68.7%) | 59 (49.6%) | 0.007 | 2.2 | 1.2-4.0 |
systemic CTD | 51 (63.7%) | 73 (61.3%) | 0.73 | ||
BMI >25 | 46 (57.5%) | 66 (55.5%) | 0.77 | ||
BMI <25 | 34 (42.5%) | 53 (44.5%) | 0.77 | ||
Localization of SIA | |||||
ACoA-ACA | 19 (23.7%) | 55 (46.2%) | 0.001 | 0.36 | 0.19-0.68 |
MCA | 22 (27.5%) | 28 (23.5%) | 0.52 | ||
ICA (+PCoA) | 31 (38.7%) | 32 (26.9%) | 0.08 | ||
posterior circulation (vertebral, basilar, PICA) | 8 (10%) | 4 (3.4%) | 0.05 | 3.19 | 0.93-10.9 |
right | 40 (50%) | 56 (47.1%) | 0.68 | ||
left | 38 (47.5%) | 61 (51.2%) | 0.60 | ||
Basilar | 2 (2.5%) | 2 (1.7%) | 0.68 |