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23.02.2018 | Neuro

Monitoring cerebral blood flow change through use of arterial spin labelling in acute ischaemic stroke patients after intra-arterial thrombectomy

verfasst von: Roh-Eul Yoo, Tae Jin Yun, Dong Hyun Yoo, Young Dae Cho, Hyun-Seung Kang, Byung-Woo Yoon, Keun-Hwa Jung, Koung Mi Kang, Seung Hong Choi, Ji-hoon Kim, Chul-Ho Sohn

Erschienen in: European Radiology | Ausgabe 8/2018

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Abstract

Objectives

To evaluate the ability of arterial spin labelling perfusion-weighted imaging (ASL-PWI) to identify reperfusion status and to predict the early neurological outcome of acute ischaemic stroke patients after intra-arterial (IA) thrombectomy.

Methods

A total of 51 acute ischaemic stroke patients who underwent IA thrombectomy were retrospectively reviewed. Asymmetrical index before and after IA thrombectomy (AICBF_pre and AICBF_post) and volume ratio of the reperfused territory to the baseline perfusion abnormality (reperfusion volume ratio) were calculated on ASL-PWI. A paired t-test was used to compare AICBF_pre and AICBF_post. Pearson correlation and multiple linear regression were performed to evaluate correlations between the imaging parameters and NIHSS scores.

Results

Mean AICBF_post was significantly higher than mean AICBF_pre (0.923±0.352 vs. 0.312±0.191, p<0.001). AICBF_pre had a significant correlation with NIHSS_pre (pr=–0.430, p=.004). ∆AICBF had significant correlations with NIHSS_{24 h}, NIHSS_{5-7 days} and ∆NIHSS_{5-7 days} (r=–0.356, p=0.028; r=–0.597, p<0.001; r=–0.346, p=0.033, respectively). ∆AICBF, reperfusion volume ratio and baseline infarct volume were significant independent predictors for NIHSS_{5-7 days}.

Conclusions

ASL-PWI has the potential to serve as a non-invasive imaging tool to monitor the reperfusion status and predict the early neurological outcome of acute ischaemic stroke patients after IA thrombectomy.

Key Points

• CBF change on ASL-PWI after IA thrombectomy correlated with NIHSS scores.

• ASL-PWI can non-invasively monitor reperfusion in AIS patients after IA thrombectomy.

• ASL-PWI may predict early outcome of AIS patients after IA thrombectomy.

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Titel: Monitoring cerebral blood flow change through use of arterial spin labelling in acute ischaemic stroke patients after intra-arterial thrombectomy
verfasst von: Roh-Eul Yoo
Tae Jin Yun
Dong Hyun Yoo
Young Dae Cho
Hyun-Seung Kang
Byung-Woo Yoon
Keun-Hwa Jung
Koung Mi Kang
Seung Hong Choi
Ji-hoon Kim
Chul-Ho Sohn
Publikationsdatum: 23.02.2018
Verlag: Springer Berlin Heidelberg
Erschienen in: European Radiology / Ausgabe 8/2018
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-018-5319-0

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Monitoring cerebral blood flow change through use of arterial spin labelling in acute ischaemic stroke patients after intra-arterial thrombectomy