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Erschienen in: Abdominal Radiology 11/2019

30.04.2019 | Special Section: Rectal Cancer

MR staging of anal cancer: what the radiologist needs to know

verfasst von: Jennifer S. Golia Pernicka, Shannon P. Sheedy, Randy D. Ernst, Bruce D. Minsky, Dhakshinamoorthy Ganeshan, Gaiane M. Rauch

Erschienen in: Abdominal Radiology | Ausgabe 11/2019

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Abstract

Anal canal cancer is a rare disease and squamous cell carcinoma is the most common histologic subtype. Traditionally, anal cancer is imaged with CT and PET/CT for purposes of TNM staging. With the increased popularity of MRI for rectal cancer evaluation, MRI has become increasingly utilized for local staging of anal cancer. In this review, we focus on the necessary information radiologists need to know to understand this rare and unique disease and to be familiar with staging of anal cancer on MRI.
Literatur
3.
Zurück zum Zitat Nigro ND, Vaitkevicius VK, Considine B, Jr. (1974) Combined therapy for cancer of the anal canal: a preliminary report. Dis Colon Rectum 17 (3):354-356 Nigro ND, Vaitkevicius VK, Considine B, Jr. (1974) Combined therapy for cancer of the anal canal: a preliminary report. Dis Colon Rectum 17 (3):354-356
8.
Zurück zum Zitat Chiu S, Joseph K, Ghosh S, Cornand RM, Schiller D (2015) Reasons for delays in diagnosis of anal cancer and the effect on patient satisfaction. Canadian family physician Medecin de famille canadien 61 (11):e509-516 Chiu S, Joseph K, Ghosh S, Cornand RM, Schiller D (2015) Reasons for delays in diagnosis of anal cancer and the effect on patient satisfaction. Canadian family physician Medecin de famille canadien 61 (11):e509-516
9.
Zurück zum Zitat Morris VK, Rashid A, Rodriguez-Bigas M, Das P, Chang G, Ohinata A, Rogers J, Crane C, Wolff RA, Eng C (2015) Clinicopathologic Features Associated With Human Papillomavirus/p16 in Patients With Metastatic Squamous Cell Carcinoma of the Anal Canal. The oncologist 20 (11):1247-1252. https://doi.org/10.1634/theoncologist.2015-0091 Morris VK, Rashid A, Rodriguez-Bigas M, Das P, Chang G, Ohinata A, Rogers J, Crane C, Wolff RA, Eng C (2015) Clinicopathologic Features Associated With Human Papillomavirus/p16 in Patients With Metastatic Squamous Cell Carcinoma of the Anal Canal. The oncologist 20 (11):1247-1252. https://​doi.​org/​10.​1634/​theoncologist.​2015-0091
10.
Zurück zum Zitat Darragh TM, Colgan TJ, Thomas Cox J, Heller DS, Henry MR, Luff RD, McCalmont T, Nayar R, Palefsky JM, Stoler MH, Wilkinson EJ, Zaino RJ, Wilbur DC (2013) The Lower Anogenital Squamous Terminology Standardization project for HPV-associated lesions: background and consensus recommendations from the College of American Pathologists and the American Society for Colposcopy and Cervical Pathology. International journal of gynecological pathology: official journal of the International Society of Gynecological Pathologists 32 (1):76-115. https://doi.org/10.1097/pgp.0b013e31826916c7 Darragh TM, Colgan TJ, Thomas Cox J, Heller DS, Henry MR, Luff RD, McCalmont T, Nayar R, Palefsky JM, Stoler MH, Wilkinson EJ, Zaino RJ, Wilbur DC (2013) The Lower Anogenital Squamous Terminology Standardization project for HPV-associated lesions: background and consensus recommendations from the College of American Pathologists and the American Society for Colposcopy and Cervical Pathology. International journal of gynecological pathology: official journal of the International Society of Gynecological Pathologists 32 (1):76-115. https://​doi.​org/​10.​1097/​pgp.​0b013e31826916c7​
18.
Zurück zum Zitat Beets-Tan RGH, Lambregts DMJ, Maas M, Bipat S, Barbaro B, Curvo-Semedo L, Fenlon HM, Gollub MJ, Gourtsoyianni S, Halligan S, Hoeffel C, Kim SH, Laghi A, Maier A, Rafaelsen SR, Stoker J, Taylor SA, Torkzad MR, Blomqvist L (2018) Magnetic resonance imaging for clinical management of rectal cancer: Updated recommendations from the 2016 European Society of Gastrointestinal and Abdominal Radiology (ESGAR) consensus meeting. European radiology 28 (4):1465-1475. https://doi.org/10.1007/s00330-017-5026-2 Beets-Tan RGH, Lambregts DMJ, Maas M, Bipat S, Barbaro B, Curvo-Semedo L, Fenlon HM, Gollub MJ, Gourtsoyianni S, Halligan S, Hoeffel C, Kim SH, Laghi A, Maier A, Rafaelsen SR, Stoker J, Taylor SA, Torkzad MR, Blomqvist L (2018) Magnetic resonance imaging for clinical management of rectal cancer: Updated recommendations from the 2016 European Society of Gastrointestinal and Abdominal Radiology (ESGAR) consensus meeting. European radiology 28 (4):1465-1475. https://​doi.​org/​10.​1007/​s00330-017-5026-2
19.
Zurück zum Zitat Kaur H, Choi H, You YN, Rauch GM, Jensen CT, Hou P, Chang GJ, Skibber JM, Ernst RD (2012) MR imaging for preoperative evaluation of primary rectal cancer: practical considerations. Radiographics: a review publication of the Radiological Society of North America, Inc 32 (2):389-409. https://doi.org/10.1148/rg.322115122 Kaur H, Choi H, You YN, Rauch GM, Jensen CT, Hou P, Chang GJ, Skibber JM, Ernst RD (2012) MR imaging for preoperative evaluation of primary rectal cancer: practical considerations. Radiographics: a review publication of the Radiological Society of North America, Inc 32 (2):389-409. https://​doi.​org/​10.​1148/​rg.​322115122
20.
Zurück zum Zitat Nougaret S, Rouanet P, Molinari N, Pierredon MA, Bibeau F, Azria D, Lemanski C, Assenat E, Duffour J, Ychou M, Reinhold C, Gallix B (2012) MR volumetric measurement of low rectal cancer helps predict tumor response and outcome after combined chemotherapy and radiation therapy. Radiology 263 (2):409-418. https://doi.org/10.1148/radiol.12111263 Nougaret S, Rouanet P, Molinari N, Pierredon MA, Bibeau F, Azria D, Lemanski C, Assenat E, Duffour J, Ychou M, Reinhold C, Gallix B (2012) MR volumetric measurement of low rectal cancer helps predict tumor response and outcome after combined chemotherapy and radiation therapy. Radiology 263 (2):409-418. https://​doi.​org/​10.​1148/​radiol.​12111263
21.
Zurück zum Zitat Glynne-Jones R, Nilsson PJ, Aschele C, Goh V, Peiffert D, Cervantes A, Arnold D, European Society for Medical O, European Society of Surgical O, European Society of R, Oncology (2014) Anal cancer: ESMO-ESSO-ESTRO clinical practice guidelines for diagnosis, treatment and follow-up. Eur J Surg Oncol 40 (10):1165-1176. https://doi.org/10.1016/j.ejso.2014.07.030 Glynne-Jones R, Nilsson PJ, Aschele C, Goh V, Peiffert D, Cervantes A, Arnold D, European Society for Medical O, European Society of Surgical O, European Society of R, Oncology (2014) Anal cancer: ESMO-ESSO-ESTRO clinical practice guidelines for diagnosis, treatment and follow-up. Eur J Surg Oncol 40 (10):1165-1176. https://​doi.​org/​10.​1016/​j.​ejso.​2014.​07.​030
22.
Zurück zum Zitat Stewart DB, Gaertner WB, Glasgow SC, Herzig DO, Feingold D, Steele SR, Prepared on Behalf of the Clinical Practice Guidelines Committee of the American Society of C, Rectal S (2018) The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for Anal Squamous Cell Cancers (Revised 2018). Dis Colon Rectum 61 (7):755-774. https://doi.org/10.1097/dcr.0000000000001114 Stewart DB, Gaertner WB, Glasgow SC, Herzig DO, Feingold D, Steele SR, Prepared on Behalf of the Clinical Practice Guidelines Committee of the American Society of C, Rectal S (2018) The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for Anal Squamous Cell Cancers (Revised 2018). Dis Colon Rectum 61 (7):755-774. https://​doi.​org/​10.​1097/​dcr.​0000000000001114​
23.
Zurück zum Zitat Moureau-Zabotto L, Vendrely V, Abramowitz L, Borg C, Francois E, Goere D, Huguet F, Peiffert D, Siproudhis L, Ducreux M, Bouche O (2017) Anal cancer: French Intergroup Clinical Practice Guidelines for diagnosis, treatment and follow-up (SNFGE, FFCD, GERCOR, UNICANCER, SFCD, SFED, SFRO, SNFCP). Dig Liver Dis 49 (8):831-840. https://doi.org/10.1016/j.dld.2017.05.011 Moureau-Zabotto L, Vendrely V, Abramowitz L, Borg C, Francois E, Goere D, Huguet F, Peiffert D, Siproudhis L, Ducreux M, Bouche O (2017) Anal cancer: French Intergroup Clinical Practice Guidelines for diagnosis, treatment and follow-up (SNFGE, FFCD, GERCOR, UNICANCER, SFCD, SFED, SFRO, SNFCP). Dig Liver Dis 49 (8):831-840. https://​doi.​org/​10.​1016/​j.​dld.​2017.​05.​011
30.
Zurück zum Zitat AJCC Cancer Staging Manual (2017). 8 edn. Springer International Publishing, AJCC Cancer Staging Manual (2017). 8 edn. Springer International Publishing,
31.
Zurück zum Zitat Parikh J, Shaw A, Grant LA, Schizas AM, Datta V, Williams AB, Griffin N (2011) Anal carcinomas: the role of endoanal ultrasound and magnetic resonance imaging in staging, response evaluation and follow-up. European radiology 21 (4):776-785. https://doi.org/10.1007/s00330-010-1980-7 Parikh J, Shaw A, Grant LA, Schizas AM, Datta V, Williams AB, Griffin N (2011) Anal carcinomas: the role of endoanal ultrasound and magnetic resonance imaging in staging, response evaluation and follow-up. European radiology 21 (4):776-785. https://​doi.​org/​10.​1007/​s00330-010-1980-7
32.
Zurück zum Zitat Reginelli A, Granata V, Fusco R, Granata F, Rega D, Roberto L, Pellino G, Rotondo A, Selvaggi F, Izzo F, Petrillo A, Grassi R (2017) Diagnostic performance of magnetic resonance imaging and 3D endoanal ultrasound in detection, staging and assessment post treatment, in anal cancer. Oncotarget 8 (14):22980-22990. https://doi.org/10.18632/oncotarget.14946 Reginelli A, Granata V, Fusco R, Granata F, Rega D, Roberto L, Pellino G, Rotondo A, Selvaggi F, Izzo F, Petrillo A, Grassi R (2017) Diagnostic performance of magnetic resonance imaging and 3D endoanal ultrasound in detection, staging and assessment post treatment, in anal cancer. Oncotarget 8 (14):22980-22990. https://​doi.​org/​10.​18632/​oncotarget.​14946
35.
Zurück zum Zitat Touboul E, Schlienger M, Buffat L, Lefkopoulos D, Pene F, Parc R, Tiret E, Gallot D, Malafosse M, Laugier A (1994) Epidermoid carcinoma of the anal canal. Results of curative-intent radiation therapy in a series of 270 patients. Cancer 73 (6):1569-1579 Touboul E, Schlienger M, Buffat L, Lefkopoulos D, Pene F, Parc R, Tiret E, Gallot D, Malafosse M, Laugier A (1994) Epidermoid carcinoma of the anal canal. Results of curative-intent radiation therapy in a series of 270 patients. Cancer 73 (6):1569-1579
36.
Zurück zum Zitat Frost DB, Richards PC, Montague ED, Giacco GG, Martin RG (1984) Epidermoid cancer of the anorectum. Cancer 53 (6):1285-1293 Frost DB, Richards PC, Montague ED, Giacco GG, Martin RG (1984) Epidermoid cancer of the anorectum. Cancer 53 (6):1285-1293
37.
Zurück zum Zitat Godlewski G, Prudhomme M (2000) Embryology and anatomy of the anorectum. Basis of surgery. The Surgical clinics of North America 80 (1):319-343 Godlewski G, Prudhomme M (2000) Embryology and anatomy of the anorectum. Basis of surgery. The Surgical clinics of North America 80 (1):319-343
38.
44.
Zurück zum Zitat Benson AB, 3rd, Venook AP, Al-Hawary MM, Cederquist L, Chen YJ, Ciombor KK, Cohen S, Cooper HS, Deming D, Engstrom PF, Grem JL, Grothey A, Hochster HS, Hoffe S, Hunt S, Kamel A, Kirilcuk N, Krishnamurthi S, Messersmith WA, Meyerhardt J, Mulcahy MF, Murphy JD, Nurkin S, Saltz L, Sharma S, Shibata D, Skibber JM, Sofocleous CT, Stoffel EM, Stotsky-Himelfarb E, Willett CG, Wuthrick E, Gregory KM, Freedman-Cass DA (2018) Anal Carcinoma, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology. Journal of the National Comprehensive Cancer Network: JNCCN 16 (7):852-871. https://doi.org/10.6004/jnccn.2018.0060 Benson AB, 3rd, Venook AP, Al-Hawary MM, Cederquist L, Chen YJ, Ciombor KK, Cohen S, Cooper HS, Deming D, Engstrom PF, Grem JL, Grothey A, Hochster HS, Hoffe S, Hunt S, Kamel A, Kirilcuk N, Krishnamurthi S, Messersmith WA, Meyerhardt J, Mulcahy MF, Murphy JD, Nurkin S, Saltz L, Sharma S, Shibata D, Skibber JM, Sofocleous CT, Stoffel EM, Stotsky-Himelfarb E, Willett CG, Wuthrick E, Gregory KM, Freedman-Cass DA (2018) Anal Carcinoma, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology. Journal of the National Comprehensive Cancer Network: JNCCN 16 (7):852-871. https://​doi.​org/​10.​6004/​jnccn.​2018.​0060
45.
Zurück zum Zitat Winton E, Heriot AG, Ng M, Hicks RJ, Hogg A, Milner A, Leong T, Fay M, MacKay J, Drummond E, Ngan SY (2009) The impact of 18-fluorodeoxyglucose positron emission tomography on the staging, management and outcome of anal cancer. British journal of cancer 100 (5):693-700. https://doi.org/10.1038/sj.bjc.6604897 Winton E, Heriot AG, Ng M, Hicks RJ, Hogg A, Milner A, Leong T, Fay M, MacKay J, Drummond E, Ngan SY (2009) The impact of 18-fluorodeoxyglucose positron emission tomography on the staging, management and outcome of anal cancer. British journal of cancer 100 (5):693-700. https://​doi.​org/​10.​1038/​sj.​bjc.​6604897
46.
Zurück zum Zitat Wright JL, Patil SM, Temple LK, Minsky BD, Saltz LB, Goodman KA (2010) Squamous cell carcinoma of the anal canal: patterns and predictors of failure and implications for intensity-modulated radiation treatment planning. International journal of radiation oncology, biology, physics 78 (4):1064-1072 Wright JL, Patil SM, Temple LK, Minsky BD, Saltz LB, Goodman KA (2010) Squamous cell carcinoma of the anal canal: patterns and predictors of failure and implications for intensity-modulated radiation treatment planning. International journal of radiation oncology, biology, physics 78 (4):1064-1072
47.
Zurück zum Zitat Cummings BJ, Keane TJ, O’Sullivan B, Wong CS, Catton CN (1991) Epidermoid anal cancer: treatment by radiation alone or by radiation and 5-fluorouracil with and without mitomycin C. International journal of radiation oncology, biology, physics 21 (5):1115-1125 Cummings BJ, Keane TJ, O’Sullivan B, Wong CS, Catton CN (1991) Epidermoid anal cancer: treatment by radiation alone or by radiation and 5-fluorouracil with and without mitomycin C. International journal of radiation oncology, biology, physics 21 (5):1115-1125
48.
Zurück zum Zitat Flam M, John M, Pajak TF, Petrelli N, Myerson R, Doggett S, Quivey J, Rotman M, Kerman H, Coia L, Murray K (1996) Role of mitomycin in combination with fluorouracil and radiotherapy, and of salvage chemoradiation in the definitive nonsurgical treatment of epidermoid carcinoma of the anal canal: results of a phase III randomized intergroup study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 14 (9):2527-2539. https://doi.org/10.1200/jco.1996.14.9.2527 Flam M, John M, Pajak TF, Petrelli N, Myerson R, Doggett S, Quivey J, Rotman M, Kerman H, Coia L, Murray K (1996) Role of mitomycin in combination with fluorouracil and radiotherapy, and of salvage chemoradiation in the definitive nonsurgical treatment of epidermoid carcinoma of the anal canal: results of a phase III randomized intergroup study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 14 (9):2527-2539. https://​doi.​org/​10.​1200/​jco.​1996.​14.​9.​2527
49.
Zurück zum Zitat Bartelink H, Roelofsen F, Eschwege F, Rougier P, Bosset JF, Gonzalez DG, Peiffert D, van Glabbeke M, Pierart M (1997) Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a phase III randomized trial of the European Organization for Research and Treatment of Cancer Radiotherapy and Gastrointestinal Cooperative Groups. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 15 (5):2040-2049. https://doi.org/10.1200/jco.1997.15.5.2040 Bartelink H, Roelofsen F, Eschwege F, Rougier P, Bosset JF, Gonzalez DG, Peiffert D, van Glabbeke M, Pierart M (1997) Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a phase III randomized trial of the European Organization for Research and Treatment of Cancer Radiotherapy and Gastrointestinal Cooperative Groups. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 15 (5):2040-2049. https://​doi.​org/​10.​1200/​jco.​1997.​15.​5.​2040
50.
Zurück zum Zitat Northover J, Glynne-Jones R, Sebag-Montefiore D, James R, Meadows H, Wan S, Jitlal M, Ledermann J (2010) Chemoradiation for the treatment of epidermoid anal cancer: 13-year follow-up of the first randomised UKCCCR Anal Cancer Trial (ACT I). British journal of cancer 102 (7):1123-1128. https://doi.org/10.1038/sj.bjc.6605605 Northover J, Glynne-Jones R, Sebag-Montefiore D, James R, Meadows H, Wan S, Jitlal M, Ledermann J (2010) Chemoradiation for the treatment of epidermoid anal cancer: 13-year follow-up of the first randomised UKCCCR Anal Cancer Trial (ACT I). British journal of cancer 102 (7):1123-1128. https://​doi.​org/​10.​1038/​sj.​bjc.​6605605
52.
Zurück zum Zitat Deutsch E, Lemanski C, Pignon JP, Levy A, Delarochefordiere A, Martel-Lafay I, Rio E, Malka D, Conroy T, Miglianico L, Becouarn Y, Malekzadeh K, Paris E, Juzyna B, Ezra P, Azria D (2013) Unexpected toxicity of cetuximab combined with conventional chemoradiotherapy in patients with locally advanced anal cancer: results of the UNICANCER ACCORD 16 phase II trial. Ann Oncol 24 (11):2834-2838. https://doi.org/10.1093/annonc/mdt368 Deutsch E, Lemanski C, Pignon JP, Levy A, Delarochefordiere A, Martel-Lafay I, Rio E, Malka D, Conroy T, Miglianico L, Becouarn Y, Malekzadeh K, Paris E, Juzyna B, Ezra P, Azria D (2013) Unexpected toxicity of cetuximab combined with conventional chemoradiotherapy in patients with locally advanced anal cancer: results of the UNICANCER ACCORD 16 phase II trial. Ann Oncol 24 (11):2834-2838. https://​doi.​org/​10.​1093/​annonc/​mdt368
53.
Zurück zum Zitat Eng C, Crane CH, Rosner GL, et al. (2005) A phase II study of capecitabine plus oxaliplatin and radiation therapy (XELOX-RT) in squamous cell carcinoma of the anal canal: a preliminary toxicity analysis. Proc ASCO/AGA/ASTRO/SSO GI Symposium 2:192 (abstr). Eng C, Crane CH, Rosner GL, et al. (2005) A phase II study of capecitabine plus oxaliplatin and radiation therapy (XELOX-RT) in squamous cell carcinoma of the anal canal: a preliminary toxicity analysis. Proc ASCO/AGA/ASTRO/SSO GI Symposium 2:192 (abstr).
54.
Zurück zum Zitat Sebag-Montefiore D, Meadows HM, Cunningham D, Plowman PN, Hurman DC, Davidson N, Grieve R, Levine E, Glynne-Jones R (2012) Three cytotoxic drugs combined with pelvic radiation and as maintenance chemotherapy for patients with squamous cell carcinoma of the anus (SCCA): long-term follow-up of a phase II pilot study using 5-fluorouracil, mitomycin C and cisplatin. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 104 (2):155-160. https://doi.org/10.1016/j.radonc.2012.06.006 Sebag-Montefiore D, Meadows HM, Cunningham D, Plowman PN, Hurman DC, Davidson N, Grieve R, Levine E, Glynne-Jones R (2012) Three cytotoxic drugs combined with pelvic radiation and as maintenance chemotherapy for patients with squamous cell carcinoma of the anus (SCCA): long-term follow-up of a phase II pilot study using 5-fluorouracil, mitomycin C and cisplatin. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 104 (2):155-160. https://​doi.​org/​10.​1016/​j.​radonc.​2012.​06.​006
55.
Zurück zum Zitat Kachnic LA, Winter K, Myerson RJ, Goodyear MD, Willins J, Esthappan J, Haddock MG, Rotman M, Parikh PJ, Safran H, Willett CG (2013) RTOG 0529: a phase 2 evaluation of dose-painted intensity modulated radiation therapy in combination with 5-fluorouracil and mitomycin-C for the reduction of acute morbidity in carcinoma of the anal canal. International journal of radiation oncology, biology, physics 86 (1):27-33. https://doi.org/10.1016/j.ijrobp.2012.09.023 Kachnic LA, Winter K, Myerson RJ, Goodyear MD, Willins J, Esthappan J, Haddock MG, Rotman M, Parikh PJ, Safran H, Willett CG (2013) RTOG 0529: a phase 2 evaluation of dose-painted intensity modulated radiation therapy in combination with 5-fluorouracil and mitomycin-C for the reduction of acute morbidity in carcinoma of the anal canal. International journal of radiation oncology, biology, physics 86 (1):27-33. https://​doi.​org/​10.​1016/​j.​ijrobp.​2012.​09.​023
Metadaten
Titel
MR staging of anal cancer: what the radiologist needs to know
verfasst von
Jennifer S. Golia Pernicka
Shannon P. Sheedy
Randy D. Ernst
Bruce D. Minsky
Dhakshinamoorthy Ganeshan
Gaiane M. Rauch
Publikationsdatum
30.04.2019
Verlag
Springer US
Erschienen in
Abdominal Radiology / Ausgabe 11/2019
Print ISSN: 2366-004X
Elektronische ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-019-02020-4

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