Introduction
Materials and methods
Subjects
MSNA, HR, and BP recording
Measurement and analysis
Results
FTLD (n = 10) | ALS (n = 12) | Controls (n = 16) |
p values | |
---|---|---|---|---|
Age (years) | 71.6 ± 4.6 | 71.4 ± 4.6 | 71.9 ± 5.9 | 0.8639 |
At rest | ||||
HR (/min) | 73.1 ± 12.2 | 73.5 ± 11.3 | 76.5 ± 10.6 | 0.4820 |
MBP (mmHg) | 92.6 ± 11.6 | 94.9 ± 19.3 | 93.0 ± 24.2 | 0.8898 |
MSNA (b/100 HB) | 83.4 ± 13.9a
| 81.2 ± 12.8b
| 62.8 ± 14.1 | 0.0013 |
Head-up tilting | ||||
ΔHR (/min) | +2.5 ± 1.2c
| +3.4 ± 2.2d
| +7.9 ± 4.2 | 0.0376 |
ΔMBP (mmHg) | +11.5 ± 3.2c
| +9.0 ± 1.0d
| +15.4 ± 10.8 | 0.0389 |
ΔMSNA (b/100 HB) | +2.8 ± 1.0a
| +3.8 ± 2.1b
| +7.9 ± 4.2 | 0.0057 |