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27.02.2023 | Review Article

Neonatal hematological parameters: the translational aspect of developmental hematopoiesis

verfasst von: Rozeta Sokou, Stavroula Parastatidou, Aikaterini Konstantinidi, Georgios Ioakeimidis, Andreas G. Tsantes, Dimitra Houhoula, Nicoletta Iacovidou, Argirios E. Tsantes

Erschienen in: Annals of Hematology | Ausgabe 4/2023

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Abstract

Hematopoiesis is a process constantly evolving from fetal life through adulthood. Neonates present with qualitative and quantitative differences in hematological parameters compared to older children and adults, reflecting developmental changes in hematopoiesis correlated with gestational age. Such differences are more intense for preterm and small-for-gestational-age neonates or neonates with intrauterine growth restriction. This review article is aimed at describing the hematologic differences among neonatal subgroups and the major underlying pathogenic mechanisms. Issues that should be taken into account when interpreting neonatal hematological parameters are also highlighted.

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Titel: Neonatal hematological parameters: the translational aspect of developmental hematopoiesis
verfasst von: Rozeta Sokou
Stavroula Parastatidou
Aikaterini Konstantinidi
Georgios Ioakeimidis
Andreas G. Tsantes
Dimitra Houhoula
Nicoletta Iacovidou
Argirios E. Tsantes
Publikationsdatum: 27.02.2023
Verlag: Springer Berlin Heidelberg
Erschienen in: Annals of Hematology / Ausgabe 4/2023
Print ISSN: 0939-5555
Elektronische ISSN: 1432-0584
DOI: https://doi.org/10.1007/s00277-023-05144-2

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