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Erschienen in: Critical Care 5/2012

01.10.2012 | Commentary

New conclusive data on human myocardial dysfunction induced by acidosis

verfasst von: Antoine Kimmoun, Nicolas Ducrocq, Bruno Levy

Erschienen in: Critical Care | Ausgabe 5/2012

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Abstract

Acidosis is one of the major consequences of hemodynamic instability in shock state patients directly associated with multiple organ failure evolution and death. Most studies on the hemodynamic consequences of acidosis have been experimental, nonhuman studies with severe acidosis, and thus far from the most common clinical situations. Schotola and colleagues offer a new approach to human failing myocardium where the authors highlight, ex vivo, the deleterious hemodynamic consequences of mild acidosis. Their work strengthens the current view of the urgent need to discover new efficient and nondeleterious therapy for the treatment of acidosis.
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Metadaten
Titel
New conclusive data on human myocardial dysfunction induced by acidosis
verfasst von
Antoine Kimmoun
Nicolas Ducrocq
Bruno Levy
Publikationsdatum
01.10.2012
Verlag
BioMed Central
Erschienen in
Critical Care / Ausgabe 5/2012
Elektronische ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc11520

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