Erschienen in:
01.04.2008 | Poster presentation
Noradrenaline for treatment of endotoxemic shock in pigs is associated with improved hepatic mitochondrial respiration
verfasst von:
T Regueira, S Djafarzadeh, PM Lepper, B Bänziger, S Brandt, J Takala, SM Jakob
Erschienen in:
Critical Care
|
Sonderheft 2/2008
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Excerpt
The optimal mean arterial blood pressure (MAP) for sepsis resuscitation remains unclear. Growing evidence suggests that mitochondrial dysfunction plays a role in the pathogenesis of sepsis-induced organ failures. The aim of this study was to evaluate the effect of progressively increasing levels of MAP, achieved by the use of noradrenaline (NA) on liver mitochondrial function during sepsis. …