Background
Methods
Statistical analysis
Results
Variable | Number | Results, n (%) |
---|---|---|
Age (years), mean (SD) | 693 | 49.84 (14.63) |
Gender | ||
Male | 693 | 346 (49) |
Female | 347 (51) | |
Indication | ||
Screening | 693 | 36 (5.2) |
Follow-up | 116 (16.7) | |
Diagnostic | 541 (78.1) | |
BMI (kg/m2) | ||
< 18.5 | 693 | 34 (4.9) |
18.5–24.9 | 211 (30.4) | |
25.0–29.9 | 260 (37.5) | |
30.0–34.9 | 143 (20.6) | |
= > 35.0 | 45 (6.5) | |
Medical history of any disease | ||
Anemia | 102 (14.7) | |
Asthma | 20 (2.9) | |
Arthritis | 19 (2.74) | |
Thyroid Disorder | 43 (6.2) | |
Type 1 or 2 Diabetes | 91 (13.1) | |
High Blood Pressure | 152 (21.9) | |
High Cholesterol | 68 (12.7) | |
Gastrointestinal symptom | 277 (32.76) | |
Migraine | 14 (2) | |
Heart Attack | 79 (11.4) | |
Kidney Disease | 34 (4.9) | |
Liver Disease | 75 (10.8) | |
Neurological Disease | 57 (8.2) | |
Stomach Colon Disease | 68 (9.8) | |
Nothing | 138 (19.9) | |
Fx of cancer | 570 (82.2) | |
Fx of colon cancer | 125 (18.03) | |
Fx of colon cancer (Relative) | ||
Mother | 125 | 30 (20.4) |
Father | 27 (18.4) | |
Brother | 22 (15) | |
Sister | 21 (14.3) | |
Children | 0 | |
Second relative | 47 (32) | |
Personal history of any cancer | 693 | 123 (17.7) |
Positive Hx of Drug | 53 (7.6) | |
Positive Hx of Smoking | 131 (18.9) | |
Positive Hx of Alcohol | 30 (3.1) | |
Result of pathology/colonoscopy | ||
Normal Colonoscopy | 693 | 515 (74.3) |
Tubular adenoma | 92 (13.3) | |
Tubulovillous adenomas | 21 (3) | |
Villous adenoma | 2 (0.3) | |
Sessile serrated adenoma /polyp | 4 (0.6) | |
Serrated polyposis = Hyperplastic polyp syndrome | 0 | |
Traditional serrated adenoma | 2 (0.3) | |
Hyperplastic polyp | 14 (2) | |
Adenocarcinoma | 30 (4.3) | |
Benign | 13 (1.9) | |
Positive polyp | 149 (21.5) | |
Positive adenoma | 115 (16.6) | |
Adenoma location | ||
Anal | 115 | 2 (1.4) |
Rectum | 27 (19.4) | |
Sigmoid | 51 (36.7) | |
Transvers colon | 12 (8.6) | |
Descending colon | 15 (10.8) | |
Ascending colon | 22 (15.8) | |
Cecum | 6 (4.3) | |
All of the colon | 4 (2.8) | |
Adenoma size ≥1 | 115 | 101 (87.8) |
High grade dysplasia | 115 | 11 (9.6) |
Normal Colonoscopy | Adenoma Positive | p value | |||
---|---|---|---|---|---|
Number | Results | Number | Results | ||
Age (years), Mean (SD)* | 515 | 47.5 (14.4) | 115 | 55.9 (13.3) | 1.48E-08 |
Male, n (%) | 251 (48.7) | 65 (56.5) | 0.1596 | ||
BMI (kg/m2), Mean (SD) | 27.6 (14.4) | 26.4 (5.4) | 0.1528 | ||
BMI (kg/m2) ≥ 25, n (%)* | 257 (49.9) | 70 (60.9) | 0.0429 | ||
Positive Hx of type.1.or.2.Diabetes* | 56 (10.9) | 22 (19.1) | 0.023 | ||
Positive Hx of colon disease, n (%) | 48 (9.3) | 12 (10.4) | 0.8474 | ||
Positive Hx of colon polyp, n (%) | 41 (8) | 11 (9.6) | 0.7056 | ||
Positive Hx of colon cancer family*, n (%) | 85 (16.5) | 29 (25.2) | 0.0394 | ||
Positive Hx of Drug*, n (%) | 23 (4.5) | 11 (9.5) | 0.05 | ||
Positive Hx of Smoking, n (%) | 99 (19.22) | 21 (18.26) | 0.9153 |
Normal Colonoscopy | Adenocarcinoma | p value | |||
---|---|---|---|---|---|
Number | Results | Number | Results | ||
Age (year), Mean (SD)* | 515 | 47.5 (14.4) | 29 | 59.2 (15) | 2.2e-16 |
Male, n (%) | 251 (48.7) | 18 (62.1) | 0.2277 | ||
BMI (kg/m2), Mean (SD)* | 27.6 (14.4) | 24.7 (5.2) | 0.01467 | ||
BMI (kg/m2) ≥25, n (%) | 257 (49.9) | 15 (51.7) | 0.8486 | ||
Positive Hx of type.1.or.2.Diabetes | 56 (10.9) | 3 (10.3) | 0.9290 | ||
Positive Hx of colon disease, n (%) | 48 (9.3) | 4 (13.8) | 0.6835 | ||
Positive Hx of colon polyp, n (%) | 41 (8) | 5 (17.2) | 0.1601 | ||
Positive Hx of colon cancer family, n (%) | 85 (16.5) | 4 (13.8) | 0.8393 | ||
Positive Hx of Drug, n (%) | 23 (4.5) | 3 (10.3) | 0.3190 | ||
Positive Hx of Smoking, n (%) | 99 (19.22) | 7 (24.13) | 0.6824 |
DOR | [95% CI] | p value | |
---|---|---|---|
Direct disease | |||
Anemia | 0.575 | 0.296–1.119 | 0.8 |
Blood Clots | 0.889 | 0.042–18.646 | 0.4 |
Thyroid Disorder | 0.623 | 0.239–1.628 | 0.7 |
Sexually Transmitted | 0.294 | 0.017–5.176 | 0.5 |
Type 1 or 2 Diabetes * | 1.831 | 1.058–3.169 | 0.023 |
Gynecological Disease | 0.637 | 0.078–5.225 | 0.7 |
Acromegaly | 0.492 | 0.026–9.203 | 0.8 |
Gastrointestinal symptom | 0.680 | 0.432–1.071 | 0.2 |
Stomach Colon Disease | 1.133 | 0.581–2.210 | 0.8 |
Indirect disease | |||
High Blood Pressure | 1.542 | 0.972–2.446 | 0.1 |
High Cholesterol | 1.381 | 0.781–2.441 | 0.3 |
Heart Disease | 1.325 | 0.730–2.405 | 0.4 |
Liver Disease | 1.503 | 0.822–2.748 | 0.2 |