Skip to main content
Erschienen in: Pediatric Radiology 2/2011

01.09.2011 | ALARA-CT

Oncological imaging: tumor surveillance in children

verfasst von: Sue C. Kaste

Erschienen in: Pediatric Radiology | Sonderheft 2/2011

Einloggen, um Zugang zu erhalten

Abstract

As the need for accurate diagnostic imaging often continues throughout a cancer survivor’s life, imaging methods with the least toxicity must be used so as to provide needed information without contributing to long-term sequelae that might compound toxicities inherent with the primary disease and its treatment. In this regard, the costs, benefits and potential risks of post-therapy monitoring for disease recurrence warrant periodic review. Unfortunately, few analyses are available regarding the impact of surveillance imaging on the detection of disease recurrence, salvage rates of relapse disease and long-term survival outcomes for pediatric cancer survivors. This review will examine the role and limitations of surveillance imaging in pediatric oncology.
Literatur
1.
Zurück zum Zitat Mariotto AB, Rowland JH, Yabroff KR et al (2009) Long-term survivors of childhood cancers in the United States. Cancer Epidemiol Biomarkers Prev 18:1033–1040PubMedCrossRef Mariotto AB, Rowland JH, Yabroff KR et al (2009) Long-term survivors of childhood cancers in the United States. Cancer Epidemiol Biomarkers Prev 18:1033–1040PubMedCrossRef
2.
Zurück zum Zitat Bhatia S, Yasui Y, Robison LL et al (2003) High risk of subsequent neoplasms continues with extended follow-up of childhood Hodgkin’s disease: report from the Late Effects Study Group. J Clin Oncol 21:4386–4394PubMedCrossRef Bhatia S, Yasui Y, Robison LL et al (2003) High risk of subsequent neoplasms continues with extended follow-up of childhood Hodgkin’s disease: report from the Late Effects Study Group. J Clin Oncol 21:4386–4394PubMedCrossRef
3.
Zurück zum Zitat Bhatti P, Veiga LH, Ronckers CX et al (2010) Risk of second primary thyroid cancer after radiotherapy for a childhood cancer in a large cohort study: an update from the childhood cancer survivor study. Radiat Res 174:741–752PubMedCrossRef Bhatti P, Veiga LH, Ronckers CX et al (2010) Risk of second primary thyroid cancer after radiotherapy for a childhood cancer in a large cohort study: an update from the childhood cancer survivor study. Radiat Res 174:741–752PubMedCrossRef
4.
Zurück zum Zitat Inskip PD, Curtis RE (2007) New malignancies following childhood cancer in the United States, 1973–2002. Int J Cancer 121:2233–2240PubMedCrossRef Inskip PD, Curtis RE (2007) New malignancies following childhood cancer in the United States, 1973–2002. Int J Cancer 121:2233–2240PubMedCrossRef
5.
Zurück zum Zitat Reaman GH (2009) What, why, and when we image: considerations for diagnostic imaging and clinical research in the Children’s Oncology Group. Pediatr Radiol 39(Suppl 1):S42–S45PubMedCrossRef Reaman GH (2009) What, why, and when we image: considerations for diagnostic imaging and clinical research in the Children’s Oncology Group. Pediatr Radiol 39(Suppl 1):S42–S45PubMedCrossRef
6.
Zurück zum Zitat Meadows AT, Friedman DL, Neglia JP et al (2009) Second neoplasms in survivors of childhood cancer: findings from the childhood cancer survivor study cohort. J Clin Oncol 27:2356–2362PubMedCrossRef Meadows AT, Friedman DL, Neglia JP et al (2009) Second neoplasms in survivors of childhood cancer: findings from the childhood cancer survivor study cohort. J Clin Oncol 27:2356–2362PubMedCrossRef
7.
Zurück zum Zitat Bowers DC, Adhikari S, El-Khashab YM et al (2009) Survey of long-term follow-up programs in the United States for survivors of childhood brain tumors. Pediatr Blood Cancer 53:1295–1301PubMedCrossRef Bowers DC, Adhikari S, El-Khashab YM et al (2009) Survey of long-term follow-up programs in the United States for survivors of childhood brain tumors. Pediatr Blood Cancer 53:1295–1301PubMedCrossRef
8.
Zurück zum Zitat Minn AY, Pollock BH, Garzarella L et al (2001) Surveillance neuroimaging to detect relapse in childhood brain tumors: a pediatric oncology group study. J Clin Oncol 19:4135–4140PubMed Minn AY, Pollock BH, Garzarella L et al (2001) Surveillance neuroimaging to detect relapse in childhood brain tumors: a pediatric oncology group study. J Clin Oncol 19:4135–4140PubMed
9.
Zurück zum Zitat Lee AI, Zuckerman DS, Van den Abbeele AD et al (2010) Surveillance imaging of Hodgkin lymphoma patients in first remission: a clinical and economic analysis. Cancer 116:3835–3842PubMedCrossRef Lee AI, Zuckerman DS, Van den Abbeele AD et al (2010) Surveillance imaging of Hodgkin lymphoma patients in first remission: a clinical and economic analysis. Cancer 116:3835–3842PubMedCrossRef
10.
Zurück zum Zitat Postovsky S, Barzilai M, Meller I et al (2008) Does regular follow-up influence the survival of patients with sarcoma after recurrence? The Miri Shitrit pediatric oncology department experience. J Pediatr Hematol Oncol 30:189–195PubMedCrossRef Postovsky S, Barzilai M, Meller I et al (2008) Does regular follow-up influence the survival of patients with sarcoma after recurrence? The Miri Shitrit pediatric oncology department experience. J Pediatr Hematol Oncol 30:189–195PubMedCrossRef
11.
Zurück zum Zitat Kovanlikaya A, Karabay N, Cakmakci H et al (2003) Surveillance imaging and cost effectivity in pediatric brain tumors. Eur J Radiol 47:188–192PubMedCrossRef Kovanlikaya A, Karabay N, Cakmakci H et al (2003) Surveillance imaging and cost effectivity in pediatric brain tumors. Eur J Radiol 47:188–192PubMedCrossRef
12.
Zurück zum Zitat Biasotti S, Garaventa A, Padovani P et al (2005) Role of active follow-up for early diagnosis of relapse after elective end of therapies. Pediatr Blood Cancer 45:781–786PubMedCrossRef Biasotti S, Garaventa A, Padovani P et al (2005) Role of active follow-up for early diagnosis of relapse after elective end of therapies. Pediatr Blood Cancer 45:781–786PubMedCrossRef
13.
Zurück zum Zitat Owens CM, Brisse HJ, Olsen OE et al (2008) Bilateral disease and new trends in Wilms tumour. Pediatr Radiol 38:30–39PubMedCrossRef Owens CM, Brisse HJ, Olsen OE et al (2008) Bilateral disease and new trends in Wilms tumour. Pediatr Radiol 38:30–39PubMedCrossRef
14.
Zurück zum Zitat Guadagnolo BA, Punglia RS, Kuntz KM et al (2006) Cost-effectiveness analysis of computerized tomography in the routine follow-up of patients after primary treatment for Hodgkin’s disease. J Clin Oncol 24:4116–4122PubMedCrossRef Guadagnolo BA, Punglia RS, Kuntz KM et al (2006) Cost-effectiveness analysis of computerized tomography in the routine follow-up of patients after primary treatment for Hodgkin’s disease. J Clin Oncol 24:4116–4122PubMedCrossRef
15.
Zurück zum Zitat Torrey MJ, Poen JC, Hoppe RT (1997) Detection of relapse in early-stage Hodgkin’s disease: role of routine follow-up studies. J Clin Oncol 15:1123–1130PubMed Torrey MJ, Poen JC, Hoppe RT (1997) Detection of relapse in early-stage Hodgkin’s disease: role of routine follow-up studies. J Clin Oncol 15:1123–1130PubMed
16.
Zurück zum Zitat Dryver ET, Jernstrom H, Tompkins K et al (2003) Follow-up of patients with Hodgkin’s disease following curative treatment: the routine CT scan is of little value. Br J Cancer 89:482–486PubMedCrossRef Dryver ET, Jernstrom H, Tompkins K et al (2003) Follow-up of patients with Hodgkin’s disease following curative treatment: the routine CT scan is of little value. Br J Cancer 89:482–486PubMedCrossRef
17.
Zurück zum Zitat Howell L, Mensah A, Brennan B et al (2005) Detection of recurrence in childhood solid tumors. Cancer 103:1274–1279PubMedCrossRef Howell L, Mensah A, Brennan B et al (2005) Detection of recurrence in childhood solid tumors. Cancer 103:1274–1279PubMedCrossRef
18.
Zurück zum Zitat Chong AL, Grant RM, Ahmed BA et al (2010) Imaging in pediatric patients: time to think again about surveillance. Pediatr Blood Cancer 55:407–413PubMedCrossRef Chong AL, Grant RM, Ahmed BA et al (2010) Imaging in pediatric patients: time to think again about surveillance. Pediatr Blood Cancer 55:407–413PubMedCrossRef
19.
Zurück zum Zitat Nathan PC, Ness KK, Mahoney MC et al (2010) Screening and surveillance for second malignant neoplasms in adult survivors of childhood cancer: a report from the childhood cancer survivor study. Ann Intern Med 153:442–451PubMed Nathan PC, Ness KK, Mahoney MC et al (2010) Screening and surveillance for second malignant neoplasms in adult survivors of childhood cancer: a report from the childhood cancer survivor study. Ann Intern Med 153:442–451PubMed
20.
Zurück zum Zitat Meadows AT (2003) Pediatric cancer survivors: Past history and future challenges. Curr Probl Cancer 27:112–126PubMedCrossRef Meadows AT (2003) Pediatric cancer survivors: Past history and future challenges. Curr Probl Cancer 27:112–126PubMedCrossRef
21.
Zurück zum Zitat Hudson MM, Mulrooney DA, Bowers DC et al (2009) High-risk populations identified in childhood cancer survivor study investigations: implications for risk-based surveillance. J Clin Oncol 27:2405–2414PubMedCrossRef Hudson MM, Mulrooney DA, Bowers DC et al (2009) High-risk populations identified in childhood cancer survivor study investigations: implications for risk-based surveillance. J Clin Oncol 27:2405–2414PubMedCrossRef
22.
Zurück zum Zitat Kaste SC (2008) Skeletal toxicities of treatment in children with cancer. Pediatr Blood Cancer 50(2 Suppl):469–473PubMedCrossRef Kaste SC (2008) Skeletal toxicities of treatment in children with cancer. Pediatr Blood Cancer 50(2 Suppl):469–473PubMedCrossRef
23.
Zurück zum Zitat Karimova EJ, Rai SN, Ingle D et al (2006) MRI of knee osteonecrosis in children with leukemia and lymphoma: Part 2, clinical and imaging patterns. AJR 186:477–482PubMedCrossRef Karimova EJ, Rai SN, Ingle D et al (2006) MRI of knee osteonecrosis in children with leukemia and lymphoma: Part 2, clinical and imaging patterns. AJR 186:477–482PubMedCrossRef
24.
Zurück zum Zitat LA Mattano J, Sather HN, Trigg ME et al (2000) Osteonecrosis as a complication of treating acute lymphoblastic leukemia in children: a report from the children’s cancer group. J Clin Oncol 18:3262–3272PubMed LA Mattano J, Sather HN, Trigg ME et al (2000) Osteonecrosis as a complication of treating acute lymphoblastic leukemia in children: a report from the children’s cancer group. J Clin Oncol 18:3262–3272PubMed
25.
Zurück zum Zitat Sala A, Mattano LA Jr, Barr RD (2007) Osteonecrosis in children and adolescents with cancer—an adverse effect of systemic therapy. Eur J Cancer 43:683–689PubMedCrossRef Sala A, Mattano LA Jr, Barr RD (2007) Osteonecrosis in children and adolescents with cancer—an adverse effect of systemic therapy. Eur J Cancer 43:683–689PubMedCrossRef
26.
Zurück zum Zitat Barr RD, Sala A (2008) Osteonecrosis in children and adolescents with cancer. Pediatr Blood Cancer 50(2 Suppl):483–485PubMedCrossRef Barr RD, Sala A (2008) Osteonecrosis in children and adolescents with cancer. Pediatr Blood Cancer 50(2 Suppl):483–485PubMedCrossRef
27.
28.
Zurück zum Zitat Guppy AE, Tebbutt NC, Norman A et al (2003) The role of surveillance CT scans in patients with diffuse large B-cell non-Hodgkin’s lymphoma. Leuk Lymphoma 44:123–125PubMedCrossRef Guppy AE, Tebbutt NC, Norman A et al (2003) The role of surveillance CT scans in patients with diffuse large B-cell non-Hodgkin’s lymphoma. Leuk Lymphoma 44:123–125PubMedCrossRef
29.
Zurück zum Zitat Elis A, Blickstein D, Klein O et al (2002) Detection of relapse in non-Hodgkin’s lymphoma: role of routine follow-up studies. Am J Hematol 69:41–44PubMedCrossRef Elis A, Blickstein D, Klein O et al (2002) Detection of relapse in non-Hodgkin’s lymphoma: role of routine follow-up studies. Am J Hematol 69:41–44PubMedCrossRef
30.
Zurück zum Zitat de Graaf N, Hew JM, Fock JM et al (2002) Predictive value of clinical evaluation in the follow-up of children with a brain tumor. Med Pediatr Oncol 38:254–257PubMedCrossRef de Graaf N, Hew JM, Fock JM et al (2002) Predictive value of clinical evaluation in the follow-up of children with a brain tumor. Med Pediatr Oncol 38:254–257PubMedCrossRef
32.
Zurück zum Zitat Frush DP, Goske MJ, Hernanz-Schulman M (2008) Computed tomography and radiation exposure. N Engl J Med 358:851–853PubMed Frush DP, Goske MJ, Hernanz-Schulman M (2008) Computed tomography and radiation exposure. N Engl J Med 358:851–853PubMed
33.
Zurück zum Zitat Frush DP (2009) Radiation, CT, and children: the simple answer is … it’s complicated. Radiology 252:4–6PubMedCrossRef Frush DP (2009) Radiation, CT, and children: the simple answer is … it’s complicated. Radiology 252:4–6PubMedCrossRef
34.
Zurück zum Zitat Brenner D, Elliston C, Hall E et al (2001) Estimated risks of radiation-induced fatal cancer from pediatric CT. AJR 176:289–296PubMed Brenner D, Elliston C, Hall E et al (2001) Estimated risks of radiation-induced fatal cancer from pediatric CT. AJR 176:289–296PubMed
35.
Zurück zum Zitat Huda W (2004) Assessment of the problem: pediatric doses in screen-film and digital radiography. Pediatr Radiol 34(Suppl 3):S173–S182PubMedCrossRef Huda W (2004) Assessment of the problem: pediatric doses in screen-film and digital radiography. Pediatr Radiol 34(Suppl 3):S173–S182PubMedCrossRef
36.
Zurück zum Zitat Huda W (2007) Radiation doses and risks in chest computed tomography examinations. Proc Am Thorac Soc 4:316–320PubMedCrossRef Huda W (2007) Radiation doses and risks in chest computed tomography examinations. Proc Am Thorac Soc 4:316–320PubMedCrossRef
37.
Zurück zum Zitat Brody AS, Frush DP, Huda W et al (2007) Radiation risk to children from computed tomography. Pediatrics 120:677–682PubMedCrossRef Brody AS, Frush DP, Huda W et al (2007) Radiation risk to children from computed tomography. Pediatrics 120:677–682PubMedCrossRef
38.
Zurück zum Zitat Girshin M, Shapiro V, Rhee A et al (2009) Increased risk of general anesthesia for high-risk patients undergoing magnetic resonance imaging. J Comput Assist Tomogr 33:312–315PubMedCrossRef Girshin M, Shapiro V, Rhee A et al (2009) Increased risk of general anesthesia for high-risk patients undergoing magnetic resonance imaging. J Comput Assist Tomogr 33:312–315PubMedCrossRef
39.
Zurück zum Zitat Kwee TC, Takahara T, Luijten PR et al (2010) ADC measurements of lymph nodes: inter- and intra-observer reproducibility study and an overview of the literature. Eur J Radiol 75:215–220PubMedCrossRef Kwee TC, Takahara T, Luijten PR et al (2010) ADC measurements of lymph nodes: inter- and intra-observer reproducibility study and an overview of the literature. Eur J Radiol 75:215–220PubMedCrossRef
40.
Zurück zum Zitat Ley S, Ley-Zaporozhan J, Schenk JP (2009) Whole-body MRI in the pediatric patient. Eur J Radiol 70:442–451PubMedCrossRef Ley S, Ley-Zaporozhan J, Schenk JP (2009) Whole-body MRI in the pediatric patient. Eur J Radiol 70:442–451PubMedCrossRef
41.
Zurück zum Zitat Darge K, Jaramillo D, Siegel MJ (2008) Whole-body MRI in children: current status and future applications. Eur J Radiol 68:289–298PubMedCrossRef Darge K, Jaramillo D, Siegel MJ (2008) Whole-body MRI in children: current status and future applications. Eur J Radiol 68:289–298PubMedCrossRef
Metadaten
Titel
Oncological imaging: tumor surveillance in children
verfasst von
Sue C. Kaste
Publikationsdatum
01.09.2011
Verlag
Springer-Verlag
Erschienen in
Pediatric Radiology / Ausgabe Sonderheft 2/2011
Print ISSN: 0301-0449
Elektronische ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-011-2108-1

Weitere Artikel der Sonderheft 2/2011

Pediatric Radiology 2/2011 Zur Ausgabe

Screening-Mammografie offenbart erhöhtes Herz-Kreislauf-Risiko

26.04.2024 Mammografie Nachrichten

Routinemäßige Mammografien helfen, Brustkrebs frühzeitig zu erkennen. Anhand der Röntgenuntersuchung lassen sich aber auch kardiovaskuläre Risikopatientinnen identifizieren. Als zuverlässiger Anhaltspunkt gilt die Verkalkung der Brustarterien.

S3-Leitlinie zu Pankreaskrebs aktualisiert

23.04.2024 Pankreaskarzinom Nachrichten

Die Empfehlungen zur Therapie des Pankreaskarzinoms wurden um zwei Off-Label-Anwendungen erweitert. Und auch im Bereich der Früherkennung gibt es Aktualisierungen.

Fünf Dinge, die im Kindernotfall besser zu unterlassen sind

18.04.2024 Pädiatrische Notfallmedizin Nachrichten

Im Choosing-Wisely-Programm, das für die deutsche Initiative „Klug entscheiden“ Pate gestanden hat, sind erstmals Empfehlungen zum Umgang mit Notfällen von Kindern erschienen. Fünf Dinge gilt es demnach zu vermeiden.

„Nur wer sich gut aufgehoben fühlt, kann auch für Patientensicherheit sorgen“

13.04.2024 Klinik aktuell Kongressbericht

Die Teilnehmer eines Forums beim DGIM-Kongress waren sich einig: Fehler in der Medizin sind häufig in ungeeigneten Prozessen und mangelnder Kommunikation begründet. Gespräche mit Patienten und im Team können helfen.

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.