Skip to main content
Erschienen in: Abdominal Radiology 1/2013

01.02.2013

Perspective on radiation risk in CT imaging

verfasst von: Joel G. Fletcher, James M. Kofler, John A. Coburn, David H. Bruining, Cynthia H. McCollough

Erschienen in: Abdominal Radiology | Ausgabe 1/2013

Einloggen, um Zugang zu erhalten

Abstract

Awareness of and communication about issues related to radiation dose are beneficial for patients, clinicians, and radiology departments. Initiating and facilitating discussions of the net benefit of CT by enlisting comparisons to more familiar activities, or by conveying that the anticipated radiation dose to an exam is similar to or much less than annual background levels help resolve the concerns of many patients and providers. While radiation risk estimates at the low doses associated with CT contain considerable uncertainty, we choose to err on the side of safety by assuming a small risk exists, even though the risk at these dose levels may be zero. Thus, radiologists should individualize CT scans according to patient size and diagnostic task to ensure that maximum benefit and minimum risk is achieved. However, because the magnitude of net benefit is driven by the potential benefit of a positive exam, radiation dose should not be reduced if doing so may compromise making an accurate diagnosis. The benefits and risks of CT are also highly individualized, and require consideration of many factors by patients, clinicians, and radiologists. Radiologists can assist clinicians and patients with understanding many of these factors, including test performance, potential patient benefit, and estimates of potential risk.
Literatur
1.
Zurück zum Zitat Linet MS, Slovis TL, Miller DL, et al. (2012) Cancer risks associated with external radiation from diagnostic imaging procedures. CA Cancer J Clin. doi:10.3322/caac.21132 Linet MS, Slovis TL, Miller DL, et al. (2012) Cancer risks associated with external radiation from diagnostic imaging procedures. CA Cancer J Clin. doi:10.​3322/​caac.​21132
2.
Zurück zum Zitat Mettler FAJ, Thomadsen BR, Bhargavan M, et al. (2008) Medical radiation exposure in the U.S. in 2006: preliminary results. Health Phys 95(5):502–507PubMedCrossRef Mettler FAJ, Thomadsen BR, Bhargavan M, et al. (2008) Medical radiation exposure in the U.S. in 2006: preliminary results. Health Phys 95(5):502–507PubMedCrossRef
4.
Zurück zum Zitat Johnson CD, Chen MH, Toledano AY, et al. (2008) Accuracy of CT colonography for detection of large adenomas and cancers. N Engl J Med 359(12):1207–1217PubMedCrossRef Johnson CD, Chen MH, Toledano AY, et al. (2008) Accuracy of CT colonography for detection of large adenomas and cancers. N Engl J Med 359(12):1207–1217PubMedCrossRef
5.
Zurück zum Zitat Pickhardt PJ, Choi JR, Hwang I, et al. (2003) Computed tomographic virtual colonoscopy to screen for colorectal neoplasia in asymptomatic adults. N Engl J Med 349(23):2191–2200PubMedCrossRef Pickhardt PJ, Choi JR, Hwang I, et al. (2003) Computed tomographic virtual colonoscopy to screen for colorectal neoplasia in asymptomatic adults. N Engl J Med 349(23):2191–2200PubMedCrossRef
10.
Zurück zum Zitat McCollough CH, Leng S, Yu L, et al. (2011) CT dose index and patient dose: they are not the same thing. Radiology 259(2):311–316PubMedCrossRef McCollough CH, Leng S, Yu L, et al. (2011) CT dose index and patient dose: they are not the same thing. Radiology 259(2):311–316PubMedCrossRef
11.
12.
Zurück zum Zitat American Association of Physicists in Medicine (2011) Size-specific dose estimates (SSDE) in pediatric and adult body CT examinations (Task Group 204). College Park, MD: AAPM American Association of Physicists in Medicine (2011) Size-specific dose estimates (SSDE) in pediatric and adult body CT examinations (Task Group 204). College Park, MD: AAPM
13.
Zurück zum Zitat Martin C (2007) Effective dose: how should it be applied to medical exposures? Br J Radiol 80:639–647PubMedCrossRef Martin C (2007) Effective dose: how should it be applied to medical exposures? Br J Radiol 80:639–647PubMedCrossRef
15.
Zurück zum Zitat Cologne J, Cullings H, Furukawa K, Ross P (2010) Attributable risk for radiation in the presence of other risk factors. Health Phys 99(5):603–612PubMedCrossRef Cologne J, Cullings H, Furukawa K, Ross P (2010) Attributable risk for radiation in the presence of other risk factors. Health Phys 99(5):603–612PubMedCrossRef
16.
Zurück zum Zitat Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation (2006) Health risks from exposure to low levels of ionizing radiation, BEIR VII phase 2. Washington, DC: National Academic Press Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation (2006) Health risks from exposure to low levels of ionizing radiation, BEIR VII phase 2. Washington, DC: National Academic Press
17.
Zurück zum Zitat Preston DL, Kusumi S, Tomonaga M, et al. (1994) Cancer incidence in atomic bomb survivors. Part III. Leukemia, lymphoma and multiple myeloma, 1950–1987. Radiat Res 137(Suppl 2):S68–S97PubMedCrossRef Preston DL, Kusumi S, Tomonaga M, et al. (1994) Cancer incidence in atomic bomb survivors. Part III. Leukemia, lymphoma and multiple myeloma, 1950–1987. Radiat Res 137(Suppl 2):S68–S97PubMedCrossRef
18.
Zurück zum Zitat Preston DL, Ron E, Tokuoka S, et al. (2007) Solid cancer incidence in atomic bomb survivors: 1958–1998. Radiat Res 168(1):1–64PubMedCrossRef Preston DL, Ron E, Tokuoka S, et al. (2007) Solid cancer incidence in atomic bomb survivors: 1958–1998. Radiat Res 168(1):1–64PubMedCrossRef
19.
Zurück zum Zitat Cohen BL (2002) Cancer risk from low-level radiation. AJR Am J Roentgenol 179(5):1137–1143PubMed Cohen BL (2002) Cancer risk from low-level radiation. AJR Am J Roentgenol 179(5):1137–1143PubMed
20.
Zurück zum Zitat Little MP, Muirhead CR (1998) Curvature in the cancer mortality dose response in Japanese atomic bomb survivors: absence of evidence of threshold. Int J Radiat Biol 74(4):471–480PubMedCrossRef Little MP, Muirhead CR (1998) Curvature in the cancer mortality dose response in Japanese atomic bomb survivors: absence of evidence of threshold. Int J Radiat Biol 74(4):471–480PubMedCrossRef
21.
Zurück zum Zitat Tubiana M, Feinendegen LE, Yang C, Kaminski JM (2009) The linear no-threshold relationship is inconsistent with radiation biologic and experimental data. Radiology 251(1):13–22PubMedCrossRef Tubiana M, Feinendegen LE, Yang C, Kaminski JM (2009) The linear no-threshold relationship is inconsistent with radiation biologic and experimental data. Radiology 251(1):13–22PubMedCrossRef
22.
Zurück zum Zitat Cardis E, Vrijheid M, Blettner M, et al. (2005) Risk of cancer after low doses of ionising radiation: retrospective cohort study in 15 countries. Br Med J 331(7508):77CrossRef Cardis E, Vrijheid M, Blettner M, et al. (2005) Risk of cancer after low doses of ionising radiation: retrospective cohort study in 15 countries. Br Med J 331(7508):77CrossRef
23.
Zurück zum Zitat Canadian Nuclear Safety Commission (2011) Verifying Canadian nuclear energy worker radiation risk: a reanalysis of cancer mortality in Canadian Nuclear Energy Workers (1957–1994). Report # INFO-0811 Canadian Nuclear Safety Commission (2011) Verifying Canadian nuclear energy worker radiation risk: a reanalysis of cancer mortality in Canadian Nuclear Energy Workers (1957–1994). Report # INFO-0811
24.
Zurück zum Zitat Muirhead CR, O’Hagan JA, Haylock RG, et al. (2009) Mortality and cancer incidence following occupational radiation exposure: third analysis of the National Registry for Radiation Workers. Br J Cancer 100(1):206–212. doi:10.1038/sj.bjc.6604825 PubMedCrossRef Muirhead CR, O’Hagan JA, Haylock RG, et al. (2009) Mortality and cancer incidence following occupational radiation exposure: third analysis of the National Registry for Radiation Workers. Br J Cancer 100(1):206–212. doi:10.​1038/​sj.​bjc.​6604825 PubMedCrossRef
25.
Zurück zum Zitat Howe GR (1995) Lung cancer mortality between 1950 and 1987 after exposure to fractionated moderate-dose-rate ionizing radiation in the Canadian fluoroscopy cohort study and a comparison with lung cancer mortality in the Atomic Bomb survivors study. Radiat Res 142(3):295–304PubMedCrossRef Howe GR (1995) Lung cancer mortality between 1950 and 1987 after exposure to fractionated moderate-dose-rate ionizing radiation in the Canadian fluoroscopy cohort study and a comparison with lung cancer mortality in the Atomic Bomb survivors study. Radiat Res 142(3):295–304PubMedCrossRef
26.
Zurück zum Zitat Davis FG, Boice JD Jr, Hrubec Z, Monson RR (1989) Cancer mortality in a radiation-exposed cohort of Massachusetts tuberculosis patients. Cancer Res 49(21):6130–6136PubMed Davis FG, Boice JD Jr, Hrubec Z, Monson RR (1989) Cancer mortality in a radiation-exposed cohort of Massachusetts tuberculosis patients. Cancer Res 49(21):6130–6136PubMed
28.
Zurück zum Zitat Health Physics Society (2004) Radiation risk in perspective. Position Statement of the Health Physics Society: PS010-1 Health Physics Society (2004) Radiation risk in perspective. Position Statement of the Health Physics Society: PS010-1
29.
Zurück zum Zitat Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation, National Research Council (2006) Health risks from exposure to low levels of ionizing radiation: BEIR VII phase 2. Washington, DC: National Academies Press Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation, National Research Council (2006) Health risks from exposure to low levels of ionizing radiation: BEIR VII phase 2. Washington, DC: National Academies Press
30.
Zurück zum Zitat Gerber TC, Carr JJ, Arai AE, et al. (2009) Ionizing radiation in cardiac imaging: a science advisory from the American Heart Association Committee on Cardiac Imaging of the Council on Clinical Cardiology and Committee on Cardiovascular Imaging and Intervention of the Council on Cardiovascular Radiology and Intervention. Circulation 119(7):1056–1065. doi:10.1161/CIRCULATIONAHA.108.191650 PubMedCrossRef Gerber TC, Carr JJ, Arai AE, et al. (2009) Ionizing radiation in cardiac imaging: a science advisory from the American Heart Association Committee on Cardiac Imaging of the Council on Clinical Cardiology and Committee on Cardiovascular Imaging and Intervention of the Council on Cardiovascular Radiology and Intervention. Circulation 119(7):1056–1065. doi:10.​1161/​CIRCULATIONAHA.​108.​191650 PubMedCrossRef
31.
Zurück zum Zitat Berrington de González A, Kim KP, Knudsen AB, et al. (2011) Radiation-related cancer risks from CT colonography screening: a risk-benefit analysis. AJR Am J Roentgenol 196:816–823PubMedCrossRef Berrington de González A, Kim KP, Knudsen AB, et al. (2011) Radiation-related cancer risks from CT colonography screening: a risk-benefit analysis. AJR Am J Roentgenol 196:816–823PubMedCrossRef
32.
Zurück zum Zitat McBride J, Wardrop R, Paxton B, et al. (2012) Effect on examination ordering by physician attitude, common knowledge, and practice behavior regarding CT radiation exposure. Clin Imaging (in press) McBride J, Wardrop R, Paxton B, et al. (2012) Effect on examination ordering by physician attitude, common knowledge, and practice behavior regarding CT radiation exposure. Clin Imaging (in press)
33.
Zurück zum Zitat Bithell JF, Stewart AM (1975) Pre-natal irradiation and childhood malignancy: a review of British data from the Oxford Survey. Br J Cancer 31(3):271–287PubMedCrossRef Bithell JF, Stewart AM (1975) Pre-natal irradiation and childhood malignancy: a review of British data from the Oxford Survey. Br J Cancer 31(3):271–287PubMedCrossRef
35.
Zurück zum Zitat Marin D, Nelson RC, Rubin GD, Schindera ST (2011) Body CT: technical advances for improving safety. AJR Am J Roentgenol 197:33–41PubMedCrossRef Marin D, Nelson RC, Rubin GD, Schindera ST (2011) Body CT: technical advances for improving safety. AJR Am J Roentgenol 197:33–41PubMedCrossRef
36.
Zurück zum Zitat Hara AK, Paden RG, Silva AC, et al. (2009) Iterative reconstruction technique for reducing body radiation dose at CT: feasibility study. AJR Am J Roentgenol 193(3):764–771PubMedCrossRef Hara AK, Paden RG, Silva AC, et al. (2009) Iterative reconstruction technique for reducing body radiation dose at CT: feasibility study. AJR Am J Roentgenol 193(3):764–771PubMedCrossRef
37.
Zurück zum Zitat Guimaraes LS, Fletcher JG, Harmsen WS, et al. (2010) Appropriate patient selection at abdominal dual-energy CT using 80 kV: relationship between patient size, image noise, and image quality. Radiology 257(3):732–742. doi:10.1148/radiol.10092016 PubMedCrossRef Guimaraes LS, Fletcher JG, Harmsen WS, et al. (2010) Appropriate patient selection at abdominal dual-energy CT using 80 kV: relationship between patient size, image noise, and image quality. Radiology 257(3):732–742. doi:10.​1148/​radiol.​10092016 PubMedCrossRef
38.
Zurück zum Zitat Kaza RK, Platt JF, Al-Hawary MM, et al. (2012) CT enterography at 80 kVp with adaptive statistical iterative reconstruction versus at 120 kVp with standard reconstruction: image quality, diagnostic adequacy, and dose reduction. AJR Am J Roentgenol 198(5):1084–1092PubMedCrossRef Kaza RK, Platt JF, Al-Hawary MM, et al. (2012) CT enterography at 80 kVp with adaptive statistical iterative reconstruction versus at 120 kVp with standard reconstruction: image quality, diagnostic adequacy, and dose reduction. AJR Am J Roentgenol 198(5):1084–1092PubMedCrossRef
39.
Zurück zum Zitat Ehman EC, Guimaraes LS, Fidler JL, et al. (2012) Noise reduction to decrease radiation dose and improve conspicuity of hepatic lesions at contrast-enhanced 80-kV hepatic CT using projection space denoising. AJR American journal of roentgenology 198(2):405–411. doi:10.2214/AJR.11.6987 PubMedCrossRef Ehman EC, Guimaraes LS, Fidler JL, et al. (2012) Noise reduction to decrease radiation dose and improve conspicuity of hepatic lesions at contrast-enhanced 80-kV hepatic CT using projection space denoising. AJR American journal of roentgenology 198(2):405–411. doi:10.​2214/​AJR.​11.​6987 PubMedCrossRef
40.
Zurück zum Zitat Hough D, Fletcher J, Grant K, et al. (2012) Lowering kV to reduce radiation dose in contrast-enhanced abdominal CT: initial assessment of a prototype automatic kV selection tool. AJR Am J Roentgenol (in press) Hough D, Fletcher J, Grant K, et al. (2012) Lowering kV to reduce radiation dose in contrast-enhanced abdominal CT: initial assessment of a prototype automatic kV selection tool. AJR Am J Roentgenol (in press)
41.
Zurück zum Zitat Sahani D (March 1, 2012) Personal communication. Massachusetts General Hospital Sahani D (March 1, 2012) Personal communication. Massachusetts General Hospital
43.
Zurück zum Zitat Hartman RP, Kawashima A, Takahashi H, et al. (2012) Applications of dual-energy CT in urologic imaging: an update. Radiol Clin North Am 50:191–205PubMedCrossRef Hartman RP, Kawashima A, Takahashi H, et al. (2012) Applications of dual-energy CT in urologic imaging: an update. Radiol Clin North Am 50:191–205PubMedCrossRef
44.
Zurück zum Zitat Huprich JE, Fletcher JG, Fidler JL, et al. (2011) Prospective blinded comparison of wireless capsule endoscopy and multiphase CT enterography in obscure gastrointestinal bleeding. Radiology 260(3):744–751. doi:10.1148/radiol.11110143 PubMedCrossRef Huprich JE, Fletcher JG, Fidler JL, et al. (2011) Prospective blinded comparison of wireless capsule endoscopy and multiphase CT enterography in obscure gastrointestinal bleeding. Radiology 260(3):744–751. doi:10.​1148/​radiol.​11110143 PubMedCrossRef
46.
Zurück zum Zitat McCollough CH, Chen G, Kalender W, et al. (2012) Achieving routine submillisievert CT scanning: report from the summit on management of radiation dose in CT. Radiology. doi:10.1148/radiol.12112265 McCollough CH, Chen G, Kalender W, et al. (2012) Achieving routine submillisievert CT scanning: report from the summit on management of radiation dose in CT. Radiology. doi:10.​1148/​radiol.​12112265
47.
Zurück zum Zitat Fletcher JG, Wiersema MJ, Farrell MA, et al. (2003) Pancreatic malignancy: value of arterial, pancreatic, and hepatic phase imaging with multi-detector row CT. Radiology 229(1):81–90PubMedCrossRef Fletcher JG, Wiersema MJ, Farrell MA, et al. (2003) Pancreatic malignancy: value of arterial, pancreatic, and hepatic phase imaging with multi-detector row CT. Radiology 229(1):81–90PubMedCrossRef
49.
Zurück zum Zitat Kim K, Kim YH, Kim SY, et al. (2012) Low-dose abdominal CT for evaluating suspected appendicitis. N Engl J Med 366(17):1596–1605PubMedCrossRef Kim K, Kim YH, Kim SY, et al. (2012) Low-dose abdominal CT for evaluating suspected appendicitis. N Engl J Med 366(17):1596–1605PubMedCrossRef
50.
Zurück zum Zitat Allen BC, Baker ME, Einstein DM, et al. (2010) Effect of altering automatic exposure control settings and quality reference mAs on radiation dose, image quality, and diagnostic efficacy in MDCT enterography of active inflammatory Crohn’s disease. AJR Am J Roentgenol 195(1):89–100. doi:10.2214/AJR.09.3611 PubMedCrossRef Allen BC, Baker ME, Einstein DM, et al. (2010) Effect of altering automatic exposure control settings and quality reference mAs on radiation dose, image quality, and diagnostic efficacy in MDCT enterography of active inflammatory Crohn’s disease. AJR Am J Roentgenol 195(1):89–100. doi:10.​2214/​AJR.​09.​3611 PubMedCrossRef
51.
Zurück zum Zitat Kambadakone AR, Prakash P, Hahn PF, Sahani DV (2010) Low-dose CT examinations in Crohn’s disease: impact on image quality, diagnostic performance, and radiation dose. AJR Am J Roentgenol 195(1):78–88. doi:10.2214/AJR.09.3420 PubMedCrossRef Kambadakone AR, Prakash P, Hahn PF, Sahani DV (2010) Low-dose CT examinations in Crohn’s disease: impact on image quality, diagnostic performance, and radiation dose. AJR Am J Roentgenol 195(1):78–88. doi:10.​2214/​AJR.​09.​3420 PubMedCrossRef
52.
Zurück zum Zitat Seo H, Lee KH, Kim HJ, et al. (2009) Diagnosis of acute appendicitis with sliding slab ray-sum interpretation of low-dose unenhanced CT and standard-dose i.v. contrast-enhanced CT scans. AJR Am J Roentgenol 193(1):96–105. doi:10.2214/AJR.08.1237 PubMedCrossRef Seo H, Lee KH, Kim HJ, et al. (2009) Diagnosis of acute appendicitis with sliding slab ray-sum interpretation of low-dose unenhanced CT and standard-dose i.v. contrast-enhanced CT scans. AJR Am J Roentgenol 193(1):96–105. doi:10.​2214/​AJR.​08.​1237 PubMedCrossRef
53.
Zurück zum Zitat Niemann T, Kollmann T, Bongartz G (2008) Diagnostic performance of low-dose CT for the detection of urolithiasis: a meta-analysis. AJR Am J Roentgenol 191(2):396–401PubMedCrossRef Niemann T, Kollmann T, Bongartz G (2008) Diagnostic performance of low-dose CT for the detection of urolithiasis: a meta-analysis. AJR Am J Roentgenol 191(2):396–401PubMedCrossRef
Metadaten
Titel
Perspective on radiation risk in CT imaging
verfasst von
Joel G. Fletcher
James M. Kofler
John A. Coburn
David H. Bruining
Cynthia H. McCollough
Publikationsdatum
01.02.2013
Verlag
Springer-Verlag
Erschienen in
Abdominal Radiology / Ausgabe 1/2013
Print ISSN: 2366-004X
Elektronische ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-012-9933-z

Weitere Artikel der Ausgabe 1/2013

Abdominal Radiology 1/2013 Zur Ausgabe

Akuter Schwindel: Wann lohnt sich eine MRT?

28.04.2024 Schwindel Nachrichten

Akuter Schwindel stellt oft eine diagnostische Herausforderung dar. Wie nützlich dabei eine MRT ist, hat eine Studie aus Finnland untersucht. Immerhin einer von sechs Patienten wurde mit akutem ischämischem Schlaganfall diagnostiziert.

Screening-Mammografie offenbart erhöhtes Herz-Kreislauf-Risiko

26.04.2024 Mammografie Nachrichten

Routinemäßige Mammografien helfen, Brustkrebs frühzeitig zu erkennen. Anhand der Röntgenuntersuchung lassen sich aber auch kardiovaskuläre Risikopatientinnen identifizieren. Als zuverlässiger Anhaltspunkt gilt die Verkalkung der Brustarterien.

S3-Leitlinie zu Pankreaskrebs aktualisiert

23.04.2024 Pankreaskarzinom Nachrichten

Die Empfehlungen zur Therapie des Pankreaskarzinoms wurden um zwei Off-Label-Anwendungen erweitert. Und auch im Bereich der Früherkennung gibt es Aktualisierungen.

Fünf Dinge, die im Kindernotfall besser zu unterlassen sind

18.04.2024 Pädiatrische Notfallmedizin Nachrichten

Im Choosing-Wisely-Programm, das für die deutsche Initiative „Klug entscheiden“ Pate gestanden hat, sind erstmals Empfehlungen zum Umgang mit Notfällen von Kindern erschienen. Fünf Dinge gilt es demnach zu vermeiden.

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.