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Erschienen in: Journal of Genetic Counseling 1/2014

01.02.2014 | Case Presentation

Predictive Genetic Testing of a Bone Marrow Recipient–Ethical Issues Involving Unexpected Results, Gender Issues, Test Accuracy, and Implications for the Donor

verfasst von: A. Sexton, L. Rawlings, M. Jenkins, I. Winship

Erschienen in: Journal of Genetic Counseling | Ausgabe 1/2014

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Abstract

We present a case where an apparently straightforward Lynch syndrome predictive genetic test of DNA from a blood sample from a woman yielded an unexpected result of X/Y chromosome imbalance. Furthermore, it demonstrates the complexities of genetic testing in people who have had bone marrow transplants. This highlights the potential for multiple ethical and counselling challenges, including the inadvertent testing of the donor. Good communication between clinics and laboratories is essential to overcome such challenges and to minimise the provision of false results.
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Metadaten
Titel
Predictive Genetic Testing of a Bone Marrow Recipient–Ethical Issues Involving Unexpected Results, Gender Issues, Test Accuracy, and Implications for the Donor
verfasst von
A. Sexton
L. Rawlings
M. Jenkins
I. Winship
Publikationsdatum
01.02.2014
Verlag
Springer US
Erschienen in
Journal of Genetic Counseling / Ausgabe 1/2014
Print ISSN: 1059-7700
Elektronische ISSN: 1573-3599
DOI
https://doi.org/10.1007/s10897-013-9643-x

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